Focal nodular hyperplasia(FNH) is a benign hepatic tumor characterized by hepatocyte hyperplasia and a central stellate scar.The association of FNH with other hepatic lesions,such as adenomas,hemangiomas and hepatocel...Focal nodular hyperplasia(FNH) is a benign hepatic tumor characterized by hepatocyte hyperplasia and a central stellate scar.The association of FNH with other hepatic lesions,such as adenomas,hemangiomas and hepatocellular carcinoma,has been previously reported,but FNH associated with another hepatic tumor is rare in infants.Here we report a case of FNH coexistentwith hepatoblastoma in a 36-d-old girl.Computed tomography(CT) imaging showed an ill-delineated,inhomogeneous enhanced mass with a central star-like scar in the right lobe of the liver.The tumor showed early mild enhancement at the arterial phase(from 40 HU without contrast to 52 HU at the arterial phase),intense enhancement at the portal phase(87.7HU) and 98.1HU in the 3-min delay scan.A central scar in the tumor presented as low density on non-contrast CT and slightly enhanced at delayed contrast-enhanced scanning.This infant underwent surgical resection of the tumor.Histopathology demonstrated typical FNH coexistent with a focal hepatoblastoma,which showed epithelioid tumor cells separated by proliferated fibrous tissue.展开更多
To the Editor:Nowadays,most infants with tetralogy of Fallot(TOF)survive the initial surgical repair;however,they continue to experience residual hemodynamic and physiologic abnormalities in the follow-up.[1]Pulmonary...To the Editor:Nowadays,most infants with tetralogy of Fallot(TOF)survive the initial surgical repair;however,they continue to experience residual hemodynamic and physiologic abnormalities in the follow-up.[1]Pulmonary regurgitation(PR)is still recognized as the most common complication that determines late outcomes.PR may result in right ventricular(RV)dilatation and,ultimately,cardiac dysfunction.Indicators of deterioration of clinical status such as impaired exercise tolerance,ventricular arrhythmia,and sudden cardiac death have all been associated with chronic PR.展开更多
基金Supported by National Key Clinical Specialty Construction Programs of China(2014-2016)Medical Guide Project of Shanghai Municipal Science and Technology Commission,No.134119a4100(to Qiao ZW)
文摘Focal nodular hyperplasia(FNH) is a benign hepatic tumor characterized by hepatocyte hyperplasia and a central stellate scar.The association of FNH with other hepatic lesions,such as adenomas,hemangiomas and hepatocellular carcinoma,has been previously reported,but FNH associated with another hepatic tumor is rare in infants.Here we report a case of FNH coexistentwith hepatoblastoma in a 36-d-old girl.Computed tomography(CT) imaging showed an ill-delineated,inhomogeneous enhanced mass with a central star-like scar in the right lobe of the liver.The tumor showed early mild enhancement at the arterial phase(from 40 HU without contrast to 52 HU at the arterial phase),intense enhancement at the portal phase(87.7HU) and 98.1HU in the 3-min delay scan.A central scar in the tumor presented as low density on non-contrast CT and slightly enhanced at delayed contrast-enhanced scanning.This infant underwent surgical resection of the tumor.Histopathology demonstrated typical FNH coexistent with a focal hepatoblastoma,which showed epithelioid tumor cells separated by proliferated fibrous tissue.
文摘To the Editor:Nowadays,most infants with tetralogy of Fallot(TOF)survive the initial surgical repair;however,they continue to experience residual hemodynamic and physiologic abnormalities in the follow-up.[1]Pulmonary regurgitation(PR)is still recognized as the most common complication that determines late outcomes.PR may result in right ventricular(RV)dilatation and,ultimately,cardiac dysfunction.Indicators of deterioration of clinical status such as impaired exercise tolerance,ventricular arrhythmia,and sudden cardiac death have all been associated with chronic PR.
