We conducted a trial to assess the influence of closure or nonclosure of the peritoneum and subcutaneous tissue on the clinical outcomes of cervical cancer patients who underwent radical hysterectomy with lower abdom-i...We conducted a trial to assess the influence of closure or nonclosure of the peritoneum and subcutaneous tissue on the clinical outcomes of cervical cancer patients who underwent radical hysterectomy with lower abdom-inal cross incision.This randomized controlled trial was performed on 158 cervical cancer patients in our hospital between January 2002 and June 2004.Eighty-two patients were allocated to the“closure”group and 76 patients to the“nonclosure”group.Results showed that non-closure of the peritoneum and subcutaneous tissue could shorten operation time and febrile duration,reduce antibiotics requirement,increase the volume of drainage and decrease the incidence of liquefaction of subcutaneous fat(P<0.05).There was no difference in blood loss,postoperative complications,bowel function restoration and post-operative stay between the two groups(P>0.05).Our study revealed that closure of the peritoneum and subcutaneous tissue provides no immedi-ate postoperative benefits while unnecessarily lengthening surgical time and anesthesia exposure.The practice of closure of the peritoneum and subcutaneous tissue at radical hysterectomy should be questioned.展开更多
文摘We conducted a trial to assess the influence of closure or nonclosure of the peritoneum and subcutaneous tissue on the clinical outcomes of cervical cancer patients who underwent radical hysterectomy with lower abdom-inal cross incision.This randomized controlled trial was performed on 158 cervical cancer patients in our hospital between January 2002 and June 2004.Eighty-two patients were allocated to the“closure”group and 76 patients to the“nonclosure”group.Results showed that non-closure of the peritoneum and subcutaneous tissue could shorten operation time and febrile duration,reduce antibiotics requirement,increase the volume of drainage and decrease the incidence of liquefaction of subcutaneous fat(P<0.05).There was no difference in blood loss,postoperative complications,bowel function restoration and post-operative stay between the two groups(P>0.05).Our study revealed that closure of the peritoneum and subcutaneous tissue provides no immedi-ate postoperative benefits while unnecessarily lengthening surgical time and anesthesia exposure.The practice of closure of the peritoneum and subcutaneous tissue at radical hysterectomy should be questioned.
