Embryonic stem cells （ESCs） obtained from blastocysts can self-renew and potentially differentiate into three germ layers, thus acting as a promising platform in cell-replacement therapies and developmental research...Embryonic stem cells （ESCs） obtained from blastocysts can self-renew and potentially differentiate into three germ layers, thus acting as a promising platform in cell-replacement therapies and developmental research （Evans and Kaufman, 1981; Thomson et al., 1998）. Neural specification of ESCs has been extensively studied due to their superior value as a cellular resource in studying neurodegenerative diseases （Tao and Zhang, 2016）.展开更多
基金funded by the National Natural Science Foundation of China(Nos.31501186 and 31671538 to L.S.)the Natural Science Foundation of Tianjin(15JCZDJC65300 to L.S.)the Beijing Nova Program(No.2015A011 to Y.Y.)
文摘Embryonic stem cells （ESCs） obtained from blastocysts can self-renew and potentially differentiate into three germ layers, thus acting as a promising platform in cell-replacement therapies and developmental research （Evans and Kaufman, 1981; Thomson et al., 1998）. Neural specification of ESCs has been extensively studied due to their superior value as a cellular resource in studying neurodegenerative diseases （Tao and Zhang, 2016）.
