Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has man...Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has many poten- tial applications in human medicine, with the advantage of having few side effects (Keen, 2012). Investigating the mechanisms of bacteria-killing phages will therefore aid in the development of antibacterial drugs.展开更多
基金supported by the National Nature Scientific Foundation of China(No.61301260)the Applied Basic Research Program of Sichuan Province(No.2015JY0100 and LZ-LY-45)+3 种基金the Scientific Research Foundation of the Education Department of Sichuan Province(11ZB122)the Nature Scientific Foundation of Hebei Province(No.C2013209105)the Fundamental Research Funds for the Central Universities of China(No.ZYGX2015J144,ZYGX2015Z006)Program for the Top Young Innovative Talents of Higher Learning Institutions of Hebei Province(No.BJ2014028)
文摘Bacteriophages are viruses that attack bacteria and kill them through the lytic replication cycle. Many studies have reported that phages are more specific to bacteria than antibiotics are; thus, phage therapy has many poten- tial applications in human medicine, with the advantage of having few side effects (Keen, 2012). Investigating the mechanisms of bacteria-killing phages will therefore aid in the development of antibacterial drugs.