A variety of micro-tweezers techniques, such as optical tweezers, magnetic tweezers, and dielectrophoresis technique, have been applied intensively in precise characterization of micro/nanoparticles and bio-molecules....A variety of micro-tweezers techniques, such as optical tweezers, magnetic tweezers, and dielectrophoresis technique, have been applied intensively in precise characterization of micro/nanoparticles and bio-molecules. They have contributed remarkably in better understanding of working mechanisms of individual sub-cell organelles, proteins, and DNA. In this paper, we present a controllable electrostatic device embedded in a microchannel, which is capable of driving,trapping, and releasing charged micro-particles suspended in microfluid, demonstrating the basic concepts of electrostatic tweezers. Such a device is scalable to smaller size and offers an alternative to currently used micro-tweezers for application in sorting, selecting, manipulating, and analyzing individual micro/nanoparticles. Furthermore, the system offers the potential in being combined with dielectrophoresis and other techniques to create hybrid micro-manipulation systems.展开更多
基金financially supported by National Natural Science Foundation of China (NSFC Grants No.11374016)MOST of China (Grant 2012CB932702, 2011CB933002)
文摘A variety of micro-tweezers techniques, such as optical tweezers, magnetic tweezers, and dielectrophoresis technique, have been applied intensively in precise characterization of micro/nanoparticles and bio-molecules. They have contributed remarkably in better understanding of working mechanisms of individual sub-cell organelles, proteins, and DNA. In this paper, we present a controllable electrostatic device embedded in a microchannel, which is capable of driving,trapping, and releasing charged micro-particles suspended in microfluid, demonstrating the basic concepts of electrostatic tweezers. Such a device is scalable to smaller size and offers an alternative to currently used micro-tweezers for application in sorting, selecting, manipulating, and analyzing individual micro/nanoparticles. Furthermore, the system offers the potential in being combined with dielectrophoresis and other techniques to create hybrid micro-manipulation systems.
