Modeling of Mechanisms Providing the Overall Control of Human Circulation

Multiple humoral and nervous mechanisms,each influencing the cardiovascular system(CVS)with its specific dynamics and power,had been evolutionarily saved both in animals and in human organisms.Most of such mechanisms are considered to be controllers of CVS’s function,but there is no concept clearly explaining the interaction of global and local controllers in intact human organisms under physiological or pathological conditions.Methodological and ethical constraints create practically insuperable obstacles while experiments on animals mainly concern artificial situations with certain switched-of mechanisms.Currently,mathematical modeling and computer simulations provide the most promising way for expanding and deepening our understanding of regulators’interactions.As most of CVS’s models describe only partial control mechanisms,a special model(SM)capable of simulating every combination of control mechanisms is encouraged.This paper has three goals:i)to argue the uncial modeling concept and its physiological basis,ii)to describe SM,and iii)to give basic information about SM’s test research.SM describes human hemodynamics,which is under influence of arterial baroreceptor reflexes,peripheral chemoreceptor reflexes,central(cRAS)and local(lRAS)renin-angiotensin systems,local ischemia,and autoregulation of total brain flow.SM,performed in form of special software(SS),is tested under specific endogenous and/or exogenous alterations.The physiologist using SS can easily construct the desirable configuration of regulator mechanisms,their actual state,and scenarios of computer experiments.Tests illustrated the adequateness of SM,are the first step of SM’s research.Nuances of the interaction of modeled regulator mechanisms have to be illustrated in special publications.

Extracellular Vesicles and Their Significance in COVID-19

Over the last few years,there is huge scientific attention towards the research related to Extracellular Vesicles(EVs),because of their unique property of inter cellular communications and effective biological significance in diagnosis and therapy[1].Extracellular Vesicles are lipid bilayer membrane bound biological entity,which contains different bioactive compounds(cargoes)such as microRNAs(miRNAs),mRNAs,proteins,and lipids.Based on their origin and size,EVs have been categorized into three different types(a)Exosomes(40 nm-150 nm)are smallest EVs,which are synthesized by endocytic pathways in the cells and secreted in extracellular space through exocytosis process,(b)Microvesicles are secreted from direct budding off plasma membranes and their size varying from 50 nm to 1000 nm and,(c)Apoptotic bodies are formed during apoptotic cell death process and respectively larger in size>1000 nm[1-3].EVs have been identified using different markers,that includes tetraspanins proteins(CD9,CD63,CD81,and CD83),endosomal sorting complexes required for transport(TSG101,Alix),heat shock proteins(Hsp60,Hsp70,Hsp90),and Rab proteins(RAB27a/b)[1].

The Historical Changes in Chengde’s Transportation and Its Impact on Urban Development

Transportation has played an indispensable role in driving urban development from ancient times to the present.This paper aims to explore the historical evolution of transportation in Chengde and examine the influence of transportation factors on the city's functions from different perspectives.The research reveals that Chengde's urban development has undergone four stages:natural villages before the Liao Dynasty,urban construction from the Liao Dynasty to the Ming Dynasty,urban development from the early to middle Qing Dynasty,and the present era after the reform and opening-up.The study results demonstrate that Chengde's transportation development has undergone significant transformations.It has not only provided essential support for various aspects such as politics,religion,culture,economy,and military during the Qing Dynasty,but also served as a vital guarantee for modern economic development,tourism,arts,and environmental protection.

Application of Mianzhu New Year Painting Art Style in Children’s Picture Books

This paper analyzes the attraction of children's language learning and literacy through the collation of Chinese Mianzhu New Year's Paintings art style,analyzes the attraction of children's language learning and literacy through the reading of early children's New Year's Paintings art style picture books,summarizes the use of pre-school children's favorite picture book survey reports and data,and analyzes the case of the excellent picture book design that has won awards for integrating the Chinese traditional art style,and the result shows that Mianzhu New Year's Paintings art style has great potential to be explored in the field of picture books.The results show that Mianzhu Nianhua art style in the field of picture books has great potential to be explored,and its artistic characteristics have strong extensibility and integration,and the use of saturated,bright colors combined with children's favorite picture book themes will be more attractive to children to read picture books.This study provides a new design reference for the integration of traditional Chinese art styles with children's picture books,which can enhance children's language learning and literacy skills while promoting the traditional Chinese art of Mianzhu New Year's Paintings.

An Exploration of Domestic Cats’ Domestication History in Ancient Egypt and China

Domestic cats are common pets in today's society and have received love from people all over the world.In world history,there are so many records of domestic cats in various cultures.During the long domestication history,the role and status of the domestic cat in human society have changed a lot and many literary and artistic works have been done for it.Among the various records,Ancient Egypt and China are both characterized by early domestication origins and rich historical records.At the same time,despite the similarities in the role played by the domestic cat in both cultures,there are many differences.These differences,similarities,and concrete reasons not only reflect the many historical similarities and differences between the two cultures,but also reflect the influence of different social contexts on the domestication process of animals,which is a topic worthy of discussion in anthropology,sociology,and genetics.

A Study of Creative Imagery in Public Service Posters Based on Design Cultural Codes Theory

This study,grounded in design culture code theory,rigorously explores the multifaceted impact of visual imagery on poster design.Uniting theory with practicality,it dissects the strategic,semiotic,and technical aspects of poster creation,illuminating how visual elements are strategically employed,convey nuanced meanings,and adhere to design principles.Notably,it scrutinizes the adaptability of these strategies across diverse socio-cultural contexts.The study enriches our comprehension of how visual choices endow posters with significance and emotional resonance.Furthermore,it contributes novel insights into the technical intricacies of visual design principles.By synthesizing theory and practice,with an emphasis on cross-cultural adaptability,this study advances our understanding of how visual imagery influences strategic,meaningful,and technical dimensions in poster design.It holds implications for design practitioners and offers inspiration for future research in this field.In humility,it contributes to the existing body of knowledge while paving the way for further exploration in the discipline.

A Brief Analysis of the Background Music of the Film Changjin Lake

The background music in film and television works plays an irreplaceable role in revealing the theme of film and television drama,rendering the atmosphere of film and television drama,deepening the depiction of characters and the expression of emotions and emotions.This paper gives a comprehensive introduction to the development logic and emotional context of the film Changjin Lake.And the film long jin lake appear impressive score plot and theme and episode is analyzed,aimed at the analysis of theme,background music,episode,explore its important role in the movie over and over to excavate the scene of the movie music connotation and the key to the background music for the film and the shaping of image.

Female Look Anxiety - A Study of the Commodification of the Body of Girls in Plastic Surgery Circles

Through this research study,by examining the issue of the commodification of plastic surgery circle girls'bodies as a whole,we discover the historical and contemporary contextual factors that have led to this problem and the impacts it generates in our current environment.Exploring the causes and development of this issue can,to some extent,aid women in breaking free from the position of being objectified,thus mitigating appearance anxiety.It is advised that women avoid becoming overly immersed in the transformative effects of medical cosmetic procedures and work towards liberating themselves from the commodification of their bodies.

Preface

Advances in Humanities Research(AHR)is an international peer reviewed journal which is focused on exploring important and emerging topics on various perspectives of linguistics,literature,art,history and philosophy.The journal publishes only original articles that are research-oriented from a wide variety of methodological and disciplinary perspectives concerning humanities issues.The key objectives of the journal are the following:To foster and enhance research activities that advance knowledge in linguistics,literature,art,history and philosophy.

A Review of Conformity Behavior Studies in Social Networks

This article contains research on the development of conformity behaviors in social networks,in which individuals change their ideas or behavior in keeping with a group.Social networks originated from the experiment called small world phenomenon,which concluded that in the United States,the average distance between one person to another person is six persons,which can also be called Six Degrees of Separation,proving the existence of a social network of people.Conformity behavior refers to individuals changing their behavior under real or imagined group pressure to adapt to the behavioral responses of others.conformity behavior in social networks is mainly studied through questionnaires,websites,and simulation modeling.

Femme Fatale in French Film Noir

The term film noir was coined by two French film critics Borde and Chaumenton in 1956 to describe American detective stories mode in the 1940s.Noir films were seen as a counter-cultural movement within Hollywood at that time,and the French new wave continued this feature in the 1960s.Therefore,the term noir itself connects the Frenchness and Americanness.This paper tends to map out the film noir sensibilities in French content through unfolding the characteristics of femme fatale in two French noir films Jean-Luc Godard’s A bout de souffle(Breathless)(1960)and Jean-Jacques Beineix’s Diva(1981).

Preface

Advances in Humanities Research(AHR)is an international peer reviewed journal which is focused on exploring important and emerging topics on various perspectives of linguistics,literature,art,history and philosophy.The journal publishes only original articles that are research-oriented from a wide variety of methodological and disciplinary perspectives concerning humanities issues.The key objectives of the journal are the following:To foster and enhance research activities that advance knowledge in linguistics,literature,art,history and philosophy.

Post-war British Cinema: Constructing an Imagined Community Through National Cinema

Benedict Anderson’s masterpiece Imagined Communities:Reflections on the Origin and Spread of Nationalism has influenced the discipline of national cinema greatly since its publication.This paper aims to decode British national cinema from the late 1940s to early 1960s to rediscover the situation of British society at that time through Anderson’s conception of“imagined communities”.Through reading closely on two representative British films A Matter of Life and Death(Emeric Pressburge,1946)and Saturday Night and Sunday Morning(Karel Reisz,1960),the paper portrays the great changes happened in Britain from the end of the the Second World War to the beginning of the 1960s.