Key technologies for dual high-k and dual metal gate integration

The key technologies for the dual high-k and dual metal gate, such as the electrical optimization of metal insert poly-Si stack structure, the separating of high-k and metal gate of n/pMOS in different regions of the wafer, and the synchronous etching of n/pMOS gate stack, are successfully developed. First, reasonable flat-band voltage and equivalent oxide thickness of pMOS MIPS structure are obtained by further optimizing the HfSiAlON dielectric through incorporating more Al-O dipole at interface between HfSiAlON and bottom SiOx. Then, the separating of high-k and metal gate for n/pMOS is achieved by SC1（NH4OH：H2O2：H2O = 1 ： 1 ： 5） and DHF-based solution for the selective removing of n MOS TaN and Hf Si ON and by BCl3-based plasma and DHF-based solution for the selective removing of pMOS TaN/Mo and HfSiAlON.After that, the synchronous etching of n/pMOS gate stack is developed by utilizing optimized BCl3/SF6/O2/Ar plasma to obtain a vertical profile for TaN and TaN/Mo and by utilizing BCl3/Ar plasma combined with DHF-based solution to achieve high selectivity to Si substrate. Finally, good electrical characteristics of CMOS devices, obtained by utilizing these new developed technologies, further confirm that they are practicable technologies for DHDMG integration.

Role of high-dose amoxicillin dual therapy for Helicobacter pylori eradication in an Irish cohort:A prospective study

Helicobacter pylori(H.pylori)infections may cause chronic gastritis,peptic ulcer disease,gastric cancers,and other conditions outside of the gastrointestinal tract.Hence,it is important to diagnose and treat it early.H.pylori is resistant to certain drugs in traditional eradication therapy,so alternative therapy protocols are needed,such as high-dose amoxicillin dual therapy(HDADT).This article aims to comment on a recent paper by Costigan et al in the World Journal of Clinical Cases.In this study,the authors recruited 139 patients diagnosed with H.pylori,all treated with HDADT.Of these,93 were treatment-naïve and 46 had received at least one alternative treatment in the past.Four weeks after the end of the treatment,the urea breath test was administered to estimate the eradication rate.The total eradication rate was 56%(78/139),62%for the treatment-naïve arm and 43%for the previous treatment arm,thus indicating a lower success rate for the arm that had previously received a different treatment regimen.In conclusion,a therapeutic approach with first-line HDADT may potentially be a better treat-ment,but the results are not sufficient to recommend the use of this regimen in a country with high levels of dual resistance.

Dual antibiotic loaded bone cement in patients at high infection risks in arthroplasty: Rationale of use for prophylaxis and scientific evidence

In view of the demographic changes and projected increase of arthroplasty procedures worldwide,the number of prosthetic joint infection cases will naturally grow.Therefore,in order to counteract this trend more rigid rules and a stricter implementation of effective preventive strategies is of highest importance.In the absence of a"miracle weapon"priorities should lie in evidence-based measures including preoperative optimization of patients at higher infection risks,the fulfilment of strict hygiene rules in the operating theatre and an effective antibiotic prophylaxis regimen.Instead of a"one size fits all"philosophy,it has been proposed to adjust the antibiotic prophylaxis protocol to major infection risks taking into account important patient-and procedure-related risk factors.A stronger focus on the local application mode via use of high dose dual antibioticloaded bone cement in such risk situations may have its advantages and is easy to apply in the theatre.The more potent antimicrobial growth inhibition in vitro and the strong reduction of the prosthetic joint infection rate in risk for infection patients with aid of dual antibiotic-loaded bone cement in clinical studies align with this hypothesis.

Carbon foam with microporous structure for high performance symmetric potassium dual-ion capacitor

A novel carbon foam with microporous structure(CFMS),with the advantages of a simple fabrication process,low energy consumption,large specific surface area and high conductivity,has been prepared by a facile one-step carbonization.In addition,the carbon foam possesses suitable interlayer spacing in short range which is flexible to accommodate the deformation of carbon layer caused by the ion insertion and deinsertion at the charge and discharge state.Furthermore,a low cost carbon-based symmetric potassium dual-ion capacitor(PDIC),which integrates the virtues of potassium ion capacitors and dual-ion batteries,is successfully established with CFMS as both the battery-type cathode and the capacitor-type anode.PDIC displays a superior rate performance,an ultra-long cycle life(90%retention after 10000 cycles),and a high power density of 7800 W kg^-1 at an energy density of 39Whkg^-1.The PDIC also exhibits excellent ultrafast charge and slow discharge properties,with a full charge in just 60 s and a discharge time of more than 3000 s.

Non-enhanced Low-tube-voltage High-pitch Dual-source Computed Tomography with Sinogram Affirmed Iterative Reconstruction Algorithm of the Abdomen and Pelvis

Objective To investigate the image quality, radiation dose and diagnostic value of the low-tube-voltage high-pitch dual-source computed tomography(DSCT) with sinogram affirmed iterative reconstruction(SAFIRE) for non-enhanced abdominal and pelvic scans. Methods This institutional review board-approved prospective study included 64 patients who gave written informed consent for additional abdominal and pelvic scan with DSCT in the period from November to December 2012. The patients underwent standard non-enhanced CT scans(protocol 1) [tube voltage of 120 k Vp/pitch of 0.9/filtered back-projection(FBP) reconstruction] followed by high-pitch non-enhanced CT scans(protocol 2)(100 k Vp/3.0/SAFIRE). The total scan time, mean CT number, signal-to-noise ratio(SNR), image quality, lesion detectability and radiation dose were compared between the two protocols. Results The total scan time of protocol 2 was significantly shorter than that of protocol 1(1.4±0.1 seconds vs. 7.6±0.6 seconds, P<0.001). There was no significant difference between protocol 1 and protocol 2 in mean CT number of all organs(liver, 55.4±6.3 HU vs. 56.1±6.8 HU, P=0.214; pancreas, 43.6±5.9 HU vs. 43.7±5.8 HU, P=0.785; spleen, 47.9±3.9 HU vs. 49.4±4.3 HU, P=0.128; kidney, 32.2±2.3 HU vs. 33.1±2.3 HU, P=0.367; abdominal aorta, 44.8±5.6 HU vs. 45.0±5.5 HU, P=0.499; psoas muscle, 50.7±4.1 HU vs. 50.3±4.5 HU, P=0.279). SNR on images of protocol 2 was higher than that of protocol 1(liver, 5.0±1.2 vs. 4.5±1.1, P<0.001; pancreas, 4.0±1.0 vs. 3.6±0.8, P<0.001; spleen, 4.7±1.0 vs. 4.1±0.9, P<0.001; kidney, 3.1±0.6 vs. 2.8±0.6, P<0.001; abdominal aorta, 4.1±1.0 vs. 3.8±1.0, P<0.001; psoas muscle, 4.5±1.1 vs. 4.3±1.2, P=0.012). The overall image noise of protocol 2 was lower than that of protocol1(9.8±3.1 HU vs. 11.1±3.0 HU, P<0.001). Image quality of protocol 2 was good but lower than that of protocol 1(4.1±0.7 vs. 4.6±0.5, P<0.001). Protocol 2 perceived 229 of 234 lesions(97.9%) that were detected in protocol 1 in the abdomen and pelvis. Radiation dose of protocol 2 was lower than that of protocol 1(4.4±0.4 m Sv vs. 7.3±2.4 m Sv, P<0.001) and the mean dose reduction was 41.4%. Conclusion The high-pitch DSCT with SAFIRE can shorten scan time and reduce radiation dose while preserving image quality in non-enhanced abdominal and pelvic scans.

Microstructures and mechanical properties of C-Mn-Cr-Nb and C-Mn-Si-Nb ultra-high strength dual-phase steels

The microstructures and mechanical properties of C-Mn-Cr-Nb and C-Mn-Si-Nb ultra-high strength dual-phase steels were studied by scanning electron microscopy （SEM）, transmission electron microscopy （TEM）, and tensile test. The results show that Si can promote the transformation of austenite （γ） to ferrite （α）, enlarge the （α＋γ） region, and increase the aging stability of martensite by inhibiting carbide precipitation. Adding Cr leads to the formation of retained austenite and martensite/austenite （M/A） constituents, as well as the decomposi- tion of martensite during the overaging stage. Both of the steels show higher initial strain-hardening rates and two-stage strain-hardening characteristics. The C-Mn-Si-Nb steel shows the higher strain-hardening rate than the C-Mn-Cr-Nb steel in the first stage; however, there is no significant difference in the second stage. Although the tensile strength and elongation of the two steels both exceed 1000 MPa and 15%, respectively, the comprehensive mechanical properties of the C-Mn-Si-Nb steel are superior.

Helicobacter pylori:High dose amoxicillin does not improve primary or secondary eradication rates in an Irish cohort

BACKGROUND Helicobacter pylori(H.pylori)eradication rates have fallen globally,likely in large part due to increasing antibiotic resistance to traditional therapy.In areas of high clarithromycin and metronidazole resistance such as ours,Maastricht VI guidelines suggest high dose amoxicillin dual therapy(HDADT)can be considered,subject to evidence for local efficacy.In this study we assess efficacy of HDADT therapy for H.pylori eradication in an Irish cohort.AIM To assess the efficacy of HDADT therapy for H.pylori eradication in an Irish cohort as both first line,and subsequent therapy for patients diagnosed with H.pylori.METHODS All patients testing positive for H.pylori in a tertiary centre were treated prospectively with HDADT(amoxicillin 1 g tid and esomeprazole 40 mg bid×14 d)over a period of 8 months.Eradication was confirmed with Urea Breath Test at least 4 wk after cessation of therapy.A delta-over-baseline>4%was considered positive.Patient demographics and treatment outcomes were recorded,analysed and controlled for basic demographics and prior H.pylori treatment.RESULTS One hundred and ninety-eight patients were identified with H.pylori infection,10 patients were excluded due to penicillin allergy and 38 patients refused follow up testing.In all 139 were included in the analysis,55%(n=76)were female,mean age was 46.6 years.Overall,93(67%)of patients were treatment-naïve and 46(33%)had received at least one previous course of treatment.The groups were statistically similar.Self-reported compliance with HDADT was 97%,mild side-effects occurred in 7%.There were no serious adverse drug reactions.Overall the eradication rate for our cohort was 56%(78/139).Eradication rates were worse for those with previous treatment[43%(20/46)vs 62%(58/93),P=0.0458,odds ratio=2.15].Age and Gender had no effect on eradication status.CONCLUSION Overall eradication rates with HDADT were disappointing.Despite being a simple and possibly better tolerated regime,these results do not support its routine use in a high dual resistance country.Further investigation of other regimens to achieve the>90%eradication target is needed.

Interaction of Hydrogen and Retained Austenite in Bainite/Martensite Dual-Phase High Strength Steel

The hydrogen trapping phenomena in two bainite/martensite dual-phase high strength steels(U20Si and U20DSi)were investigated by electrochemical permeation technique.The hydrogen diffusivity was calculated from data of permeation delay time,and the diffusion coefficient in U20 Si is far less than that in U20 DSi.Moreover,the hydrogen diffusivity decreases as the volume percent of retained austenite increases.The experiment results show that there are different hydrogen trappings and different volume percents of retained austenite in U20 Si and U20 DSi.The retained austenite is precipitated as films.The trap binding energy for the retained austenite and hydrogen is calculated to be 40.4kJ·mol-1.

Planar Compact Dual-Band Coupled-Line Balun with High Isolation

A planar circuit structure, which is based on three cascaded pairs of coupled lines, an open stub, and an isolation resistor, is proposed in this paper to design a compact dual.band balun with high isolation. This circuit features equal power division with out of phase, all ports matching, high isolation between two outputs, compact structure, and inherent impedance transformation. The closedform design equations are derived based on the traditional transmission.line theory and even.(odd.) mode analysis. A practical dual.band balun, which operates at 0.9/1.8GHz, is designed and fabricated to validate the function of equal power division with out of phase and high isolation between two outputs. The consistency between the simulated and measured results verify the design theory.

3D skeleton nanostructured Ni_3S_2/Ni foam@RGO composite anode for high-performance dual-ion battery

The growing global demands of safe, low-cost and high working voltage energy storage devices trigger strong interests in novel battery concepts beyond state-of-art lithium-ion battery. Herein, a dualion battery based on nanostructured Ni_3S_2/Ni foam@RGO(NSNR) composite anode is developed, utilizing graphite as cathode material and LiPF6-VC-based solvent as electrolyte. The battery operates at high working voltage of 4.2–4.5 V, with superior discharge capacity of ～90 m A h g^(-1) at 100 mA g^(-1), outstanding rate performance, and long-term cycling stability over 500 cycles with discharge capacity retention of ～85.6%. Moreover, the composite simultaneously acts as the anode material and the current collector, and the corrosion phenomenon can be greatly reduced compared to metallic Al anode. Thus, this work represents a significant step forward for practical safe, low-cost and high working voltage dual-ion batteries,showing attractive potential for future energy storage application.

A curve-based material recognition method in MeV dual-energy X-ray imaging system

High-energy dual-energy X-ray digital radiography imaging is mainly used in the material recognition of cargo inspection. We introduce the development history and principle of the technology and describe the data process flow of our system. The system corrects original data to get a dual-energy transparence image. Material categories of all points in the image are identified by the classification curve,which is related to the X-ray energy spectrum. For the calibration of classification curve, our strategy involves a basic curve calibration and a real-time correction devoted to enhancing the classification accuracy. Image segmentation and denoising methods are applied to smooth the image. The image contains more information after colorization. Some results show that our methods achieve the desired effect.

一种分步式Dual slope ADC的研究与设计

介绍了一种分步式Dual slope ADC,并且详细介绍了此结构提出的理论基础、电路的具体结构和仿真结果。该Dual slope ADC的系统时钟为1 MHz,输入电压范围为0.5 V^4.5 V,电源电压为5 V。相对于传统的Dual slope ADC,此分步式Dual slope ADC不但可以达到更高的分辨率,而且弥补了传统的Dual slope ADC的缺点,即对于全集成电路的大分布电容的要求以及高分辨率转换时间过长,使得此新型模数转换器还具有速度快(远远快于双积分ADC的速度)的优点。

高质量发展背景下职业院校“双师型”教师队伍建设:进展、困境及突破路径

“双师型”教师队伍是职业教育高质量发展的关键。通过对“双师型”教师队伍建设现状梳理发现,政策愈发关注“双师型”教师队伍内涵提升,同时也存在教师培养不足、在职教师学历提升遇到瓶颈、高技能人才进入职业院校路径不畅等困境。为此,应建设开放型职业教育教师培养体系,吸引应用型高校加入职教教师培养体系,为在职教师学历提升及高技能人才进入职教教师队伍打开通道,通过产教融合为“双师型”教师队伍的可持续发展提供保障。

Polymeric Hydrogel Nanocapsules: A Thermo and pH Dual-responsive Carrier for Sustained Drug Release

Hydrogel capsules show attractive prospects in drug delivery recently because of high drug loading and sustained release behavior. In this study we reported a simple and convenient route to fabricate poly(acrylic acid)-poly(N-isopropylacrylamide)(PAA-PNIPAm) hydrogel capsules by using hydroxypropylcellulose-poly(acrylic acid)(HPC-PAA) complexes as the templates. The capsules showed a high drug loading(～280% to the weight of capsules) for Doxorubicin hydrochloride. The release of drug from the capsules was responsive to the temperature and p H of the surroundings, showing a low-rate but sustained release behavior favorable for low-toxic and long-term therapy. Together with the convenient preparation, high drug loading, dual responsivity as well as the sustained release feature, it is implied that this polymeric hydrogel capsule might be a promising candidate for new drug carriers.

一种可拓展双输入高增益DC/DC变换器

针对光伏发电系统中光伏电池板集成汇流的需求,提出了一种可拓展双输入高增益DC/DC变换器。该变换器采用了一种新型拓扑结构,可在实现输入输出电压高增益变换的同时降低了开关器件的电压应力。此外,所提变换器还具有可拓展性,可以根据不同的光伏电池板数量和输出电压要求对端口进行扩展,从而降低系统的复杂性和成本。首先详细介绍了所提变换器的拓扑结构,并推导出变换器在不同工作模态下的运行原理。然后,对该变换器的增益特性、开关器件的电压和电流应力、关键器件的参数选择和损耗计算等方面进行了深入的理论分析。最后,搭建了一台输出功率为1 kW的实验样机,并进行了实验测试。实验结果验证了所提变换器理论分析的正确性和可行性。

Research of DP600 high strength steel wheels

Steel has been used as a traditional wheel materials for a long time.Before 1980' s,over 90% wheels were made of steels.Then,the yield strength of wheel steels increased gradually from 240 -350 MPa to 600 MPa or higher.The advanced high strength steels become the main wheel materials.Since 1990's,DP600 has been broadly applied in steel wheels oversea.However,there was little research of application of high strength steel wheels(especially wheel disc) in domestic wheel industrial.In presence, DP600 steel wheel is only developed in FAWSH by using imported CKD.Other domestic steel wheel manufacturers did little work on high strength DP600 wheel discs.Baosteel wheels Co.Ltd.is the first domestic company producing DP600 steel discs and has become the leading company in production of high strength wheel.Because of the high strength of DP600,its formability,springback,and wrinkle have become the keys of the successful application of DP600 steel.In this paper,the metallurgical and mechanical properties are firstly introduced and formation problems of DP600 are described compared to traditional steels.Secondly,FLD analysis has been done.Wrinkle and more springback are recognized.To solve these problems,an optimized solution is designed and the good result is obtained.The test has shown that the fatigue property of steel wheel discs made by DP600 have been greatly improved.

双循环推动高质量就业的传导路径和作用机制——基于结构方程模型的多重中介效应检验

随着新时期我国社会发展主要矛盾的深刻变化,高质量就业成为立足新发展阶段、贯彻新发展理念、构建新发展格局、推进高质量发展的重要抓手。基于《中国统计年鉴》和中国劳动力动态调查2012—2018年四期面板数据,利用结构方程模型(SEM)分析了双循环影响我国高质量就业的传导路径及作用机制。研究发现:内、外循环之间的协调互动可以显著促进高质量就业,其效应贡献率为45.15%;双循环所带来的技术进步、产业结构升级、人力资本积累是推动高质量就业的重要渠道,其效应贡献率为54.85%,其中,技术进步发挥的中介效应最强,贡献率为32.56%,产业结构升级和人力资本积累的贡献率分别为4.84%和5.89%。因此我国要充分依托国内超大规模市场优势,继续推动高水平对外开放,提升双循环的互动水平。同时充分发挥技术进步的“牵引器”、产业结构升级的“助推器”以及人力资本积累的“支撑轴”作用,从政策上支持我国在加快构建双循环新发展格局中更好地同步推动高质量就业。

基于双重介质渗流-应力耦合模型的高压压水试验渗透参数反演

高压压水试验过程中岩体易发生水力劈裂产生裂隙,岩体内部孔隙、裂隙双重导水,渗流场和应力场相互作用,导致岩体渗透参数的时空变异性。基于高压压水试验反演渗透参数需考虑双重介质渗流-应力耦合作用下产生裂隙前后渗透系数的变化规律,利用渗流-应力耦合数值模型结合工程现场高压压水试验数据进行参数反演,计算得到不同压力阶段下灰岩岩体渗透率。主要结论如下:发生水力劈裂前,随着注液压力的增大,渗透率及孔隙水压力在不同压力阶段之间分界明显,渗透率反演值与规程公式计算值相近;发生水力劈裂后,岩体渗透率增大约2倍,孔隙介质渗透率和通过的流量出现陡减现象。

电感耦合等离子体质谱双模式法测定高纯石英中痕量锂和磷

采用氢氟酸预先分解样品,再以HF-HNO_(3)混合酸进行微波密闭消解,实现4N级高纯石英砂中包含包裹体等杂质的完全溶解;在No gas模式下采集轻质量同位素^(7)Li的质谱信号,以He的碰撞效应来减弱多原子离子的动能,利用动能歧视(KED)效应来消除多原子离子对^(31)P的质谱信号干扰,建立起一次进样、两种模式切换采集信号的电感耦合等离子体质谱分析法,同时测定高纯石英样品中痕量锂、磷的含量。综合选择^(6)Li和^(103)Rh分别作为^(7)Li和^(31)P的内标校正元素,^(7)Li和^(31)P工作曲线的相关性良好,锂和磷的方法检出限分别为0.0029和0.0036 mg·L^(-1);实际石英样品锂和磷的平均加标回收率分别为102.4%和97.87%。监控标准样品的实测值与标准参考值相一致。

“双碳”目标下河南高耗能制造业数字化转型路径分析

在碳峰值、碳中和的目标下,推动数字赋能工业绿色低碳转型势在必行。针对当前“双高”背景下高耗能制造业的发展现状及困境展开分析,并以实地调研诊断相关高耗能制造业企业数字化转型发展情况为基础,探索“双碳”背景下高耗能制造业企业数字化转型的路径,从自动化到数字化到网络化到智能化全面的转型,自下而上涉及智能装备、智能单元、智能产线、智能工厂及智能公司建设等方面。