Dear Editor, Streptococcus suis （S. suis） is a Gram-positive, facultative anaerobic coccus and an important emerging pathogen. It is associated with bacterial meningitis in adults, especially in southeastern Asia （...Dear Editor, Streptococcus suis （S. suis） is a Gram-positive, facultative anaerobic coccus and an important emerging pathogen. It is associated with bacterial meningitis in adults, especially in southeastern Asia （Wertheim et al., 2009）. A striking feature of S. suis infection is the resulting complications, which may include deafness and vestibular dysfunction. Complications of some kind affect 50% of S. suis patients in Europe and 73% of those in Asia （Gottschalk et al., 2010）. Some S. suis surface-associated factors, such as the capsule and Fhb, may affect the pathogenesis of meningitis. Of these secreted factors, suilysin was found to be the most important. It has been found to be toxic to various types of cells （Lalonde et al., 2000）. It is also involved in modulation of the inter- actions of S. suis with different host cells （Charland et al.,展开更多
文摘Dear Editor, Streptococcus suis （S. suis） is a Gram-positive, facultative anaerobic coccus and an important emerging pathogen. It is associated with bacterial meningitis in adults, especially in southeastern Asia （Wertheim et al., 2009）. A striking feature of S. suis infection is the resulting complications, which may include deafness and vestibular dysfunction. Complications of some kind affect 50% of S. suis patients in Europe and 73% of those in Asia （Gottschalk et al., 2010）. Some S. suis surface-associated factors, such as the capsule and Fhb, may affect the pathogenesis of meningitis. Of these secreted factors, suilysin was found to be the most important. It has been found to be toxic to various types of cells （Lalonde et al., 2000）. It is also involved in modulation of the inter- actions of S. suis with different host cells （Charland et al.,
