目的:对比分析两种髋关节镜技术治疗股骨髋臼撞击征(femoroacetabular impingement,FAI)的临床疗效和并发症。方法:回顾性分析2016年6月至2019年6月采用髋关节镜手术治疗并获得随访的48例FAI患者。根据手术方式的不同分为两组,Inside-ou...目的:对比分析两种髋关节镜技术治疗股骨髋臼撞击征(femoroacetabular impingement,FAI)的临床疗效和并发症。方法:回顾性分析2016年6月至2019年6月采用髋关节镜手术治疗并获得随访的48例FAI患者。根据手术方式的不同分为两组,Inside-out组,由中央到外周;Outside-in组,由外周到中央。Inside-out组24例,男14例,女10例,年龄(39.8±7.6)岁;Outside-in组24例,男13例,女11例,年龄(39.5±9.1)岁。两组患者年龄、性别、体质量指数、侧别、撞击类型、病程、随访时间比较差异无统计学意义。对两组术后髋关节改良Harris(modified Harris hip score,mHHS),非骨关节炎髋关节(nonarthritic hip score,NAHS)评分和术后并发症发生率进行比较。结果:两组患者术后髋关节功能评分mHHS和NAHS评分均较术前提高,但组间比较差异无统计学意义(P>0.05)。Inside-out组术后4例出现神经牵拉伤,3例医源性损伤;而Outside-in组仅1例神经牵拉伤。Inside-out组并发症发生率高于Outside-in组(16.7%vs 4.2%,χ^(2)=5.400,P=0.020)。结论:Inside-out和Outside-in两种髋关节镜技术治疗FAI均可取得良好的临床效果,但相对于Inside-out技术,Outside-in技术术后并发症发生率低,针对符合适应证的患者可以优先选择。展开更多
Tetrabromoalkylthiacalix[4]arenes（1a and 1b） reacted with excess bis（tetraethylammonium）-bis（1,3- dithiole-2-thione-4,5-dithiol）zincate（2） to give thiacalix[4]arene-thiones（3a and 3b） in the presence of Na2S...Tetrabromoalkylthiacalix[4]arenes（1a and 1b） reacted with excess bis（tetraethylammonium）-bis（1,3- dithiole-2-thione-4,5-dithiol）zincate（2） to give thiacalix[4]arene-thiones（3a and 3b） in the presence of Na2S. Two novel bistetrathiafulvalene-attached thiacalix[4]arene assemblies（5a and 5b） formed via triethyl phosphite-mediated cross-coupling of thiacalix[4]arene-thiones（3a and 3b） and 4,5-biscyanoethylthio-1,3-dithiole-2-one（4）. All the four new compounds were characterized by 1H NMR, 13C NMR, IR, MS spectra and elemental analysis. Meanwhile, the structures of thiacalix[4]arene-thiones（3a and 3b） were identified by X-ray analysis. In addition, the cyclic voltammograms of the resulting thiacalix[4]arenes containing electroactive TTF units（5a and 5b） were provided.展开更多
Tomato(Solanum lycopersicum L.)is a thermophilic vegetable crop,but sensitive to high temperature stress,especially under the greenhouse conditions.Due to global climate changes,heat stress has now become a great thre...Tomato(Solanum lycopersicum L.)is a thermophilic vegetable crop,but sensitive to high temperature stress,especially under the greenhouse conditions.Due to global climate changes,heat stress has now become a great threat to tomato production and fruit quality.Many studies have been conducted to determine the functions of genes in tomato responsive to abiotic and biotic stresses,but transcriptomic information on heat stress responses of tomato fruit is still limited.To investigate heat stress associated genes in tomato fruit,a cDNA library was constructed using fruit harvested from tomato cv.P19-9 plants grown under 42℃for 0,1,2 and4 h and the expression profiles of heat stress responsive genes in tomato fruit were analyzed through RNA-seq.A total of 632224558 clean high quality paired-end reads were obtained and then mapped to reference genome for RNA-seq analysis.After quality control analysis,alignment analysis and transcript assembly,a total of 55457 RNA transcripts were obtained with functional annotations.Overall,6869 differentially expressed genes(DEGs)were identified with a significant response to one or more of the three heat stress treatment times.Based on GO enrichment analysis,22 genes potentially involved in tomato thermo-tolerance were selected and validated for their expressions through qPCR.The expression profile of tomato fruit genes obtained in this study could shed light on the mechanism and gene editing breeding projects for tomato thermo-tolerance.These findings could also benefit improvement of harvest and storage of tomato in greenhouse.展开更多
Objective: To observe the clinical effects of electroacupuncture(EA) plus tuina for cervical spondylotic radiculopathy. Methods: One hundred and twenty cases with cervical spondylotic radiculopathy were divided random...Objective: To observe the clinical effects of electroacupuncture(EA) plus tuina for cervical spondylotic radiculopathy. Methods: One hundred and twenty cases with cervical spondylotic radiculopathy were divided randomly by the digital table into the observation group and control group. The patients in an observation group were treated by EA plus tuina techniques. The patients in the control group were treated by simple tuina techniques. Results: The total effective rate was 91.7% in the observation group and 78.3% in the control group. The effective rates in the two groups were statistically different(P<0.05). Conclusion: EA plus tuina therapy is better than simple tuina therapy in the treatment of cervical spondylotic radiculopathy.展开更多
文摘目的:对比分析两种髋关节镜技术治疗股骨髋臼撞击征(femoroacetabular impingement,FAI)的临床疗效和并发症。方法:回顾性分析2016年6月至2019年6月采用髋关节镜手术治疗并获得随访的48例FAI患者。根据手术方式的不同分为两组,Inside-out组,由中央到外周;Outside-in组,由外周到中央。Inside-out组24例,男14例,女10例,年龄(39.8±7.6)岁;Outside-in组24例,男13例,女11例,年龄(39.5±9.1)岁。两组患者年龄、性别、体质量指数、侧别、撞击类型、病程、随访时间比较差异无统计学意义。对两组术后髋关节改良Harris(modified Harris hip score,mHHS),非骨关节炎髋关节(nonarthritic hip score,NAHS)评分和术后并发症发生率进行比较。结果:两组患者术后髋关节功能评分mHHS和NAHS评分均较术前提高,但组间比较差异无统计学意义(P>0.05)。Inside-out组术后4例出现神经牵拉伤,3例医源性损伤;而Outside-in组仅1例神经牵拉伤。Inside-out组并发症发生率高于Outside-in组(16.7%vs 4.2%,χ^(2)=5.400,P=0.020)。结论:Inside-out和Outside-in两种髋关节镜技术治疗FAI均可取得良好的临床效果,但相对于Inside-out技术,Outside-in技术术后并发症发生率低,针对符合适应证的患者可以优先选择。
基金Supported by the National Natural Science Foundation of China(Nos.201172105, 20872058)
文摘Tetrabromoalkylthiacalix[4]arenes（1a and 1b） reacted with excess bis（tetraethylammonium）-bis（1,3- dithiole-2-thione-4,5-dithiol）zincate（2） to give thiacalix[4]arene-thiones（3a and 3b） in the presence of Na2S. Two novel bistetrathiafulvalene-attached thiacalix[4]arene assemblies（5a and 5b） formed via triethyl phosphite-mediated cross-coupling of thiacalix[4]arene-thiones（3a and 3b） and 4,5-biscyanoethylthio-1,3-dithiole-2-one（4）. All the four new compounds were characterized by 1H NMR, 13C NMR, IR, MS spectra and elemental analysis. Meanwhile, the structures of thiacalix[4]arene-thiones（3a and 3b） were identified by X-ray analysis. In addition, the cyclic voltammograms of the resulting thiacalix[4]arenes containing electroactive TTF units（5a and 5b） were provided.
文摘Tomato(Solanum lycopersicum L.)is a thermophilic vegetable crop,but sensitive to high temperature stress,especially under the greenhouse conditions.Due to global climate changes,heat stress has now become a great threat to tomato production and fruit quality.Many studies have been conducted to determine the functions of genes in tomato responsive to abiotic and biotic stresses,but transcriptomic information on heat stress responses of tomato fruit is still limited.To investigate heat stress associated genes in tomato fruit,a cDNA library was constructed using fruit harvested from tomato cv.P19-9 plants grown under 42℃for 0,1,2 and4 h and the expression profiles of heat stress responsive genes in tomato fruit were analyzed through RNA-seq.A total of 632224558 clean high quality paired-end reads were obtained and then mapped to reference genome for RNA-seq analysis.After quality control analysis,alignment analysis and transcript assembly,a total of 55457 RNA transcripts were obtained with functional annotations.Overall,6869 differentially expressed genes(DEGs)were identified with a significant response to one or more of the three heat stress treatment times.Based on GO enrichment analysis,22 genes potentially involved in tomato thermo-tolerance were selected and validated for their expressions through qPCR.The expression profile of tomato fruit genes obtained in this study could shed light on the mechanism and gene editing breeding projects for tomato thermo-tolerance.These findings could also benefit improvement of harvest and storage of tomato in greenhouse.
基金support of Project from the Major and Special Funds of Shanghai Science and Technology Commission(No.10DZ1950700)Lu’s Acupuncture Inheritance Study of Shanghai Schools of Traditional Chinese Medicine(No.201204)
文摘Objective: To observe the clinical effects of electroacupuncture(EA) plus tuina for cervical spondylotic radiculopathy. Methods: One hundred and twenty cases with cervical spondylotic radiculopathy were divided randomly by the digital table into the observation group and control group. The patients in an observation group were treated by EA plus tuina techniques. The patients in the control group were treated by simple tuina techniques. Results: The total effective rate was 91.7% in the observation group and 78.3% in the control group. The effective rates in the two groups were statistically different(P<0.05). Conclusion: EA plus tuina therapy is better than simple tuina therapy in the treatment of cervical spondylotic radiculopathy.
