2019年的新型冠状病毒感染(coronavirus disease 2019,COVID-19)大流行给医疗系统带来了巨大的挑战,其中一些挑战将导致变革性的变化。在当前COVID-19已经被控制但又时常复发的事实下,需要重症医学科(intensive care unit,ICU)做出相应...2019年的新型冠状病毒感染(coronavirus disease 2019,COVID-19)大流行给医疗系统带来了巨大的挑战,其中一些挑战将导致变革性的变化。在当前COVID-19已经被控制但又时常复发的事实下,需要重症医学科(intensive care unit,ICU)做出相应的调整以适应疫情常态化时代,包括ICU必须准备好应对患者激增,防止个人防护设备、ICU设备、消耗品和药品短缺,以及重视实施更合理安全的病房规划,预先进行重症专业人才的培养及储备,进行现有医护人员基础操作的培训和预先存在的ICU分诊和远程控制等。COVID-19大流行提醒我们,除了已有的核心责任之外,还应致力于改进不足,通过提前应对这些挑战,为未来的患者提供更好的诊疗。展开更多
Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research and updates. In this sense, the objective of the present article was to review stu...Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research and updates. In this sense, the objective of the present article was to review studies on the role of wild animals as reservoirs and/or dispersers of etiological agents of human infectious diseases in order to compile data on the main wild animals and etiological agents involved in zoonotic outbreaks. A systematic review was carried out using PRISMA guidelines, using the PubMed, Scopus and SciELO platforms as data banks. The descriptors used were "zoonosis", "human infectious diseases" and "wild animals". The results show that wild animals(mainly bats, birds and primates) play an important role in the dissemination of etiological agents(mainly viruses, as a new coronavirus called 2019 Novel Coronavirus) in extensive geographic regions. Moreover, these wild animal organisms can act as the site for essential biotic synergy among several pathogenic microorganisms, promoting a higher rate of adaptation, mutation and even genetic recombination, with consequent stimulation of new strains and subtypes, inducing new infectious agents with unknown virulent potential. In conclusion, the monitoring of these diseases and adequate preparation for possible epidemics and pandemics are fundamental conditions for the mitigation of their future impact. The zoonotic threat of these etiological agents and the impact on public health can be enormous as shown by the ongoing epidemic of 2019 novel coronavirus(2019-nCoV) infections.展开更多
文摘2019年的新型冠状病毒感染(coronavirus disease 2019,COVID-19)大流行给医疗系统带来了巨大的挑战,其中一些挑战将导致变革性的变化。在当前COVID-19已经被控制但又时常复发的事实下,需要重症医学科(intensive care unit,ICU)做出相应的调整以适应疫情常态化时代,包括ICU必须准备好应对患者激增,防止个人防护设备、ICU设备、消耗品和药品短缺,以及重视实施更合理安全的病房规划,预先进行重症专业人才的培养及储备,进行现有医护人员基础操作的培训和预先存在的ICU分诊和远程控制等。COVID-19大流行提醒我们,除了已有的核心责任之外,还应致力于改进不足,通过提前应对这些挑战,为未来的患者提供更好的诊疗。
基金support received from the Faculdade Dinamica do Vale do Piranga(FADIP),Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq)and Fundacao de Amparo a Pesquisa do Estado de Minas Gerais(FAPEMIG).
文摘Infectious diseases continue to impose unpredictable burdens on global health and economies, a subject that requires constant research and updates. In this sense, the objective of the present article was to review studies on the role of wild animals as reservoirs and/or dispersers of etiological agents of human infectious diseases in order to compile data on the main wild animals and etiological agents involved in zoonotic outbreaks. A systematic review was carried out using PRISMA guidelines, using the PubMed, Scopus and SciELO platforms as data banks. The descriptors used were "zoonosis", "human infectious diseases" and "wild animals". The results show that wild animals(mainly bats, birds and primates) play an important role in the dissemination of etiological agents(mainly viruses, as a new coronavirus called 2019 Novel Coronavirus) in extensive geographic regions. Moreover, these wild animal organisms can act as the site for essential biotic synergy among several pathogenic microorganisms, promoting a higher rate of adaptation, mutation and even genetic recombination, with consequent stimulation of new strains and subtypes, inducing new infectious agents with unknown virulent potential. In conclusion, the monitoring of these diseases and adequate preparation for possible epidemics and pandemics are fundamental conditions for the mitigation of their future impact. The zoonotic threat of these etiological agents and the impact on public health can be enormous as shown by the ongoing epidemic of 2019 novel coronavirus(2019-nCoV) infections.
