Objective: The aim of our study was to investigate the expression of p53, p57(Kip2) and CD68 in esophageal squamous cell carcinoma (ESCC) and their correlation with the biological behavior of ESCC. Methods: The protei...Objective: The aim of our study was to investigate the expression of p53, p57(Kip2) and CD68 in esophageal squamous cell carcinoma (ESCC) and their correlation with the biological behavior of ESCC. Methods: The protein expressions of p53, p57(Kip2) and CD68 were detected in 51 cases of ESCC with S-P immunohistochemical method. Results: The total positive rate of those proteins was p53 64.71%, CD68 58.82% and p57(Kip2) 45.09% respectively in ESCC. The positive expression rate of p57(Kip2) was significantly lower in the positive p53 of ESCC than in the negative p53 (P < 0.05). The positive expression rate of p57(Kip2) was significantly lower in the positive CD68 of esophageal squamous cell carcinoma than in the negative (P < 0.05). The positive expression of p53 and CD68 were related to differentiate and TNM of ESCC, but p57(Kip2) was not related to TNM (P > 0.05). Conclusion: There are significant negative correlations between p57(Kip2) and p53, CD68 protein expression and related to biological behavior. Multy predictors are better guide to patients than single predictor.展开更多
Let C(n)be a complete intersection monomial curve in the 4-dimensional affine space.In this paper we study the complete intersection property of the monomial curve C(n+wv),where w>0 is an integer and v ∈ N^4.In ad...Let C(n)be a complete intersection monomial curve in the 4-dimensional affine space.In this paper we study the complete intersection property of the monomial curve C(n+wv),where w>0 is an integer and v ∈ N^4.In addition,we investigate the Cohen-Macaulayness of the tangent cone of C(n+wv).展开更多
We provide some exact formulas for the projective dimension and regularity of edge ideals associated to some vertex-weighted oriented cyclic graphs with a common vertex or edge.These formulas axe functions in the weig...We provide some exact formulas for the projective dimension and regularity of edge ideals associated to some vertex-weighted oriented cyclic graphs with a common vertex or edge.These formulas axe functions in the weight of the vertices,and the numbers of edges and cycles.Some examples show that these formulas are related to direction selection and the assumption that w(x)≥2 for any vertex x cannot be dropped.展开更多
Let S = K[x1, x2,..., xn] be the polynomial ring in n variables over a field K, and let I be a squarefree monomial ideal minimally generated by the monomials ul,u2,...,Um. Let w be the smallest number t with the prope...Let S = K[x1, x2,..., xn] be the polynomial ring in n variables over a field K, and let I be a squarefree monomial ideal minimally generated by the monomials ul,u2,...,Um. Let w be the smallest number t with the property that for all integers 1 ≤ i1 〈 i2 〈 … 〈 it ≤ m such that lcm(uil, ui2,..., uii) = lcm(ul,u2,...,Um). We give an upper bound for Castelnuovo-Mumford regularity of I by the bigsize of I. As a corollary, the projective dimension of I is bounded by the number w.展开更多
文摘Objective: The aim of our study was to investigate the expression of p53, p57(Kip2) and CD68 in esophageal squamous cell carcinoma (ESCC) and their correlation with the biological behavior of ESCC. Methods: The protein expressions of p53, p57(Kip2) and CD68 were detected in 51 cases of ESCC with S-P immunohistochemical method. Results: The total positive rate of those proteins was p53 64.71%, CD68 58.82% and p57(Kip2) 45.09% respectively in ESCC. The positive expression rate of p57(Kip2) was significantly lower in the positive p53 of ESCC than in the negative p53 (P < 0.05). The positive expression rate of p57(Kip2) was significantly lower in the positive CD68 of esophageal squamous cell carcinoma than in the negative (P < 0.05). The positive expression of p53 and CD68 were related to differentiate and TNM of ESCC, but p57(Kip2) was not related to TNM (P > 0.05). Conclusion: There are significant negative correlations between p57(Kip2) and p53, CD68 protein expression and related to biological behavior. Multy predictors are better guide to patients than single predictor.
文摘Let C(n)be a complete intersection monomial curve in the 4-dimensional affine space.In this paper we study the complete intersection property of the monomial curve C(n+wv),where w>0 is an integer and v ∈ N^4.In addition,we investigate the Cohen-Macaulayness of the tangent cone of C(n+wv).
基金supported by the National Natural Science Foundation of China(No.11271275)the Foundation of the Priority Academic Program Development of Jiangsu Higher Education Institutions。
文摘We provide some exact formulas for the projective dimension and regularity of edge ideals associated to some vertex-weighted oriented cyclic graphs with a common vertex or edge.These formulas axe functions in the weight of the vertices,and the numbers of edges and cycles.Some examples show that these formulas are related to direction selection and the assumption that w(x)≥2 for any vertex x cannot be dropped.
基金This work was supported in part by the National Natural Science Foundation of China (Grant No. 11201326), the Natural Science Foundation of Jiangsu Province (No. BK2011276), and the Jiangsu Provincial Training Programs of Innovation and Entrepreneurship for Undergraduates.
文摘Let S = K[x1, x2,..., xn] be the polynomial ring in n variables over a field K, and let I be a squarefree monomial ideal minimally generated by the monomials ul,u2,...,Um. Let w be the smallest number t with the property that for all integers 1 ≤ i1 〈 i2 〈 … 〈 it ≤ m such that lcm(uil, ui2,..., uii) = lcm(ul,u2,...,Um). We give an upper bound for Castelnuovo-Mumford regularity of I by the bigsize of I. As a corollary, the projective dimension of I is bounded by the number w.