Objective: To examine the antioxidant and the antimicrobial activities of the marine seaweeds Padina pavonica (P. pavonica) and Enteromorpha sp. from the Tunisian Mediterranean coast. Methods: The acetone and water we...Objective: To examine the antioxidant and the antimicrobial activities of the marine seaweeds Padina pavonica (P. pavonica) and Enteromorpha sp. from the Tunisian Mediterranean coast. Methods: The acetone and water were used for algae extraction to envisage the antimicrobial activity versus Gram-negative (Escherichia coli and Pseudomonas aeruginosa), Gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) and against four Candida. The microdilution method was used to evaluate this activity. In vitro, total phenolic content and the antioxidant activity including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and 2,2'-azino-bis-(3-ethylbenthiazoline)-6-sulfonic acid (ABTS) were also studied. Results: The highest amount of phenolic compound was found in the P. pavonica acetonic extract ((90.61 ± 0.11) mg catechin equivalent/g extract)This brown algae sample demonstrated greater DPPH and ABTS radical scavenging ability potential in comparison to other green seaweed, Enteromorpha sp. The maximum antimicrobial activity was shown by the P. pavonica acetonic extract against all the pathogenic strains tested (minimum inhibitory concentrations = minimum inhibitory bactericidal = minimum inhibitory fungicidal concentrations = 0.04 mg/mL). Those activities might be due to phenolic substances present in this fraction. Conclusions: The present results highlight the possible use of P. pavonica as source of antioxidant and antimicrobial compounds.展开更多
文摘Objective: To examine the antioxidant and the antimicrobial activities of the marine seaweeds Padina pavonica (P. pavonica) and Enteromorpha sp. from the Tunisian Mediterranean coast. Methods: The acetone and water were used for algae extraction to envisage the antimicrobial activity versus Gram-negative (Escherichia coli and Pseudomonas aeruginosa), Gram-positive bacteria (Staphylococcus aureus and Enterococcus faecalis) and against four Candida. The microdilution method was used to evaluate this activity. In vitro, total phenolic content and the antioxidant activity including 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging and 2,2'-azino-bis-(3-ethylbenthiazoline)-6-sulfonic acid (ABTS) were also studied. Results: The highest amount of phenolic compound was found in the P. pavonica acetonic extract ((90.61 ± 0.11) mg catechin equivalent/g extract)This brown algae sample demonstrated greater DPPH and ABTS radical scavenging ability potential in comparison to other green seaweed, Enteromorpha sp. The maximum antimicrobial activity was shown by the P. pavonica acetonic extract against all the pathogenic strains tested (minimum inhibitory concentrations = minimum inhibitory bactericidal = minimum inhibitory fungicidal concentrations = 0.04 mg/mL). Those activities might be due to phenolic substances present in this fraction. Conclusions: The present results highlight the possible use of P. pavonica as source of antioxidant and antimicrobial compounds.