目的:阿尔茨海默病(Alzheimer’s disease,AD)是全球最常见的引起老年人痴呆的疾病,AD与睡眠障碍存在着密切的关系,AD患者常常伴随着睡眠障碍,而睡眠障碍又可能加重AD症状,甚至加速疾病发展。方法:检索Web of Science核心合集数据库中19...目的:阿尔茨海默病(Alzheimer’s disease,AD)是全球最常见的引起老年人痴呆的疾病,AD与睡眠障碍存在着密切的关系,AD患者常常伴随着睡眠障碍,而睡眠障碍又可能加重AD症状,甚至加速疾病发展。方法:检索Web of Science核心合集数据库中1999~2022年关于“睡眠障碍”和“阿尔茨海默病”的关键词,发表类型仅限于英文“article”,使用citespace软件对国家、机构、期刊、作者、关键词和文献等进行了可视化分析。结果:根据纳入标准,最终纳入1118篇文献。AD患者睡眠障碍研究文献数量呈上升趋势,《JOURNAL OF ALZHEIMERS DISEASE》发表了最多的相关论文,美国处于这项研究的前沿,发表的论文数量最多,宾夕法尼亚大学是发文量最多的机构。此外,AD合并睡眠障碍的机制是该领域专家们高度关注和研究的重要方向,睡眠-觉醒周期、快速眼动睡眠和慢波睡眠与β-淀粉样蛋白和tau蛋白水平的关系备受关注。结论:AD与睡眠障碍关系密切。本文为学者选择研究方向提供了有价值的参考,有助于推动阿尔茨海默睡眠障碍的研究进展。展开更多
Electricity from clean and renewable resources is a promising solution to address the growing energy crisis.Water,an abundant and widely distributed substance on the planet,contains tremendous energy[1,2].Recently,it ...Electricity from clean and renewable resources is a promising solution to address the growing energy crisis.Water,an abundant and widely distributed substance on the planet,contains tremendous energy[1,2].Recently,it was demonstrated that electricity can be generated directly through the interaction between water and nanostructured materials,termed as the hydrovoltaic effect[3],facilitating energy harvesting from water.In particular,it was found that the natural evaporation of water can sustainably generate an electric voltage of up to 1 V across a carbon black film[4].展开更多
文摘目的:阿尔茨海默病(Alzheimer’s disease,AD)是全球最常见的引起老年人痴呆的疾病,AD与睡眠障碍存在着密切的关系,AD患者常常伴随着睡眠障碍,而睡眠障碍又可能加重AD症状,甚至加速疾病发展。方法:检索Web of Science核心合集数据库中1999~2022年关于“睡眠障碍”和“阿尔茨海默病”的关键词,发表类型仅限于英文“article”,使用citespace软件对国家、机构、期刊、作者、关键词和文献等进行了可视化分析。结果:根据纳入标准,最终纳入1118篇文献。AD患者睡眠障碍研究文献数量呈上升趋势,《JOURNAL OF ALZHEIMERS DISEASE》发表了最多的相关论文,美国处于这项研究的前沿,发表的论文数量最多,宾夕法尼亚大学是发文量最多的机构。此外,AD合并睡眠障碍的机制是该领域专家们高度关注和研究的重要方向,睡眠-觉醒周期、快速眼动睡眠和慢波睡眠与β-淀粉样蛋白和tau蛋白水平的关系备受关注。结论:AD与睡眠障碍关系密切。本文为学者选择研究方向提供了有价值的参考,有助于推动阿尔茨海默睡眠障碍的研究进展。
基金financially supported by the National Key Research and Development Program of China(2019YFA0705900)funded by the Ministry of Science and Technology(MOST)the National Natural Science Foundation of China(52073281,22135007 and 21875244)the Natural Science Foundation of Jilin Province(20230101122JC)。
基金supported by the National Key Research and Development Program of China (2019YFA0705400)the National Natural Science Foundation of China (12150002, 12172176, 12002158,52002175, and 11802121)+4 种基金the Natural Science Foundation of Jiangsu Province (BK20212008 and BK20211191)the Research Fund of State Key Laboratory of Mechanics and Control of Mechanical Structures (MCMS-I-0421G01 and MCMS-I-0421K01)China Postdoctoral Science Foundation(2018T110494, 2020TQ0146, and 2021M701703)the Fundamental Research Funds for the Central Universities (NE2020001, NJ2020003, NZ2020001, and NS2021042)a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions。
文摘Electricity from clean and renewable resources is a promising solution to address the growing energy crisis.Water,an abundant and widely distributed substance on the planet,contains tremendous energy[1,2].Recently,it was demonstrated that electricity can be generated directly through the interaction between water and nanostructured materials,termed as the hydrovoltaic effect[3],facilitating energy harvesting from water.In particular,it was found that the natural evaporation of water can sustainably generate an electric voltage of up to 1 V across a carbon black film[4].