In patients with autoimmune diseases,psychological comorbidities,including anxiety,depression and cognitive dysfunction,often occur.1 Anxiety and depression in these patients not only cause a significant disease burde...In patients with autoimmune diseases,psychological comorbidities,including anxiety,depression and cognitive dysfunction,often occur.1 Anxiety and depression in these patients not only cause a significant disease burden1 but also might prevent effective treatment through the neuro-immune axis.2 The latter issue results in disease aggravation and,in turn,adversely impacts psychological and social wellbeing.Therefore,effective treatment is required to break the vicious feedforward cycle of physical–psychological interactions.展开更多
基金supported by the National Natural Science Foundation of China(No.81701042 to C.L.,Nos.81974553 and 81800187 to W.S.)the Youth Innovation Team of Shandong Provincial Department of Education(No.2019KJK002 to W.S.)the Taishan Scholars Program of Shandong Province and Bellberry-Viertel Senior Medical Research Fellowship(D.Y.).
文摘In patients with autoimmune diseases,psychological comorbidities,including anxiety,depression and cognitive dysfunction,often occur.1 Anxiety and depression in these patients not only cause a significant disease burden1 but also might prevent effective treatment through the neuro-immune axis.2 The latter issue results in disease aggravation and,in turn,adversely impacts psychological and social wellbeing.Therefore,effective treatment is required to break the vicious feedforward cycle of physical–psychological interactions.
