Introduction The skin barrier usually refers to the physical barrier formed by the cuticle and sebum membrane of the skin.This barrier not only protects against the onslaught of microorganisms and percutaneous penetra...Introduction The skin barrier usually refers to the physical barrier formed by the cuticle and sebum membrane of the skin.This barrier not only protects against the onslaught of microorganisms and percutaneous penetration of chemicals and allergens but also prevents the loss of nutrients and moisture from the body.Corneodesmosomes play an important role in maintaining the function of the keraphyllous skin barrier.Desmogleins,desmocollin,and corneodesmosin are examples of corneodesmosomes.展开更多
文摘Introduction The skin barrier usually refers to the physical barrier formed by the cuticle and sebum membrane of the skin.This barrier not only protects against the onslaught of microorganisms and percutaneous penetration of chemicals and allergens but also prevents the loss of nutrients and moisture from the body.Corneodesmosomes play an important role in maintaining the function of the keraphyllous skin barrier.Desmogleins,desmocollin,and corneodesmosin are examples of corneodesmosomes.