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Clinical development of tumor necrosis factor-alpha inhibitors for ankylosing spondylitis 被引量:7
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作者 zhou linguang Jiang Bin 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2018年第1期59-63,共5页
There is no radical cure for ankylosing spondylitis,a chronic inflammation in joint,till now.Tumor necrosis factor-alpha(TNF-α) inhibitors can block the cascade in inflammatory chain and improve clinical symptom.Am... There is no radical cure for ankylosing spondylitis,a chronic inflammation in joint,till now.Tumor necrosis factor-alpha(TNF-α) inhibitors can block the cascade in inflammatory chain and improve clinical symptom.Among these biological agents,three of them are marketed in China:etanercept,infliximab and adalimumab.Some of the research progresses between 2014 and 2016 are summarized including treatment application,side effects of drugs,and comprehensive research of TNF-α inhibitors. 展开更多
关键词 Ankylosing spondylitis TNF-Α ETANERCEPT INFLIXIMAB ADALIMUMAB
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