1.Introduction Sarcoidosis is a disease that involves multiple systems and organs and is characterized by non-caseous necrotizing granulomas whose etiology is not fully understood.1 About 25%–80%of patients have eye ...1.Introduction Sarcoidosis is a disease that involves multiple systems and organs and is characterized by non-caseous necrotizing granulomas whose etiology is not fully understood.1 About 25%–80%of patients have eye and adnexal involvement.2 Uveitis,secondary glaucoma,cataracts,and macular edema are the most common complications of ocular sarcoidosis.3 Sarcoid uveitis refers to uveitis that occurs in patients with sarcoidosis and typically manifests as granulomatous anterior uveitis,posterior uveitis,or panuveitis.Symptoms of sarcoid uveitis include blurred vision,eye pain,photophobia,and tearing.In the anterior segment,iris nodules or mutton-fat keratic precipitates(KPs)are generally the most common clinical signs.In the vitreous cavity,the typical appearance is a snowball-like vitreous opacity.The fundus typically manifests as peripheral chorioretinal granulomas and peripheral phlebitis.Herein,we present a case of sarcoid uveitis with fungal endophthalmitis-like vitreitis.展开更多
基金This work was supported by the National Natural Science Foundation of China(81870648,82070949,82000886)and Natural Science Foundation of Zhejiang Province(No.LQ20H120011).
文摘1.Introduction Sarcoidosis is a disease that involves multiple systems and organs and is characterized by non-caseous necrotizing granulomas whose etiology is not fully understood.1 About 25%–80%of patients have eye and adnexal involvement.2 Uveitis,secondary glaucoma,cataracts,and macular edema are the most common complications of ocular sarcoidosis.3 Sarcoid uveitis refers to uveitis that occurs in patients with sarcoidosis and typically manifests as granulomatous anterior uveitis,posterior uveitis,or panuveitis.Symptoms of sarcoid uveitis include blurred vision,eye pain,photophobia,and tearing.In the anterior segment,iris nodules or mutton-fat keratic precipitates(KPs)are generally the most common clinical signs.In the vitreous cavity,the typical appearance is a snowball-like vitreous opacity.The fundus typically manifests as peripheral chorioretinal granulomas and peripheral phlebitis.Herein,we present a case of sarcoid uveitis with fungal endophthalmitis-like vitreitis.
