Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs worldwide.Due to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more prevalent.Glaucoma primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

Relationship between number of passing events and operating parameters in mixed bicycle traffic

This paper investigates the passing events between electric bicycles and conventional bicycles and explores the relationships between passing events and traffic parameters in bicycle facilities.Three exclusive bicycle paths in Nanjing, China,were observed with cameras.Then,the field data including vehicle number,velocity characteristics and passing event features were analyzed in detail.Data analysis and fitting reveal that the speed difference has little impact on the passing event number,as does the bicycle ratio.The Gaussian function can better describe the relationship between the passing event number and bicycle volume （density）.The valid use level of bicycle path width influences the inflexion of the passing events-density fitting curve.The conclusions can be applied for estimating the passing events in mixed bicycle flows and for choosing a suitable width of separate bicycle path.

QIM digital watermarkingbased on LDPC code and messagepassingunder scalingattacks

Watermarking system based on quantization index modulation （QIM） is increasingly popular in high payload applications,but it is inherently fragile against amplitude scaling attacks.In order to resist desynchronization attacks of QIM digital watermarking,a low density parity check （LDPC） code-aided QIM watermarking algorithm is proposed,and the performance of QIM watermarking system can be improved by incorporating LDPC code with message passing estimation/detection framework.Using the theory of iterative estimation and decoding,the watermark signal is decoded by the proposed algorithm through iterative estimation of amplitude scaling parameters and decoding of watermark.The performance of the proposed algorithm is closer to the dirty paper Shannon limit than that of repetition code aided algorithm when the algorithm is attacked by the additive white Gaussian noise.For constant amplitude scaling attacks,the proposed algorithm can obtain the accurate estimation of amplitude scaling parameters.The simulation result shows that the algorithm can obtain similar performance compared to the algorithm without desynchronization.

Gaussian Mixture-Learned Approximate Message Passing(GM-LAMP)Based Hybrid Precoders for mmWave Massive MIMO Systems

Hybrid precoder design is a key technique providing better antenna gain and reduced hardware complexity in millimeter-wave(mmWave)massive multiple-input multiple-output(MIMO)systems.In this paper,Gaussian Mixture learned approximate message passing(GM-LAMP)network is presented for the design of optimal hybrid precoders suitable for mmWave Massive MIMO systems.Optimal hybrid precoder designs using a compressive sensing scheme such as orthogonal matching pursuit(OMP)and its derivatives results in high computational complexity when the dimensionality of the sparse signal is high.This drawback can be addressed using classical iterative algorithms such as approximate message passing(AMP),which has comparatively low computational complexity.The drawbacks of AMP algorithm are fixed shrinkage parameter and non-consideration of prior distribution of the hybrid precoders.In this paper,the fixed shrinkage parameter problem of the AMP algorithm is addressed using learned AMP(LAMP)network,and is further enhanced as GMLAMP network using the concept of Gaussian Mixture distribution of the hybrid precoders.The simula-tion results show that the proposed GM-LAMP network achieves optimal hybrid precoder design with enhanced achievable rates,better accuracy and low computational complexity compared to the existing algorithms.

Turbo Message Passing Based Burst Interference Cancellation for Data Detection in Massive MIMO-OFDM Systems

This paper investigates the fundamental data detection problem with burst interference in massive multiple-input multiple-output orthogonal frequency division multiplexing(MIMO-OFDM) systems. In particular, burst interference may occur only on data symbols but not on pilot symbols, which means that interference information cannot be premeasured. To cancel the burst interference, we first revisit the uplink multi-user system and develop a matrixform system model, where the covariance pattern and the low-rank property of the interference matrix is discussed. Then, we propose a turbo message passing based burst interference cancellation(TMP-BIC) algorithm to solve the data detection problem, where the constellation information of target data is fully exploited to refine its estimate. Furthermore, in the TMP-BIC algorithm, we design one module to cope with the interference matrix by exploiting its lowrank property. Numerical results demonstrate that the proposed algorithm can effectively mitigate the adverse effects of burst interference and approach the interference-free bound.

Evaluation of the Impact of Refined Quality Control Management Model on the Qualified Rate of Disinfection and Sterilization of Surgical Instruments in the Sterilization Supply Center

Objective:To evaluate the application value of a refined quality control management model for a sterilization supply center.Methods:A retrospective analysis was conducted on the work situation of the sterilization supply center from January 2021 to January 2023.The work situation before January 31,2022,was classified as the control group;a routine quality control management model was implemented,and the work situation after January 31,2022,was classified as the observation group.The quality of medical device management and department satisfaction between the two groups were compared.Results:The timely recovery and supply rate,classification and cleaning pass rate,disinfection pass rate,packaging pass rate,sterilization pass rate,and department satisfaction score in the observation group were all higher than those of the control group(P<0.05).Conclusion:Implementing a refined quality control management model in the sterilization supply center can improve the quality management level of medical devices and department satisfaction and is worthy of promotion.

Enhanced Steganalysis for Color Images Using Curvelet Features and Support Vector Machine

Algorithms for steganography are methods of hiding data transfers in media files.Several machine learning architectures have been presented recently to improve stego image identification performance by using spatial information,and these methods have made it feasible to handle a wide range of problems associated with image analysis.Images with little information or low payload are used by information embedding methods,but the goal of all contemporary research is to employ high-payload images for classification.To address the need for both low-and high-payload images,this work provides a machine-learning approach to steganography image classification that uses Curvelet transformation to efficiently extract characteristics from both type of images.Support Vector Machine(SVM),a commonplace classification technique,has been employed to determine whether the image is a stego or cover.The Wavelet Obtained Weights(WOW),Spatial Universal Wavelet Relative Distortion(S-UNIWARD),Highly Undetectable Steganography(HUGO),and Minimizing the Power of Optimal Detector(MiPOD)steganography techniques are used in a variety of experimental scenarios to evaluate the performance of the proposedmethod.Using WOW at several payloads,the proposed approach proves its classification accuracy of 98.60%.It exhibits its superiority over SOTA methods.

Efficient Recovery of Structured Sparse Signals via Approximate Message Passing with Structured Spike and Slab Prior

Due to limited volume, weight and power consumption, micro-satellite has to reduce data transmission and storage capacity by image compression when performs earth observation missions. However, the quality of images may be unsatisfied. This paper considers the problem of recovering sparse signals by exploiting their unknown sparsity pattern. To model structured sparsity, the prior correlation of the support is encoded by imposing a transformed Gaussian process on the spike and slab probabilities. Then, an efficient approximate message-passing algorithm with structured spike and slab prior is derived for posterior inference, which, combined with a fast direct method, reduces the computational complexity significantly. Further, a unified scheme is developed to learn the hyperparameters using expectation maximization(EM) and Bethe free energy optimization. Simulation results on both synthetic and real data demonstrate the superiority of the proposed algorithm.

Aerodynamic performances and vehicle dynamic response of high-speed trains passing each other

Based on the aerodynamics and vehicle dynamics, the aerodynamic performances and vehicle dynamic characteristics of two high-speed trains passing each other on the ground, embankment and bridge are studied. Firstly, a train aerodynamic model and a vehicle dynamic model are established. Through the simulation of the two models, the pressure waves, aerodynamic forces, and vehicle dynamic responses are obtained. Then, the pressure waves and aero- dynamic forces on different foundations are compared. The results show that the variation trends of pressure wave and aerodynamic forces of trains passing each other on different foundations are almost similar. The peak-to-peak differ- ences in pressure wave and aerodynamic force are below 4% and 3% in three cases in open air. Besides, the differences of security indexes, including coefficient of derailment, wheel unloading rate, the wheelset lateral force, and the wheel- rail vertical force, are below 2% among the three cases; the differences of comfort indexes, including the lateral acceleration and the vertical acceleration, are also below 2%. It is concluded that the dynamic performances of trains pass- ing each other are influenced little by different foundations in open air.

Superlinear Fourth-order Elliptic Problem without Ambrosetti and Rabinowitz Growth Condition

This paper deals with superlinear fourth-order elliptic problem under Navier boundary condition. By using the mountain pass theorem and suitable truncation, a multiplicity result is established for all λ〉 0 and some previous result is extended.

Origin of Mountain Passes across Continental Divide Segments Surrounding the Southwest Montana Big Hole and Beaverhead River Drainage Basins, USA

The evolution of southwest Montana’s Big Hole and Beaverhead River drainage basins is determined from topographic map evidence related to mountain passes crossing what are today high altitude drainage divides including North America’s east-west Continental Divide. Map evidence, such as orientations of valleys leading away from mountain passes (and saddles) and barbed tributaries found along the downstream drainage routes, is used to reconstruct flow directions of streams and rivers that once crossed the present-day high mountain divides. Large south-oriented anastomosing complexes of diverging and converging channels are interpreted to have eroded what are today closely spaced passes and saddles now notched into high mountain ridges. Water in those south-oriented channels is interpreted to have flowed across emerging mountains and subsiding basins. Headward erosion of deeper southeast-oriented valleys, assisted by crustal warping, concentrated south-oriented water in fewer and deeper valleys as the water flowed from southwest Montana into what are today Idaho and the Snake River drainage basin. Headward erosion of the Big Hole River valley between the emerging Anaconda and Pioneer Mountains, also assisted by crustal warping, reversed all Big Hole Basin drainage so as to create the north-, east-, and south-oriented Big Hole River drainage route. A final and even more major reversal of flow in the present-day north-oriented Montana Missouri River valley, with the assistance of additional crustal warping, next ended all remaining flow to Idaho and the Snake River drainage basin and reversed and captured all drainage in the present-day north-oriented Big Hole, Beaverhead, and Red Rock River drainage basins. The observed map evidence indicates that prior to the final flow reversal events, large volumes of south-oriented water flowed across southwest Montana’s Big Hole and Beaverhead River drainage basins.

Going Green and Smart

Two sets of energy data from China have received widespread attention recently:the share of renewable energy in China’s total installed power generation capacity climbed to 53.8 percent in the first half of this year,after surpassing thermal power’s share last year;and in July,China’s new-energy vehicles outsold fuel-powered passenger cars on a monthly basis for the first time.The two breakthroughs have once again brought China’s push for green transformation to the fore.

The two-way feedback and passing-way of human body

Two-way feedback of human body was published in 1992. The sensation of two-way feedback of body is a special system of human reaction, which maintains and regulates symmetry and balance of human body. The human two-way feedback reacts to human health. For human overall health and delay decrepitude, it is necessary to pay attention to the stimulations (passive acceptance and initiative interventions) and relevant influences in human body and the stimulative effect. In this paper, the experimental research of stimulation and an example of two-way feedback in human body are given. And lay a foundation of prevention, medical treatment and hygiene of human overall health.

Notch formation in vertical excavations in a deep hard rock mine and rock stabilization methodologies

This paper presents details of the early to mid-stage deterioration in the form of notch growth of two 3 m diameter bored raises that were excavated and slashed to 7.8 m to serve as an internal shaft(winze).In addition,the long-term deterioration of a series of ore/waste passes that were excavated with the bottom-up Alimak methodology is investigated.These excavations were completed at depths between 1200 and 1915 m below the surface in a hard rock mine in Sudbury,Ontario,Canada.The ability to see a cross-section of fracturing around the bored raises while slashing into them and observing the progressive growth of fractures was critical for understanding the factors leading to deterioration.The Alimak-driven ore/waste passes were in an advanced state of deterioration,which provided a late-stage notch growth profile that could be compared with the notch growth observed in the bored raises.The methods used to support and stabilize these excavations are detailed;in addition,methodologies to prevent some of the deterioration from occurring are also presented.The findings of this work are useful for understanding the mechanisms driving brittle rock failure in deep mining and subsequently for minimizing or preventing the deterioration from occurring.

Study on Optimizing of Ball Passing Strategy and Role Switching Mechanism for Robot Soccer

A new ball passing strategy for robot soccer is proposed in this paper. With introduce of a new algorithm on ball passing, the optimum strategy is confirmed to be more efficient and exact when passing a ball. Questions of role switching in multi-intelligent agent cooperation in robot soccer are described based on Generalized Stochastic Petri-Net （GSPN）. Results of computer simulation have confirmed the feasibility and efficiency of above Petri-net method.

Glia-to-neuron reprogramming to the rescue?

Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative medicine.The brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be changed.An exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.

4-15 Energy Deposition and Excitation of Wake eld in Case of 100 keV/u Ion Beam Passing through a Plasma Target

Recently our team investigated the energy deposition and excitation of wakefield in case of hundreds keV proton/helium ion beams passing a gas-discharged plasma target. The plasma target was produced by igniting an electric discharge of hydrogen gas in two-collinear quartz tubes, each of 5 mm in diameter and 78 mm in length, the electrical current even up to kA will flow in two opposite directions in either of the two quartz tubes.

Comparing of the Passing Experience of Clare in Quicksand and Passing and Birdie in Caucasia

This article aims at comparing and contrasting the passing experience of Clare in Larsen Nella’s Quicksand and Passing and Birdie in Danzy Senna's Caucasia.These two characters both have light skin and look white.They both try to pass to the privileged identity(White for Clare;Black for Birdie)and they suffer and struggle on the edge of the color line.The author believes that these two characters are victims of the society divided by race.For people with biracial identity,their experience of having to adopt the privileged identity and giving up who they really are can be extremely painful.

Impact and Management under Extracorporeal Circulation of a Patient with Renal Insufficiency on Dialysis with a High-Flow Arteriovenous Fistula in the Cardiac Surgery Department of the Angers Teaching Hospital about a Case and Review of the Literature

Arteriovenous fistulas have a substantial impact on systemic hemodynamics, however their effect on extracorporeal circulation is not well understood. We report our clinical observation on the management under extracorporeal circulation of a patient with renal insufficiency with a high-flow arteriovenous fistula. This is a 59-year-old man who was referred to us for surgical treatment of ischemic coronary artery disease in a context of anuric chronic renal failure. Hypothermia at 32°C is started from the start in CEC due to hyperflow at the level of the arteriovenous fistula. We performed two coronary artery bypasses of the marginal and IVA via the two internal thoracic arteries. The patient is hemofiltered in order to avoid hyperkalaemia and possibly avoid fluid overload related to filling per CEC. The clamping time was 71 minutes and the SCC lasted 141 minutes. There was no homologous transfusion in the operating room. It turns out that the input/output balance is zero at the end of the CEC. The postoperative course was simple.

基于RFieldbus的Token-Passing协议实时性能建模

RFieldbus 无线现场总线的 MAC 协议 Token Passing 可看成是一个多台多队列排队系统。在分析了 TTR(令牌目的循环时间)对 RFieldbus 中 3 个优先级队列的服务时间的动态限制后,多台单队列排队模型 RF-P 被提出。对从站的轮巡交换数据任务被转化为RF-P 中的令牌内走步时间,原有的高、低级别两个队列则化成了两个具有不同 Poisson 到达率的 M/G/1/∞服务台。利用排队论中的准守恒 PCL 定律,在将服务时间限制转换为数量限制后,求出了等待响应时间的数学解析式。与试验结果的比较表明,在负载不大于 60%时其偏差度约在 10-20%间。