The quality control and hypoglycemic effect of Cinnamomi Cortex aqueous extract

Cinnamomi Cortex was a material as medicinal and edible resources and it has been demonstrated that Cinnamomi Cortex aqueous extract(CCAE)possess hypoglycemic effect,but there were no active compounds identified as quality standard of CCAE to be used in the investigate of hypoglycemic activity.Hence,in this study,the quality standard and the hypoglycemic effect of CCAE were investigated.Cinnamaldehyde and coumarin as the quality control in CCAE were analyzed by high performance liquid chromatography(HPLC)method.The results showed that the average yield of extraction was 10.06%.The concentration of coumarin was linear with peak area ranging from 0.02–1.00μg/mL(r=0.9996,n=6)and that of cinnamaldehyde also demonstrated a good linear relationship with peak area in the range of 1.05–52.50μg/mL(r=0.9997,n=6).The average recovery rate of coumarin and cinnamaldehyde was 99.42%and 100.11%,respectively.The investigation of hypoglycemic effect revealed that CCAE could improve weight loss,lower liver and pancreas indices,improve organ damage caused by diabetes,and lower fasting blood glucose,glycosylated serum protein(GSP)and total cholesterol(TC)levels.The results showed that CCAE can reduce fasting blood glucose and blood lipid levels in diabetic mice.

Identifying factors that affect environmental air quality using geographical detectors in the NKEFAs of China

The establishment of the National Key Ecological Function Areas(NKEFAs)is an important measure for national ecological security,but the current ecological and environmental evaluation of NKEFAs lacks research on the air quality in the NKEFAs.This study presented the current status of the air quality in the NKEFAs and its driving factors using the geographic detector q-statistic method.The air quality in the NKEFAs was overall better than individual cities and urban agglomeration in eastern coast provinces of China,accounting for 9.21%of the days with air quality at Level III or above.The primary air pollutant was PM_(10),followed by PM_(2.5),with lower concentrations of the remaining pollutants.Pollution was more severe in the sand fixation areas,where air pollution was worst in spring and best in autumn,contrasting with other NKEFAs and individual cities and urban agglomerations.The main influencing factors of air quality index(AQI)in the NKEFAs were land use type,wind speed,and relative humidity also weighted more heavily than factors such as industrial pollution and anthropogenic emissions,and most of these influence factors have two types of interactive effects:binary and nonlinear enhancements.These results indicated that air pollution in the NKEFAs was not related with the emission by intensive economic development.Thus,the policies taking the NKEFAs as restricted development zones were effective,but the air pollution caused by PM_(10) also showed the ecological status in the NKEFAs,especially at sand fixation areas was not quite optimistic,and more strict environmental protection measures should be taken to improve the ecological status in these NKEFAs.