To the Editor： Gastric carcinoma is a common gastrointestinal （GI） malignancy while signet ring cell carcinoma （SRCC） is a well-known poorly differentiated histological type that has a strong tendency for metasta...To the Editor： Gastric carcinoma is a common gastrointestinal （GI） malignancy while signet ring cell carcinoma （SRCC） is a well-known poorly differentiated histological type that has a strong tendency for metastasis. The dissemination of gastric carcinoma mainly presents in three patterns. The most common approach for metastasis is through the regional lymph node. Hematogenous spread is also very common and mostly occurs in the liver, lungs, bones, and adrenal gland. In addition, direct adjacent invasion, peritoneal seeding, and Krukenberg tumor are less seen but are also very important in clinic with poor prognosis. In this report, we present a case of rare colonic metastases in the form of multiple polyps from primary gastric SRCC.展开更多
文摘To the Editor： Gastric carcinoma is a common gastrointestinal （GI） malignancy while signet ring cell carcinoma （SRCC） is a well-known poorly differentiated histological type that has a strong tendency for metastasis. The dissemination of gastric carcinoma mainly presents in three patterns. The most common approach for metastasis is through the regional lymph node. Hematogenous spread is also very common and mostly occurs in the liver, lungs, bones, and adrenal gland. In addition, direct adjacent invasion, peritoneal seeding, and Krukenberg tumor are less seen but are also very important in clinic with poor prognosis. In this report, we present a case of rare colonic metastases in the form of multiple polyps from primary gastric SRCC.
