CARE FOR THE ELDERLY Sanlian Lifeweek 25 November 2024 China is coping with a rapidly aging population.O!cial data shows that the number of people aged 60 and older was almost 297 million in 2023,comprising 21.1 perce...CARE FOR THE ELDERLY Sanlian Lifeweek 25 November 2024 China is coping with a rapidly aging population.O!cial data shows that the number of people aged 60 and older was almost 297 million in 2023,comprising 21.1 percent of the total population.This proportion is expected to exceed 30 percent by 2035.展开更多
Many countries throughout the world have experienced large earthquakes,which cause building damage or collapse.After such earthquakes,structures must be inspected rapidly to judge whether they are safe to reoccupy.To ...Many countries throughout the world have experienced large earthquakes,which cause building damage or collapse.After such earthquakes,structures must be inspected rapidly to judge whether they are safe to reoccupy.To facilitate the inspection process,the authors previously developed a rapid building safety assessment system using sparse acceleration measurements for steel framed buildings.The proposed system modeled nonlinearity in the measurement data using a calibrated simplified lumped-mass model and convolutional neural networks(CNNs),based on which the buildinglevel damage index was estimated rapidly after earthquakes.The proposed system was validated for a nonlinear 3D numerical model of a five-story steel building,and later for a large-scale specimen of an 18-story building in Japan tested on the E-Defense shaking table.However,the applicability of the safety assessment system for reinforced concrete(RC)structures with complex hysteretic material nonlinearity has yet to be explored;the previous approach based on a simplified lumpedmass model with a Bouc-Wen hysteretic model does not accurately represent the inherent nonlinear behavior and resulting damage states of RC structures.This study extends the rapid building safety assessment system to low-rise RC moment resisting frame structures representing typical residential apartments in Japan.First,a safety classification for RC structures based on a damage index consistent with the current state of practice is defined.Then,a 3D nonlinear numerical model of a two-story moment frame structure is created.A simplified lumped-mass nonlinear model is developed and calibrated using the 3D model,incorporating the Takeda degradation model for the RC material nonlinearity.This model is used to simulate the seismic response and associated damage sensitive features(DSF)for random ground motion.The resulting database of responses is used to train a convolutional neural network(CNN)that performs rapid safety assessment.The developed system is validated using the 3D nonlinear analysis model subjected to historical earthquakes.The results indicate the applicability of the proposed system for RC structures following seismic events.展开更多
Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apat...Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apatite fission track dating and inverse thermal modeling,we explore the mechanism of different phases of rapid cooling for different batholiths and intrusions in the southeastern Tibetan Plateau.In contrast to previous views,we find that the coeval granitic batholith exposed in the same tectonic zone experienced differential fast uplift in different sites,indicating that the present Tibetan Plateau was the result of differential uplift rather than the entire lithosphere uplift related to lithospheric collapse during Cenozoic times.In addition,we also suggest that the 5-2 Ma mantle-related magmatism should be regarded as the critical trigger for the widely coeval cooling event in the southeastern Tibetan Plateau,because it led to the increase in atmospheric CO_(2)level and a hotter upper crust than before,which are efficient for suddenly fast rock weathering and erosion.Finally,we propose that the current landform of the southeastern Tibetan Plateau was the combined influences of tectonic and climate.展开更多
The practical application of aqueous zinc-ion batteries for large-grid scale systems is still hindered by uncontrolled zinc dendrite and side reactions.Regulating the elec-trical double layer via the electrode/electro...The practical application of aqueous zinc-ion batteries for large-grid scale systems is still hindered by uncontrolled zinc dendrite and side reactions.Regulating the elec-trical double layer via the electrode/electrolyte interface layer is an effective strategy to improve the stability of Zn anodes.Herein,we report an ultrathin zincophilic ZnS layer as a model regu-lator.At a given cycling current,the cell with Zn@ZnS electrode displays a lower potential drop over the Helmholtz layer(stern layer)and a suppressed diffuse layer,indicating the regulated charge distribution and decreased electric double layer repulsion force.Boosted zinc adsorption sites are also expected as proved by the enhanced electric double-layer capacitance.Consequently,the symmetric cell with the ZnS protection layer can stably cycle for around 3,000 h at 1 mA cm^(-2) with a lower overpotential of 25 mV.When coupled with an I2/AC cathode,the cell demonstrates a high rate performance of 160 mAh g^(-1) at 0.1 A g^(-1) and long cycling stability of over 10,000 cycles at 10 A g^(-1).The Zn||MnO_(2) also sustains both high capacity and long cycling stability of 130 mAh g^(-1) after 1,200 cycles at 0.5 A g^(-1).展开更多
Due to the mutual repulsion between their hydrophilic surface terminations and the high surface energy facilitating their ran-dom restacking,2D MXene nanosheets usually cannot self-assemble into 3D macroscopic gels wi...Due to the mutual repulsion between their hydrophilic surface terminations and the high surface energy facilitating their ran-dom restacking,2D MXene nanosheets usually cannot self-assemble into 3D macroscopic gels with various applications in the absence of proper linking agents.In this work,a rapid spontaneous gelation of Ti3C2Tx MXene with a very low dispersion concentration of 0.5 mg mL^(-1) into multifunctional architectures under moderate centrifugation is illustrated.The as-prepared MXene gels exhibit reconfigurable internal structures and tunable rheological,tribological,electrochemical,infrared-emissive and photothermal-conversion properties based on the pH-induced changes in the surface chemistry of Ti_(3)C_(2)T_(x) nanosheets.By adopting a gel with optimized pH value,high lubrication,exceptional specific capacitances(~635 and~408 F g^(-1) at 5 and 100 mV s^(-1),respectively),long-term capacitance retention(~96.7%after 10,000 cycles)and high-precision screen-or extrusion-printing into different high-resolution anticounterfeiting patterns can be achieved,thus displaying extensive potential applications in the fields of semi-solid lubrication,control-lable devices,supercapacitors,information encryption and infrared camouflaging.展开更多
A calamitous landslide happened at 22:00 on September 1,2014 in the Yunyang area of Chongqing City,southwest China,enforcing the evacuation of 508 people and damaging 23 buildings.The landslide volume comprised 1.44 m...A calamitous landslide happened at 22:00 on September 1,2014 in the Yunyang area of Chongqing City,southwest China,enforcing the evacuation of 508 people and damaging 23 buildings.The landslide volume comprised 1.44 million m^(3) of material in the source area and 0.4 million m^(3) of shoveled material.The debris flow runout extended 400 m vertically and 1600 m horizontally.The Xianchi reservoir landslide event has been investigated as follows:(1)samples collected from the main body of landslide were carried out using GCTS ring shear apparatus;(2)the parameters of shear and pore water pressure have been measured;and(3)the post-failure characteristics of landslide have been analyzed using the numerical simulation method.The excess pore-water pressure and erosion in the motion path are considered to be the key reasons for the long-runout motion and the scale-up of landslides,such as that at Xianchi,were caused by the heavy rainfall.The aim of this paper is to acquired numerical parameters and the basic resistance model,which is beneficial to improve simulation accuracy for hazard assessment for similar to potentially dangerous hillslopes in China and elsewhere.展开更多
Explosive cyclones(ECs)occur frequently over the Kuroshio/Kuroshio Extension region.The most rapidly intensified EC over the Kuroshio/Kuroshio Extension region during the 42 years(1979-2020)of cold seasons(October-Apr...Explosive cyclones(ECs)occur frequently over the Kuroshio/Kuroshio Extension region.The most rapidly intensified EC over the Kuroshio/Kuroshio Extension region during the 42 years(1979-2020)of cold seasons(October-April)was studied to reveal the variations of the key factors at different explosive-developing stages.This EC had weak low-level baroclinicity,mid-level cyclonic-vorticity advection,and strong low-level water vapor convergence at the initial explosive-developing stage.The low-level baroclinicity and mid-level cyclonic-vorticity advection increased substantially during the maximum-deepening-rate stage.The diagnostic analyses using the Zwack-Okossi equation showed that diabatic heating was the main contributor to the initial rapid intensification of this EC.The cyclonic-vorticity advection and warm-air advection enhanced rapidly in the middle and upper troposphere and contributed to the maximum rapid intensification,whereas the diabatic heating weakened slightly in the mid-low troposphere.The relative contribution of the diabatic heating decreased from the initial explosive-developing stage to the maximum-deepening-rate stage due to the enhancement of other factors(the cyclonic-vorticity advection and warm-air advection).Furthermore,the physical factors contributing to this EC varied with the explosive-developing stage.The non-key factors at the initial explosive-developing stage need attention to forecast the rapid intensification.展开更多
Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to e...Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control performance.While the nonlinear characteristic of the tire model leads to a relatively heavier computational burden.To facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)model.Then a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort requirements.The in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy consumption.Finally,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)test.The results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability.展开更多
BACKGROUND Cesarean hemorrhage is one of the serious complications,and short-term massive blood transfusion can easily cause postoperative infection and physical stress response.However,predictive nursing intervention...BACKGROUND Cesarean hemorrhage is one of the serious complications,and short-term massive blood transfusion can easily cause postoperative infection and physical stress response.However,predictive nursing intervention has important clinical significance for it.AIM To explore the effect of predictive nursing intervention on the stress response and complications of women undergoing short-term mass blood transfusion during cesarean section(CS).METHODS A clinical medical record of 100 pregnant women undergoing rapid mass blood transfusion during sections from June 2019 to June 2021.According to the different nursing methods,patients divided into control group(n=50)and observation group(n=50).Among them,the control group implemented routine nursing,and the observation group implemented predictive nursing intervention based on the control group.Moreover,compared the differences in stress res-ponse,complications,and pain scores before and after the nursing of pregnant women undergoing rapid mass blood transfusion during CS.RESULTS The anxiety and depression scores of pregnant women in the two groups were significantly improved after nursing,and the psychological stress response of the observation group was significantly lower than that of the control group(P<0.05).The heart rate and mean arterial pressure(MAP)of the observation group during delivery were lower than those of the control group,and the MAP at the end of delivery was lower than that of the control group(P<0.05).Moreover,different pain scores improved significantly in both groups,with the observation group considerably less than the control group(P<0.05).After nursing,complications such as skin rash,urinary retention,chills,diarrhea,and anaphylactic shock in the observation group were 18%,which significantly higher than in the control group(4%)(P<0.05).CONCLUSION Predictive nursing intervention can effectively relieve the pain,reduce the incidence of complications,improve mood and stress response,and serve as a reference value for the nursing of women undergoing rapid mass transfusion during CS.展开更多
Under the influence of anthropogenic and climate change,the problems caused by urban heat island(UHI)has become increasingly prominent.In order to promote urban sustainable development and improve the quality of human...Under the influence of anthropogenic and climate change,the problems caused by urban heat island(UHI)has become increasingly prominent.In order to promote urban sustainable development and improve the quality of human settlements,it is significant for exploring the evolution characteristics of urban thermal environment and analyzing its driving forces.Taking the Landsat series images as the basic data sources,the winter land surface temperature(LST)of the rapid urbanization area of Fuzhou City in China was quantitatively retrieved from 2001 to 2021.Combing comprehensively the standard deviation ellipse model,profile analysis and GeoDetector model,the spatio-temporal evolution characteristics and influencing factors of the winter urban thermal environment were systematically analyzed.The results showed that the winter LST presented an increasing trend in the study area during 2001–2021,and the winter LST of the central urban regions was significantly higher than the suburbs.There was a strong UHI effect from 2001 to 2021with an expansion trend from the central urban regions to the suburbs and coastal areas in space scale.The LST of green lands and wetlands are significantly lower than croplands,artificial surface and unvegetated lands.Vegetation and water bodies had a significant mitigation effect on UHI,especially in the micro-scale.The winter UHI had been jointly driven by the underlying surface and socio-economic factors in a nonlinear or two-factor interactive enhancement mode,and socio-economic factors had played a leading role.This research could provide data support and decision-making references for rationally planning urban layout and promoting sustainable urban development.展开更多
BACKGROUND Restrictive practices(RPs)are defined by measures linked to physical and chemical restraints to reduce the movement or control behaviours during any emergency.Seclusion is an equal part of RPs intended to i...BACKGROUND Restrictive practices(RPs)are defined by measures linked to physical and chemical restraints to reduce the movement or control behaviours during any emergency.Seclusion is an equal part of RPs intended to isolate and reduce the sensory stimulation to safeguard the patient and those within the vicinity.Using interventions by way of virtual reality(VR)could assist with reducing the need for RPs as it could help reduce anxiety or agitation by way of placing users into realistic and immersive environments.This could also aid staff to and change current RPs.AIM To assess the feasibility and effectiveness of using a VR platform to provide reduction in RP training.METHODS A randomised controlled feasibility study,accompanied by evaluations at 1 month and 6 months,was conducted within inpatient psychiatric wards at Southern Health National Health Service Foundation Trust,United Kingdom.Virti VR scenarios were used on VR headsets to provide training on reducing RPs in 3 inpatient psychiatric wards.Outcome measures included general self-efficacy scale,generalised anxiety disorder assessment 7(GAD-7),Burnout Assessment Tool 12,the Everyday Discrimination Scale,and the Compassionate Engagement and Action Scale.RESULTS Findings revealed statistically significant differences between the VR and treatment as usual groups,in the Everyday Discrimination Scale items Q8 and Q9:P=0.023 and P=0.040 respectively,indicating higher levels of perceived discrimination in the VR group.There were no significant differences between groups in terms of general self-efficacy,generalised anxiety disorder assessment 9,and Burnout Assessment Tool 12 scores.A significant difference was observed within the VR group for compassionate engagement from others(P=0.005)over time.Most respondents recorded System Usability Scale scores above 70,with an average score of 71.79.There was a significant reduction in rates of RPs in the VR group vs treatment as usual group with a fluctuating variability observed in the VR group likely due to external factors not captured in the study.CONCLUSION Ongoing advancement of VR technology enables the possibility of creating scenarios and simulations tailored to healthcare environments that empower staff by providing more comprehensive and effective training for handling situations.展开更多
大脑中动脉M2段(M2 segment of middle cerebral artery, MCA-M2)是颈内动脉系统的重要分支,大脑中动脉M2段闭塞脑梗死导致的神经功能缺损对患者家庭及社会带来了沉重的负担。大脑中动脉M2段闭塞脑梗死的介入治疗目前仍存在争议。目前...大脑中动脉M2段(M2 segment of middle cerebral artery, MCA-M2)是颈内动脉系统的重要分支,大脑中动脉M2段闭塞脑梗死导致的神经功能缺损对患者家庭及社会带来了沉重的负担。大脑中动脉M2段闭塞脑梗死的介入治疗目前仍存在争议。目前有研究表明大脑中动脉M2段闭塞脑梗死血管内治疗优于传统的内科治疗。RAPID软件在急性缺血性脑卒中患者行血管内治疗的决策中提供帮助得到认可,但对于大脑中动脉M2段闭塞脑梗死的血管内治疗适应症的选择缺乏定论。本文就大脑中动脉M2段闭塞脑梗死血管内治疗疗效及Rapid软件筛选合适大脑中动脉M2段闭塞脑梗死介入治疗患者做一综述。The M2 segment of middle cerebral artery (MCA-M2) is an important branch of the internal carotid artery system. Cerebral infarction caused by M2 segment occlusion of MCA-M2 has brought a heavy burden on the family and society. The interventional treatment of M2 segment occlusion of MCA-M2 is still controversial. Current studies have shown that endovascular treatment of M2 segment occlusion of MCA-M2 is superior to traditional medical treatment. RAPID software has been recognized as a helpful tool in the decision-making of endovascular treatment for patients with acute ischemic stroke, but there is a lack of a definite conclusion on the indications for endovascular treatment of M2 segment occlusion of MCA-M2. This article reviews the efficacy of endovascular treatment of M2 segment occlusion of MCA-M2 and the selection of suitable patients for interventional treatment of M2 segment occlusion of MCA-M2 with Rapid software.展开更多
The application of pesticides (mostly insecticides and fungicides) during the tea-planting process will undoubtedly increase the dietary risk associated with drinking tea. Thus, it is necessary to ascertain whether pe...The application of pesticides (mostly insecticides and fungicides) during the tea-planting process will undoubtedly increase the dietary risk associated with drinking tea. Thus, it is necessary to ascertain whether pesticide residues in tea products exceed the maximum residue limits. However, the complex matrices present in tea samples comprise a major challenge in the analytical detection of pesticide residues. In this study, nine types of lateral flow immunochromatographic strips (LFICSs) were developed to detect the pesticides of interest (fenpropathrin, chlorpyrifos, imidacloprid, thiamethoxam, acetamiprid, carbendazim, chlorothalonil, pyraclostrobin, and iprodione). To reduce the interference of tea substrates on the assay sensitivity, the pretreatment conditions for tea samples, including the extraction solvent, extraction time, and purification agent, were optimized for the simultaneous detection of these pesticides. The entire testing procedure (including pretreatment and detection) could be completed within 30 min. The detected results of authentic tea samples were confirmed by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), which suggest that the LFICS coupled with sample rapid pretreatment can be used for on-site rapid screening of the target pesticide in tea products prior to their market release.展开更多
In real-time operations,the minutely/hourly updated high-resolution rapid refresh(HRRR)system is one of the most expensive numerical weather prediction(NWP)models.Based on a twenty-member HRRR-time-lagged-ensemble(HRR...In real-time operations,the minutely/hourly updated high-resolution rapid refresh(HRRR)system is one of the most expensive numerical weather prediction(NWP)models.Based on a twenty-member HRRR-time-lagged-ensemble(HRRR-TLE)system developed from two real-time convection-permitting HRRR models,CMA-GD(R3)and CMA-SH3,from the China Meteorological Administration(CMA),this study proposes an optimized probability-matching(OPM)technique to improve 0−12 h quantitative precipitation forecasts(QPFs)based on the correlation and error relationships between ensemble forecasts and observations during the training window.Then,a series of sensitivity experiments using different cost functions and optimized ratios was conducted to further improve OPM predictions.The results indicate that:(1)In the HRRR-TLE system,there is no always optimal member in both weak rain and severe rain forecasts,as measured by the equitable threat score(ETS)and bias extent(BE)at four thresholds(1+,5+,10+,and 20+mm h^(-1);e.g.,“1+”means≥1).(2)Compared with the HRRR-TLE system,the QPFs generated by the traditional PM technique showed a notable increase in ETS and a decrease in BE at all of the above thresholds.Compared with the traditional probability-matching method(PM),OPM can generate more skillful forecasts on both spatial representations and rain rates by using the sliding-weight method and optimized ensembles,respectively.(3)In particular,in the 20+mm h^(-1)forecasts,which are often difficult to predict,the ETS of the optimal OPM test,with a 20%optimization ratio and symmetric mean absolute percentage error cost function,increased by 64.6%,and the BE decreased by 5.7%,relative to PM.Moreover,OPM shows good stability in both daytime and nighttime periods.展开更多
The Mg-Y-Zn magnesium alloy system is commonly recognized for its remarkable combination of high strength and ductility,achieved even with minimal amounts of alloying elements.This exceptional performance is attribute...The Mg-Y-Zn magnesium alloy system is commonly recognized for its remarkable combination of high strength and ductility,achieved even with minimal amounts of alloying elements.This exceptional performance is attributed to its unique microstructure,which includes Long-Period Stacking Ordered(LPSO)phases or the distinctive microstructure derived from the LPSO phase,referred to as the Mille-Feuille structure(MFS).This study systematically compares the traditional ingot metallurgy method with the rapid solidification technique,coupled with diverse heat treatments and extrusion processes.Microscopic analyses reveal variations in the presence of LPSO phases,Mille-Feuille structure,and grain size,leading to divergent mechanical and corrosion properties.The rapid solidification approach stands out,ensuring superior mechanical properties alongside a reasonable corrosion rate.展开更多
The dynamic surface self-reconstruction behavior in local structure correlates with oxygen evolution reaction(OER)performance,which has become an effective strategy for constructing the catalytic active phase.However,...The dynamic surface self-reconstruction behavior in local structure correlates with oxygen evolution reaction(OER)performance,which has become an effective strategy for constructing the catalytic active phase.However,it remains a challenge to understand the mechanisms of reconstruction and to accomplish it fast and deeply.Here,we reported a photo-promoted rapid reconstruction(PRR)process on Ag nanoparticle-loaded amorphous Ni-Fe hydroxide nanosheets on carbon cloth for enhanced OER.The photogenerated holes generated by Ag in conjunction with the anodic potential contributed to a thorough reconstruction of the amorphous substrate.The valence state of unsaturated coordinated Fe atoms,which serve as active sites,is significantly increased,while the corresponding crystalline substrate shows little change.The different structural evolutions of amorphous and crystalline substrates during reconstruction lead to diverse pathways of OER.This PRR utilizing loaded noble metal nanoparticles can accelerate the generation of active species in the substrate and increase the electrical conductivity,which provides a new inspiration to develop efficient catalysts via reconstruction strategies.展开更多
Background Broilers stand out as one of the fastest-growing livestock globally,making a substantial contribution to animal meat production.However,the molecular and epigenetic mechanisms underlying the rapid growth an...Background Broilers stand out as one of the fastest-growing livestock globally,making a substantial contribution to animal meat production.However,the molecular and epigenetic mechanisms underlying the rapid growth and development of broiler chickens are still unclear.This study aims to explore muscle development patterns and regulatory networks during the postnatal rapid growth phase of fast-growing broilers.We measured the growth performance of Cornish(CC)and White Plymouth Rock(RR)over a 42-d period.Pectoral muscle samples from both CC and RR were randomly collected at day 21 after hatching(D21)and D42 for RNA-seq and ATAC-seq library construction.Results The consistent increase in body weight and pectoral muscle weight across both breeds was observed as they matured,with CC outpacing RR in terms of weight at each stage of development.Differential expression analysis identified 398 and 1,129 genes in the two dimensions of breeds and ages,respectively.A total of 75,149 ATAC-seq peaks were annotated in promoter,exon,intron and intergenic regions,with a higher number of peaks in the promoter and intronic regions.The age-biased genes and breed-biased genes of RNA-seq were combined with the ATAC-seq data for subsequent analysis.The results spotlighted the upregulation of ACTC1 and FDPS at D21,which were primarily associated with muscle structure development by gene cluster enrichment.Additionally,a noteworthy upregulation of MUSTN1,FOS and TGFB3 was spotted in broiler chickens at D42,which were involved in cell differentiation and muscle regeneration after injury,suggesting a regulatory role of muscle growth and repair.Conclusions This work provided a regulatory network of postnatal broiler chickens and revealed ACTC1 and MUSTN1 as the key responsible for muscle development and regeneration.Our findings highlight that rapid growth in broiler chickens triggers ongoing muscle damage and subsequent regeneration.These findings provide a foundation for future research to investigate the functional aspects of muscle development.展开更多
Trees progress through various growth stages,each marked by specific responses and adaptation strate-gies to environmental conditions.Despite the importance of age-related growth responses on overall forest health and...Trees progress through various growth stages,each marked by specific responses and adaptation strate-gies to environmental conditions.Despite the importance of age-related growth responses on overall forest health and management policies,limited knowledge exists regarding age-related effects on dendroclimatic relationships in key subtropical tree species.In this study,we employed a den-drochronological method to examine the impact of rapid warming on growth dynamics and climatic sensitivity of young(40–60 years)and old(100–180 years)Pinus mas-soniana forests across six sites in central-southern China.The normalized log basal area increment of trees in both age groups increased significantly following rapid warming in 1984.Trees in young forests further showed a distinct growth decline during a prolonged severe drought(2004–2013),whereas those in old forests maintained growth increases.Tree growth was more strongly influenced by temperature than by moisture,particularly in old forests.Spring tem-peratures strongly and positively impacted the growth of old trees but had a weaker effect on young ones.Old forests had a significantly lower resistance to extreme drought but faster recovery compared to young forests.The“divergence problem”was more pronounced in younger forests due to their heightened sensitivity to warming-induced drought and heat stress.With ongoing warming,young forests also may initially experience a growth decline due to their heightened sensitivity to winter drought.Our findings underscore the importance of considering age-dependent changes in forest/tree growth response to warming in subtropical forest man-agement,particularly in the context of achieving“Carbon Peak&Carbon Neutrality”goals in China.展开更多
Magnesium alloys are emerging as promising alternatives to traditional orthopedic implant materials thanks to their biodegradability,biocompatibility,and impressive mechanical characteristics.However,their rapid in-vi...Magnesium alloys are emerging as promising alternatives to traditional orthopedic implant materials thanks to their biodegradability,biocompatibility,and impressive mechanical characteristics.However,their rapid in-vivo degradation presents challenges,notably in upholding mechanical integrity over time.This study investigates the impact of high-temperature thermal processing on the mechanical and degradation attributes of a lean Mg-Zn-Ca-Mn alloy,ZX10.Utilizing rapid,cost-efficient characterization methods like X-ray diffraction and optical microscopy,we swiftly examine microstructural changes post-thermal treatment.Employing Pearson correlation coefficient analysis,we unveil the relationship between microstructural properties and critical targets(properties):hardness and corrosion resistance.Additionally,leveraging the least absolute shrinkage and selection operator(LASSO),we pinpoint the dominant microstructural factors among closely correlated variables.Our findings underscore the significant role of grain size refinement in strengthening and the predominance of the ternary Ca_(2)Mg_(6)Zn_(3)phase in corrosion behavior.This suggests that achieving an optimal blend of strength and corrosion resistance is attainable through fine grains and reduced concentration of ternary phases.This thorough investigation furnishes valuable insights into the intricate interplay of processing,structure,and properties in magnesium alloys,thereby advancing the development of superior biodegradable implant materials.展开更多
文摘CARE FOR THE ELDERLY Sanlian Lifeweek 25 November 2024 China is coping with a rapidly aging population.O!cial data shows that the number of people aged 60 and older was almost 297 million in 2023,comprising 21.1 percent of the total population.This proportion is expected to exceed 30 percent by 2035.
基金supported by a fellowship from Design Department of Taisei Corporation。
文摘Many countries throughout the world have experienced large earthquakes,which cause building damage or collapse.After such earthquakes,structures must be inspected rapidly to judge whether they are safe to reoccupy.To facilitate the inspection process,the authors previously developed a rapid building safety assessment system using sparse acceleration measurements for steel framed buildings.The proposed system modeled nonlinearity in the measurement data using a calibrated simplified lumped-mass model and convolutional neural networks(CNNs),based on which the buildinglevel damage index was estimated rapidly after earthquakes.The proposed system was validated for a nonlinear 3D numerical model of a five-story steel building,and later for a large-scale specimen of an 18-story building in Japan tested on the E-Defense shaking table.However,the applicability of the safety assessment system for reinforced concrete(RC)structures with complex hysteretic material nonlinearity has yet to be explored;the previous approach based on a simplified lumpedmass model with a Bouc-Wen hysteretic model does not accurately represent the inherent nonlinear behavior and resulting damage states of RC structures.This study extends the rapid building safety assessment system to low-rise RC moment resisting frame structures representing typical residential apartments in Japan.First,a safety classification for RC structures based on a damage index consistent with the current state of practice is defined.Then,a 3D nonlinear numerical model of a two-story moment frame structure is created.A simplified lumped-mass nonlinear model is developed and calibrated using the 3D model,incorporating the Takeda degradation model for the RC material nonlinearity.This model is used to simulate the seismic response and associated damage sensitive features(DSF)for random ground motion.The resulting database of responses is used to train a convolutional neural network(CNN)that performs rapid safety assessment.The developed system is validated using the 3D nonlinear analysis model subjected to historical earthquakes.The results indicate the applicability of the proposed system for RC structures following seismic events.
基金supported by National Natural Science Foundation of China(Grant Nos.42025301,41730213 and 41890831)the Second Tibetan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0702)+2 种基金Hong Kong RGC GRF(Grant No.17307918)HKU Internal Grants for Member of Chinese Academy of Sciences(Grant No.102009906)for Distinguished Research Achievement Award(Grant No.102010100)。
文摘Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apatite fission track dating and inverse thermal modeling,we explore the mechanism of different phases of rapid cooling for different batholiths and intrusions in the southeastern Tibetan Plateau.In contrast to previous views,we find that the coeval granitic batholith exposed in the same tectonic zone experienced differential fast uplift in different sites,indicating that the present Tibetan Plateau was the result of differential uplift rather than the entire lithosphere uplift related to lithospheric collapse during Cenozoic times.In addition,we also suggest that the 5-2 Ma mantle-related magmatism should be regarded as the critical trigger for the widely coeval cooling event in the southeastern Tibetan Plateau,because it led to the increase in atmospheric CO_(2)level and a hotter upper crust than before,which are efficient for suddenly fast rock weathering and erosion.Finally,we propose that the current landform of the southeastern Tibetan Plateau was the combined influences of tectonic and climate.
基金financially supported by the Natural Sciences and Engineering Research Council of Canada (NSERC),through the Discovery Grant Program (RGPIN-2018-06725)the Discovery Accelerator Supplement Grant program (RGPAS-2018-522651)+2 种基金the New Frontiers in Research Fund-Exploration program (NFRFE-2019-00488)supported by funding from the Canada First Research Excellence Fund as part of the University of Alberta’s Future Energy Systems research initiative (FES-T06-Q03)supported by the Chinese Scholarship Council (CSC)(Grant No. 202006450027).
文摘The practical application of aqueous zinc-ion batteries for large-grid scale systems is still hindered by uncontrolled zinc dendrite and side reactions.Regulating the elec-trical double layer via the electrode/electrolyte interface layer is an effective strategy to improve the stability of Zn anodes.Herein,we report an ultrathin zincophilic ZnS layer as a model regu-lator.At a given cycling current,the cell with Zn@ZnS electrode displays a lower potential drop over the Helmholtz layer(stern layer)and a suppressed diffuse layer,indicating the regulated charge distribution and decreased electric double layer repulsion force.Boosted zinc adsorption sites are also expected as proved by the enhanced electric double-layer capacitance.Consequently,the symmetric cell with the ZnS protection layer can stably cycle for around 3,000 h at 1 mA cm^(-2) with a lower overpotential of 25 mV.When coupled with an I2/AC cathode,the cell demonstrates a high rate performance of 160 mAh g^(-1) at 0.1 A g^(-1) and long cycling stability of over 10,000 cycles at 10 A g^(-1).The Zn||MnO_(2) also sustains both high capacity and long cycling stability of 130 mAh g^(-1) after 1,200 cycles at 0.5 A g^(-1).
基金This work is financially supported by the Hundred Talents Program of Chinese Academy of Sciences(E30247YB)the Special Talents Program of Lanzhou Institute of Chemical Physics(E0SX0282)+1 种基金the National Natural Science Foundation of Shandong Province(ZR2022QB190)the Innovative Research Funds of Shandong Laboratory of Advanced Materials and Green Manufacturing at Yantai(E1R06SXM07,E1R06SXM09 and E2R06SXM14).
文摘Due to the mutual repulsion between their hydrophilic surface terminations and the high surface energy facilitating their ran-dom restacking,2D MXene nanosheets usually cannot self-assemble into 3D macroscopic gels with various applications in the absence of proper linking agents.In this work,a rapid spontaneous gelation of Ti3C2Tx MXene with a very low dispersion concentration of 0.5 mg mL^(-1) into multifunctional architectures under moderate centrifugation is illustrated.The as-prepared MXene gels exhibit reconfigurable internal structures and tunable rheological,tribological,electrochemical,infrared-emissive and photothermal-conversion properties based on the pH-induced changes in the surface chemistry of Ti_(3)C_(2)T_(x) nanosheets.By adopting a gel with optimized pH value,high lubrication,exceptional specific capacitances(~635 and~408 F g^(-1) at 5 and 100 mV s^(-1),respectively),long-term capacitance retention(~96.7%after 10,000 cycles)and high-precision screen-or extrusion-printing into different high-resolution anticounterfeiting patterns can be achieved,thus displaying extensive potential applications in the fields of semi-solid lubrication,control-lable devices,supercapacitors,information encryption and infrared camouflaging.
基金supported by the China Geological Survey Project(Grant No.DD20211314)the Fundamental Research Funds for Chinese Academy of Geological Science(No.JKY202122).
文摘A calamitous landslide happened at 22:00 on September 1,2014 in the Yunyang area of Chongqing City,southwest China,enforcing the evacuation of 508 people and damaging 23 buildings.The landslide volume comprised 1.44 million m^(3) of material in the source area and 0.4 million m^(3) of shoveled material.The debris flow runout extended 400 m vertically and 1600 m horizontally.The Xianchi reservoir landslide event has been investigated as follows:(1)samples collected from the main body of landslide were carried out using GCTS ring shear apparatus;(2)the parameters of shear and pore water pressure have been measured;and(3)the post-failure characteristics of landslide have been analyzed using the numerical simulation method.The excess pore-water pressure and erosion in the motion path are considered to be the key reasons for the long-runout motion and the scale-up of landslides,such as that at Xianchi,were caused by the heavy rainfall.The aim of this paper is to acquired numerical parameters and the basic resistance model,which is beneficial to improve simulation accuracy for hazard assessment for similar to potentially dangerous hillslopes in China and elsewhere.
基金jointly funded by the State Key Program of the National Natural Science Foundation of China(No.42130605)the Major Program of the National Natural Science Foundation of China(No.72293604)+5 种基金the Youth Innovative Talents Program of Guangdong Colleges and Universities(No.2022KQNCX026)the Natural Science Foundation of Shandong(No.ZR2022MD038)the Project of Enhancing School with Innovation of Guangdong Ocean University(No.230419106)the State Key Program of the National Natural Science Foundation of China(No.42130605)the National Natural Science Foundation of China(Nos.42275001,42276019,42205014,and 42275017)the Guangdong Ocean University Ph.D.Scientific Research Program(No.R19045).
文摘Explosive cyclones(ECs)occur frequently over the Kuroshio/Kuroshio Extension region.The most rapidly intensified EC over the Kuroshio/Kuroshio Extension region during the 42 years(1979-2020)of cold seasons(October-April)was studied to reveal the variations of the key factors at different explosive-developing stages.This EC had weak low-level baroclinicity,mid-level cyclonic-vorticity advection,and strong low-level water vapor convergence at the initial explosive-developing stage.The low-level baroclinicity and mid-level cyclonic-vorticity advection increased substantially during the maximum-deepening-rate stage.The diagnostic analyses using the Zwack-Okossi equation showed that diabatic heating was the main contributor to the initial rapid intensification of this EC.The cyclonic-vorticity advection and warm-air advection enhanced rapidly in the middle and upper troposphere and contributed to the maximum rapid intensification,whereas the diabatic heating weakened slightly in the mid-low troposphere.The relative contribution of the diabatic heating decreased from the initial explosive-developing stage to the maximum-deepening-rate stage due to the enhancement of other factors(the cyclonic-vorticity advection and warm-air advection).Furthermore,the physical factors contributing to this EC varied with the explosive-developing stage.The non-key factors at the initial explosive-developing stage need attention to forecast the rapid intensification.
基金Supported by National Natural Science Foundation of China(Grant Nos.51975118,52025121)Foundation of State Key Laboratory of Automotive Simulation and Control of China(Grant No.20210104)+1 种基金Foundation of State Key Laboratory of Automobile Safety and Energy Saving of China(Grant No.KFZ2201)Special Fund of Jiangsu Province for the Transformation of Scientific and Technological Achievements of China(Grant No.BA2021023).
文摘Four-wheel independently driven electric vehicles(FWID-EV)endow a flexible and scalable control framework to improve vehicle performance.This paper integrates the torque vectoring and active suspension system(ASS)to enhance the vehicle’s longitudinal and vertical motion control performance.While the nonlinear characteristic of the tire model leads to a relatively heavier computational burden.To facilitate the controller design and ease the load,a half-vehicle dynamics system is built and simplified to the linear-time-varying(LTV)model.Then a model predictive controller is developed by formulating the objective function by comprehensively considering the safety,energy-saving and comfort requirements.The in-wheel motor efficiency and the power loss of tire slip are treated as optimization indices in this work to reduce energy consumption.Finally,the effectiveness of the proposed controller is verified through the rapid-control-prototype(RCP)test.The results demonstrate the enhancement of the energy-saving as well as comfort on the basis of vehicle stability.
文摘BACKGROUND Cesarean hemorrhage is one of the serious complications,and short-term massive blood transfusion can easily cause postoperative infection and physical stress response.However,predictive nursing intervention has important clinical significance for it.AIM To explore the effect of predictive nursing intervention on the stress response and complications of women undergoing short-term mass blood transfusion during cesarean section(CS).METHODS A clinical medical record of 100 pregnant women undergoing rapid mass blood transfusion during sections from June 2019 to June 2021.According to the different nursing methods,patients divided into control group(n=50)and observation group(n=50).Among them,the control group implemented routine nursing,and the observation group implemented predictive nursing intervention based on the control group.Moreover,compared the differences in stress res-ponse,complications,and pain scores before and after the nursing of pregnant women undergoing rapid mass blood transfusion during CS.RESULTS The anxiety and depression scores of pregnant women in the two groups were significantly improved after nursing,and the psychological stress response of the observation group was significantly lower than that of the control group(P<0.05).The heart rate and mean arterial pressure(MAP)of the observation group during delivery were lower than those of the control group,and the MAP at the end of delivery was lower than that of the control group(P<0.05).Moreover,different pain scores improved significantly in both groups,with the observation group considerably less than the control group(P<0.05).After nursing,complications such as skin rash,urinary retention,chills,diarrhea,and anaphylactic shock in the observation group were 18%,which significantly higher than in the control group(4%)(P<0.05).CONCLUSION Predictive nursing intervention can effectively relieve the pain,reduce the incidence of complications,improve mood and stress response,and serve as a reference value for the nursing of women undergoing rapid mass transfusion during CS.
基金Under the auspices of the Social Science and Humanity on Young Fund of the Ministry of Education of China(No.21YJCZH100)the Scientific Research Project on Outstanding Young of the Fujian Agriculture and Forestry University(No.XJQ201920)+1 种基金the Science and Technology Innovation Special Fund Project of Fujian Agriculture and Forestry University(No.CXZX2021032)the Forestry Peak Discipline Construction Project of Fujian Agriculture and Forestry University(No.72202200205)。
文摘Under the influence of anthropogenic and climate change,the problems caused by urban heat island(UHI)has become increasingly prominent.In order to promote urban sustainable development and improve the quality of human settlements,it is significant for exploring the evolution characteristics of urban thermal environment and analyzing its driving forces.Taking the Landsat series images as the basic data sources,the winter land surface temperature(LST)of the rapid urbanization area of Fuzhou City in China was quantitatively retrieved from 2001 to 2021.Combing comprehensively the standard deviation ellipse model,profile analysis and GeoDetector model,the spatio-temporal evolution characteristics and influencing factors of the winter urban thermal environment were systematically analyzed.The results showed that the winter LST presented an increasing trend in the study area during 2001–2021,and the winter LST of the central urban regions was significantly higher than the suburbs.There was a strong UHI effect from 2001 to 2021with an expansion trend from the central urban regions to the suburbs and coastal areas in space scale.The LST of green lands and wetlands are significantly lower than croplands,artificial surface and unvegetated lands.Vegetation and water bodies had a significant mitigation effect on UHI,especially in the micro-scale.The winter UHI had been jointly driven by the underlying surface and socio-economic factors in a nonlinear or two-factor interactive enhancement mode,and socio-economic factors had played a leading role.This research could provide data support and decision-making references for rationally planning urban layout and promoting sustainable urban development.
文摘BACKGROUND Restrictive practices(RPs)are defined by measures linked to physical and chemical restraints to reduce the movement or control behaviours during any emergency.Seclusion is an equal part of RPs intended to isolate and reduce the sensory stimulation to safeguard the patient and those within the vicinity.Using interventions by way of virtual reality(VR)could assist with reducing the need for RPs as it could help reduce anxiety or agitation by way of placing users into realistic and immersive environments.This could also aid staff to and change current RPs.AIM To assess the feasibility and effectiveness of using a VR platform to provide reduction in RP training.METHODS A randomised controlled feasibility study,accompanied by evaluations at 1 month and 6 months,was conducted within inpatient psychiatric wards at Southern Health National Health Service Foundation Trust,United Kingdom.Virti VR scenarios were used on VR headsets to provide training on reducing RPs in 3 inpatient psychiatric wards.Outcome measures included general self-efficacy scale,generalised anxiety disorder assessment 7(GAD-7),Burnout Assessment Tool 12,the Everyday Discrimination Scale,and the Compassionate Engagement and Action Scale.RESULTS Findings revealed statistically significant differences between the VR and treatment as usual groups,in the Everyday Discrimination Scale items Q8 and Q9:P=0.023 and P=0.040 respectively,indicating higher levels of perceived discrimination in the VR group.There were no significant differences between groups in terms of general self-efficacy,generalised anxiety disorder assessment 9,and Burnout Assessment Tool 12 scores.A significant difference was observed within the VR group for compassionate engagement from others(P=0.005)over time.Most respondents recorded System Usability Scale scores above 70,with an average score of 71.79.There was a significant reduction in rates of RPs in the VR group vs treatment as usual group with a fluctuating variability observed in the VR group likely due to external factors not captured in the study.CONCLUSION Ongoing advancement of VR technology enables the possibility of creating scenarios and simulations tailored to healthcare environments that empower staff by providing more comprehensive and effective training for handling situations.
文摘大脑中动脉M2段(M2 segment of middle cerebral artery, MCA-M2)是颈内动脉系统的重要分支,大脑中动脉M2段闭塞脑梗死导致的神经功能缺损对患者家庭及社会带来了沉重的负担。大脑中动脉M2段闭塞脑梗死的介入治疗目前仍存在争议。目前有研究表明大脑中动脉M2段闭塞脑梗死血管内治疗优于传统的内科治疗。RAPID软件在急性缺血性脑卒中患者行血管内治疗的决策中提供帮助得到认可,但对于大脑中动脉M2段闭塞脑梗死的血管内治疗适应症的选择缺乏定论。本文就大脑中动脉M2段闭塞脑梗死血管内治疗疗效及Rapid软件筛选合适大脑中动脉M2段闭塞脑梗死介入治疗患者做一综述。The M2 segment of middle cerebral artery (MCA-M2) is an important branch of the internal carotid artery system. Cerebral infarction caused by M2 segment occlusion of MCA-M2 has brought a heavy burden on the family and society. The interventional treatment of M2 segment occlusion of MCA-M2 is still controversial. Current studies have shown that endovascular treatment of M2 segment occlusion of MCA-M2 is superior to traditional medical treatment. RAPID software has been recognized as a helpful tool in the decision-making of endovascular treatment for patients with acute ischemic stroke, but there is a lack of a definite conclusion on the indications for endovascular treatment of M2 segment occlusion of MCA-M2. This article reviews the efficacy of endovascular treatment of M2 segment occlusion of MCA-M2 and the selection of suitable patients for interventional treatment of M2 segment occlusion of MCA-M2 with Rapid software.
基金supported by grants from Shanghai Agriculture Applied Technology Development Program,China(Grant No.:2020-02-08-00-08-F01456)the Key Research and Development Program of Zhejiang Province,China(Grant No.:2020C02024-2).
文摘The application of pesticides (mostly insecticides and fungicides) during the tea-planting process will undoubtedly increase the dietary risk associated with drinking tea. Thus, it is necessary to ascertain whether pesticide residues in tea products exceed the maximum residue limits. However, the complex matrices present in tea samples comprise a major challenge in the analytical detection of pesticide residues. In this study, nine types of lateral flow immunochromatographic strips (LFICSs) were developed to detect the pesticides of interest (fenpropathrin, chlorpyrifos, imidacloprid, thiamethoxam, acetamiprid, carbendazim, chlorothalonil, pyraclostrobin, and iprodione). To reduce the interference of tea substrates on the assay sensitivity, the pretreatment conditions for tea samples, including the extraction solvent, extraction time, and purification agent, were optimized for the simultaneous detection of these pesticides. The entire testing procedure (including pretreatment and detection) could be completed within 30 min. The detected results of authentic tea samples were confirmed by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS), which suggest that the LFICS coupled with sample rapid pretreatment can be used for on-site rapid screening of the target pesticide in tea products prior to their market release.
基金Natural Science Foundation of Hunan Province(2021JC0009)National Natural Science Foundation of China(42375002,42105146)Key Projects of Hunan Meteorological Bureau(XQKJ22A004)。
文摘In real-time operations,the minutely/hourly updated high-resolution rapid refresh(HRRR)system is one of the most expensive numerical weather prediction(NWP)models.Based on a twenty-member HRRR-time-lagged-ensemble(HRRR-TLE)system developed from two real-time convection-permitting HRRR models,CMA-GD(R3)and CMA-SH3,from the China Meteorological Administration(CMA),this study proposes an optimized probability-matching(OPM)technique to improve 0−12 h quantitative precipitation forecasts(QPFs)based on the correlation and error relationships between ensemble forecasts and observations during the training window.Then,a series of sensitivity experiments using different cost functions and optimized ratios was conducted to further improve OPM predictions.The results indicate that:(1)In the HRRR-TLE system,there is no always optimal member in both weak rain and severe rain forecasts,as measured by the equitable threat score(ETS)and bias extent(BE)at four thresholds(1+,5+,10+,and 20+mm h^(-1);e.g.,“1+”means≥1).(2)Compared with the HRRR-TLE system,the QPFs generated by the traditional PM technique showed a notable increase in ETS and a decrease in BE at all of the above thresholds.Compared with the traditional probability-matching method(PM),OPM can generate more skillful forecasts on both spatial representations and rain rates by using the sliding-weight method and optimized ensembles,respectively.(3)In particular,in the 20+mm h^(-1)forecasts,which are often difficult to predict,the ETS of the optimal OPM test,with a 20%optimization ratio and symmetric mean absolute percentage error cost function,increased by 64.6%,and the BE decreased by 5.7%,relative to PM.Moreover,OPM shows good stability in both daytime and nighttime periods.
基金supported by Japan Society for the Promotion of Science(KAKENHI Grant-in-Aid for Scientific Research18H05475,18H05476 and JP20H00312)+2 种基金MRC International Collaborative Research Grant.The authors would like to thank the Czech Science Foundation(Project No.22-22248S)specific university research(A1_FCHT_2024_007)for financial supportthe assistance provided by the Ferroic Multifunctionalities project,supported by the Ministry of Education,Youth,and Sports of the Czech Republic.Project No.CZ.02.01.01/00/22_008/0004591,co-funded by the European Union.CzechNanoLab project LM2023051 funded by MEYS CR is gratefully acknowledged for the financial support of the measurements/sample fabrication at LNSM Research Infrastructure.
文摘The Mg-Y-Zn magnesium alloy system is commonly recognized for its remarkable combination of high strength and ductility,achieved even with minimal amounts of alloying elements.This exceptional performance is attributed to its unique microstructure,which includes Long-Period Stacking Ordered(LPSO)phases or the distinctive microstructure derived from the LPSO phase,referred to as the Mille-Feuille structure(MFS).This study systematically compares the traditional ingot metallurgy method with the rapid solidification technique,coupled with diverse heat treatments and extrusion processes.Microscopic analyses reveal variations in the presence of LPSO phases,Mille-Feuille structure,and grain size,leading to divergent mechanical and corrosion properties.The rapid solidification approach stands out,ensuring superior mechanical properties alongside a reasonable corrosion rate.
基金This work was supported by the National Natural Science Foundation of China(52073008,52272181)the China Postdoctoral Science Foundation(2023T160036).
文摘The dynamic surface self-reconstruction behavior in local structure correlates with oxygen evolution reaction(OER)performance,which has become an effective strategy for constructing the catalytic active phase.However,it remains a challenge to understand the mechanisms of reconstruction and to accomplish it fast and deeply.Here,we reported a photo-promoted rapid reconstruction(PRR)process on Ag nanoparticle-loaded amorphous Ni-Fe hydroxide nanosheets on carbon cloth for enhanced OER.The photogenerated holes generated by Ag in conjunction with the anodic potential contributed to a thorough reconstruction of the amorphous substrate.The valence state of unsaturated coordinated Fe atoms,which serve as active sites,is significantly increased,while the corresponding crystalline substrate shows little change.The different structural evolutions of amorphous and crystalline substrates during reconstruction lead to diverse pathways of OER.This PRR utilizing loaded noble metal nanoparticles can accelerate the generation of active species in the substrate and increase the electrical conductivity,which provides a new inspiration to develop efficient catalysts via reconstruction strategies.
基金supported by the National Key Research and Development Program of China(2022YFF1000204)the National Natural Science Foundation of China(32102535)the Key Research and Development Program of Hainan province(ZDYF2023XDNY036)。
文摘Background Broilers stand out as one of the fastest-growing livestock globally,making a substantial contribution to animal meat production.However,the molecular and epigenetic mechanisms underlying the rapid growth and development of broiler chickens are still unclear.This study aims to explore muscle development patterns and regulatory networks during the postnatal rapid growth phase of fast-growing broilers.We measured the growth performance of Cornish(CC)and White Plymouth Rock(RR)over a 42-d period.Pectoral muscle samples from both CC and RR were randomly collected at day 21 after hatching(D21)and D42 for RNA-seq and ATAC-seq library construction.Results The consistent increase in body weight and pectoral muscle weight across both breeds was observed as they matured,with CC outpacing RR in terms of weight at each stage of development.Differential expression analysis identified 398 and 1,129 genes in the two dimensions of breeds and ages,respectively.A total of 75,149 ATAC-seq peaks were annotated in promoter,exon,intron and intergenic regions,with a higher number of peaks in the promoter and intronic regions.The age-biased genes and breed-biased genes of RNA-seq were combined with the ATAC-seq data for subsequent analysis.The results spotlighted the upregulation of ACTC1 and FDPS at D21,which were primarily associated with muscle structure development by gene cluster enrichment.Additionally,a noteworthy upregulation of MUSTN1,FOS and TGFB3 was spotted in broiler chickens at D42,which were involved in cell differentiation and muscle regeneration after injury,suggesting a regulatory role of muscle growth and repair.Conclusions This work provided a regulatory network of postnatal broiler chickens and revealed ACTC1 and MUSTN1 as the key responsible for muscle development and regeneration.Our findings highlight that rapid growth in broiler chickens triggers ongoing muscle damage and subsequent regeneration.These findings provide a foundation for future research to investigate the functional aspects of muscle development.
基金funded by the National Natural Science Foundation of China(42107476,31901241)the China Postdoctoral Science Foundation(2020M682600)+1 种基金the China Postdoctoral International Exchange Fellowship Program(PC2021099)the Natural Science Foundation of Hunan Province(2021JJ41075).
文摘Trees progress through various growth stages,each marked by specific responses and adaptation strate-gies to environmental conditions.Despite the importance of age-related growth responses on overall forest health and management policies,limited knowledge exists regarding age-related effects on dendroclimatic relationships in key subtropical tree species.In this study,we employed a den-drochronological method to examine the impact of rapid warming on growth dynamics and climatic sensitivity of young(40–60 years)and old(100–180 years)Pinus mas-soniana forests across six sites in central-southern China.The normalized log basal area increment of trees in both age groups increased significantly following rapid warming in 1984.Trees in young forests further showed a distinct growth decline during a prolonged severe drought(2004–2013),whereas those in old forests maintained growth increases.Tree growth was more strongly influenced by temperature than by moisture,particularly in old forests.Spring tem-peratures strongly and positively impacted the growth of old trees but had a weaker effect on young ones.Old forests had a significantly lower resistance to extreme drought but faster recovery compared to young forests.The“divergence problem”was more pronounced in younger forests due to their heightened sensitivity to warming-induced drought and heat stress.With ongoing warming,young forests also may initially experience a growth decline due to their heightened sensitivity to winter drought.Our findings underscore the importance of considering age-dependent changes in forest/tree growth response to warming in subtropical forest man-agement,particularly in the context of achieving“Carbon Peak&Carbon Neutrality”goals in China.
基金supported by the National Science Foundation under grant DMR#2320355supported by the Department of Energy,Office of Science,Basic Energy Sciences,under Award#DESC0022305(formulation engineering of energy materials via multiscale learning spirals)Computing resources were provided by the ARCH high-performance computing(HPC)facility,which is supported by National Science Foundation(NSF)grant number OAC 1920103。
文摘Magnesium alloys are emerging as promising alternatives to traditional orthopedic implant materials thanks to their biodegradability,biocompatibility,and impressive mechanical characteristics.However,their rapid in-vivo degradation presents challenges,notably in upholding mechanical integrity over time.This study investigates the impact of high-temperature thermal processing on the mechanical and degradation attributes of a lean Mg-Zn-Ca-Mn alloy,ZX10.Utilizing rapid,cost-efficient characterization methods like X-ray diffraction and optical microscopy,we swiftly examine microstructural changes post-thermal treatment.Employing Pearson correlation coefficient analysis,we unveil the relationship between microstructural properties and critical targets(properties):hardness and corrosion resistance.Additionally,leveraging the least absolute shrinkage and selection operator(LASSO),we pinpoint the dominant microstructural factors among closely correlated variables.Our findings underscore the significant role of grain size refinement in strengthening and the predominance of the ternary Ca_(2)Mg_(6)Zn_(3)phase in corrosion behavior.This suggests that achieving an optimal blend of strength and corrosion resistance is attainable through fine grains and reduced concentration of ternary phases.This thorough investigation furnishes valuable insights into the intricate interplay of processing,structure,and properties in magnesium alloys,thereby advancing the development of superior biodegradable implant materials.