Dear Editor,Liposarcoma is a common soft tissue malignancy in adults.It most commonly occurs in the deep soft tis-sue of the extremities and retroperitoneum.Primary intrathoracic liposarcoma is rare,represents 2.7%of ...Dear Editor,Liposarcoma is a common soft tissue malignancy in adults.It most commonly occurs in the deep soft tis-sue of the extremities and retroperitoneum.Primary intrathoracic liposarcoma is rare,represents 2.7%of all liposarcomas[1].According to the distinct tumor loca-tions,it can be divided into mediastinal,pleural,and pulmonary liposarcomas.Most literature has reviewed the clinicopathological or molecular cytogenetic char-acteristics of mediastinal and thoracic liposarcomas[2,3].However,intrathoracic liposarcoma is poorly docu-mented because of its rarity.Complete surgical resection is thought to be the best treatment for primary intratho-racic liposarcoma,but the impact of radiotherapy and systemic therapy remains unclear.Therefore,we ana-lyzed the clinicopathological data of 31 patients with primary intrathoracic liposarcoma who were treated in the Cancer Hospital of Chinese Academy of Medical Sci-ences between October 1970 and July 2015 to explore their clinicopathologic features and treatment outcomes(Additional file 1:Table S1).展开更多
文摘Dear Editor,Liposarcoma is a common soft tissue malignancy in adults.It most commonly occurs in the deep soft tis-sue of the extremities and retroperitoneum.Primary intrathoracic liposarcoma is rare,represents 2.7%of all liposarcomas[1].According to the distinct tumor loca-tions,it can be divided into mediastinal,pleural,and pulmonary liposarcomas.Most literature has reviewed the clinicopathological or molecular cytogenetic char-acteristics of mediastinal and thoracic liposarcomas[2,3].However,intrathoracic liposarcoma is poorly docu-mented because of its rarity.Complete surgical resection is thought to be the best treatment for primary intratho-racic liposarcoma,but the impact of radiotherapy and systemic therapy remains unclear.Therefore,we ana-lyzed the clinicopathological data of 31 patients with primary intrathoracic liposarcoma who were treated in the Cancer Hospital of Chinese Academy of Medical Sci-ences between October 1970 and July 2015 to explore their clinicopathologic features and treatment outcomes(Additional file 1:Table S1).