选择性凝血因子XI抑制剂在血栓性疾病治疗中的临床研究进展

血栓性疾病是当今社会的一个重要医疗问题,动脉内血栓形成是引起心肌梗死、缺血性脑卒中、急性肢体缺血的最常见原因,静脉内血栓则可能导致肢体缺血坏死及肺栓塞等严重后果,这些疾病每年共导致全球1000多万人死亡,占所有疾病死亡的50%以上,在过去的20年内,这一比例更是增加了25%~35%[1]。目前,抗凝剂是预防和治疗血栓形成的主要手段之一。

System and Realization Path of Xi Jinping's Eco-poverty Alleviation Concept under the Vision of Green Development

Since the 18 th National Congress of the Communist Party of China,General Secretary Xi Jinping delivered a series of speeches on ecological environment and poverty governance,forming the Xi Jinping's eco-poverty alleviation ideology.In this paper,the Xi Jinping's eco-poverty alleviation ideology is taken as the research object.Using the methods of literature analysis and comparative analysis,the origin of eco-poverty alleviation theory is explored from the common prosperity theory and the theory of ecological capital,and the practice foundation is found out from practical cases.The relationship between the ecological damage and poverty is systematically analyzed,and the mechanism of ecological poverty is explored in detail.The basic connotation of Xi Jinping's eco-poverty alleviation is expounded,and it consists of three parts:guiding ideology layer,implementation layer,and guarantee layer.By perfecting and innovating the market mechanism,social management mechanism,performance evaluation mechanism,integration mechanism with other poverty alleviation methods,and ecological immigration mechanism of ecological poverty,the realization of Xi Jinping's eco-poverty alleviation concept could be guaranteed.

English Translation of Chinese Natural Ecological Discourse:A Corpus-based Case Study on Xi Jinping:The Governance of China

Amid the increasingly severe global natural eco-environment,it is necessary to build a natural ecological civilization by constructing an ecological civilization discourse.Against this background,this study compiles a corpus of natural ecological discourse in the English translation of Xi Jinping:The Governance of China(short for Xi).By using Wordsmith and AntConc,this study explores the linguistic features of the ecological discourse in English translation of Xi in the following dimensions,including high-frequency words,keywords,word collocations,concordance lines.This study aims to analyze the concepts and attitudes towards natural ecology,so as to provide certain valuable insights for the construction of China’s discourse on natural ecological civilization.The study found that the natural ecology discourse involving in the English translation of Xi turned out to be ecologically beneficial.

达芬奇机器人(Xi)辅助下直肠前切除术(NOSES-Ⅳ式)

达芬奇机器人(Xi)系统联合经自然腔道取标本(NOSES)在直肠癌手术中的应用日益成熟和普遍.二者的结合充分发挥了各自的优势,将层面的游离,淋巴的清扫,血管的解剖,神经的保护和无菌、微创理念贯穿始终.因此,机器人下的手术操作,规范的手术流程,经自然腔道取标本的微创模式,为程序化的直肠癌根治手术带来了新的进步.

达芬奇Xi系统机器人辅助后腹腔镜肾上腺切除术治疗肾上腺肿瘤的疗效观察

目的 探讨达芬奇Xi系统机器人辅助后腹腔镜肾上腺切除术治疗肾上腺肿瘤的临床效果。方法 选取2019年1月至2022年1月河北省唐山市人民医院收治并经病理确诊的肾上腺肿瘤患者97例进行回顾性研究,根据治疗方法分为机器人手术组46例(采用达芬奇Xi系统机器人辅助后腹腔镜肾上腺切除术治疗)和传统腹腔镜手术组51例(采用传统后腹腔镜肾上腺切除术治疗)。比较两组手术相关指标,统计两组并发症情况、随访情况。结果 两组术中出血量、手术时间比较,差异无显著性(P>0.05);与传统腹腔镜手术组相比,机器人手术组肿瘤直径较大,中转开腹率、术后出血率降低,术后止痛剂使用次数更少,术后引流时间、术后住院时间、下床活动时间及术后胃肠功能恢复时间明显缩短,住院费用有所增加,差异有显著性(P<0.05)。与传统腹腔镜手术组相比较,机器人手术组术中并发症发生率明显降低,差异有显著性(P<0.05),而两组术后并发症发生率、术后血压改善情况、肿瘤复发率、是否需长期口服激素差异无显著性(P>0.05)。结论 达芬奇Xi系统机器人辅助后腹腔镜肾上腺切除术治疗肾上腺肿瘤,手术创伤小,术中并发症发生率低,患者恢复快,且不增加手术时间。

From Hai Yao, Yang Yao to Xi Yao: Sinification of Material Medical from the West

In ancient China, Daoist philosophers developed the concepts of qi(energy), Wu Xing(five elements), and yin(feminine, dark, negative) and yang(masculine, bright, positive) opposite forces between 200 and 600 BCE. Based on these philosophies, Zhen Jiu(acupuncture), Ben Cao(materia medica), and the practice of Qi Gong(energy optimization movements) evolved as the three interrelated therapeutic regimens of Chinese medicine(Note 1). Since the time of Zhang Qian, who discovered China's western regions in the 1st century BCE, Hai Yao(the exotic elements of materia medica from the maritime Silk Road countries), had been transmitted from the ancient land and maritime routes of the Silk Road to China in the past two millennia(Note 2). Since the late 17th century, the English East India Company, later called the British East India Company, introduced Yang Yao(opium) to the Manchu Qing Empire to balance a growing trade deficit for tea export from China to the British Empire. After the First Opium War ended in 1842, enterprising expatriate chemists and druggists in the treaty ports imported Xi Yao(modern medicines from the Western world) for sale to the merchant navy and the local market. From the second half of the 19th century onwards, both Hai Yao and Xi Yao have become a fully integrated part of modern China's armamentarium for the Chinese medicine and Western hospitals and retail pharmacy sectors. This paper articulates the journey of adoption of exotic elements of materia medica from the ancient land and sea routes of the Silk Road, including the western regions and the rest of the world in the past two millennia. Opium traders, ship surgeons, medical and pharmaceutical missionaries, enterprising traders, and policymakers together transformed Ben Cao into Xi Yao during the late Manchu Qing dynasty and the early Nationalist Era.

达芬奇Xi机器人在单侧腋窝入路免充气甲状腺手术中的临床应用分析

背景和目的:2007年,Kang等第1次将机器人手术应用于甲状腺,之后机器人甲状腺手术在全球范围内开展。因安全性、肿瘤治疗的根治性和美容性不断得到验证,腋窝入路比例在国内正在快速增长。本研究通过对比分析使用达芬奇Xi机器人完成的95例单侧腋窝入路免充气甲状腺手术与91例传统手术治疗cN0期甲状腺微小乳头状癌(papillary thyroid microcarcinoma,PTMC)的临床疗效,探讨达芬奇Xi机器人单侧腋窝入路手术治疗PTMC的优势及临床应用价值。方法:回顾性分析2020年3月—2021年11月复旦大学附属肿瘤医院头颈外科收治的186例cN0期单侧单灶PTMC患者的临床数据,根据手术方式分为机器人组(95例)和开放组(91例),分析比较两组患者的一般临床资料、手术结果、术后并发症、切口满意度、学习曲线及手术费用等情况。结果:两组患者在性别、年龄、是否合并桥本甲状腺炎、肿瘤直径及病灶位置方面差异无统计学意义(P>0.05)。机器人组手术时间[(126.65±34.76)min]长于开放组[(60.99±21.12)min],在经历36例手术后手术时间可达稳定水平。手术费用[(47940.66±4404.30)元]高于开放组[(15807.73±2295.35)元]。在术中出血量[机器人组:(20.48±18.83)mL;开放组:(16.15±13.95)mL]、清扫淋巴结个数[机器人组:(2.61±2.77)枚;开放组:(2.97±2.20)枚]和检出阳性淋巴结个数[机器人组:(1.01±1.61)枚;开放组:(0.78±1.36)枚]方面差异无统计学意义(P>0.05)。机器人组术后暂时性声嘶(1.10%)低于开放组(2.20%),但差异无统计学意义(P>0.05)。机器人组术后切口满意度(非常满意87.4%,比较满意11.6%)高于开放组(非常满意71.4%,比较满意26.4%),差异有统计学意义(P<0.05)。结论:达芬奇Xi机器人单侧腋窝入路免充气甲状腺手术不仅具有良好的美容效果,较高的患者满意度,而且学习曲线短,术中出血量、淋巴结检测情况及术后并发症发生情况与传统手术相当。

Spatiotemporal Evolution Characteristics of Urban Land Surface Temperature Based on Local Climate Zones in Xi’an Metropolitan,China

Local climate zones(LCZs)are an effective nexus linking internal urban structures to the local climate and have been widely used to study urban thermal environment.However,few studies considered how much the temperature changed due to LCZs transformation and their synergy.This paper quantified the change of urban land surface temperature(LST)in LCZs transformation process by combining the land use transfer matrix with zonal statistics method during 2000–2019 in the Xi’an metropolitan.The results show that,firstly,both LCZs and LST had significant spatiotemporal variations and synchrony.The period when the most LCZs were converted was also the LST rose the fastest,and the spatial growth of the LST coincided with the spatial expansion of the built type LCZs.Secondly,the LST difference between land cover type LCZs and built type LCZs gradually widened.And LST rose more in both built type LCZs transferred in and out.Finally,the Xi’an-Xianyang profile showed that the maximum temperature difference between the peaks and valleys of the LST increased by 4.39℃,indicating that localized high temperature phenomena and fluctuations in the urban thermal environment became more pronounced from 2000 to 2019.

A Comparative Study of YīJiàn Xiǎo Shìand A Small Incident Rendered by the Yangs

Lu Xun’s short stories play a prominent role in the history of modern Chinese literature,and a number of Sinologists have studied them and published their English translations.This paper selects“YīJiàn Xiǎo Shì”in Lu Xun’s collection“Call to Arms”as the object of study,taking hypotaxis and parataxis as the starting point,and compares the translation of Yang Hsien-yi and Gladys Yang with the original version,studying the differences between the them in the process of C-E translation.It is hoped that some flexible conversion strategies in English-Chinese translation can be learned from the translation research.

The Study on Tourist Destination Tourism Image Perception and Evaluation in Xi'an City

[Objective] The aim was to explore the tourist destination image measurement method, and have an empirical study on Xi＇an City. [Method] With combination of non-structural and structured approach to design questionnaires, tourism image of Xi＇an was explored using the SPSS software from both the qualitative and quantitative analyses. [Result] Xi＇an tourism images serve a heritage historical monuments atmosphere with the Terracotta Warriors, City Wall, Big Wild Goose Pagoda,Huaqing Hot Springs, presenting a positive feeling among tourists in general. In the dissemination of travel, tourism infrastructure construction, tourism transportation,travel services have negative effects on the image of Xi＇an tourism. [Conclusion]The evaluation on the tourism resources is highly spoken of by tourists than the scenic spot, indicating that despite high visibility of tourism resources in Xi＇an, it has not formed strong core competitiveness and a complete tourism industrial chain. It is necessary to take the right marketing strategies to enhance tourist familiarity to Xi＇an. Tourists demands, therefore, should be well considered in developing Xi＇an scenic spots and new tourism products and projects be focused on to improve tourists＇ satisfaction.

牛凝血因子XI基因15bp插入突变的分子检测及基因频率分析

牛凝血因子XI基因第9外显子15bp插入突变是近年在日本和牛中发现的一种遗传缺陷,导致凝血因子活性降低。为了分析该缺陷基因在我国牛群中的携带频率,本研究开发了能灵敏检测该突变的2种新方法,即毛细管电泳法和等位基因特异性扩增法,并检测了我国引进的和牛种公牛、1个含和牛血液的杂交育种群和商品群、4个国内地方品种(鲁西牛、延边牛、蒙古牛、复州牛)、2个培育品种(中国荷斯坦牛、新疆褐牛)和6个国外品种(西门塔尔、夏洛来、利木赞、安格斯、蒙贝利亚、挪威红牛)样品共452头份。结果显示,在和牛、含和牛血液的杂交育种群及商品群中突变基因频率分别为0.182、0.389和0.242,在延边牛中发现1头携带者,而在其余群体中均未检出,推测该突变可能只存在于东北亚和我国东北地区牛群中。今后我国在引进和牛用于杂交改良以及本地牛选育中需要对该突变进行分子检测和逐步淘汰,从而降低不利等位基因的频率。

Development Strategies for Modern Agricultural Logistics in Xi'an Based on Systematic Diynamics

[Objective] The devlopmental stratagies for modern agricultural logistics industry in Xi’an were studied based on system dynamics.[Method] By dint of system dynamics,reality analysis and relevant data were applied to support the exploration of each factor for the development of modern agricultural logistics industry.In the meantime,according to the concrete data,the systematic dynamics model was set up based on the third party logistics and Xi’an agricultural economy cooperation.In addition,each influencing factor was expounded.[Result] The agricultural production,logistics requirement and logistics supply in Xi’an City were increasing;the idea of reducing the cost through improving agricultural logistics requirement was not ideal;the increasing input to agricultural logistics can reduce cost and can promote the development of economy;the third party increasing investment can reduce cost and accelerate economic development.[Conclusion] It provided theoretical basis for the adjustment of economic structure.

The Preliminary Study of Certain Pharmacological Effects of Xi Xin Oil

细辛油能松弛兔离体主动脉条,使去甲肾上腺素所致主动脉收缩的量效曲线右移并效能降低;使离体兔耳灌流量减少;能延长小鼠常压耐缺氧时间;用其1/2 LD_(50)之剂量腹腔注射给药3天,可致小鼠骨髓微核形成增加。

Key Points in the Supervision of Road Landscaping Project——A Case Study of the South 3^(rd) Ring Road in Yanta District of Xi'an City,China

Characteristics of road landscaping were analyzed,as a kind of "linear" landscaping,it could be classified into urban street landscaping,urban ring road and expressway landscaping.Differences between road landscaping projects and other garden landscaping projects or construction projects were analyzed.Landscaping project for the South 3rd Ring Road of Xi'an City(in Yanta District)was taken for an example to summarize construction experience,discuss present conditions and features of garden landscaping supervision in China.The artistic and physiological properties of garden landscaping,as well as the supervision during maintenance period were stressed,but it was also pointed out that garden landscaping supervision in China was actually not given sufficient attention.On this basis,key points in the supervision of road landscaping project were proposed:understanding design ideas,selection of landscape plants,quality control of concealed works,prevention and control of diseases and insects,construction safety management and overall image;only by effectively implementing these key points,a high-quality road landscaping project could be realized to improve the image of a city and beautify its environment.

A Tentative Study on the Combination of Site Protection and City Construction of Xi'an

The protection of relic sites helps determine the culture coordinate of a city or a region,and enhances its cultural image and status.Through analyzing the construction features and technical means of various ruins parks in Xi'an including Daming Palace National Heritage Park,Qujiangchi Ruins Park,Hanyao Ruins Park,Dacien Temple Ruins Park,Tang Dynasty City Wall Ruins Park,Emperor Qin Ⅱ Mausoleum Ruins Park and so on,a new model combining the site protection with city construction is presented.By integrating cultural relics preservation,heritage protection with innovation,a series of ruins parks processed with deep cultural connotation are constructed,which not only protects the relics and refreshes the city construction,but also well reflects the essence of traditional Chinese culture unique charm of ancient oriental civilization.The well combination of site protection and city construction improves the cultural image and status of the city,enhances the charm of public cultural space,promotes the development of heritage protection and secures more funds for urban and rural construction.

4种鬼针草与Xi莶草的TLC鉴别研究

利用ＴＬＣ的方法对４种鬼针草及Ｘｉ莶草进行了鉴别研究，为它们的准确鉴别提供依据。

Protection of Historic and Cultural Heritage in the Urban Renewal of Xi'an City,China

Concept of urban renewal was elaborated,which for the protection of historic and cultural heritage not only provides a favorable opportunity of integrating neighboring environment and improving protection conditions,but also imposes threats such as destroying its historic images and patterns,degrading of survival environment.To properly protect historic and cultural heritage in the unceasing urban renewal,and make it a significant resource and feature of the city but not a barrier of urban development,empirical analysis and theoretical research were adopted to analyze and study current conditions and problems of the protection of historic and cultural heritage in Xi'an City from the dimension of urban renewal concept and present urban renewal of Xi'an.Moreover,through summarizing successful experience of other regions,specific strategies were given to protect historic and cultural heritage of Xi'an City in its urban renewal more scientifically and reasonably.

Analysis on Strategic Future of Application of Agricultural Ecological Source in Control on Agricultural Nonpoint Source Pollution in Xi River Area in Guangxi

Non-point source pollution has become a hot issue on aquatic ecological environment at home and abroad. The research analyzed the challenges confronted by Xi River and proposed to construct agricultural ecological source in middle and upper reaches of the Xi River from the perspectives of scientific layout, legal construction, routine monitoring, technology integration, and coordination system in order to promote sustainable development of eco-environment in Xi River.

Historical Contribution of Socialist Political Economy with Chinese Characteristics

Since the founding of the People's Republic of China,especially after reform and opening up,the Communist Party of China has continuously advanced the Sinicization and modernization of Marxist political economy.Through the great practice of economic construction with Chinese characteristics,a socialist political economy with Chinese characteristics has been formed.As the latest theoretical achievement of Marxist political economy in contemporary China and the 21st-century world,Xi Jinping's economic thought deeply reflects the Communist Party of China's new understanding of the laws of economic development.With more pronounced subjectivity,originality,completeness,and theoretical richness,it not only provides a scientific guide for China's high-quality economic development and the comprehensive construction of a modern socialist country but also propels the socialist political economy with Chinese characteristics to a new stage,contributing Chinese wisdom to the innovative development of Marxist political economy.

基于SAP XI的跨工厂应用整合架构的设计与开发

为解决因系统平台不同造成的跨地区、跨工厂网络信息传输不稳定等问题,利用SAP XI和消息中间件技术构建了跨工厂应用整合架构。该架构以SAP XI作为信息加工转换和接收发送的枢纽,以中烟公司和工厂两级的消息中间件为基础构建传输通道,实现了公司SAP ERP系统与下属各卷烟厂应用系统之间的一体化应用整合。应用效果表明,系统运行稳定可靠,数据处理准确高效,上下行数据传输成功率均为100%,数据传输平均用时分别为1.938 s和0.510 s,满足了业务运转需要,有效提升了企业信息化管理水平。