一种中药复方提取液空气气溶胶消毒剂的消毒效果

目的:观察中药复方提取液空气气溶胶消毒剂的消毒效果。方法:借助气溶胶喷雾机将中药复方提取液呈气溶胶状喷洒于室内空气中,同时同普通喷雾器喷撒、中药熏蒸作对照,以通风法为空白对照、紫外线照射、氯剂消毒为阳性对照组对照,分别于消毒前、消毒后30 min、1 h、2 h、4 h各时间段采用平板空气暴露法取样,进行细菌培养,观察各种消毒方法对室内空气消毒的效果及维持时间。结果:各组消毒后30 min、1 h、2 h、4 h空气菌落数均有明显下降,同对照组比较有明显差异(P Objective: Observe the disinfection effect of air aerosol disinfectant extracted from traditional Chinese medicine compound. Methods: With the help of aerosol spray machine, the extract of traditional Chinese medicine compound was sprayed into the indoor air in the form of aerosol gel. At the same time, it was compared with ordinary spray spraying and traditional Chinese medicine fumigation. With ventilation method as the blank control, ultraviolet radiation, and chlorine disinfection as the positive control group, the plate air exposure method was used to sample before disinfection, 30 min, 1 h, 2 h, and 4 h after disinfection, respectively, for bacterial culture, Observe the effectiveness and maintenance time of various disinfection methods for indoor air disinfection. Result: The results showed that the air bacterial count in each group decreased significantly at 30 minutes, 1 hour, 2 hours, and 4 hours after disinfection, and there was a significant difference compared to the control group (P < 0.05). The disinfection effect of aerosol spray group 30 minutes after disinfection was similar to that of ultraviolet control group, but there was significant difference compared with other groups (P < 0.05);One hour after disinfection, the colony of ultraviolet control group was lower than that of aerosol spray group, and the effect was better than that of aerosol spray group;However, with the continuous extension of the end time of disinfection, the number of air colonies in each group continued to increase, but at the same time point, the number of air colonies in the aerosol spray group was significantly lower than that in the control groups at 2 h and 4 h after disinfection, with a statistically significant difference (P < 0.05). Conclusion: The compound extract aerosol disinfectant has the same disinfection effect as ultraviolet disinfection. Both groups have good disinfection effect, which can effectively prevent bacterial pollution in indoor air, but it is better than ordinary spray spraying, traditional Chinese medicine fumigation, and chlorine disinfection. Aerosol disinfectant is more durable in maintaining disinfection time.

帕金森病患者吞咽困难的个体化康复治疗

帕金森病(Parkinson’s disease)是严重影响老年人健康的神经系统变性疾病。吞咽障碍是PD常见的非运动障碍,在临床上具有隐蔽性、进行性发展等特点,是吸入性肺炎致死的重要原因。PD吞咽功能障碍可以通过相关量表、纤维内窥镜吞咽检查(FEES)和电视透视吞咽检查(VFSS)等进行评估。目前尚无证据证实药物治疗能够完全改善患者的吞咽功能。近年来,康复治疗作为针对PD患者吞咽障碍的治疗手段备受关注。故本文围绕PD患者吞咽困难的评估及康复治疗进展予以综述。Parkinson’s disease (PD) is a neurodegenerative disease that seriously affects the health of the elderly. Dysphagia is a common non-motor disorder in PD. It has the characteristics of concealment and progressive development in clinical practice, and is an important cause of death in aspiration pneumonia PD swallowing dysfunction can be related to scale, fiber endoscope (feeds) and TV fluoroscopy swallow check (VFSS) and so on. At present, there is no evidence that drug treatment can completely improve the swallowing function of patients. In recent years, rehabilitation therapy as a treatment for PD patients with swallowing difficulties. Therefore, this article around the assessment of the PD patients with dysphagia and rehabilitation progress were reviewed.

基于气机升降理论浅述谢晶日教授治疗胃食管反流病经验

谢晶日教授治疗胃食管反流病经验丰富,认为胃食管反流病是由于情志不遂,饮食不节,平素脾胃虚弱等各种因素导致脾气当升不升,胃气当降不降,肝不随脾升,胆不随胃降,以致胃气上逆,上犯食管而形成本病。临证时,谢晶日教授强调从气机升降理论治疗胃食管反流病的重要性,强调调畅气机,重视情志因素在治疗胃食管反流病的作用,临床多获良效。Professor Xie Jingri has rich experience in treating gastroesophageal reflux disease. He believes that the disease is caused by various factors such as emotional imbalance, improper diet, and underlying weakness of the spleen and stomach, leading to the failure of spleen Qi to rise and stomach Qi to descend. In his view, when the liver fails to ascend with the spleen and the gallbladder fails to descend with the stomach, gastric Qi reverses and rises, affecting the esophagus and causing the disease. In clinical practice, Professor Xie Jingri emphasizes the importance of the theory of pneumatosis elevation and reduction in treating gastroesophageal reflux disease, highlighting the importance of regulating pneumatosis and considering the role of emotional factors in the treatment of the disease, which has resulted in positive clinical outcomes.

Teachback结合思维导图在腰椎间盘突出症患者健康教育中的应用

腰椎间盘突出症是一种常见的脊柱疾病,教育患者对疾病和康复的理解至关重要。本综述探讨了不同健康教育模型在腰椎间盘突出症患者教育中的应用。Teachback法和思维导图等交互式教育模式能提高患者对康复信息的理解和记忆,增强自我管理能力。然而,应用这些方法在实际临床中面临着一些挑战和限制,包括培训医务人员需具备高技能水平、需要更多资源和时间,以及个体差异可能影响教育效果。未来研究需关注长期效果和实际应用的可行性,以优化腰椎间盘突出症患者的健康教育策略。选择适当的健康教育模型应考虑患者的需求,以提升康复效果和患者满意度。Lumbar disc herniation is a common spinal disorder, and educating patients about the disease and rehabilitation is crucial. This review examines the application of different health education models in the education of patients with lumbar disc herniation. Interactive education models such as the Teachback method and mind mapping can improve patients’ understanding and retention of rehabilitation information and enhance self-management skills. However, the application of these methods faces some challenges and limitations in actual clinical practice, including the need for a high skill level to train medical staff, the need for more resources and time, and the possibility that individual differences may affect educational outcomes. Future studies need to focus on the long-term effects and feasibility of practical application to optimize health education strategies for patients with lumbar disc herniation. Selection of appropriate health education models should take into account the needs of patients to enhance rehabilitation outcomes and patient satisfaction.

慢性乙肝患者病耻感现状及影响因素分析

目的:探讨慢性乙型肝炎(CHB)患者的病耻感状况及其影响因素。方法:2023年7月至2024年6月我院就诊的慢性乙肝患者120例,收集所有患者基本信息。采用SS患者病耻感水平,总结慢性乙肝患者病耻感现况;应用Logistic回归模型,分析慢性乙肝患者病耻感水平的影响因素。结果:此项研究收回有效问卷120份,他们在疾病羞耻度评分量表上的成绩跨度介于26至106分之间,平均得分71.16 ± 14.82分。经过对单一变量的研究发现,乙型肝炎患者的羞愧心理与其性别、年纪、教育水平、工作类型、婚姻状态、患病时间以及对疾病的处理方法存在显著性关联(P值小于0.05)。经由多变量线性回归考察得出,影响慢性乙型肝炎患者羞愧感受的关键变量包括年纪、教育水平、婚配情形及其应对策略,且统计学意义显著(P值小于0.05)。结论:乙型肝炎携带者普遍存在较强的疾病羞愧心理,此情绪状态与患者的年纪、教育水平、婚姻状况、得到的社交援助及应对策略紧密相关,针对此类情况,应实施有效的心理干预措施,降低乙型肝炎患者的羞病感,帮助其更顺利地融入社会。Objective: To explore the stigma of patients with chronic hepatitis B (CHB) and its influencing factors. Methods: There were 120 cases of chronic hepatitis B patients attending our hospital from July 2023 to June 2024, and the basic information of all patients was collected. SS patients’ level of stigma was used to summarize the current status of chronic hepatitis B patients’ stigma;Logistic regression model was applied to analyze the influencing factors of chronic hepatitis B patients’ level of stigma. Results: In this study, 120 valid questionnaires were returned and their scores on the Disease Shame Rating Scale spanned between 26 and 106 with a mean score of 71.16 ± 14.82. Upon examination of the single variables, it was found that there was a significant association (p-value less than 0.05) between the shame of patients with Hepatitis B and their gender, age, level of education, type of work, marital status, duration of illness, and their approach to the disease. A multivariate linear regression examination revealed that the key variables affecting the feelings of shame among chronic hepatitis B patients included age, level of education, marital status, and their coping strategies, and were statistically significant (p < 0.05). Conclusions: Hepatitis B carriers generally have strong disease shame, and this emotional state is closely related to the patient’s age, education level, marital status, social assistance received, and coping strategies. Effective psychological interventions should be implemented to address this situation, to reduce the disease shame of patients with hepatitis B, and to help them integrate into the community more smoothly.

肝癌伴微血管侵犯的相关因素研究

肝癌是严重危害人类健康的重大疾病,到2025年,肝癌患者新增将突破100万。肝细胞癌(hepatocellular carcinoma, HCC)是肝癌中最常见的一种,约占85%。我国人口基数较大,是肝癌发病重灾区,发病率在恶性肿瘤中处于第四位,2022年新增肝癌患者为39.9万例,每年因为肝癌而导致的死亡人数约是全世界的一半,在我国的恶性肿瘤致死率排名中,位居第二位。目前最好的根治方法仍然是手术切除,但是肝细胞癌的预后还是不佳。肿瘤的分化程度、数目、大小、有无转移等都会影响到肝癌的预后。在临床上,越来越多的研究表明,手术后经病理确认伴有微血管侵犯(Microvascular invasion, MVI)的患者,其复发率明显升高,生存率明显下降。因此,肝癌的恶性程度及预后,除了与肿瘤大小、数量、远处转移等因素有关外,还与肝癌是否伴有MVI密切相关。因此,判断肝细胞癌是否发生MVI并及时采取适当的干预措施是提高肝细胞癌患者生存率的关键。

复合骨修复支架材料的研究现状

骨组织工程是一个结合了支架材料、种子细胞和生长因子的复杂系统。在组织工程的研究中,支架材料扮演着重要角色,它们为细胞提供必要的结构支持,成为引导组织生长和构建的基础模板。本文将深入探讨各类支架材料的当前研究进展。

常染色体显性遗传性多囊肾患者妊娠后影响及治疗研究进展

常染色体显性遗传性多囊肾(ADPKD)是一种常见的肾脏遗传病,为单基因遗传,以双侧肾囊肿为特征,导致肾功能进行性下降。近年来基因检测技术和一些新药物的使用,使得ADPKD的管理取得了长足进步。但作为最常见的单基因遗传性肾病ADPKD患者的发病年龄与育龄期妇女高度重合,母亲和婴儿的妊娠结局与普通人群不同,妊娠并发症的长期后果在ADPKD中也很常见。本文将对ADPKD患者妊娠后的影响、妊娠期间的多方面治疗与管理进行综述。Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a prevalent genetic kidney disorder inherited through a single gene, characterized by bilateral renal cysts that lead to a progressive decline in renal function. Recent advancements in genetic testing technology and the introduction of novel medications have significantly improved the management of ADPKD. However, as the most prevalent monogenic inherited kidney disease, ADPKD patients often experience onset during childbearing age, leading to distinctive pregnancy outcomes for both mothers and infants compared to the general population. Additionally, long-term consequences of pregnancy complications are common in ADPKD. This review aims to outline the impact of pregnancy on ADPKD patients and explore multiple treatment and management strategies during pregnancy.

心力衰竭患者入院时血清钠水平对1年内再入院预测价值研究

背景:心力衰竭(心衰)是常见的一种慢性疾病,随着社会的进步与发展,影响心衰的因素也研究了很多,但对于心衰患者入院时血清钠的水平对1年内再入院的预测价值尚有争议。目的:分析心衰患者血清钠的水平与1年内再入院的关系。方法:这项研究是一项回顾性队列研究。所有心衰住院患者的数据均来自PhysioNet数据库。该数据库整合了中国四川省自贡市第四人民医院2016年12月至2019年6月期间收治的2008名诊断为心衰患者的咨询记录和随访数据。我们分析了因心衰入院治疗的876例心衰患者的临床资料,同时根据入院的血清钠水平分为三组:低血清钠组(107.5~136.8 mmol/L, n = 292)、中血清钠组(136.9~140 mmol/L, n = 285)和高血清钠组(140.1~154 mmol/L, n = 299)。采用Cox回归、分层分析和阈值效应分析、KM曲线,探究血清钠与心衰患者1年内再入院之间的关联性。结果:在阈值分析中,血清钠每增加1mmol/L,心衰患者1年内再入院的风险显著降低3%,风险比(HR)及其95% CI为0.97 (0.94~0.99)。使用三个模型分析不同血钠水平的患者,校正后,高钠组相对于低钠组和中钠组风险较低,结果事件存在显著差异,HR及其95% CI分别为0.69 (0.58~0.81, P < 0.001)、0.70 (0.59~0.83, P < 0.001)和0.72 (0.57~0.92, P = 0.007)。亚组分析显示,血清钠水平对结果事件有稳定的影响,不受协变量(性别、年龄、身体质量指数(BMI)、糖尿病、慢性肾脏病(CKD)、心肌梗死、慢性阻塞性肺疾病(COPD)、利尿剂、肌酐、尿酸、钾、氯、N末端B型利钠肽原)的影响。结论:血清钠与心衰患者1年内再入院的结局事件呈负相关。较高的血清钠会使心衰患者1年内再入院的风险降低。因此,首次住院时血清钠的水平可能是一个心衰患者再入院有价值的预测因素。

单通道内镜与单侧双通道内镜(UBE)减压治疗腰椎管狭窄症临床疗效的Meta分析

目的:通过Meta分析对比单通道内镜及单侧双通道内镜(UBE)在治疗腰椎管狭窄症的临床疗效。方法:检索PubMed、Cochrane Library、Embase和Web of Science等数据库(从建库到2023年10月)对单通道内镜和单侧双通道内镜治疗腰椎管狭窄症疗效的临床研究进行检索。提取纳入研究的结局指标,包括:腰部和腿部疼痛的VAS评分、术后ODI评分、手术时间、住院天数、并发症发生率、手术优良率。使用Revman 5.3软件对数据进行统计学分析,单个率采用优势比(odds ratios, OR),连续性变量采用加权平均差异(weighted mean difference, WMD),并给出可信区间(confidence interval, CI)为95%。结果:总共有6项研究,515名患者被纳入该Meta分析。UBE手术相对于单通道内镜有着更短的手术时间(WMD −12.37, 95%CI −22.15~−2.6, P = 0.01)。两组患者在腰痛VAS评分[术后第一天(WMD 0.27, 95%CI −0.29~0.82, P = 0.35)、末次随访(WMD −0.02, 95%CI −0.1~0.06, P = 0.63)]、腿痛VAS评分[术后第一天(WMD −0.17, 95%CI −0.43~0.09, P = 0.20)、末次随访(WMD 0.03, 95%CI −0.15~0.15, P = 0.51)、ODI评分(WMD −0.1, 95%CI −0.67~0.47, P = 0.73)、并发症(OR 0.72, 95%CI 0.37~1.41, P = 0.34)、住院天数(WMD −0.06, 95%CI −0.27~0.15, P = 0.56)、手术优良率(OR 1.32, 95%CI 0.69~2.53, P = 0.56)等方面均无明显差异。结论:UBE和单通道内镜治疗腰椎管狭窄症的临床疗效和并发症发生率无明显差异。而UBE与单通道内镜组相比有着更短的手术时间。Objective: To compare the clinical efficacy of uniportal endoscoppic and biportal endoscopic (UBE) decompression for the treatment of lumbar spinal stenosis through meta-analysis. Methods: PubMed, Cochrane Library, Embase and Web of Science databases were searched (from the establishment of the database to October 2023) to compare the clinical studies on the clinical efficacy of uniportal and biportal endoscopy in the treatment of lumbar spinal stenosis. The outcome indicators included in the study were extracted, including VAS score of lumbar and leg pain, postoperative ODI score, operation time, length of hospital stay, complication rate, and surgical excellence rate. Statistical analysis was performed using Revman 5.3 software. A fixed or random effects model was used with odds ratios (OR) for single rate and weighted mean difference (WMD) for continuous variables, and confidence intervals CI was 95%. Results: A total of 6 studies with 515 patients were included in this meta-analysis. Compared with uniportal endoscopy, UBE surgery had a shorter operation time (WMD −12.37, 95%CI −22.15~2.6, P = 0.01). There was no significant difference between groups in VAS scores for low back pain (first day after surgery (WMD 0.27, 95%CI 0.29~0.82, P = 0.35), final follow-up (WMD −0.02, 95%CI 0.1~0.06, P = 0.63), and leg pain first day after surgery (WMD −0.17, 95%CI −0.43~0.09, P = 0.20), final follow-up (WMD 0.03, 95%CI −0.15~0.15, P = 0.51), ODI score (WMD −0.1, 95%CI −0.67~0.47, P = 0.73), complications (OR 0.72, 95%CI 0.37~1.41, P = 0.34), length of hospital stay (WMD −0.06, 95%CI 0.27~0.15, P = 0.56), and rate of excellent operation (OR 1.32, 95%CI 0.69~2.53, P = 0.56). Conclusion: There is no significant difference in clinical efficacy and complication rate between UBE and single channel endoscopy in the treatment of lumbar stenosis. Compared with the single channel endoscopic group, UBE has a shorter operation time.

神经导航辅助下高血压基底节区脑出血微创穿刺引流的研究现状

高血压脑出血是(hypertensive intracerebral hemorrhage, HICH)神经外科较常见的危急重症,其多发于丘脑、基底节区等部位,有较高的致死率和致残率;目前,微创穿刺引流术因手术创伤小且预后良好在我国HICH治疗中应用广泛,随着医学技术不断发展,目前追求微创、精准、简单、快捷的手术方式,神经导航在高血压脑出血中能精准定位血肿部位和边界,规划手术路线,从而减少手术创伤,在外科手术中应用广泛,本文对神经导航在高血压基底节区脑出血微创穿刺引流进行综述。Hypertensive intracerebral hemorrhage (HICH) is a common critical condition in neurosurgery. It is mostly located in thalamus, basal ganglia, and has a high mortality and disability rate. At present, minimally invasive puncture and drainage is widely used in the treatment of HICH in China due to low surgical trauma and good prognosis. With the continuous development of medical technology, minimally invasive, accurate, simple and fast surgical methods are currently pursued. Neuronavigation can accurately locate the site and boundary of hematoma in hypertensive cerebral hemorrhage and plan surgical routes, thus reducing surgical trauma, and is widely used in surgical operations. This article reviews the minimally invasive puncture drainage of neuronavigation in hypertensive basal ganglia cerebral hemorrhage.

浅析中药药对在干燥综合征的应用

干燥综合征是一个慢性、炎性的自身免疫功能紊乱的疾病,它主要影响人体的外分泌腺,中医上将其归属为“燥痹”。药对作为复方的核心,在减轻患者口干、眼干、乏力等临床症状及减少不良反应具有较好的效果。本文选取了养阴润燥的沙参–麦冬,活血化瘀的桃仁–红花,益气养阴的人参–五味子,清热祛湿的生地黄–黄芩,滋阴疏肝的白芍–柴胡等药对,探究它们治疗干燥综合征的功效和临床应用,为临床诊疗本病拓宽新思路。Sjogren’s syndrome is a chronic, inflammatory autoimmune disorder, which mainly affects the exocrine glands of the human body, and is classified as “dryness” in Chinese medicine. As the core of the compound, drug pair has a good effect in alleviating clinical symptoms such as dry mouth, dry eyes, fatigue and reducing adverse reactions. In this paper, we selected a variety of medicine pairs, such as salophiopogon for nourishing Yin and moistening dryness, peach kernel and safflower for promoting blood circulation and removing blood stasis, ginseng and schisandra for nourishing qi and Yin, Radix rehmanniae Radix Baicalensis for clearing heat and dampness, Radix Paeoniae Radix bupleurum for nourishing Yin and soothing liver, to explore their efficacy and clinical application in the treatment of Sjogren’s syndrome, and broaden new ideas for clinical diagnosis and treatment of this disease.

冠心病患者恐动症评估工具及干预对策的研究进展

冠心病患者恐动症作为一种常见的心理障碍,对患者的生活质量和治疗效果产生负面影响。本文旨在探讨冠心病患者恐动症评估工具及干预措施的研究进展。总结了现有研究成果,分析了存在的不足之处,并展望了未来研究方向和发展趋势,旨在为冠心病患者恐动症的早期诊断和有效干预提供理论支持和实践指导。As a common psychological disorder in patients with coronary heart disease, kinetophobia has a negative impact on patients’ quality of life and treatment results. The purpose of this paper is to discuss the research progress of the assessment tools and intervention measures of kinetophobia in patients with coronary heart disease. This paper summarizes the existing research results, analyzes the shortcomings, and looks forward to the future research direction and development trend, aiming at providing theoretical support and practical guidance for the early diagnosis and effective intervention of kinetophobia in patients with coronary heart disease.

基于阴虚论治甲状腺功能亢进症

甲状腺功能亢进症(Hyperthyroidism)是由于甲状腺腺体功能异常增强释放大量的甲状腺素而致机体代谢增强的一种甲状腺疾病,归属于中医“瘿病”的范畴。本病的治疗,立足于中医的整体观念,将药物和人的体质综合考虑,多从“阴虚”论治本病,以滋阴为治疗原则,辅予泻火、潜阳、息风等治疗本病,可有效地改善症状,提高临床疗效,缩短治疗过程。查阅中国知网(CNKI数据库)近五年相关文献,着眼于阴虚理论,论述甲亢的病因病机、治疗原则及中医药治疗本病的研究进展,以期为中医治疗甲亢提供新的思路。Hyperthyroidism is a kind of thyroid disease due to the abnormal function of the thyroid gland and the release of a large amount of thyroxine, which leads to the enhancement of body metabolism, belonging to the category of “gall disease” in Chinese medicine. The treatment of the disease, based on the overall concept of traditional Chinese medicine, the comprehensive consideration of drugs and people’s physique, more from the “Yin deficiency” of the treatment of the disease, to nourish the Yin as the principle of treatment, auxiliary fire, Yang, wind and other treatment of the disease, can effectively improve symptoms, improve clinical efficacy, shorten the treatment process. Refer to the relevant literature of China National Knowledge Network (CNKI database) in the past five years, focusing on the theory of Yin deficiency, this paper discusses the etiology, pathogenesis, treatment principle and research progress of the treatment of hyperthyroidism with traditional Chinese medicine, in order to provide new ideas for Chinese medicine treatment of hyperthyroidism.

复方石斛消渴颗粒联合二甲双胍西格列汀治疗气阴两虚型2型糖尿病回顾性临床分析

目的:回顾性分析院内制剂复方石斛消渴颗粒联合二甲双胍西格列汀治疗气阴两虚型2型糖尿病(T2DM)的临床效果。方法:收集2020年11月至2024年4月于福建中医药大学附属第二人民医院治疗,诊断为气阴两虚证,T2DM的患者80例,对照组和观察组各40例,对照组给予二甲双胍西格列汀,观察组给予复方石斛消渴颗粒联合二甲双胍西格列汀联合治疗,比较两组患者治疗30 d后中医证候、空腹血糖水平(FBG)指标的改善情况;部分患者佩戴血糖监测传感器连续动态监测血糖,记录24 h葡萄糖目标范围内时间、葡萄糖高于目标范围时间、葡萄糖低于目标范围内时间和平均血糖,比较治疗前和治疗三个月两组上述指标的差异。结果:治疗后,观察组患者各项中医证候积分均低于对照组,差异具有统计学意义(P Objective: To retrospectively analyze the clinical effect of compound Dendrobium thirst elimination granules combined with metformin and sitagliptin composite preparation in the treatment of type 2 diabetes mellitus (T2DM) patients with Qi Yin Deficiency. Methods: Treatment at the Second Affiliated Hospital of Fujian University of Traditional Chinese Medicine from November 2020 to April 2024, The diagnosis of qi and Yin two deficiency syndrome, In 80 patients with T2DM, 40 cases each in the control and observation group. The control group was given metformin sitagliptin, the observation group received a combination of compound Dendrobium dequenching granules with metformin sitagliptin. Compare the improvement of TCM syndrome and fasting blood glucose level (FBG) after 30 d of treatment;some patients wear blood glucose monitoring sensors to continuously and dynamically monitor blood glucose, record time in 24 h glucose target range, glucose above target range time, glucose below target range time and mean blood glucose, compare the above indicators before and three months of treatment. Results: After treatment, the TCM syndrome scores of the patients in the observation group were lower than those of the control group, and the difference was statistically significant (P < 0.05);FBG was lower in the observation group, the difference was statistically significant (P < 0.05);the baseline was consistent of two samples before the treatment, After three months of treatment, patients in the observation group had greater glucose reduction and no lower glucose values than the target range, and the glucose volatility was less and more stable. Conclusion: T2DM patients treated with compound Dendrobium granules and metformin sitagliptin could hypoglycemic action and regulate the imbalance of body between Yin and Yang to improve the TCM syndrome.

甲状腺疾病与2型糖尿病的关联

甲状腺疾病和2型糖尿病是临床上最常见的两种内分泌疾病,二者之间的关系也一直备受关注。国内外多项研究表明两者之间存在一定的相关性。因此,为了更好地了解这两种常见疾病之间的联系,本文就2型糖尿病与甲状腺功能亢进症,甲状腺功能减退症及甲状腺结节这三大常见甲状腺疾病之间的发病联系作一综述。

肠造口患者出院准备度及其影响因素的研究进展

本文全面回顾了近年来关于肠造口患者的出院准备度及其影响因素的研究进展,目的是通过对现有研究成果的总结,为肠造口患者制定更为高效的出院管理策略,并提供个性化的临床照护,从而为临床实践提供坚实的理论基础和实践建议。目前关于肠功能恢复状况与疾病严重程度之间的关系的报道较多,但对于其具体机制缺乏深入了解。本研究通过对国内外相关文献检索和分析,深入探讨了肠造口患者出院准备度的评估方法、当前研究现状、影响因素及相应的干预措施,并在文末给出了结论和未来展望。This paper comprehensively reviews the recent research progress on discharge readiness of enterostomy patients and its influencing factors, aiming to develop more efficient discharge management strategies for enterostomy patients and provide personalized clinical care through the summary of existing research results, so as to provide a solid theoretical basis and practical recommendations for clinical practice. At present, there are many reports about the relationship between intestinal function recovery and disease severity, but the specific mechanism is not well understood. Through the search and analysis of relevant literature at home and abroad, this study deeply discussed the evaluation methods, current research status, influencing factors and corresponding intervention measures for discharge readiness of enterostomy patients, and provided conclusions and future prospects at the end of the paper.

卵巢成熟性囊性畸胎瘤恶变为卵巢鳞状细胞癌1例

卵巢成熟性囊性畸胎瘤(ovarian mature cystic teratoma, OMCT)是最常见的卵巢生殖细胞肿瘤,约占卵巢肿瘤的10%至25%。其恶变率相对较低,仅为1.8%。其中,卵巢成熟性囊性畸胎瘤的鳞状细胞癌(squamous cell carcinoma arising from mature cystic teratoma, SCC-MCT)在临床上极为罕见,并且缺乏特异性或典型的症状。影像学检查结果与MCT类似,使得早期鉴别变得困难。该疾病诊断主要依赖于组织学检查,部分患者在被发现时已处于晚期,且术后放化疗的疗效仍不明确。然而,根据血清学指标及宫颈HPV筛查,有助于早期发现、诊断和治疗卵巢MCT。本文章结合国内外相关文献,探讨卵巢成熟性囊性畸胎瘤恶变的临床症状、诊断方法、治疗策略及预后情况。Ovarian mature cystic teratoma (OMCT) is the most common germ cell tumor of the ovary, accounting for about 10% to 25% of ovarian tumors. The rate of malignancy is relatively low, only 1.8%. squamous cell carcinoma arising from mature cystic teratoma (SCC-MCT) is clinically extremely rare and lacks specific or typical symptoms. Imaging findings are similar to those of MCT, making early identification difficult. Diagnosis of the disease is mainly dependent on histological examination, and some patients are in advanced stage at the time of detection, and the efficacy of postoperative radiotherapy and chemotherapy is still unclear. However, screening based on serological indicators and cervical HPV can help in the early detection, diagnosis and treatment of ovarian MCT. In this paper, we discuss the clinical symptoms, diagnosis, treatment strategy and prognosis of malignant transformation of mature cystic teratoma of ovary.

ESRD腹膜透析患者认知障碍相关因素研究进展

鉴于认知障碍已严重影响终末期肾脏病腹膜透析患者的生活质量及存活率,现已成为严重的并发症之一。本文旨在从流行病学、发病机制及影响因素等方面综述终末期肾脏病腹膜透析患者认知障碍的研究进展,以期为临床工作与研究提供参考。

“心–肺–血管”联合超声辅助诊断高危肺栓塞1例

重症肺栓塞是临床中比较凶险的疾病,病因复杂多样,其中以肺血栓栓塞最为常见,其栓子大多来源与下肢静脉,以肺循环和呼吸功能障碍为主的临床表现,死亡率很高,是许多地区和国家心血管死亡的第三大原因,漏诊率和误诊率均高,且预后较差。本文结合1例肺栓塞病例资料,分析了联合“心–肺–血管”超声对急性肺栓塞的早期诊断的重要性,提高该类疾病的早期识别及鉴别,对挽救患者生命及改善预后至关重要。Severe pulmonary embolism is a relatively dangerous disease in clinical practice, with complex and diverse causes. Among them, pulmonary thromboembolism is the most common, and its emboli mostly originate from lower limb veins. Clinical manifestations mainly include pulmonary circulation and respiratory dysfunction, with a high mortality rate. It is the third leading cause of cardiovascular death in many regions and countries, with high rates of missed diagnosis and misdiagnosis, and a poor prognosis. This article combines data from a case of pulmonary embolism to analyze the importance of combining “Cardio-Pulmonary-Vascular” ultrasound in the early diagnosis of acute pulmonary embolism. Improving the early identification and differentiation of this type of disease is crucial for saving patient lives and improving prognosis.