AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Obser...AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Observational,cross-sectional,analytic study,in which 104 Egyptian volunteers were included.Both upper lids were examined,using“Sirius CSO”machine.Each eyelid was given a degree of meibomian gland loss(MGL),which was calculated by the software of the machine.RESULTS:Mean percentage MGL in right upper lid was of 30.9%±12.6%,and that of left upper lid was 32.6%±11.8%.Thirty-four volunteers(32.7%)had first-degree MGL in their right upper lid,and 67.3%had second-degree loss.One volunteer(1%)had zero-degree MGL in left upper lid,28(26.9%)had first-degree loss,and 75(72.1%)had second-degree loss.Degree of MGL in right upper eyelid was not related to age,but degree of MGL in left upper eyelid increased with age.There was statistically significant difference between both genders for degree of MGL in right eye(P=0.036)and in left eye(P=0.027).CONCLUSION:Noncontact meibography is a useful non-invasive tool for diagnosing MGL.MGL is diagnosed in 100%of apparently normal individuals;26.9%-32.7%of which have first-degree MGL,and 67.3%-72.1%have second-degree MGL.展开更多
AIM:To study retinal microvascular and microstructural alterations in meibomian gland dysfunction(MGD)in severely obese population using optical coherence tomography angiography(OCTA).METHODS:Twelve MGD patients with ...AIM:To study retinal microvascular and microstructural alterations in meibomian gland dysfunction(MGD)in severely obese population using optical coherence tomography angiography(OCTA).METHODS:Twelve MGD patients with severely obese population(PAT group;24 eyes)and 12 healthy controls(HC group;24 eyes)were recruited.OCTA images were segmented into five[superior(S),nasal(N),inferior(I),temporal(T),and central foveal(C)]or nine[inner superior(IS),outer superior(OS),inner nasal(IN),outer nasal(ON),inner inferior(II),outer inferior(OI),inner temporal(IT),outer temporal(OT),and C]subregions.The superficial vessel density(SVD),retinal thickness(RT),foveal avascular zone(FAZ)parameters,and retinal volume were measured.RESULTS:Visual acuity was significantly different between two groups(0.8±0.17 in PAT group vs 0.2±0.06 in HC group).SVD was significantly lower in PATs in N,T,OS,IN,OT,and ON.The area under the receiver operating characteristic curve(AUC)for T was 0.961[95% confidence interval(CI):0.908 to 1.000],for OS was 0.962(95%CI:0.915 to 1.000).RT was significantly lower in PATs in IS,OS,OI,OT,ON,IT,IN,and II.AUC for OT was 0.935(95%CI:0.870 to 0.999),for IS was 0.915(95%CI:0.838 to 0.992).Angiography results showed significantly lower area and perimeter of FAZ,SVD of the inner retina and both retinal volume and the average volume thickness in the PAT group.CONCLUSION:Vision may be affected in patients with MGD due to changes in retinal microvessels and microstructures.These changes detected by OCTA may be a potential marker for diagnosing MGD in severe obesity.展开更多
AIM:To investigate the prevalence of color vision deficiency(CVD)among college students and their quality of life(QoL)in a Chinese college.METHODS:This cross-sectional study was performed in Sichuan University in Chen...AIM:To investigate the prevalence of color vision deficiency(CVD)among college students and their quality of life(QoL)in a Chinese college.METHODS:This cross-sectional study was performed in Sichuan University in Chengdu,China.The questionnaire containing participants’demographic data,as well as CVD related QoL was distributed to students who were screened as CVD[by Color Vision Examination Plates(Version 6)]in 2022 freshman entrance examination.Color blindness QoL(CBQoL)and utility analysis were used to evaluate the QoL of CVD students.RESULTS:There were 381 of 17303(2.20%)students screened as CVD,including 368(4.11%)males and 13(0.16%)females.A total of 317 students completed the questionnaire,the response rate was 83.20%.Only 166 participants(52.3%)knew they have CVD before the physical examination for college entrance examination,while a total of 145 participants(45.74%)hoped to be diagnosed earlier.The medians of CBQoL score and utility were 5.85(range 2.2-6)and 1(range 0-1),respectively.The proportions of students whose QoL is affected by CVD were 67.63%(211/312)and 42.27%(134/317)measured by CBQoL and utility analysis respectively.CONCLUSION:The prevalence of CVD in males is much higher than that in females.The time when CVD students first became aware of their CVD is relatively late.The QoL of the study population is quite high,while a large proportion of students’QoL are affected by CVD.It is suggested that as a congenital defect,CVD screening in China should be earlier,and appropriate guidance and support are needed for CVD patients to help them better adapt to life,study,and work.展开更多
文摘AIM:To develop normative data for meibomian gland dysfunction(MGD)parameters,using non-contact meibography technique of Sirius Costruzione Strumenti Oftalmici(CSO)machine,in an Egyptian population sample.METHODS:Observational,cross-sectional,analytic study,in which 104 Egyptian volunteers were included.Both upper lids were examined,using“Sirius CSO”machine.Each eyelid was given a degree of meibomian gland loss(MGL),which was calculated by the software of the machine.RESULTS:Mean percentage MGL in right upper lid was of 30.9%±12.6%,and that of left upper lid was 32.6%±11.8%.Thirty-four volunteers(32.7%)had first-degree MGL in their right upper lid,and 67.3%had second-degree loss.One volunteer(1%)had zero-degree MGL in left upper lid,28(26.9%)had first-degree loss,and 75(72.1%)had second-degree loss.Degree of MGL in right upper eyelid was not related to age,but degree of MGL in left upper eyelid increased with age.There was statistically significant difference between both genders for degree of MGL in right eye(P=0.036)and in left eye(P=0.027).CONCLUSION:Noncontact meibography is a useful non-invasive tool for diagnosing MGL.MGL is diagnosed in 100%of apparently normal individuals;26.9%-32.7%of which have first-degree MGL,and 67.3%-72.1%have second-degree MGL.
基金Supported by National Natural Science Foundation of China(No.82160195)Science and Technology Project of Jiangxi Provincial Department of Education(No.GJJ200169)+1 种基金Science and Technology Project of Jiangxi Province Health Commission of Traditional Chinese Medicine(No.2020A0087)Science and Technology Project of Jiangxi Health Commission(No.202130210).
文摘AIM:To study retinal microvascular and microstructural alterations in meibomian gland dysfunction(MGD)in severely obese population using optical coherence tomography angiography(OCTA).METHODS:Twelve MGD patients with severely obese population(PAT group;24 eyes)and 12 healthy controls(HC group;24 eyes)were recruited.OCTA images were segmented into five[superior(S),nasal(N),inferior(I),temporal(T),and central foveal(C)]or nine[inner superior(IS),outer superior(OS),inner nasal(IN),outer nasal(ON),inner inferior(II),outer inferior(OI),inner temporal(IT),outer temporal(OT),and C]subregions.The superficial vessel density(SVD),retinal thickness(RT),foveal avascular zone(FAZ)parameters,and retinal volume were measured.RESULTS:Visual acuity was significantly different between two groups(0.8±0.17 in PAT group vs 0.2±0.06 in HC group).SVD was significantly lower in PATs in N,T,OS,IN,OT,and ON.The area under the receiver operating characteristic curve(AUC)for T was 0.961[95% confidence interval(CI):0.908 to 1.000],for OS was 0.962(95%CI:0.915 to 1.000).RT was significantly lower in PATs in IS,OS,OI,OT,ON,IT,IN,and II.AUC for OT was 0.935(95%CI:0.870 to 0.999),for IS was 0.915(95%CI:0.838 to 0.992).Angiography results showed significantly lower area and perimeter of FAZ,SVD of the inner retina and both retinal volume and the average volume thickness in the PAT group.CONCLUSION:Vision may be affected in patients with MGD due to changes in retinal microvessels and microstructures.These changes detected by OCTA may be a potential marker for diagnosing MGD in severe obesity.
文摘AIM:To investigate the prevalence of color vision deficiency(CVD)among college students and their quality of life(QoL)in a Chinese college.METHODS:This cross-sectional study was performed in Sichuan University in Chengdu,China.The questionnaire containing participants’demographic data,as well as CVD related QoL was distributed to students who were screened as CVD[by Color Vision Examination Plates(Version 6)]in 2022 freshman entrance examination.Color blindness QoL(CBQoL)and utility analysis were used to evaluate the QoL of CVD students.RESULTS:There were 381 of 17303(2.20%)students screened as CVD,including 368(4.11%)males and 13(0.16%)females.A total of 317 students completed the questionnaire,the response rate was 83.20%.Only 166 participants(52.3%)knew they have CVD before the physical examination for college entrance examination,while a total of 145 participants(45.74%)hoped to be diagnosed earlier.The medians of CBQoL score and utility were 5.85(range 2.2-6)and 1(range 0-1),respectively.The proportions of students whose QoL is affected by CVD were 67.63%(211/312)and 42.27%(134/317)measured by CBQoL and utility analysis respectively.CONCLUSION:The prevalence of CVD in males is much higher than that in females.The time when CVD students first became aware of their CVD is relatively late.The QoL of the study population is quite high,while a large proportion of students’QoL are affected by CVD.It is suggested that as a congenital defect,CVD screening in China should be earlier,and appropriate guidance and support are needed for CVD patients to help them better adapt to life,study,and work.
