Augmented reality(AR)and virtual reality(VR)are two novel display technologies that are under updates.The essential feature of AR/VR is the full-color display that requires high pixel densities.To generate three-color...Augmented reality(AR)and virtual reality(VR)are two novel display technologies that are under updates.The essential feature of AR/VR is the full-color display that requires high pixel densities.To generate three-color pixels,the fluorescent color conversion layer inevitably includes green and red pixels.To fabricate such sort of display kits,inkjet printing is a promising way to position the color conversion layers.In this review article,the progress of AR/VR technologies is first reviewed,and in succession,the state of the art of inkjet printing,as well as two key issues-the optimization of ink and the reduction of coffee-ring effects,are introduced.Finally,some potential problems associated with the color converting layer are highlighted.展开更多
Background:Amygdala plays an important role in the neurobiological basis of panic disorder(PD),and the amygdala contains different subregions,which may play different roles in PD.The aim of the present study was to ex...Background:Amygdala plays an important role in the neurobiological basis of panic disorder(PD),and the amygdala contains different subregions,which may play different roles in PD.The aim of the present study was to examine whether there are common or distinct patterns of functional connectivity of the amygdala subregions in PD using resting-state functional magnetic resonance imaging and to explore the relationship between the abnormal spontaneous functional connectivity patterns of the regions of interest(ROIs)and the clinical symptoms of PD patients.Methods:Fifty-three drug-naïve,non-comorbid PD patients and 70 healthy controls(HCs)were recruited.Seed-based resting-state functional connectivity(rsFC)analyses were conducted using the bilateral amygdalae and its subregions as the ROI seed.Two samples t test was performed for the seed-based Fisher's z-transformed correlation maps.The relationship between the abnormal spontaneous functional connectivity patterns of the ROIs and the clinical symptoms of PD patients was investigated by Pearson correlation analysis.Results:PD patients showed increased rsFC of the bilateral amygdalae and almost all the amygdala subregions with the precuneus/posterior cingulate gyrus compared with the HC group(left amygdala[lAMY]:t=4.84,P<0.001;right amygdala[rAMY]:t=4.55,P<0.001;left centromedial amygdala[lCMA]:t=3.87,P<0.001;right centromedial amygdala[rCMA]:t=3.82,P=0.002;left laterobasal amygdala[lBLA]:t=4.33,P<0.001;right laterobasal amygdala[rBLA]:t=4.97,P<0.001;left superficial amygdala[lSFA]:t=3.26,P=0.006).The rsFC of the lBLA with the left angular gyrus/inferior parietal lobule remarkably increased in the PD group(t=3.70,P=0.003).And most of the altered rsFCs were located in the default mode network(DMN).A significant positive correlation was observed between the severity of anxiety and the rsFC between the lSFA and the left precuneus in PD patients(r=0.285,P=0.039).Conclusions:Our research suggested that the increased rsFC of amygdala subregions with DMN plays an important role in the pathogenesis of PD.Future studies may further explore whether the rsFC of amygdala subregions,especially with the regions in DMN,can be used as a biological marker of PD.展开更多
基金supported by the National Natural Science Foundation of China (11904302)the Fundamental Research Funds for the Central Universities (Grant No.20720190005)+1 种基金the Major Science and Technology Project of Xiamen in China (3502Z20191015)Hong Kong University of Science and Technology-Foshan Joint Research Program (FSUST19-FYTRI11)
文摘Augmented reality(AR)and virtual reality(VR)are two novel display technologies that are under updates.The essential feature of AR/VR is the full-color display that requires high pixel densities.To generate three-color pixels,the fluorescent color conversion layer inevitably includes green and red pixels.To fabricate such sort of display kits,inkjet printing is a promising way to position the color conversion layers.In this review article,the progress of AR/VR technologies is first reviewed,and in succession,the state of the art of inkjet printing,as well as two key issues-the optimization of ink and the reduction of coffee-ring effects,are introduced.Finally,some potential problems associated with the color converting layer are highlighted.
基金Capital’s Funds for Health Improvement and Research(No.2020-1-2121)Beijing Municipal Science and Technology Commission(No.Z181100001718077)Special Funding of the Beijing Municipal Administration of Hospitals Clinical Medicine Development(No.ZYLX201815)
文摘Background:Amygdala plays an important role in the neurobiological basis of panic disorder(PD),and the amygdala contains different subregions,which may play different roles in PD.The aim of the present study was to examine whether there are common or distinct patterns of functional connectivity of the amygdala subregions in PD using resting-state functional magnetic resonance imaging and to explore the relationship between the abnormal spontaneous functional connectivity patterns of the regions of interest(ROIs)and the clinical symptoms of PD patients.Methods:Fifty-three drug-naïve,non-comorbid PD patients and 70 healthy controls(HCs)were recruited.Seed-based resting-state functional connectivity(rsFC)analyses were conducted using the bilateral amygdalae and its subregions as the ROI seed.Two samples t test was performed for the seed-based Fisher's z-transformed correlation maps.The relationship between the abnormal spontaneous functional connectivity patterns of the ROIs and the clinical symptoms of PD patients was investigated by Pearson correlation analysis.Results:PD patients showed increased rsFC of the bilateral amygdalae and almost all the amygdala subregions with the precuneus/posterior cingulate gyrus compared with the HC group(left amygdala[lAMY]:t=4.84,P<0.001;right amygdala[rAMY]:t=4.55,P<0.001;left centromedial amygdala[lCMA]:t=3.87,P<0.001;right centromedial amygdala[rCMA]:t=3.82,P=0.002;left laterobasal amygdala[lBLA]:t=4.33,P<0.001;right laterobasal amygdala[rBLA]:t=4.97,P<0.001;left superficial amygdala[lSFA]:t=3.26,P=0.006).The rsFC of the lBLA with the left angular gyrus/inferior parietal lobule remarkably increased in the PD group(t=3.70,P=0.003).And most of the altered rsFCs were located in the default mode network(DMN).A significant positive correlation was observed between the severity of anxiety and the rsFC between the lSFA and the left precuneus in PD patients(r=0.285,P=0.039).Conclusions:Our research suggested that the increased rsFC of amygdala subregions with DMN plays an important role in the pathogenesis of PD.Future studies may further explore whether the rsFC of amygdala subregions,especially with the regions in DMN,can be used as a biological marker of PD.
