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Berbamine inhibits SARS-CoV-2 infection by compromising TRPMLs-mediated endolysosomal trafficking of ACE2 被引量:2
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作者 Lihong Huang Terrence Tsz-Tai Yuen +4 位作者 zuodong ye Shuyan Liu Guoliang Zhang Hin Chu Jianbo Yue 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第5期1433-1435,共3页
Dear Editor,Middle East respiratory syndrome-related coronavirus(MERS-CoV)is the pathogen responsible for the outbreak of MERS,and we are currently being affected by coronavirus disease 2019(COVID-19)due to infection ... Dear Editor,Middle East respiratory syndrome-related coronavirus(MERS-CoV)is the pathogen responsible for the outbreak of MERS,and we are currently being affected by coronavirus disease 2019(COVID-19)due to infection by the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).The S protein of SARS-CoV-2 or MERS-CoV binds angiotensin-converting enzyme 2(ACE2)or dipeptidyl peptidase-4(DPP4),respectively,to facilitate viral particles entry into cells1.The COVID-19 pandemic has caused major socioeconomic disruptions globally. 展开更多
关键词 ACE2 INFECTION RESPIRATORY
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