Given the development of insects’resistance and deteriorative ecological environment,the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management.H...Given the development of insects’resistance and deteriorative ecological environment,the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management.Herein,a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group were designed and synthesized.Their insecticidal potency was assayed against beet armyworm(Spodoptera exigua).Moreover,the structure-activity relationship of these new compounds was also discussed.Of them,compound 15g exhibited potential insecticidal activity.Because of the excellent efficacy against a series of Lepidoptera and low toxicity to mammals,compound 15g,namely tetrachlorantraniliprole,has been developed and launched into the market as an insecticide.展开更多
基金supported by the National Key Research&Development Pillar Program of China during the 13th Five-Year Plan Period(Grant No.2016YFD0300708,2016YFD0300709).
文摘Given the development of insects’resistance and deteriorative ecological environment,the discovery of insecticides with a new mode of action has been proven to be an important tool for comprehensive pest management.Herein,a novel anthranilic diamides containing 3,5-dichloropyridylpyrazole group were designed and synthesized.Their insecticidal potency was assayed against beet armyworm(Spodoptera exigua).Moreover,the structure-activity relationship of these new compounds was also discussed.Of them,compound 15g exhibited potential insecticidal activity.Because of the excellent efficacy against a series of Lepidoptera and low toxicity to mammals,compound 15g,namely tetrachlorantraniliprole,has been developed and launched into the market as an insecticide.
