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GIPC1 promotes tumor growth and migration in gastric cancer via activating PDGFR/PI3K/AKT signaling
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作者 TINGTING LI WEI ZHONG +10 位作者 LIU YANG zhiyu zhao LI WANG CONG LIU WANYUN LI HAIYAN LV SHENGYU WANG JIANGHUA YAN TING WU GANG SONG FANGHONG LUO 《Oncology Research》 SCIE 2024年第2期361-371,共11页
The high mortality rate associated with gastric cancer(GC)has resulted in an urgent need to identify novel therapeutic targets for GC.This study aimed to investigate whether GAIP interacting protein,C terminus 1(GIPC1... The high mortality rate associated with gastric cancer(GC)has resulted in an urgent need to identify novel therapeutic targets for GC.This study aimed to investigate whether GAIP interacting protein,C terminus 1(GIPC1)represents a therapeutic target and its regulating mechanism in GC.GIPC1 expression was elevated in GC tissues,liver metastasis tissues,and lymph node metastases.GIPC1 knockdown or GIPC1 blocking peptide blocked the platelet-derived growth factor receptor(PDGFR)/PI3K/AKT signaling pathway,and inhibited the proliferation and migration of GC cells.Conversely,GIPC1 overexpression markedly activated the PDGFR/PI3K/AKT signaling pathway,and promoted GC cell proliferation and migration.Furthermore,platelet-derived growth factor subunit BB(PDGF-BB)cytokines and the AKT inhibitor attenuated the effect of differential GIPC1 expression.Moreover,GIPC1 silencing decreased tumor growth and migration in BALB/c nude mice,while GIPC1 overexpression had contrasting effects.Taken together,our findings suggest that GIPC1 functions as an oncogene in GC and plays a central role in regulating cell proliferation and migration via the PDGFR/PI3K/AKT signaling pathway. 展开更多
关键词 GIPC1 PDGFR Gastric cancer Proliferation MIGRATION
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A graphene-enhanced high-barrier and fast-curing film for deep in situ condition preserved coring in coal seams
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作者 Dongsheng Yang zhiyu zhao +4 位作者 Yifan Wu Liangyu Zhu Jingli Lu Tao Liu Heping Xie 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2023年第11期1365-1376,共12页
Scientific research on deep in situ resources is highly important to the theory and technology system construction for deep in-situ resource exploitation.To obtain high-condition preserved core samples,it is vital to ... Scientific research on deep in situ resources is highly important to the theory and technology system construction for deep in-situ resource exploitation.To obtain high-condition preserved core samples,it is vital to maintain the original material,humidity and luminous flux information inside the core.Therefore,this study proposes a research and development strategy for a high-toughness and highbarrier sealing film based on the molecular structure design and filler synergistic enhancement via a deep solid-state sealing film using in situ substance preservation(ISP),in situ moisture preservation(IMP)and in situ light preservation(ILP)coring principles.A graphene/epoxy composite sealing film with a high barrier,high strength and high toughness was developed.The oxygen permeability of the film was 0.23 cm^(3)/(m^(2)·d),the water vapor permeability was 1.26 g/(m^(2)·d),and the light transmittance was 0.The tensile strength reached 15.4 MPa,and the toughness was 5242.9 kJ/m^(3).The results from the film substance and moisture preservation performance verification experiments showed that the sealing film had an excellent sealing effect on small molecules,such as water,alkanes and even ions,which further verified that the sealing film greatly contributed to the maintenance and preservation of deep in-situ resource reserves and abundance. 展开更多
关键词 ISP-IMP-ILP-coring Graphene/epoxy resin composites Sealing film
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Electrochemical CO_(2) mineralization for red mud treatment driven by hydrogen-cycled membrane electrolysis 被引量:2
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作者 Heping Xie Yunpeng Wang +6 位作者 Tao Liu Yifan Wu Wenchuan Jiang Cheng Lan zhiyu zhao Liangyu Zhu Dongsheng Yang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2022年第3期14-23,共10页
CO_(2)mineralization as a promising CO_(2)mitigation strategy can employ industrial alkaline solid wastes to achieve net emission reduction of atmospheric CO_(2).The red mud is a strong alkalinity waste residue produc... CO_(2)mineralization as a promising CO_(2)mitigation strategy can employ industrial alkaline solid wastes to achieve net emission reduction of atmospheric CO_(2).The red mud is a strong alkalinity waste residue produced from the aluminum industry by the Bayer process which has the potential for the industrial CO_(2)large scale treatment.However,limited by complex components of red mud and harsh operating conditions,it is challenging to directly mineralize CO_(2)using red mud to recover carbon and sodium resources and to produce mineralized products simultaneously with high economic value efficiently.Herein,we propose a novel electrochemical CO_(2)mineralization strategy for red mud treatment driven by hydrogen-cycled membrane electrolysis,realizing mineralization of CO_(2)efficiently and recovery of carbon and sodium resources with economic value.The system utilizes H_(2)as the redox-active proton carrier to drive the cathode and anode to generate OH^(-) and H^(+) at low voltage,respectively.The H^(+) plays as a neutralizer for the alkalinity of red mud and the OH^(-) is used to mineralize CO_(2)into generate highpurity NaHCO_(3)product.We verify that the system can effectively recover carbon and sodium resources in red mud treatment process,which shows that the average electrolysis efficiency is 95.3%with highpurity(99.4%)NaHCO_(3)product obtained.The low electrolysis voltage of 0.453 V is achieved at10 mA·cm^(-2) in this system indicates a potential low energy consumption industrial process.Further,we successfully demonstrate that this process has the ability of direct efficient mineralization of flue gas CO_(2)(15%volume)without extra capturing,being a novel potential strategy for carbon neutralization. 展开更多
关键词 CO_(2)mineralization Red mud ELECTROLYSIS Waste treatment Flue gas
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Application study on plasma ignition in aeroengine strut–cavity–injector integrated afterburner
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作者 Li Fei Bingbing zhao +5 位作者 Xiong Liu Liming He Jun Deng Jianping Lei Ziehen zhao zhiyu zhao 《Plasma Science and Technology》 SCIE EI CAS CSCD 2021年第10期186-196,共11页
To increase the thrust-weight ratio in next-generation military aeroengines,a new integrated afterburner was designed in this study.The integrated structure of a combined strut–cavity–injector was applied to the aft... To increase the thrust-weight ratio in next-generation military aeroengines,a new integrated afterburner was designed in this study.The integrated structure of a combined strut–cavity–injector was applied to the afterburner.To improve ignition characteristics in the afterburner,a new method using a plasma jet igniter was developed and optimized for application in the integrated afterburner.The effects of traditional spark igniters and plasma jet igniters on ignition processes and ignition characteristics of afterburners were studied and compared with the proposed design.The experimental results show that the strut–cavity–injector combination can achieve stable combustion,and plasma ignition can improve ignition characteristics.Compared with conventional spark ignition,plasma ignition reduced the ignition delay time by 67 ms.Additionally,the ignition delay time was reduced by increasing the inlet velocity and reducing the excess air coefficient.This investigation provides an effective and feasible method to apply plasma ignition in aeroengine afterburners and has potential engineering applications. 展开更多
关键词 integrated afterburner AEROENGINE plasma ignition ignition process ignition characteristics
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CEPC Technical Design Report 被引量:1
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作者 Waleed Abdallah Tiago Carlos Adorno de Freitas +1111 位作者 Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed Xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai Yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci Xiao-Jun Bi Yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert Maarten Boonekamp Marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya Masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia Hua Cai Wenyong Cai Wujun Cai Yijian Cai Yizhou Cai Yuchen Cai Haiying Cai Huacheng Cai Lorenzo Calibbi Junsong Cang Guofu Cao Jianshe Cao Antoine Chance Xuejun Chang Yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che Yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen Gang Chen Guoming Chen Hua-Xing Chen Huirun Chen Jinhui Chen Ji-Yuan Chen Kai Chen Mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen Xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen Yukai Chen Zelin Chen Zilin Chen Gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng Huajie Cheng Shan Cheng Tongguang Cheng Yunlong Chi Pietro Chimenti Wen Han Chiu Guk Cho Ming-Chung Chu Xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui Xiaohao Cui zhaoyuan Cui Brunella D'Anzi Ling-Yun Dai Xinchen Dai Xuwen Dai Antonio De Maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong Jianing Dong Jing Dong Lan Dong Mingyi Dong Xu Dong Yipei Dong Yubing Dong Milos Dordevic Marco Drewes Mingxuan Du Mingxuan Du Qianqian Du Xiaokang Du Yanyan Du Yong Du Yunfei Du Chun-Gui Duan Zhe Duan Yahor Dydyshka Ulrik Egede Walaa Elmetenawee Yun Eo Ka Yan Fan Kuanjun Fan Yunyun Fan Bo Fang Shuangshi Fang Yuquan Fang Ada Farilla Riccardo Farinelli Muhammad Farooq Angeles Faus Golfe Almaz Fazliakhmetov Rujun Fei Bo Feng Chong Feng Junhua Feng Xu Feng Zhuoran Feng Zhuoran Feng Luis Roberto Flores Castillo Etienne Forest Andrew Fowlie Harald Fox Hai-Bing Fu Jinyu Fu Benjamin Fuks Yoshihiro Funakoshi Emidio Gabrielli Nan Gan Li Gang Jie Gao Meisen Gao Wenbin Gao Wenchun Gao Yu Gao Yuanning Gao Zhanxiang Gao Yanyan Gao Kun Ge Shao-Feng Ge Zhenwu Ge Li-Sheng Geng Qinglin Geng Chao-Qiang Geng Swagata Ghosh Antonio Gioiosa Leonid Gladilin Ti Gong Stefania Gori Quanbu Gou Sebastian Grinstein Chenxi Gu Gerardo Guillermo Joao Guimaraes da Costa Dizhou Guo Fangyi Guo Jiacheng Guo Jun Guo Lei Guo Lei Guo Xia Guo Xin-Heng Guo Xinyang Guo Yun Guo Yunqiang Guo Yuping Guo Zhi-Hui Guo Alejandro Gutierrez-Rodriguez Seungkyu Ha Noman Habib Jan Hajer Francois Hammer Chengcheng Han Huayong Han Jifeng Han Liang Han Liangliang Han Ruixiong Han Yang Han Yezi Han Yuanying Han Tao Han Jiankui Hao Xiqing Hao Xiqing Hao Chuanqi He Dayong He Dongbing He Guangyuan He Hong-Jian He Jibo He Jun He Longyan He Xiang He Xiao-Gang He Zhenqiang He Klaus Heinemann Sven Heinemeyer Yuekun Heng Maria A.Hernandez-Ruiz Jiamin Hong Yuenkeung Hor George W.S.Hou Xiantao Hou Xiaonan Hou Zhilong Hou Suen Hou Caishi Hu Chen Hu Dake Hu Haiming Hu Jiagen Hu Jun Hu Kun Hu Shouyang Hu Yongcai Hu Yu Hu Zhen Hu Zhehao Hua Jianfei Hua Chao-Shang Huang Fa Peng Huang Guangshun Huang Jinshu Huang Ke Huang Liangsheng Huang Shuhui Huang Xingtao Huang Xu-Guang Huang Yanping Huang Yonggang Huang Yongsheng Huang Zimiao Huang Chen Huanyuan Changgi Hua Jiaqi Hui Lihua Huo Talab Hussain Kyuyeong Hwang Ara loannisian Munawar Iqbal Paul Jackson Shahriyar Jafarzade Haeun Jang Seoyun Jang Daheng Ji Qingping Ji Quan Ji Xiaolu Ji Jingguang Jia Jinsheng Jia Xuewei Jia Zihang Ja Cailian Jiang Han Ren Jiang Houbing Jiang Jun Jiang Xiaowei Jiang Xin Jiang Xuhui Jiang Yongcheng Jiang Zhongjian Jiang Cheng Jiang Ruiqi Jiao Dapeng Jin Shan Jin Song Jin Yi Jin Junji Jis Sunghoon Jung Goran Kacarevic Eric Kajfasz Lidia Kalinovskaya Aleksei Kampf Wen Kang Xian-Wei Kang Xiaolin Kang Biswajit Karmakar Zhiyong Ke Rijeesh Keloth Alamgir Khan Hamzeh Khanpour Khanchai Khosonthongkee KhanchaiKhosonthongkee Bobae Kim Dongwoon Kim Mi Ran Kim Minsuk Kim Sungwon Kim On Kim Michael Klasen Sanghyun Ko Ivan Koop Vitaliy Kornienko Bryan Kortman Gennady Kozlov Shiqing Kuang Mukesh Kumar Chia Ming Kuo Tsz Hong Kwok Fran cois Sylvain Ren Lagarde Pei-Zhu Lai Imad Laktineh Xiaofei Lan Zuxiu Lan Lia Lavezzi Justin Lee Junghyun Lee Sehwook Lee Ge Lei Roy Lemmon longxiang Leng Sze Ching Leung Hai Tao Li Bingzhi Li Bo Li Bo Li Changhong Li Chao Li Cheng Li Cheng Li Chunhua Li Cui Li Dazhang Li Dikai Li Fei Li Gang Li Gang Li Gang Li Gaosong Li Haibo Li Haifeng Li Hai-Jun Li Haotian Li Hengne Li Honglei Li Huijing Li Jialin Li Jingyi Li Jinmian Li Jun Li Leyi Li Liang Li Ling Li Mei Li Meng Li Minxian Li Pei-Rong Li Qiang Li Shaopeng Li Shenghe Li Shu Li Shuo Li Teng Li Tiange Li Tong Li Weichang Li Weidong Li Wenjun Li Xiaoling Li Xiaomei Li Xiaonan Li Xiaoping Li Xiaoting Li Xin Li Xinqiang Li Xuekang Li Yang Li Yanwei Li Yiming Li Ying Li Ying-Ying Li Yonggang Li Yonglin Li Yufeng Li Yuhui Li Zhan Li zhao Li Zhiji Li Tong Li Lingfeng Li Fei Li Jing Liang Jinhan Liang Zhijun Liang Guangrui Liao Hean Liao Jiajun Liao Libo Liao Longzhou Liao Yi Liao Yipu Liao Ayut Limphirat AyutLimphirat Tao Lin Weiping Lin Yufu Lin Yugen Lin Beijiang Liu Bo Liu Danning Liu Dong Liu Fu-Hu Liu Hongbang Liu Huangcheng Liu Hui Liu Huiling Liu Jia Liu Jia Liu Jiaming Liu Jianbei Liu Jianyi Liu Jingdong Liu Jinhua Liu Kai Liu Kang Liu Kun Liu Mengyao Liu Peng Liu Pengcheng Liu Qibin Liu Shan Liu Shidong Liu Shuang Liu Shubin Liu Tao Liu Tao Liu Tong Liu Wei Liu Xiang Liu Xiao-Hai Liu Xiaohui Liu Xiaoyu Liu Xin Liu Xinglin Liu Xingquan Liu Yang Liu Yanlin Liu Yao-Bei Liu Yi Liu Yiming Liu Yong Liu Yonglu Liu Yu Liu Yubin Liu Yudong Liu Yulong Liu zhaofeng Liu Zhen Liu Zhenchao Liu Zhi Liu Zhi-Feng Liu Zhiqing Liu Zhongfu Liu Zuowei Liu Mia Liu Zhen Liu Xiaoyang Liu Xinchou Lou Cai-Dian Lu Jun-Xu Lu Qiu Zhen Lu Shang Lu Shang Lu Wenxi Lu Xiaohan Lu Yunpeng Lu Zhiyong Lu Xianguo Lu Wei Lu Bayarto Lubsandorzhiev Sultim Lubsandorzhiev Arslan Lukanov Jinliang Luo Tao Luo xiaoan Luo Xiaofeng Luo Xiaolan Luo Jindong Lv Feng Lyu Xiao-Rui Lyu Kun-Feng Lyu Ande Ma Hong-Hao Ma Jun-Li Ma Kai Ma Lishuang Ma Na Ma Renjie Ma Weihu Ma Xinpeng Ma Yanling Ma Yan-Qing Ma Yongsheng Ma Zhonghui Ma Zhongjian Ma Yang Ma Mousam Maity Lining Mao Yanmin Mao Yaxian Mao Aure lien Martens Caccia Massimo Luigi Maria Shigeki Matsumoto Bruce Mellado Davide Meloni Lingling Men Cai Meng Lingxin Meng Zhenghui Mi Yuhui Miao Mauro Migliorati Lei Ming Vasiliki A.Mitsou Laura Monaco Arthur Moraes Karabo Mosala Ahmad Moursy Lichao Mu Zhihui Mu Nickolai Muchnoi Daniel Muenstermann DanielMuenstermann Pankaj Munbodh William John Murray Jerome Nanni Dmitry Nanzanov Changshan Nie Sergei Nikitin Feipeng Ning Guozhu Ning Jia-Shu Niu Juan-Juan Niu Yan Niu Edward Khomotso Nkadimeng Kazuhito Ohmi Katsunobu Oide Hideki Okawa Mohamed Ouchemhou Qun Ouyang Daniele Paesani Carlo Pagani Stathes Paganis Collette Pakuza Jiangyang Pan Juntong Pan Tong Pan Xiang Pan Papia Panda Saraswati Pandey Mila Pandurovic Rocco Paparella Roman Pasechnik Emilie Passemar r Hua Pei Xiaohua Peng Xinye Peng Yuemei Peng Jialun Ping Ronggang Ping Souvik Priyam Adhya Baohua Qi Hang Qi Huirong Qi Ming Qi Sen Qian Zhuoni Qian Congfeng Qiao Guangyou Qin Jiajia Qin Laishun Qin Liqing Qin Qin Qin Xiaoshuai Qin Zhonghua Qin 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Sun Yue Sun Zheng Sun Zheng Sun Narumon Suwonjandee Elsayed Tag Eldin Biao Tan Bo Tang Chuanxiang Tang Gao Tang Guangyi Tang Jian Tang Jingyu Tang Liang Tang Ying'Ao Tang Junquan Tao Abdel Nasser Taw fik Geoffrey Taylor Valery Telnov Saike Tian Riccardo Torre Wladyslaw Henryk Trzaska Dmitri Tsybychev Yanjun Tu Shengquan Tuo Michael Tytgat Ghalib Ul Islam Nikita Ushakov German Valencia Jaap Velthuis Alessandro Vicini Trevor Vickey Ivana Vidakovic Henri Videau Raymond Volkas Dmitry Voronin Natasa Vukasinovic Xia Wan Xuying Wan Xiao Wang Anqing Wang Bin Wang Chengtao Wang Chuanye Wang Ci Wang Dayong Wang Dou Wang En Wang Fei Wang Fei Wang Guanwen Wang Guo-Li Wang Haijing Wang Haolin Wang Jia Wang Jian Wang Jianchun Wang Jianli Wang Jiawei Wang Jin Wang Jin-Wei Wang Joseph Wang Kechen Wang Lechun Wang Lei Wang Liguo Wang Lijiao Wang Lu Wang Meng Wang Na Wang Pengcheng Wang Qian Wang Qun Wang Shu Lin Wang Shudong Wang Taofeng Wang Tianhong Wang Tianyang Wang Tong Wang Wei Wang Wei Wang Xiaolong Wang Xiaolong Wang Xiaoning Wang Xiao-Ping Wang Xiongfei Wang Xujian Wang Yaping Wang Yaqian Wang Yi Wang Yiao Wang Yifang Wang Yilun Wang Yiwei Wang You-Kai Wang Yuanping Wang Yuexin Wang Yuhao Wang Yu-Ming Wang Yuting Wang Zhen Wang Zhigang Wang Weiping Wang Zeren Simon Wang Biao Wang Hui Wang Lian-Tao Wang Zihui Wang Zirui Wang Jia Wang Tong Wang Daihui Wei Shujun Wei Wei Wei Xiaomin Wei Yuanyuan Wei Yingjie Wei Liangjian Wen Xuejun Wen Yufeng Wen Martin White Peter Williams Zef Wolffs William John Womersley Baona Wu Bobing Wu Guanjian Wu Jinfei Wu Lei Wu Lina Wu Linghui Wu Minlin Wu Peiwen Wu Qi Wu Qun Wu Tianya Wu Xiang Wu Xiaohong Wu Xing-Gang Wu Xuehui Wu Yaru Wu Yongcheng Wu Yuwen Wu Zhi Wu Xin Wu Lei Xia Ligang Xia Shang Xia Benhou Xiang Dao Xiang zhiyu Xiang Bo-Wen Xiao Chu-Wen Xiao Dong Xiao Guangyan Xiao Han Xiao Meng Xiao Ouzheng Xiao Rui-Qing Xiao Xiang Xiao Yichen Xiao Ying Xiao Yu Xiao Yunlong Xiao Zhenjun Xiao Hengyuan Xiao Nian Xie Yuehong Xie Tianmu Xin Ye Xing Zhizhong Xing Da Xu Fang Xu Fanrong Xu Haisheng Xu Haocheng Xu Ji Xu Miaofu Xu Qingjin Xu Qingnian Xu Wei Xu Wei Xu Weixi Xu Xinping Xu Zhen Xu Zijun Xu Zehua Xu Yaoyuan Xu Feifei Xue Baojun Yan Bin Yan Fen Yan Fucheng Yan Jiaming Yan Liang Yan Luping Yan Qi-Shu Yan Wenbiao Yan Yupeng Yan Luping Yan Haoyue Yan Dong Yang Fengying Yang Guicheng Yang Haijun Yang Jin Min Yang Jing Yang Lan Yang Li Yang Li Lin Yang Lili Yang Litao Yang Mei Yang Qiaoli Yang Tiansen Yang Xiaochen Yang Yingjun Yang Yueling Yang Zhengyong Yang Zhenwei Yang Youhua Yang Xiancong Yang De-Liang Yao Shi Yao Lei Ye Lingxi Ye Mei Ye Rui Ye Rui Ye Yecheng Ye Vitaly Yermolchyk Kai Yi Li Yi Yang Yi Di Yin Peng-Fei Yin Shenghua Yin Ze Yin Zhongbao Yin Zhang Yinhong Hwi Dong Yoo Zhengyun You Charles Young Boxiang Yu Chenghui Yu Fusheng Yu Jie-Sheng Yu Jinqing Yu Lingda Yu zhao-Huan Yu Felix Yu Bingrong Yu Changzheng Yuan Li Yuan Xing-Bo Yuan Youjin Yuan Junhui Yue Qian Yue Baobiao Yue Un Nisa Zaib Riccardo Zanzottera Hao Zeng Ming Zeng Jian Zhai Jiyuan Zhai Xin Zhe Zhai Xi-Jie Zhan Ben-Wei Zhang Bolun Zhang Di Zhang Guangyi Zhang Hao Zhang Hong-Hao Zhang Huaqiao Zhang Hui Zhang Jialiang Zhang Jianyu Zhang Jianzhong Zhang Jiehao Zhang Jielei Zhang Jingru Zhang Jinxian Zhang Junsong Zhang Junxing Zhang Lei Zhang Lei Zhang Liang Zhang Licheng Zhang Liming Zhang Linhao Zhang Luyan Zhang Mengchao Zhang Rao Zhang Shulei Zhang Wan Zhang Wenchao Zhang Xiangzhen Zhang Xiaomei Zhang Xiaoming Zhang Xiaoxu Zhang Xiaoyu Zhang Xuantong Zhang Xueyao Zhang Yang Zhang Yang Zhang Yanxi Zhang Yao Zhang Ying Zhang Yixiang Zhang Yizhou Zhang Yongchao Zhang Yu Zhang Yuan Zhang Yujie Zhang Yulei Zhang Yumei Zhang Yunlong Zhang Zhandong Zhang zhaoru Zhang Zhen-Hua Zhang Zhenyu Zhang Zhichao Zhang Zhi-Qing Zhang Zhuo Zhang Zhiqing Zhang Cong Zhang Tianliang Zhang Luyan Zhang Guang zhao Hongyun zhao Jie zhao Jingxia zhao Jingyi zhao Ling zhao Luyang zhao Mei zhao Minggang zhao Mingrui zhao Qiang zhao Ruiguang zhao Tongxian zhao Yaliang zhao Ying zhao Yue zhao zhiyu zhao Zhuo zhao Alexey Zhemchugov Hongjuan Zheng Jinchao Zheng Liang Zheng Ran Zheng shanxi zheng Xu-Chang Zheng Wang Zhile Weicai Zhong Yi-Ming Zhong Chen Zhou Daicui Zhou Jianxin Zhou Jing Zhou Jing Zhou Ning Zhou Qi-Dong Zhou Shiyu Zhou Shun Zhou Sihong Zhou Xiang Zhou Xingyu Zhou Yang Zhou Yong Zhou Yu-Feng Zhou Zusheng Zhou Demin Zhou Dechong Zhu Hongbo Zhu Huaxing Zhu Jingya Zhu Kai Zhu Pengxuan Zhu Ruilin Zhu Xianglei Zhu Yingshun Zhu Yongfeng Zhu Xiao Zhuang Xuai Zhuang Mikhail Zobov Zhanguo Zong Cong Zou Hongying Zou 《Radiation Detection Technology and Methods》 CSCD 2024年第1期I0003-I0016,1-1091,共1105页
The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 3... The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international partners.The complex comprises four accelerators:a 30 GeV Linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The Linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs factory.In its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs bosons.Increasing the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of magnitude.This Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering aspects.Additionally,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection procedures.Construction is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 years.The commencement of experiments and data collection could potentially be initiated in the mid-2030s. 展开更多
关键词 initiated EXCEEDING PRECISE
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Investigation of calcium phosphate (CaP) tribofilms from commercial automatic transmission fluids (ATFs) and their correlation with antishudder performance 被引量:3
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作者 Zechao DI Jingjing XU +6 位作者 Yang LIU Yu JIANG Dongsheng HUANG Haitao CUI Zhongguo LIU zhiyu zhao Shaohui LI 《Friction》 SCIE CSCD 2020年第5期882-892,共11页
The friction properties of wet clutches are highly dependent on the surface tribofilms formed by automatic transmission fluids (ATFs). Here, four commercial ATFs were evaluated with a disc-on-disc tribometer to study ... The friction properties of wet clutches are highly dependent on the surface tribofilms formed by automatic transmission fluids (ATFs). Here, four commercial ATFs were evaluated with a disc-on-disc tribometer to study tribofilm formation on steel surfaces and the effects of tribofilms on the friction properties. The chemical composition, stoichiometry, structure, and thickness of the tribofilms were investigated by scanning electron microscopy (SEM), energy dispersive X-ray spectrometry (EDX), secondary ion mass spectrometry (SIMS), and X-ray photoelectron spectroscopy (XPS). Calcium phosphate (CaP) tribofilms form on the friction surface with all ATFs, which contributes to their antishudder characteristics. The thickness and surface coverage of CaP tribofilms are positively correlated with their antishudder properties. 展开更多
关键词 TRIBOFILM commercial ATF antishudder HYDROXYAPATITE
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Functional non-glutaraldehyde treated porcine pericardium for anti-coagulation,anti-calcification,and endothelial proliferation bioprosthetic heart valves
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作者 Xiaotong Chen Tao Yu +7 位作者 Qunshou Kong Dajun Kuang Hong Xu zhiyu zhao Li Yang Gaocan Li Haojun Fan Yunbing Wang 《Journal of Leather Science and Engineering》 2022年第1期320-332,共13页
In the last decade,the number of transcatheter heart valve replacement for severe heart valve disease has increased exponentially.Although the bioprosthetic artificial heart valve(BHV)has similar fluid dynamics perfor... In the last decade,the number of transcatheter heart valve replacement for severe heart valve disease has increased exponentially.Although the bioprosthetic artificial heart valve(BHV)has similar fluid dynamics performance to the original heart valve compared with mechanical heart valve so that there is no need to take long-term anticoagulant drugs to prevent thromboembolism,transcatheter BHV replacement are still at risk for thrombosis during the first few months according to the clinical data.However,the use of antithrombotic drugs can also increase the risk of bleeding.Therefore,it is particularly important to improve the anticoagulant properties for the BHV itself.In this work,a kind of non-glutaraldehyde cross-linked BHV material with excellent antithrombotic ability has been prepared from carboxylated oxazolidine treated porcine pericardium(consisting of collagen,elastin and glycoprotein)with the further graft of the anticoagulant heparin sodium via hydrophilic modified chitosan.Along with the similar mechanical properties and collagen stability comparable to the glutaraldehyde cross-linked porcine pericardium(PP),these functional non-glutaraldehyde cross-linked PPs exhibit better biocompatibility,promoted endothelial proliferation and superior anti-calcification ability.More importantly,excellent anticoagulant activity can be observed in the hematological experiments in vivo and in vitro.In summary,these excellent performances make these functional non-glutaraldehyde cross-linked PPs great potentialities in the BHV applications. 展开更多
关键词 Bioprosthetic heart valves Oxazolidine CYTOCOMPATIBILITY ANTI-COAGULATION
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