An acrylic modified pumpkin vine-based biochar(p-PVB-PAA) is synthesized by non-thermal plasma-grafting modification of pumpkin vine-based biochar(PVB) for the removal of uranyl from an aqueous solution. Microscopic c...An acrylic modified pumpkin vine-based biochar(p-PVB-PAA) is synthesized by non-thermal plasma-grafting modification of pumpkin vine-based biochar(PVB) for the removal of uranyl from an aqueous solution. Microscopic characterization reveals that compared to PVB the surface of p-PVBPAA has more oxygen-containing functional groups by strong chemical bonding and the specific surface area is increased to 275.3 m^2 g^-1 from 3.8 m^2g^-1. It is found that p-PVB-PAA showed a much higher maximum adsorption capacity for uranyl from aqueous solutions than PVB, which were207.02 mg g^-1 and 67.58 mg g^-1 at pH=5 and 298 K, respectively. Moreover, the adsorption behavior follows a pseudo-second-order kinetics model and the Langmuir adsorption model.Additionally, macroscopic experiments and spectroscopic studies verified that the significantly improved adsorption performance of the p-PVB-PAA is due to surface complexation and electrostatic interactions. Furthermore, the very high removal efficiency and excellent regeneration ability(the percentage of the removal still remained at nearly 90% after five cycles) makes this low-cost, easily obtained, and environmentally friendly material attractive for commercial application.展开更多
Objective:Diabetic retinopathy(DR) is the retinal consequence of chronic progressive diabetic microvascular leakage and occlusion.Non-proliferating diabetic retinopathy(NPDR) is the early stage of DR.It eventually occ...Objective:Diabetic retinopathy(DR) is the retinal consequence of chronic progressive diabetic microvascular leakage and occlusion.Non-proliferating diabetic retinopathy(NPDR) is the early stage of DR.It eventually occurs to some degree in all patients with diabetes mellitus.In recent years,many clinical trials have shown that Compound Danshen Dripping Pill(CDDP) may be associated with the improvement of NPDR symptoms.The aim of this study was to quantitatively summarize the association between CDDP and the therapeutic effects of NPDR.Methods:It was conducted that a systematic literature search of Pub Med,Web of Science,CNKI,VIP and Wanfang Data updated in June 2020 with the following search terms:"diabetic retinopathy° or"retinopathy° or "DR° or "NPDR°,in combination with "Compound Danshen Dripping Pill° or "Salvia miltiorrhiza° or "Danshen°.Risk ratio(RR) and weighted mean difference(WMD) with their 95% confidence interval(CI) was calculated between treatment and control groups.The sensitivity analyses were undertaken by removing each individual study when high heterogeneity appeared.Subgroup analysis,Metaregression,and publication bias analysis were also conducted.The strength of evidence was evaluated with the Grading of Recommendation,Assessment,Development,and Evaluation(GRADE) method.Results:Twenty-six RCTs involving 2047 subjects were included to conduct a Meta-analysis after screening the studies,extracting the data,and assessing the study quality.The Stata15.0 software was utilized for processing.Meta-analysis indicated that curative effects of treatment group with CDDP was significantly better than control [RR = 0.54,95% CI(0.40,0.73);moderate-quality evidence].In addition,the results showed that CDDP was significantly associated with improving retinal hemorrhages[WMD =-0.62,95% CI(-0.78,-0.46);low-quality evidence],the vision [WMD = 0.14,and 95% CI(0.09,0.19),low-quality evidence],fundus fluorescence angiography [RR = 0.37 and 95% CI(0.23,0.60);low-quality evidence],reduction of retinal microaneurysm [WMD =-3.74 and 95% CI(-4.38,-3.11);moderate-quality evidence],hemangioma volume [WMD =-3.15,95%CI(-3.45,-2.85);moderate-quality evidence],macular thickness [WMD =-5.52,95%CI =(-64.27,-48.78);low-quality evidence],mean defect [WMD =-1.65 and 95% CI(-1.95,-1.34);very low-quality evidence],fasting blooding glucose [WMD =-0.95,95% CI(-1.19,-0.70);low-quality evidence),hemoglobin A1c[WMD =-0.62,95% CI(-0.93,-0.30);low-quality evidence],high sensitive C reaction protein[WMD =-5.66,95% CI(-8.01,-3.31);low-quality evidence].Sensitivity,subgroup,and Metaregression analyses were also assessed.Conclusion:The study demonstrated that CDDP has beneficial clinical effects for treating NPDR and improve the vision.Moreover,it indicated that oral CDDP in NPDR patients led to significant regulation of serum level of fasting blooding glucose,hemoglobin A1c and high sensitive C reaction protein,which was associated with the pathogenesis of NPDR.However,high-quality and large randomized clinical trials will be needed to prove the consequence in future.展开更多
Semiconductor sensitized solar cells(SSSCs) are promising candidates for the third generation of cost-effective photovoltaic solar cells and it is important to develop a group of robust, environment-friendly and visib...Semiconductor sensitized solar cells(SSSCs) are promising candidates for the third generation of cost-effective photovoltaic solar cells and it is important to develop a group of robust, environment-friendly and visible-light-responsive semiconductor sensitizers. In this paper, we first synthesized bismuth vanadate(Bi VO4) quantum dots by employing facile successive ionic layer adsorption and reaction(SILAR) deposition technique, which we then used as a sensitizer for solar energy conversion. The preliminary optimised oxide SSSC showed an efficiency of 0.36%, nearly 2 orders of magnitude enhancement compared with bare Ti O2, due to the narrow bandgap absorption of Bi VO4 quantum dots and intimate contact with the oxide substrate. This result not only demonstrates a simple method to prepare Bi VO4 quantum dots based solar cells, but also provides important insights into the low bandgap oxide SSSCs.展开更多
基金financially supported by the National High Technology Research and Development Program of China (No. 21677146)National Natural Science Foundation of China (Nos. 21876178, U1607102)the Anhui Provincial Natural Science Foundation (No. 1708085MB31)
文摘An acrylic modified pumpkin vine-based biochar(p-PVB-PAA) is synthesized by non-thermal plasma-grafting modification of pumpkin vine-based biochar(PVB) for the removal of uranyl from an aqueous solution. Microscopic characterization reveals that compared to PVB the surface of p-PVBPAA has more oxygen-containing functional groups by strong chemical bonding and the specific surface area is increased to 275.3 m^2 g^-1 from 3.8 m^2g^-1. It is found that p-PVB-PAA showed a much higher maximum adsorption capacity for uranyl from aqueous solutions than PVB, which were207.02 mg g^-1 and 67.58 mg g^-1 at pH=5 and 298 K, respectively. Moreover, the adsorption behavior follows a pseudo-second-order kinetics model and the Langmuir adsorption model.Additionally, macroscopic experiments and spectroscopic studies verified that the significantly improved adsorption performance of the p-PVB-PAA is due to surface complexation and electrostatic interactions. Furthermore, the very high removal efficiency and excellent regeneration ability(the percentage of the removal still remained at nearly 90% after five cycles) makes this low-cost, easily obtained, and environmentally friendly material attractive for commercial application.
基金supported by the National Science and Technology Major Project for Significant New Drugs Development(2017ZX09301005)
文摘Objective:Diabetic retinopathy(DR) is the retinal consequence of chronic progressive diabetic microvascular leakage and occlusion.Non-proliferating diabetic retinopathy(NPDR) is the early stage of DR.It eventually occurs to some degree in all patients with diabetes mellitus.In recent years,many clinical trials have shown that Compound Danshen Dripping Pill(CDDP) may be associated with the improvement of NPDR symptoms.The aim of this study was to quantitatively summarize the association between CDDP and the therapeutic effects of NPDR.Methods:It was conducted that a systematic literature search of Pub Med,Web of Science,CNKI,VIP and Wanfang Data updated in June 2020 with the following search terms:"diabetic retinopathy° or"retinopathy° or "DR° or "NPDR°,in combination with "Compound Danshen Dripping Pill° or "Salvia miltiorrhiza° or "Danshen°.Risk ratio(RR) and weighted mean difference(WMD) with their 95% confidence interval(CI) was calculated between treatment and control groups.The sensitivity analyses were undertaken by removing each individual study when high heterogeneity appeared.Subgroup analysis,Metaregression,and publication bias analysis were also conducted.The strength of evidence was evaluated with the Grading of Recommendation,Assessment,Development,and Evaluation(GRADE) method.Results:Twenty-six RCTs involving 2047 subjects were included to conduct a Meta-analysis after screening the studies,extracting the data,and assessing the study quality.The Stata15.0 software was utilized for processing.Meta-analysis indicated that curative effects of treatment group with CDDP was significantly better than control [RR = 0.54,95% CI(0.40,0.73);moderate-quality evidence].In addition,the results showed that CDDP was significantly associated with improving retinal hemorrhages[WMD =-0.62,95% CI(-0.78,-0.46);low-quality evidence],the vision [WMD = 0.14,and 95% CI(0.09,0.19),low-quality evidence],fundus fluorescence angiography [RR = 0.37 and 95% CI(0.23,0.60);low-quality evidence],reduction of retinal microaneurysm [WMD =-3.74 and 95% CI(-4.38,-3.11);moderate-quality evidence],hemangioma volume [WMD =-3.15,95%CI(-3.45,-2.85);moderate-quality evidence],macular thickness [WMD =-5.52,95%CI =(-64.27,-48.78);low-quality evidence],mean defect [WMD =-1.65 and 95% CI(-1.95,-1.34);very low-quality evidence],fasting blooding glucose [WMD =-0.95,95% CI(-1.19,-0.70);low-quality evidence),hemoglobin A1c[WMD =-0.62,95% CI(-0.93,-0.30);low-quality evidence],high sensitive C reaction protein[WMD =-5.66,95% CI(-8.01,-3.31);low-quality evidence].Sensitivity,subgroup,and Metaregression analyses were also assessed.Conclusion:The study demonstrated that CDDP has beneficial clinical effects for treating NPDR and improve the vision.Moreover,it indicated that oral CDDP in NPDR patients led to significant regulation of serum level of fasting blooding glucose,hemoglobin A1c and high sensitive C reaction protein,which was associated with the pathogenesis of NPDR.However,high-quality and large randomized clinical trials will be needed to prove the consequence in future.
基金supported by the National Basic Research Program of China(2011CBA00700)the National High Technology Research and Development Program of China(2011AA050527)the National Natural Science Foundation of China(21403247,21173228,21103197)
文摘Semiconductor sensitized solar cells(SSSCs) are promising candidates for the third generation of cost-effective photovoltaic solar cells and it is important to develop a group of robust, environment-friendly and visible-light-responsive semiconductor sensitizers. In this paper, we first synthesized bismuth vanadate(Bi VO4) quantum dots by employing facile successive ionic layer adsorption and reaction(SILAR) deposition technique, which we then used as a sensitizer for solar energy conversion. The preliminary optimised oxide SSSC showed an efficiency of 0.36%, nearly 2 orders of magnitude enhancement compared with bare Ti O2, due to the narrow bandgap absorption of Bi VO4 quantum dots and intimate contact with the oxide substrate. This result not only demonstrates a simple method to prepare Bi VO4 quantum dots based solar cells, but also provides important insights into the low bandgap oxide SSSCs.
