Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to Ma...Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.展开更多
With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular network...With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network.展开更多
In the 5th generation(5G)wireless communication networks,network slicing emerges where network operators(NPs)form isolated logical slices by the same cellular network infrastructure and spectrum resource.In coverage r...In the 5th generation(5G)wireless communication networks,network slicing emerges where network operators(NPs)form isolated logical slices by the same cellular network infrastructure and spectrum resource.In coverage regions of access points(APs)shared by slices,device to device(D2D)communication can occur among different slices,i.e.,one device acts as D2D relay for another device serving by a different slice,which is defined as slice cooperation in this paper.Since selfish slices will not help other slices by cooperation voluntarily and unconditionally,this paper designs a novel resource allocation scheme to stimulate slice cooperation.The main idea is to encourage slice to perform cooperation for other slices by rewarding it with higher throughput.The proposed incentive scheme for slice cooperation is formulated by an optimal problem,where cooperative activities are introduced to the objective function.Since optimal solutions of the formulated problem are long term statistics,though can be obtained,a practical online slice scheduling algorithm is designed,which can obtain optimal solutions of the formulated maximal problem.Lastly,the throughput isolation indexes are defined to evaluate isolation performance of slice.According to simulation results,the proposed incentive scheme for slice cooperation can stimulate slice cooperation effectively,and the isolation of slice is also simulated and discussed.展开更多
The centralized radio access cellular network infrastructure based on centralized Super Base Station(CSBS) is a promising solution to reduce the high construction cost and energy consumption of conventional cellular n...The centralized radio access cellular network infrastructure based on centralized Super Base Station(CSBS) is a promising solution to reduce the high construction cost and energy consumption of conventional cellular networks. With CSBS, the computing resource for communication protocol processing could be managed flexibly according the protocol load to improve the resource efficiency. Since the protocol load changes frequently and may exceed the capacity of processors, load balancing is needed. However, existing load balancing mechanisms used in data centers cannot satisfy the real-time requirement of the communication protocol processing. Therefore, a new computing resource adjustment scheme is proposed for communication protocol processing in the CSBS architecture. First of all, the main principles of protocol processing resource adjustment is concluded, followed by the analysis on the processing resource outage probability that the computing resource becomes inadequate for protocol processing as load changes. Following the adjustment principles, the proposed scheme is designed to reduce the processing resource outage probability based onthe optimized connected graph which is constructed by the approximate Kruskal algorithm. Simulation re-sults show that compared with the conventional load balancing mechanisms, the proposed scheme can reduce the occurrence number of inadequate processing resource and the additional resource consumption of adjustment greatly.展开更多
Novel centralized base station architectures integrating computation and communication functionalities have become important for the development of future mobile communication networks.Therefore,the development of dyn...Novel centralized base station architectures integrating computation and communication functionalities have become important for the development of future mobile communication networks.Therefore,the development of dynamic high-speed interconnections between baseband units(BBUs)and remote radio heads(RRHs)is vital in centralized base station design.Herein,dynamic high-speed switches(HSSs)connecting BBUs and RRHs were designed for a centralized base station architecture.We analyzed the characteristics of actual traffic and introduced a switch traffic model suitable for the super base station architecture.Then,we proposed a data-priority-aware(DPA)scheduling algorithm based on the traffic model.Lastly,we developed the dynamic HSS model based on the OPNET platform and the prototype based on FPGA.Our results show that the DPA achieves close to 100%throughput with lower latency and provides better run-time complexity than iOCF and HE-iSLIP,thereby demonstrating that the proposed switch system can be adopted in centralized base station architectures.展开更多
In centralized cellular network architecture,the concept of virtualized Base Station(VBS) becomes attracting since it enables all base stations(BSs) to share computing resources in a dynamic manner. This can significa...In centralized cellular network architecture,the concept of virtualized Base Station(VBS) becomes attracting since it enables all base stations(BSs) to share computing resources in a dynamic manner. This can significantly improve the utilization efficiency of computing resources. In this paper,we study the computing resource allocation strategy for one VBS by considering the non-negligible effect of delay introduced by switches. Specifically,we formulate the VBS's sum computing rate maximization as a set optimization problem. To address this problem,we firstly propose a computing resource schedule algorithm,namely,weight before one-step-greedy(WBOSG),which has linear computation complexity and considerable performance. Then,OSG retreat(OSG-R) algorithm is developed to further improve the system performance at the expense of computational complexity. Simulation results under practical setting are provided to validate the proposed two algorithms.展开更多
Just as Dickens wrote,it is the best of times,it is the worst of times.Ever increasing traffic demands will bring us into the era of 5G.Vast of unprecedented or even unanticipated fancy wireless applications will defi...Just as Dickens wrote,it is the best of times,it is the worst of times.Ever increasing traffic demands will bring us into the era of 5G.Vast of unprecedented or even unanticipated fancy wireless applications will definitely change our life.Regarding the beautiful visions promised by 5G,meanwhile the wireless engineers are faced with unprecedented challenges and pressures for realizing much higher spectrum efficiency and展开更多
Scleractinian corals host numerous microbial symbionts with different types of interactions. The gastric cavity of scleractinian coral, as a semiclosed subenvironment with distinct chemical characteristics(e.g., disso...Scleractinian corals host numerous microbial symbionts with different types of interactions. The gastric cavity of scleractinian coral, as a semiclosed subenvironment with distinct chemical characteristics(e.g., dissolved O2, pH, alkalinity, and nutrients), harbors a distinct microbial community and a diverse array of bacteria that can be pathogenic or beneficial. Galaxea fascicularis is one of the dominant massive scleractinian coral species on inshore fringing reefs in the northern South China Sea.Although the abundance of coral-associated bacteria has been investigated in G. fascicularis, less is known about the microorganisms in the gastric cavity. In this study, we specially isolated cultivable bacterial strains from the gastric cavity of G.fascicularis collected from Hainan Island using a noninvasive sampling approach. Among the 101 representative bacterial strains, one Vibrio coralliilyticus strain, SCSIO 43001, was found to be a temperature-dependent opportunistic pathogen of G.fascicularis. The antagonistic activity between the 100 strains and V. coralliilyticus SCSIO 43001 was tested using a modified Burkholder diffusion assay. Our results showed that V. coralliilyticus SCSIO 43001 inhibits the growth of Erythrobacter flavus and Sphingomonas yabuuchiae. Additionally, we found that three Pseudoalteromonas strains showed moderate to high antibacterial activity against V. coralliilyticus SCSIO 43001 and several other coral-associated Gram-negative bacterial strains.These results suggest that competition between the coral pathogen and other bacteria also occurs in the gastric cavity of coral, and Pseudoalteromonas strains in the gastric cavity of G. fascicularis may provide a protective role in the defense against coinhabiting coral pathogens at elevated temperature.展开更多
Nitrogen cycle is critical to maintain a healthy coral reef ecosystem.Urea can provide a source of nitrogen for coral holobiont and is important for coral calcification through degradation by urease.Despite the involv...Nitrogen cycle is critical to maintain a healthy coral reef ecosystem.Urea can provide a source of nitrogen for coral holobiont and is important for coral calcification through degradation by urease.Despite the involvement of coral-associated bacteria in nitrogen fixation,nitrification and denitrification are well recognized,to what extend urea degradation by bacteria contributing to the urea utilization by coral holobiont remains to be investigated.In this study,we demonstrate that the urea utilization is a common feature of Halomonas spp.that is a dominant genus in cultivable coral-associated bacteria.A urease operon was characterized by genome sequencing and gene knock-out technique in Halomonas meridiana SCSIO 43005,isolated from the gastric cavity of healthy scleractinian coral Galaxea fascicularis.H.meridiana showed high urease activity which was induced by urea and deletion of the urease operon reduced the capability to use urea as solo nitrogen source.Furthermore,approximately 1/3 coral-associated bacteria in the IMG/M database possess complete urease operons indicating the involvement of bacteria-derived ureases in coral holobiont.These results suggest that urease from coral-associated bacteria might be important player in the nitrogen cycling of coral reefs.展开更多
文摘Objective: To investigate the application value of midline catheters in patients with larynx cancer during the postoperative period. Methods: 150 patients with larynx cancer treated in our hospital from May 2019 to May 2022 were selected as the study objects. According to the random number method, 75 cases were divided into a control group and a study group. The study group used a midline catheter during treatment, and the control group used a Peripheral venous indwelling needle during treatment. The indwelling time, puncture times, complication rate, daily catheter maintenance cost and catheterization satisfaction rate of the two groups were compared. Result: The retention time of the study group (11.53 ± 6.91 days) was significantly higher than that of the control group (2.92 ± 1.41 days) (P . The total puncture times were significantly lower than that of the control group (P cidence of complications such as catheter blockage, catheter detachment, drug extravasation and phlebitis were lower than those of the control group. The difference was statistically significant (P < 0.05), the average daily maintenance cost of the two groups was not statistically significant (P > 0.05), and the satisfaction rate of the study group was significantly higher than that of the control group, the difference was statistically significant (P Conclusion: Compared with the Peripheral venous indwelling needle, postoperative application of a midline catheter in patients with larynx cancer can effectively reduce the number of puncture times and the incidence of catheter-related adverse reactions, and has higher economic benefits and satisfaction rate, which is worthy of clinical application.
基金This work is supported by the National Natural Science Youth Fund of China granted by No.61901452 and Innovative Project of ICT/CAS granted by No.20196110
文摘With the proliferation of the Internet of Things(IoT),various services are emerging with totally different features and requirements,which cannot be supported by the current fifth generation of mobile cellular networks(5G).The future sixth generation of mobile cellular networks(6G)is expected to have the capability to support new and unknown services with changing requirements.Hence,in addition to enhancing its capability by 10–100 times compared with 5G,6G should also be intelligent and open to adapt to the ever-changing services in the IoT,which requires a convergence of Communication,Computing and Caching(3C).Based on the analysis of the requirements of new services for 6G,this paper identifies key enabling technologies for an intelligent and open 6G network,all featured with 3C convergence.These technologies cover fundamental and emerging topics,including 3C-based spectrum management,radio channel construction,delay-aware transmission,wireless distributed computing,and network self-evolution.From the detailed analysis of these 3C-based technologies presented in this paper,we can see that although they are promising to enable an intelligent and open 6G,more efforts are needed to realize the expected 6G network.
基金supported by Beijing Natural Science Foundation under Grant number L172049the National Science and CAS Engineering Laboratory for Intelligent Agricultural Machinery Equipment GC201907-02
文摘In the 5th generation(5G)wireless communication networks,network slicing emerges where network operators(NPs)form isolated logical slices by the same cellular network infrastructure and spectrum resource.In coverage regions of access points(APs)shared by slices,device to device(D2D)communication can occur among different slices,i.e.,one device acts as D2D relay for another device serving by a different slice,which is defined as slice cooperation in this paper.Since selfish slices will not help other slices by cooperation voluntarily and unconditionally,this paper designs a novel resource allocation scheme to stimulate slice cooperation.The main idea is to encourage slice to perform cooperation for other slices by rewarding it with higher throughput.The proposed incentive scheme for slice cooperation is formulated by an optimal problem,where cooperative activities are introduced to the objective function.Since optimal solutions of the formulated problem are long term statistics,though can be obtained,a practical online slice scheduling algorithm is designed,which can obtain optimal solutions of the formulated maximal problem.Lastly,the throughput isolation indexes are defined to evaluate isolation performance of slice.According to simulation results,the proposed incentive scheme for slice cooperation can stimulate slice cooperation effectively,and the isolation of slice is also simulated and discussed.
基金supported in part by the National Science Foundationof China under Grant number 61431001the Beijing Talents Fund under Grant number 2015000021223ZK31
文摘The centralized radio access cellular network infrastructure based on centralized Super Base Station(CSBS) is a promising solution to reduce the high construction cost and energy consumption of conventional cellular networks. With CSBS, the computing resource for communication protocol processing could be managed flexibly according the protocol load to improve the resource efficiency. Since the protocol load changes frequently and may exceed the capacity of processors, load balancing is needed. However, existing load balancing mechanisms used in data centers cannot satisfy the real-time requirement of the communication protocol processing. Therefore, a new computing resource adjustment scheme is proposed for communication protocol processing in the CSBS architecture. First of all, the main principles of protocol processing resource adjustment is concluded, followed by the analysis on the processing resource outage probability that the computing resource becomes inadequate for protocol processing as load changes. Following the adjustment principles, the proposed scheme is designed to reduce the processing resource outage probability based onthe optimized connected graph which is constructed by the approximate Kruskal algorithm. Simulation re-sults show that compared with the conventional load balancing mechanisms, the proposed scheme can reduce the occurrence number of inadequate processing resource and the additional resource consumption of adjustment greatly.
基金the key project of the National Science and Technology Major Project(Grant No.2018ZX03001017)the project of the CAS engineering laboratory for intelligent agricultural machinery equipment(Grant No.GC201907-02).
文摘Novel centralized base station architectures integrating computation and communication functionalities have become important for the development of future mobile communication networks.Therefore,the development of dynamic high-speed interconnections between baseband units(BBUs)and remote radio heads(RRHs)is vital in centralized base station design.Herein,dynamic high-speed switches(HSSs)connecting BBUs and RRHs were designed for a centralized base station architecture.We analyzed the characteristics of actual traffic and introduced a switch traffic model suitable for the super base station architecture.Then,we proposed a data-priority-aware(DPA)scheduling algorithm based on the traffic model.Lastly,we developed the dynamic HSS model based on the OPNET platform and the prototype based on FPGA.Our results show that the DPA achieves close to 100%throughput with lower latency and provides better run-time complexity than iOCF and HE-iSLIP,thereby demonstrating that the proposed switch system can be adopted in centralized base station architectures.
基金funded by the key project of the National Natural Science Foundation of China (No.61431001)the National High-Tech R&D Program (863 Program 2015AA01A705)New Technology Star Plan of Beijing (No.xx2013052)
文摘In centralized cellular network architecture,the concept of virtualized Base Station(VBS) becomes attracting since it enables all base stations(BSs) to share computing resources in a dynamic manner. This can significantly improve the utilization efficiency of computing resources. In this paper,we study the computing resource allocation strategy for one VBS by considering the non-negligible effect of delay introduced by switches. Specifically,we formulate the VBS's sum computing rate maximization as a set optimization problem. To address this problem,we firstly propose a computing resource schedule algorithm,namely,weight before one-step-greedy(WBOSG),which has linear computation complexity and considerable performance. Then,OSG retreat(OSG-R) algorithm is developed to further improve the system performance at the expense of computational complexity. Simulation results under practical setting are provided to validate the proposed two algorithms.
文摘Just as Dickens wrote,it is the best of times,it is the worst of times.Ever increasing traffic demands will bring us into the era of 5G.Vast of unprecedented or even unanticipated fancy wireless applications will definitely change our life.Regarding the beautiful visions promised by 5G,meanwhile the wireless engineers are faced with unprecedented challenges and pressures for realizing much higher spectrum efficiency and
基金supported by the National Key R & D Program of China (Grant Nos. 2018YFC1406500 & 2017YFC0506303)the National Natural Science Foundation of China (Grant Nos. 41706172, 31625001 & 41376174)the Hainan Provincial Key R & D (Grant No. ZDYF2018108)
文摘Scleractinian corals host numerous microbial symbionts with different types of interactions. The gastric cavity of scleractinian coral, as a semiclosed subenvironment with distinct chemical characteristics(e.g., dissolved O2, pH, alkalinity, and nutrients), harbors a distinct microbial community and a diverse array of bacteria that can be pathogenic or beneficial. Galaxea fascicularis is one of the dominant massive scleractinian coral species on inshore fringing reefs in the northern South China Sea.Although the abundance of coral-associated bacteria has been investigated in G. fascicularis, less is known about the microorganisms in the gastric cavity. In this study, we specially isolated cultivable bacterial strains from the gastric cavity of G.fascicularis collected from Hainan Island using a noninvasive sampling approach. Among the 101 representative bacterial strains, one Vibrio coralliilyticus strain, SCSIO 43001, was found to be a temperature-dependent opportunistic pathogen of G.fascicularis. The antagonistic activity between the 100 strains and V. coralliilyticus SCSIO 43001 was tested using a modified Burkholder diffusion assay. Our results showed that V. coralliilyticus SCSIO 43001 inhibits the growth of Erythrobacter flavus and Sphingomonas yabuuchiae. Additionally, we found that three Pseudoalteromonas strains showed moderate to high antibacterial activity against V. coralliilyticus SCSIO 43001 and several other coral-associated Gram-negative bacterial strains.These results suggest that competition between the coral pathogen and other bacteria also occurs in the gastric cavity of coral, and Pseudoalteromonas strains in the gastric cavity of G. fascicularis may provide a protective role in the defense against coinhabiting coral pathogens at elevated temperature.
基金supported by the National Key R&D Program of China(Grant Nos.2017YFC0506303&2018YFC1406500)the National Natural Science Foundation of China(Grant Nos.91951203,41706172,31625001&41376174)+2 种基金the Hainan Provincial Key R&D Program(Grant No.ZDYF2018108)supported by the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(Grant No.GML2019ZD0407)the Guangdong Local Innovation Team Program(Grant No.2019BT02Y262)。
文摘Nitrogen cycle is critical to maintain a healthy coral reef ecosystem.Urea can provide a source of nitrogen for coral holobiont and is important for coral calcification through degradation by urease.Despite the involvement of coral-associated bacteria in nitrogen fixation,nitrification and denitrification are well recognized,to what extend urea degradation by bacteria contributing to the urea utilization by coral holobiont remains to be investigated.In this study,we demonstrate that the urea utilization is a common feature of Halomonas spp.that is a dominant genus in cultivable coral-associated bacteria.A urease operon was characterized by genome sequencing and gene knock-out technique in Halomonas meridiana SCSIO 43005,isolated from the gastric cavity of healthy scleractinian coral Galaxea fascicularis.H.meridiana showed high urease activity which was induced by urea and deletion of the urease operon reduced the capability to use urea as solo nitrogen source.Furthermore,approximately 1/3 coral-associated bacteria in the IMG/M database possess complete urease operons indicating the involvement of bacteria-derived ureases in coral holobiont.These results suggest that urease from coral-associated bacteria might be important player in the nitrogen cycling of coral reefs.