Background & Aims: The epidemiology of fecal incontinence (FI) is incompletely understood. We report the pre- valence, clinical spectrum, health care- seeking behavior, and quality of life (QOL) in community women...Background & Aims: The epidemiology of fecal incontinence (FI) is incompletely understood. We report the pre- valence, clinical spectrum, health care- seeking behavior, and quality of life (QOL) in community women with FI. Methods: A questionnaire was mailed to an age- stratified random sample of 5300 Olmsted County, Minnesota, women identified by the Rochester Epidemiology Project. Symptom severity was assessed by a validated scale, and impact on QOL was evaluated for subjects who had any FI during the past year. The prevalence of FI was calculated with direct age adjustment to the 2000 US white female population. Results: Altogether, 2800 of 5300 women (53% ) responded to the survey. The overall age- adjusted prevalence of FI in the past year was 12.1 per 100 (95% confidence interval, 11.0- 13.1). The prevalence increased with age from 7 (third decade) to 22 (sixth decade) per 100 and was steady thereafter. Symptoms were mild (45% ), moderate (50% ), or severe (5% ), and symptom severity was related to the impact of FI on QOL and physician- consulting behavior. Moderate to severe impact on < 1 domain of QOL was reported by 6% with mild, 35% with moderate, and 82% with severe symptoms, whereas 5% with mild, 10% with moderate, and 48% with severe FI had consulted a physician for FI in the past year. Conclusions: More than 1 of 10 adult women in the population have FI; almost 1 of 15 have moderate to severe FI. FI significantly impacts QOL and prompts health care utilization predominantly in women with moderate to severe symptoms.展开更多
Objectives: Validated, noninvasive studies were used to compare sensation and motor function of the upper gastrointestinal tract in adolescents with function al dyspepsia (FD) and in control subjects. Study design: Fi...Objectives: Validated, noninvasive studies were used to compare sensation and motor function of the upper gastrointestinal tract in adolescents with function al dyspepsia (FD) and in control subjects. Study design: Fifteen adolescents with FD and 15 healthy participants underwent standardized symptom assessment, a sa tiation nutrient drink test, and 13C- Spirulina platensis breath test for gastr ic emptying of solids. Adolescents with FD also underwent measurements of fastin g and postprandial gastric volume by means of single- photon emission computed tomography, and their results were compared with those from 15 healthy volunteer s (age, 18 to 25 years). Results: Compared with control subjects, adolescents wi th FD had significantly higher postprandial symptoms 30 minutes after reaching m aximum satiation with the nutrient drink test and significant delay in the T1/2 for gastric emptying of solids. Compared with healthy 18- to 25- year- old ad ults, adolescents had a diminished postprandial gastric volume response. By mean s of single- photon emission computed tomography, frequent baseline dyspeptic s ymptoms were associated with prolonged T1/2 for gastric emptying and higher post prandial aggregate symptom score. A baseline increased severity of dyspepsia sym ptoms was associated with prolonged T1/2 for gastric emptying. Conclusions: Adol escents with FD demonstrate increased postprandial symptoms after challenge,dela yed gastric emptying, and a reduced gastric volume response to feeding.展开更多
文摘Background & Aims: The epidemiology of fecal incontinence (FI) is incompletely understood. We report the pre- valence, clinical spectrum, health care- seeking behavior, and quality of life (QOL) in community women with FI. Methods: A questionnaire was mailed to an age- stratified random sample of 5300 Olmsted County, Minnesota, women identified by the Rochester Epidemiology Project. Symptom severity was assessed by a validated scale, and impact on QOL was evaluated for subjects who had any FI during the past year. The prevalence of FI was calculated with direct age adjustment to the 2000 US white female population. Results: Altogether, 2800 of 5300 women (53% ) responded to the survey. The overall age- adjusted prevalence of FI in the past year was 12.1 per 100 (95% confidence interval, 11.0- 13.1). The prevalence increased with age from 7 (third decade) to 22 (sixth decade) per 100 and was steady thereafter. Symptoms were mild (45% ), moderate (50% ), or severe (5% ), and symptom severity was related to the impact of FI on QOL and physician- consulting behavior. Moderate to severe impact on < 1 domain of QOL was reported by 6% with mild, 35% with moderate, and 82% with severe symptoms, whereas 5% with mild, 10% with moderate, and 48% with severe FI had consulted a physician for FI in the past year. Conclusions: More than 1 of 10 adult women in the population have FI; almost 1 of 15 have moderate to severe FI. FI significantly impacts QOL and prompts health care utilization predominantly in women with moderate to severe symptoms.
文摘Objectives: Validated, noninvasive studies were used to compare sensation and motor function of the upper gastrointestinal tract in adolescents with function al dyspepsia (FD) and in control subjects. Study design: Fifteen adolescents with FD and 15 healthy participants underwent standardized symptom assessment, a sa tiation nutrient drink test, and 13C- Spirulina platensis breath test for gastr ic emptying of solids. Adolescents with FD also underwent measurements of fastin g and postprandial gastric volume by means of single- photon emission computed tomography, and their results were compared with those from 15 healthy volunteer s (age, 18 to 25 years). Results: Compared with control subjects, adolescents wi th FD had significantly higher postprandial symptoms 30 minutes after reaching m aximum satiation with the nutrient drink test and significant delay in the T1/2 for gastric emptying of solids. Compared with healthy 18- to 25- year- old ad ults, adolescents had a diminished postprandial gastric volume response. By mean s of single- photon emission computed tomography, frequent baseline dyspeptic s ymptoms were associated with prolonged T1/2 for gastric emptying and higher post prandial aggregate symptom score. A baseline increased severity of dyspepsia sym ptoms was associated with prolonged T1/2 for gastric emptying. Conclusions: Adol escents with FD demonstrate increased postprandial symptoms after challenge,dela yed gastric emptying, and a reduced gastric volume response to feeding.
