目的系统评价“补虚化浊法”中药联合抗血管内皮生长因子(VEGF)治疗湿性年龄相关性黄斑变性(wAMD)的临床疗效。方法检索PubMed、Web of Science、Embase、中国知网、万方、维普、中国生物医学文献数据库中应用“补虚化浊法”中药治疗wAM...目的系统评价“补虚化浊法”中药联合抗血管内皮生长因子(VEGF)治疗湿性年龄相关性黄斑变性(wAMD)的临床疗效。方法检索PubMed、Web of Science、Embase、中国知网、万方、维普、中国生物医学文献数据库中应用“补虚化浊法”中药治疗wAMD的随机对照试验文献,检索时间为建库至2023年5月31日,对文献按照纳入标准与排除标准进行筛选和数据录取,采用Cochrane软件评价文献质量,采用RevMan 5.4软件进行统计分析。结果共纳入13项研究,包括患者1,002例(1,041只眼),其中采用“补虚化浊法”联合抗VEGF治疗的治疗组501例(523只眼),单纯抗VEGF治疗的对照组501例(518只眼)。治疗组在提高国际标准视力[MD=0.100,95%CI(0.050,0.140),Z=4.310,P=0.000]、LogMAR视力[MD=-0.080,95%CI(-0.110,-0.050),Z=5.560,P=0.000]、视力总有效率[OR=2.070,95%CI(1.280,3.340),Z=2.970,P=0.000]、降低黄斑中心凹厚度[MD=-19.130,95%CI(-24.940,-13.310),Z=6.450,P=0.000]、提高荧光渗漏吸收率[OR=4.910,95%CI(2.870,8.400),Z=5.800,P=0.000]、提高临床总有效率[OR=3.810,95%CI(1.990,7.310),Z=4.030,P=0.000]方面优于对照组,差异均有统计学意义。结论“补虚化浊法”中药联合抗VEGF治疗wAMD疗效优于单纯抗VEGF治疗。展开更多
高校安全事故发生频率明显增加,发生类型更为复杂,其中的重要原因在于高校内部保卫职能的虚化。从历史发展看,高校保卫部门逐渐从公安派出机关转化为内部保卫部门,其所拥有的管理权力随着时间的推移逐渐减少,但其面临的任务日趋复杂,出...高校安全事故发生频率明显增加,发生类型更为复杂,其中的重要原因在于高校内部保卫职能的虚化。从历史发展看,高校保卫部门逐渐从公安派出机关转化为内部保卫部门,其所拥有的管理权力随着时间的推移逐渐减少,但其面临的任务日趋复杂,出现明显的权责不匹配与安全保卫队伍的弱化。因而目前高校安全保卫部门的职能出现了较为明显的虚化。为扭转这一局面,需要加强保卫工作的顶层设计、加强保卫队伍的建设工作、提高安全综合治理的能力。The occurrence frequency of safety accidents in colleges and universities has increased significantly, and the occurrence types are more complex. The important reason lies in the weakness of the internal security functions in colleges and universities. From the perspective of historical development, the security departments of colleges and universities have gradually transformed from the public security organizations to the internal security departments. Their management power gradually decreases, but the tasks are increasingly complex. So, there is an obvious mismatch between power and responsibilities and weakening of the security team. In general, the functions of the security department in colleges and universities gradually appear weakness. In order to response to this situation, it is necessary to perfect the top-level design of the security work, strengthen the construction of the security team, and improve the ability of comprehensive security management.展开更多
文摘目的系统评价“补虚化浊法”中药联合抗血管内皮生长因子(VEGF)治疗湿性年龄相关性黄斑变性(wAMD)的临床疗效。方法检索PubMed、Web of Science、Embase、中国知网、万方、维普、中国生物医学文献数据库中应用“补虚化浊法”中药治疗wAMD的随机对照试验文献,检索时间为建库至2023年5月31日,对文献按照纳入标准与排除标准进行筛选和数据录取,采用Cochrane软件评价文献质量,采用RevMan 5.4软件进行统计分析。结果共纳入13项研究,包括患者1,002例(1,041只眼),其中采用“补虚化浊法”联合抗VEGF治疗的治疗组501例(523只眼),单纯抗VEGF治疗的对照组501例(518只眼)。治疗组在提高国际标准视力[MD=0.100,95%CI(0.050,0.140),Z=4.310,P=0.000]、LogMAR视力[MD=-0.080,95%CI(-0.110,-0.050),Z=5.560,P=0.000]、视力总有效率[OR=2.070,95%CI(1.280,3.340),Z=2.970,P=0.000]、降低黄斑中心凹厚度[MD=-19.130,95%CI(-24.940,-13.310),Z=6.450,P=0.000]、提高荧光渗漏吸收率[OR=4.910,95%CI(2.870,8.400),Z=5.800,P=0.000]、提高临床总有效率[OR=3.810,95%CI(1.990,7.310),Z=4.030,P=0.000]方面优于对照组,差异均有统计学意义。结论“补虚化浊法”中药联合抗VEGF治疗wAMD疗效优于单纯抗VEGF治疗。
文摘高校安全事故发生频率明显增加,发生类型更为复杂,其中的重要原因在于高校内部保卫职能的虚化。从历史发展看,高校保卫部门逐渐从公安派出机关转化为内部保卫部门,其所拥有的管理权力随着时间的推移逐渐减少,但其面临的任务日趋复杂,出现明显的权责不匹配与安全保卫队伍的弱化。因而目前高校安全保卫部门的职能出现了较为明显的虚化。为扭转这一局面,需要加强保卫工作的顶层设计、加强保卫队伍的建设工作、提高安全综合治理的能力。The occurrence frequency of safety accidents in colleges and universities has increased significantly, and the occurrence types are more complex. The important reason lies in the weakness of the internal security functions in colleges and universities. From the perspective of historical development, the security departments of colleges and universities have gradually transformed from the public security organizations to the internal security departments. Their management power gradually decreases, but the tasks are increasingly complex. So, there is an obvious mismatch between power and responsibilities and weakening of the security team. In general, the functions of the security department in colleges and universities gradually appear weakness. In order to response to this situation, it is necessary to perfect the top-level design of the security work, strengthen the construction of the security team, and improve the ability of comprehensive security management.
