To the Editor:Due to the immunogenicity of the platelet antigens,especially blood group antigen(such as ABO antigens),human leukocyte antigen(HLA),human platelet antigen(HPA),and CD36(platelet glycoproteins IV),which ...To the Editor:Due to the immunogenicity of the platelet antigens,especially blood group antigen(such as ABO antigens),human leukocyte antigen(HLA),human platelet antigen(HPA),and CD36(platelet glycoproteins IV),which can produce corresponding alloantibodies through immune factors such as blood transfusion,pregnancy,and drugs,the immune reaction of the platelet antigens and antibodies in patients will lead to various types of alloimmune thrombocytopenia.展开更多
基金This study was supported by grants from the Major Program of Nanning Scientific Research and Technological Development Plan Project,China(grant no.20173117)the Guangxi Scientific Research and Technological Development Plan Project,China(grant no.08160-06)the Guangxi Natural Science Foundation,China(grant nos.2016GXNSFAA380143 and 2013 GXNSFBA019206).
文摘To the Editor:Due to the immunogenicity of the platelet antigens,especially blood group antigen(such as ABO antigens),human leukocyte antigen(HLA),human platelet antigen(HPA),and CD36(platelet glycoproteins IV),which can produce corresponding alloantibodies through immune factors such as blood transfusion,pregnancy,and drugs,the immune reaction of the platelet antigens and antibodies in patients will lead to various types of alloimmune thrombocytopenia.