With the fast-accelerating pace of life,most of the population is troubled by anxious feelings,or they even developed anxiety disorders,which affect their life qualities viciously.The current treatment is not without ...With the fast-accelerating pace of life,most of the population is troubled by anxious feelings,or they even developed anxiety disorders,which affect their life qualities viciously.The current treatment is not without drawbacks,such as exhibiting slow or acute effects only.Music therapy has shown promising outcomes in significantly reducing tension and anxiety in many studies.To explore the underlying mechanism,we recruited 12 undergraduate student volunteers from Shanghai Jiao Tong University with habits of music listening.We explored the changes in the electroencephalogram(EEG)power spectrum both during and after listening to self-select favorite music,and the relation between EEG signals and anxiety-relieving during music listening.The results showed that the power of the band in the right parietal area was significantly higher in those who were self-report able to relax during music listening compared with those who could not get relaxed.We observed power increased in the right parietal area of self-reports,not able to relax while music playing.Also,a significant difference inband power in the left frontal area and band in the right frontal area before and after music listening was observed between high anxiety group and low anxiety group.These results imply that band activity in the left frontal area is associated with the anxiety-relieving capability of anxiety,which provides evidence for further elucidating the mechanism underlying anxiety-relieving during music listening.展开更多
Considerable evidence has revealed that essential oils and their main constituents possess anti-depressant and anxiolytic properties.In the current study,we report the effect ofβ-citronellol,the main component of ros...Considerable evidence has revealed that essential oils and their main constituents possess anti-depressant and anxiolytic properties.In the current study,we report the effect ofβ-citronellol,the main component of rose essential oil,on depressive-like and anxiety-like behaviors in chronic restraint stress(CRS)mice.We found that chronic inhalation ofβ-citronellol for 14 days could increase locomotor activity in the open field test,decrease the percentage of immobility duration in the forced swimming test,and increase open arms exploration in elevated plus-maze test in CRS mice.Western blot experiment shows that chronicβ-citronellol inhalation rescues parvalbumin(PV)expression loss in the prefrontal cortex(PFC)of CRS mice.Correlation analysis reveals a strong relationship between the PV expression in PFC and the percentage of sucrose preference of the mice.These findings indicate the relationships between the PV gene expression of PFC and the effects ofβ-citronellol inhalation.展开更多
基金the National Natural Science Founda-tion of China(No.81871064),and the Cross Foundation of Arts and Science of Shanghai Jiao Tong University(No.14JCRZ01)。
文摘With the fast-accelerating pace of life,most of the population is troubled by anxious feelings,or they even developed anxiety disorders,which affect their life qualities viciously.The current treatment is not without drawbacks,such as exhibiting slow or acute effects only.Music therapy has shown promising outcomes in significantly reducing tension and anxiety in many studies.To explore the underlying mechanism,we recruited 12 undergraduate student volunteers from Shanghai Jiao Tong University with habits of music listening.We explored the changes in the electroencephalogram(EEG)power spectrum both during and after listening to self-select favorite music,and the relation between EEG signals and anxiety-relieving during music listening.The results showed that the power of the band in the right parietal area was significantly higher in those who were self-report able to relax during music listening compared with those who could not get relaxed.We observed power increased in the right parietal area of self-reports,not able to relax while music playing.Also,a significant difference inband power in the left frontal area and band in the right frontal area before and after music listening was observed between high anxiety group and low anxiety group.These results imply that band activity in the left frontal area is associated with the anxiety-relieving capability of anxiety,which provides evidence for further elucidating the mechanism underlying anxiety-relieving during music listening.
基金the National Natural Science Foundation of China(No.81871064)the Science and Technology Conmission of Shanghai Municipality(No.13DZ2260500)the Innovation Program of Shanghai Municipal Education Commission(No.2019-01-07-00-02-E00037)。
文摘Considerable evidence has revealed that essential oils and their main constituents possess anti-depressant and anxiolytic properties.In the current study,we report the effect ofβ-citronellol,the main component of rose essential oil,on depressive-like and anxiety-like behaviors in chronic restraint stress(CRS)mice.We found that chronic inhalation ofβ-citronellol for 14 days could increase locomotor activity in the open field test,decrease the percentage of immobility duration in the forced swimming test,and increase open arms exploration in elevated plus-maze test in CRS mice.Western blot experiment shows that chronicβ-citronellol inhalation rescues parvalbumin(PV)expression loss in the prefrontal cortex(PFC)of CRS mice.Correlation analysis reveals a strong relationship between the PV expression in PFC and the percentage of sucrose preference of the mice.These findings indicate the relationships between the PV gene expression of PFC and the effects ofβ-citronellol inhalation.
