Dear Editor,Circadian rhythms are the periodic turmover of biological behaviors and physiological functions of many organisms(Allada and Bass,2021).In mammals,circadian rhythms are maintained by the clock system,invol...Dear Editor,Circadian rhythms are the periodic turmover of biological behaviors and physiological functions of many organisms(Allada and Bass,2021).In mammals,circadian rhythms are maintained by the clock system,involving central clock in suprachiasmatic nucleus and peripheral clock in organs like intestine;and at cellular level a cell-autonomous transcriptional and translational feedback loop involving clock genes like BMAL1(brain and muscle ARNT-Like 1,also known as ARNTL),CLOCK(clock circadian regulator),PER1/2/3(period circadian regulator 1/2/3)and CRY1/2(cryptochrome circadian regulator 1/2)(Allada and Bass,2021).展开更多
基金supported by the National Key Research and Development Program of China(2018YFC2000500)the National Natural Science Foundation of China(91857101)+2 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29020000)the National Natural Science Foundation of China(81922027,81870228,and 81921006)Beijing Natural Science Foundation(Q20031)and the State Key Laboratory of Membrane Biology.
文摘Dear Editor,Circadian rhythms are the periodic turmover of biological behaviors and physiological functions of many organisms(Allada and Bass,2021).In mammals,circadian rhythms are maintained by the clock system,involving central clock in suprachiasmatic nucleus and peripheral clock in organs like intestine;and at cellular level a cell-autonomous transcriptional and translational feedback loop involving clock genes like BMAL1(brain and muscle ARNT-Like 1,also known as ARNTL),CLOCK(clock circadian regulator),PER1/2/3(period circadian regulator 1/2/3)and CRY1/2(cryptochrome circadian regulator 1/2)(Allada and Bass,2021).
