目的:系统评价夜间低血压与正常眼压性青光眼(Normal-Tension Glaucoma,NTG)发生、发展的相关性,为NTG的临床诊断、预防和治疗提供理论指导。方法:搜索在PubMed、Embase、中国生物医学文献数据库(China Biology Medicine disc,CBMdisc)...目的:系统评价夜间低血压与正常眼压性青光眼(Normal-Tension Glaucoma,NTG)发生、发展的相关性,为NTG的临床诊断、预防和治疗提供理论指导。方法:搜索在PubMed、Embase、中国生物医学文献数据库(China Biology Medicine disc,CBMdisc)、中国知网数据库(China National Knowledge Infrastructure,CNKI)、万方数据库等数据库公开发表的,并且符合标准的关于比较NTG与正常人群夜间血压的前瞻性研究和横断面研究。研究文献的筛选是基于文献的研究类型、纳入标准和排除标准,而文献质量评估则采用美国医疗保健研究与质量局(The Agency for Healthcare Research and Quality,AHRQ)公布的11项评估表。研究的合并效应值加权均数差(Weighted Mean Difference,WMD)则是使用Review Manager 5.2软件来计算。结果:最终纳入3项前瞻性研究和1项横断面研究,共计247例参与者。使用随机效应模型下的NTG患者与正常对照组相比夜间收缩压(Systolic Blood Pressure,SBP)在统计学上显著降低(P=0.04),异质性检验(χ^2=7.43,P=0.06,I 2=60%)。使用固定效应模型下的NTG患者与正常对照组相比夜间舒张压(Diastolic Blood Pressure,DBP)在统计学上显著降低(P=0.0002),异质性检验(χ^2=3.28,P=0.35,I 2=9%)。结论:Meta分析表明,与正常对照组相比,NTG患者夜间血压(包括收缩压和舒张压)均发生明显降低,提示夜间低血压有可能是NTG发病的一项重要的危险因素,这无疑为NTG的临床诊断、预防和治疗提供了一种非常有价值的思路和方法。展开更多
Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sut...Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sutures. Methods: A retrospective evaluation of 74 eyes with glaucoma (COAG, CNAG, PXFG) of 74 patients who underwent filtration surgery in our department during 1999. All the patients included in the study had 6-12展开更多
文摘目的:系统评价夜间低血压与正常眼压性青光眼(Normal-Tension Glaucoma,NTG)发生、发展的相关性,为NTG的临床诊断、预防和治疗提供理论指导。方法:搜索在PubMed、Embase、中国生物医学文献数据库(China Biology Medicine disc,CBMdisc)、中国知网数据库(China National Knowledge Infrastructure,CNKI)、万方数据库等数据库公开发表的,并且符合标准的关于比较NTG与正常人群夜间血压的前瞻性研究和横断面研究。研究文献的筛选是基于文献的研究类型、纳入标准和排除标准,而文献质量评估则采用美国医疗保健研究与质量局(The Agency for Healthcare Research and Quality,AHRQ)公布的11项评估表。研究的合并效应值加权均数差(Weighted Mean Difference,WMD)则是使用Review Manager 5.2软件来计算。结果:最终纳入3项前瞻性研究和1项横断面研究,共计247例参与者。使用随机效应模型下的NTG患者与正常对照组相比夜间收缩压(Systolic Blood Pressure,SBP)在统计学上显著降低(P=0.04),异质性检验(χ^2=7.43,P=0.06,I 2=60%)。使用固定效应模型下的NTG患者与正常对照组相比夜间舒张压(Diastolic Blood Pressure,DBP)在统计学上显著降低(P=0.0002),异质性检验(χ^2=3.28,P=0.35,I 2=9%)。结论:Meta分析表明,与正常对照组相比,NTG患者夜间血压(包括收缩压和舒张压)均发生明显降低,提示夜间低血压有可能是NTG发病的一项重要的危险因素,这无疑为NTG的临床诊断、预防和治疗提供了一种非常有价值的思路和方法。
文摘Purpose: To evaluate the use of releasable sutures in filtration surgery by comparing the results and the rate of post-operative complications in eyes which underwent filtration surgery with and without releasable sutures. Methods: A retrospective evaluation of 74 eyes with glaucoma (COAG, CNAG, PXFG) of 74 patients who underwent filtration surgery in our department during 1999. All the patients included in the study had 6-12
