Self-aggregation and sluggish transport kinetics of cathode materials would usually lead to the poor electrochemical performance for aqueous zinc-ion batteries(AZIBs).In this work,we report the construction of C@VO_(2...Self-aggregation and sluggish transport kinetics of cathode materials would usually lead to the poor electrochemical performance for aqueous zinc-ion batteries(AZIBs).In this work,we report the construction of C@VO_(2) composite via anti-aggregation growth and hierarchical porous carbon encapsulation.Both of the morphology of composite and pore structure of carbon layer can be regulated by tuning the adding amount of glucose.When acting as cathode applied for AZIBs,the C@VO_(2)-3:3 composite can deliver a high capacity of 281 m Ah g^(-1) at 0.2 A g^(-1).Moreover,such cathode also exhibits a remarkably rate capability and cyclic stability,which can release a specific capacity of 195 m Ah g^(-1) at 5 A g^(-1) with the capacity retention of 95.4%after 1000 cycles.Besides that,the evolution including the crystal structure,valence state and transport kinetics upon cycling were also deeply investigated.In conclusion,benefited from the synergistic effect of anti-aggregation morphology and hierarchical porous carbon encapsulation,the building of such C@VO_(2) composite can be highly expected to enhance the ion accessible site,boost the transport kinetics and thus performing a superior storage performance.Such design concept can be applied for other kinds of electrode materials and accelerating the development of highperformance AZIBs.展开更多
Glucagon-like peptide-1 （GLP-1） and its long-acting analogues have neuroprotective and neurotrophic properties and are emerging as potential treatments for neurodegenerative diseases. Its short half-life has limited...Glucagon-like peptide-1 （GLP-1） and its long-acting analogues have neuroprotective and neurotrophic properties and are emerging as potential treatments for neurodegenerative diseases. Its short half-life has limited the application of GLP-1 in the clinic. We generated a mutated form of human GLP-1 （mGLP-1） using site-directed mutagenesis and gene recombination techniques, and found that these modifications significantly prolonged the biological half-life of GLP-1 compared with native GLP-1 （nGLP-1）. This study investigated the role of mGLP-1 on inducing PC12 cell differentiation, mGLP-1 induced PC12 cell differentiation with neurite outgrowth and increased the expression of growth-associated protein-43 and neuronal class III I^-tubulin, and significantly increased cyclic adenosine monophosphate level. No significant difference was found between mGLP-1 and nGLP-I. The results indicate that mGLP-1 activates the GLP-1 receptor, induces PC12 cell differentiation, and has neurotrophic effects.展开更多
Background Current studies,including randomized trials and meta-analyses evaluating clinical Results of bioresorbable scaffold(BRS),have raised concerns about the first-generation device with thicker struts and limite...Background Current studies,including randomized trials and meta-analyses evaluating clinical Results of bioresorbable scaffold(BRS),have raised concerns about the first-generation device with thicker struts and limited expansion capability.Newer BRS with thinner struts and improved deliverability are expected to enhance safety and efficacy profile.Bioheart(Bio-Heart,Shanghai,China)BRS is constructed from a PLLA backbone coated with a PDLLA layer eluting sirolimus.Sixmonth Results have proved preliminary safety and effectiveness of the Bioheart BRS in patients with single de novo coronary artery lesions.We sought to report serial intracoronary imaging findings at 1 year.展开更多
Vehicle to grid technology allows bidirectional energy exchange between electric vehicles and the power grid for achieving many known benefits. However, V2G networks suffer from certain security threats, such as EV’s...Vehicle to grid technology allows bidirectional energy exchange between electric vehicles and the power grid for achieving many known benefits. However, V2G networks suffer from certain security threats, such as EV’s privacy and authentication problem. In this paper, we propose an anonymous group authentication scheme for V2G communications. This scheme realizes dynamic joining and revocation of EVs, and greatly reduces the overhead of EV revocation. Through the theoretical analysis, this scheme can ensure identity privacy of EV user and security of data transmission in the process of charging and discharging.展开更多
The deployment of smart metering provides an immense amount of data for power grid operators and energy providers. By using this data, a more efficient and flexible power grid can be realized. However, this data also ...The deployment of smart metering provides an immense amount of data for power grid operators and energy providers. By using this data, a more efficient and flexible power grid can be realized. However, this data also raises privacy concerns since it contains very sensitive information about customers. In this paper, we present a security and privacy-preserving metering scheme for the community customers, by utilizing the password authenticated key exchange (PAKE) protocol and Elliptic Curve Cryptosystem (ECC). The proposed scheme will protect the community network from possible malicious behavior, and security analysis is also given in the paper.展开更多
基金financially supported by the National Natural Science Foundation of China(Nos.51774203)the Shenzhen Science and Technology Program(Nos.JCYJ20200109105801725)。
文摘Self-aggregation and sluggish transport kinetics of cathode materials would usually lead to the poor electrochemical performance for aqueous zinc-ion batteries(AZIBs).In this work,we report the construction of C@VO_(2) composite via anti-aggregation growth and hierarchical porous carbon encapsulation.Both of the morphology of composite and pore structure of carbon layer can be regulated by tuning the adding amount of glucose.When acting as cathode applied for AZIBs,the C@VO_(2)-3:3 composite can deliver a high capacity of 281 m Ah g^(-1) at 0.2 A g^(-1).Moreover,such cathode also exhibits a remarkably rate capability and cyclic stability,which can release a specific capacity of 195 m Ah g^(-1) at 5 A g^(-1) with the capacity retention of 95.4%after 1000 cycles.Besides that,the evolution including the crystal structure,valence state and transport kinetics upon cycling were also deeply investigated.In conclusion,benefited from the synergistic effect of anti-aggregation morphology and hierarchical porous carbon encapsulation,the building of such C@VO_(2) composite can be highly expected to enhance the ion accessible site,boost the transport kinetics and thus performing a superior storage performance.Such design concept can be applied for other kinds of electrode materials and accelerating the development of highperformance AZIBs.
基金the National Natural Science Foundation of China,No.81070876the Shanghai Science and Technology Commission,No.10JC1411200the Fundamental Research Funds for the Central Universities
文摘Glucagon-like peptide-1 （GLP-1） and its long-acting analogues have neuroprotective and neurotrophic properties and are emerging as potential treatments for neurodegenerative diseases. Its short half-life has limited the application of GLP-1 in the clinic. We generated a mutated form of human GLP-1 （mGLP-1） using site-directed mutagenesis and gene recombination techniques, and found that these modifications significantly prolonged the biological half-life of GLP-1 compared with native GLP-1 （nGLP-1）. This study investigated the role of mGLP-1 on inducing PC12 cell differentiation, mGLP-1 induced PC12 cell differentiation with neurite outgrowth and increased the expression of growth-associated protein-43 and neuronal class III I^-tubulin, and significantly increased cyclic adenosine monophosphate level. No significant difference was found between mGLP-1 and nGLP-I. The results indicate that mGLP-1 activates the GLP-1 receptor, induces PC12 cell differentiation, and has neurotrophic effects.
文摘Background Current studies,including randomized trials and meta-analyses evaluating clinical Results of bioresorbable scaffold(BRS),have raised concerns about the first-generation device with thicker struts and limited expansion capability.Newer BRS with thinner struts and improved deliverability are expected to enhance safety and efficacy profile.Bioheart(Bio-Heart,Shanghai,China)BRS is constructed from a PLLA backbone coated with a PDLLA layer eluting sirolimus.Sixmonth Results have proved preliminary safety and effectiveness of the Bioheart BRS in patients with single de novo coronary artery lesions.We sought to report serial intracoronary imaging findings at 1 year.
文摘Vehicle to grid technology allows bidirectional energy exchange between electric vehicles and the power grid for achieving many known benefits. However, V2G networks suffer from certain security threats, such as EV’s privacy and authentication problem. In this paper, we propose an anonymous group authentication scheme for V2G communications. This scheme realizes dynamic joining and revocation of EVs, and greatly reduces the overhead of EV revocation. Through the theoretical analysis, this scheme can ensure identity privacy of EV user and security of data transmission in the process of charging and discharging.
文摘The deployment of smart metering provides an immense amount of data for power grid operators and energy providers. By using this data, a more efficient and flexible power grid can be realized. However, this data also raises privacy concerns since it contains very sensitive information about customers. In this paper, we present a security and privacy-preserving metering scheme for the community customers, by utilizing the password authenticated key exchange (PAKE) protocol and Elliptic Curve Cryptosystem (ECC). The proposed scheme will protect the community network from possible malicious behavior, and security analysis is also given in the paper.
