THE DETECTION OF CD56 AND EPSTEIN-BARR VIRUS IN T-CELL LYMPHOMAS

Objective: To study the relationship between EBV infection and the expression of CD56 in T cell lymphomas (TCLs). Methods: 46 cases of TCLs and 15 cases of reactive hyperplasia of lymphonodes (RHs) were detected CD56 by immunohistochemistry and EBERs by in situ hybridization. Results: 8 cases of 46 TCLs (17.4%) showed CD56 positive. On sites, CD56 positive rate of nasopharyngeal TCLs was highest (5/17, 29.4%), and on subtypes, that of DLs was highest (6/16, 37.5%). Additionally, 4 RHs were also CD56 positive. Of 46 TCLs, 24 showed expression of EBERs. There were only 4 TCLs expressing both CD56 and EBERs. Conclusion: The expression of CD56 was not especially for TCLs that EBV infected. EBV infection was not related with CD56 positive TCLs. The findings also suggested the expression of CD56 in TCLs be possibly related to original sites and subtypes of TCLs.

205例新型冠状病毒肺炎病例临床分析

目的了解新型冠状病毒肺炎的基本疫情特征,为防范新冠肺炎提供科学的依据和制定合理的防治措施。方法收集2020年1月至3月宜昌市第三人民医院收治并确诊病例其中的205例新型冠状病毒肺炎病人的流行病学史、临床特征、实验室检查结果、影像学结果等资料,建立数据库,进行回顾性分析。结果 205例确诊病例中平均发病年龄为(56.0±16.2)岁,前期以有武汉疫区接触史确诊病例为主,后以本地不明接触史确诊病例为主;大部分表现为普通型和轻症。通过统计学分析,年龄、性别、职业、接触史、与病情严重程度均无统计学意义(P>0.05)。有无基础疾病与病情严重程度具有统计学意义(χ~2=31,P<0.05)。结论临床症状以发热咳嗽为主,重症病人与有基础疾病相关。降钙素原对病毒感染无参考意义,本次病毒致肺部炎症及胸膜肥厚粘连,乳酸增高是其特点,迄今为止,宜昌市疫情已得到控制,但日后的防控依然要有足够的重视。