This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has bee...This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has been made by Chinese in nearly every branches of tissue culture, including in vitro organogenesis, shoot tip culture, anther culture, ovary culture, endosperm culture, protoplast culture as well as mass cell culture. On the basis of reviewing the articles written by Chinese on plant tissue culture, the internationally recognized contributions are specially mentioned. The applications of plant tissue culture to agriculture and industry in China are also introduced.展开更多
Jiuzhaigou National Park, located in northwest plateau of Sichuan Province, is a UNESCO World Heritage Site, and one of the most popular scenic areas in China. On August 8, 2017, a Mw 6.5 earthquake occurred 5 km to t...Jiuzhaigou National Park, located in northwest plateau of Sichuan Province, is a UNESCO World Heritage Site, and one of the most popular scenic areas in China. On August 8, 2017, a Mw 6.5 earthquake occurred 5 km to the west of a major scenic area, causing 25 deaths and injuring 525, and the Park was seriously affected. The objective of this study was to explore the controls of seismogenic fault and topographic factors on the spatial patterns of these landslides. Immediately after the main shock, field survey, remote-sensing investigations, and statistical and spatial analysis were undertaken. At least 2212 earthquake-triggered landslides were identified, covering a total area of 11.8 km^2. Thesewere mainly shallow landslides and rock falls. Results demonstrated that landslides exhibited a close spatial correlation with seismogenic faults. More than 85% of the landslides occurred at 2200 to 3700 m elevations. The largest quantity of landslides was recorded in places with local topographic reliefs ranging from 200 to 500 m. Slopes in the range of ~20°-50° are the most susceptible to failure. Landslides occurred mostly on slopes facing east-northeast(ENE), east(E), east-southeast(ESE), and southeast(SE), which were nearly vertical to the orientation of the seismogenic fault slip. The back-slope direction and thin ridge amplification effects were documented. These results provide insights on the control of the spatial pattern of earthquake-triggered landslides modified by the synergetic effect of seismogenic faults and topography.展开更多
On August 8^(th), 2017, an Ms 7.0 magnitude earthquake occurred in Jiuzhaigou County, northern Sichuan Province, China. The Jiuzhaigou Valley World National Park was the most affected area due to the epicentre being l...On August 8^(th), 2017, an Ms 7.0 magnitude earthquake occurred in Jiuzhaigou County, northern Sichuan Province, China. The Jiuzhaigou Valley World National Park was the most affected area due to the epicentre being located in the scenic area of the park. Understanding the distribution characteristics of landslides triggered by earthquakes to help protect the natural heritage sites in Jiuzhaigou Valley remains a scientific challenge. In this study, a relatively complete inventory of the coseismic landslides triggered by the earthquake was compiled through the interpretation of high-resolution images combined with a field investigation. The results indicate thatcoseismic landslides not only are concentrated in Rize Gulley, Danzu Gully and Zezhawa Gully in the study area but also occur in the front part of Shuzheng Gully along the road network(from the entrance of Jiuzhaigou Valley to Heye Village). The landslides predominantly occur on the east-and southeastfacing slopes in the study area, which is a result of the integrated action of the valley direction and fault movement direction. The back-slope effect and the slope structure caused the difference in coseismic landslide distribution within the three gullies(Danzu Gully, Rize Gully, and Zezhawa Gully) near the inferred fault. In addition, the topographic position index was used to analyse the impact of microlandforms on earthquake-triggered landslides by considering the effect of the slope angle. The study results reveal a higher concentration of landslides in the slope position class of the middle slope(30°-50°) in Jiuzhaigou Valley. These findings can provide scientific guidance for the protection of natural heritage sites and post-disaster reconstruction in Jiuzhaigou Valley.展开更多
Background:Most of previous studies aimed to estimate the effect of nurse staffing on quality of acute hospital care have used stochastic methods and their results are mixed.Objective:To measure the magnitude of effec...Background:Most of previous studies aimed to estimate the effect of nurse staffing on quality of acute hospital care have used stochastic methods and their results are mixed.Objective:To measure the magnitude of effect of nurse-staffing level on increasing quality of acute care services in long-run.Data:The number of practicing nurses'density per 1000 population as the proxy of nurse-staffing level and three Health Care Quality Indicators(HCQI)included 30-day mortality per 100 patients based on acute myocardial infarction(MORTAMIO),hemorrhagic stroke(MORTHSTO)and ischemic stroke(MORTISTO)were collected as a part of ongoing project by OECD.org in panels of 26 OECD countries over 2005-2015 period.Method:Panel data analysis.Results:There were committed relationships from nurse-staffing level to the enhancement of HCQI i.e.1%increase in nurse-staffing level would reduce the rates of patient mortality based on MORTAMIO,MORTHSTO and MORTISTO by 0.65%,0.60%and 0.80%,respectively.Furthermore,the role of nursestaffing level in increasing overall HCQI were simulated at the highest level in Sweden(-3.53),Denmark(-3.31),Canada(-2.59),Netherlands(-2.33),Finland(-2.09),Switzerland(-1.72),Australia(-1.64)and United States(-1.53).Conclusion:A higher proportion of nurses-staffing level is associated with higher quality of acute care services in OECD countries.Also,the nursing characteristics of Sweden,Denmark,Canada,Netherlands,Finland,Switzerland,Australia and United States would be good patterns for other countries to maximize nursing outcomes in the care of patients with acute and life-threatening conditions by reducing the risk of complication,mortality and adverse clinical outcomes.展开更多
AIM To investigate the impact of IL28 B and OAS gene polymorphisms on interferon treatment responses in children with chronic hepatitis B.METHODS We enrolled 52 children(between the ages of 4 and 18) with hepatitis B ...AIM To investigate the impact of IL28 B and OAS gene polymorphisms on interferon treatment responses in children with chronic hepatitis B.METHODS We enrolled 52 children(between the ages of 4 and 18) with hepatitis B e antigen-negative chronic hepatitis B(CHB), who were treated with pegylated interferon alfa for 48 wk. Single nucleotide polymorphisms in the OAS1(rs1131476), OAS2(rs1293747),OAS3(rs2072136), OASL(rs10849829) and IL28B(rs12979860, rs12980275 and rs8099917) genes were studied to examine their associations with responses to IFN treatment in paediatric patients. We adopted two criteria for the therapeutic response, achieving an hepatitis B virus(HBV) DNA level < 2000 IU/m L and normalization of ALT activity(< 40 IU/L). To perform the analyses, we compared the patients in terms of achieving a partial response(PR) and a complete response(CR) upon measurement at the 24-wk posttreatment follow-up. RESULTS The PR and CR rates were 80.8% and 42.3%, respectively. Factors such as age, gender and liver histology had no impact on the type of response(partial or complete). A statistically significant relationship between higher baseline HBV DNA and ALT activity levels and lower rates of PR and CR was shown(P < 0.05). The allele association analysis revealed that only the IL-28 B rs12979860(C vs T) and IL28 B rs12980275(A vs G) markers significantly affected the achievement of PR(P = 0.021, OR = 3.3, 95%CI: 1.2-9.2 and P = 0.014, OR = 3.7, 95%CI: 1.3-10.1, respectively). However, in the genotype analysis, only IL-28 B rs12980275 was significantly associated with PR(AA vs AG-GG, P = 0.014, OR = 10.9, 95%CI: 1.3-93.9). The association analysis for CR showed that the TT genotype of IL28 B rs12979860 was present only in the no-CR group(P = 0.033) and the AA genotype of OASL rs10849829 was significantly more frequent in the noCR group(P = 0.044, OR = 0.26, 95%CI: 0.07-0.88). The haplotype analysis revealed significant associations between PR and CR and OAS haplotype(P = 0.0002 and P = 0.001, respectively), but no association with IL28 B haplotype was observed.CONCLUSION IL28 B and OAS polymorphisms are associated with different clinical outcomes in CHB children treated with interferon.展开更多
In October 2015, an ISIS member speaking fluent Hebrew warned that soon there would be no Jews left in Jerusalem or in the rest of the land called "Israel". The Islamic State in Iraq and Syria (ISIS) will fulfill ...In October 2015, an ISIS member speaking fluent Hebrew warned that soon there would be no Jews left in Jerusalem or in the rest of the land called "Israel". The Islamic State in Iraq and Syria (ISIS) will fulfill this mission according this Salafi-Jihadism group. ISIS ideology holds that it is first necessary to fight against the near enemy (the Arab states) but the last apocalyptic battle will be with the Jews (the far enemy). The purpose of this article is to reveal and present the development of Jew-hatred fi'om al-Qa'ida and up to the present doctrine oflSIS.展开更多
This article presents a case study of the Siam Commercial Bank (SCB) by investigating why and how SCB implemented organizational restructuring during the uncertain economic environment, and gives an overview of the ...This article presents a case study of the Siam Commercial Bank (SCB) by investigating why and how SCB implemented organizational restructuring during the uncertain economic environment, and gives an overview of the Thai commercial bank industry. This article presents and discusses SCB's strategy implementation in its organization during 1997-2010. This case study is aimed to provide some guidelines for other companies in developing and in choosing strategies for their business sustainability in the global change, and in choosing the implementation of their organization structure for competitive markets.展开更多
Until the late 1980s, gastroenterology (GE) was considered a subspecialty of Internal Medicine. Today, GE also incorporates Hepatology. However, Digestive Oncology training is poorly defined in the Hepatogastroenterol...Until the late 1980s, gastroenterology (GE) was considered a subspecialty of Internal Medicine. Today, GE also incorporates Hepatology. However, Digestive Oncology training is poorly defined in the Hepatogastroenterology (HGE)-curriculum. Therefore, a Digestive Oncology curriculum should be developed and this document might be a starting point for such a curriculum. HGE-specialists are increasingly resisting the paradigm in which they play only a diagnostic and technical role in the management of digestive tumors. We suggest minimum endpoints in the standard HGE-curriculum for oncology, and recommend a focus year in the Netherlands for Digestive Oncology in the HGE-curriculum. To produce welltrained digestive oncologists, an advanced Digestive Oncology training program with specific qualifications in Digestive Oncology (2 years) has been developed. The schedule in Belgium includes a period of at least 6 mo to be spent in a medical oncology department. The goal ofthese programs remains the production of well-trained digestive oncologists. HGE specialists are part of the multidisciplinary oncological teams, and some have been administering chemotherapy in their countries for years. In this article, we provide a road map for the organization of a proper training in Digestive Oncology. We hope that the World Gastroenterology Organisation and other (inter)national societies will support the necessary certifications for this specific training in the HGE-curriculum.展开更多
On November 1973, about one month after the cease-fire at the end of the Yom Kippur War, the Arab League decided that the Palestine Liberation Organization (PLO) was the sole representative of the Palestinian people...On November 1973, about one month after the cease-fire at the end of the Yom Kippur War, the Arab League decided that the Palestine Liberation Organization (PLO) was the sole representative of the Palestinian people. This article examines the contribution of the PLO to the war effort of the Arab countries during the Yom Kippur War, the influence of the war upon the Palestinian problem, the Palestinian military contribution to the Arab war effort, Jordan's non-participation in the Yom Kippur War and the Egyptian attempt to include the PLO as the representative of the Palestinian people in future negotiations with Israel and the U.S. which enabled the PLO recognition as the Palestinians sole representative for 30 years.展开更多
Sustainable construction, together with sustainability, is a growing concern in developed countries in order to influence construction organizations to make "achieving sustainability" in their projects a stringent p...Sustainable construction, together with sustainability, is a growing concern in developed countries in order to influence construction organizations to make "achieving sustainability" in their projects a stringent prior objective. North Cyprus is a rapidly developing country with an annual economic growth of 7%. Construction became the leading sector within the economy after the boom in demand for holiday and retirement houses especially from English and German holidaymakers. Due to lack of government policy on sustainability, developers usually use traditional ways of construction, and the lack of an established link with international construction, which would help local developers be aware of the latest technology and sustainable building techniques, is the main challenges for North Cyprus construction sector to develop sustainable construction practices.展开更多
Any enterprise now is a significant part of the world economy both in terms of trade and employment. The performance of a business organisation is in part dependent on the capability of its human resource (HR). The ...Any enterprise now is a significant part of the world economy both in terms of trade and employment. The performance of a business organisation is in part dependent on the capability of its human resource (HR). The knowledge and experience of employees is a source of competitive advantage, however, whether this is realised or not may depend on having the right HR policies. Managers therefore seek to implement best practice, and in multinationals there is the potential for intra-organizational learning across national boundaries. The human being is the most important element in the development process and its ultimate goal. Attention to the management of human affairs and the effort to make man an effective contributing member in the development plans within organizations, is the responsibility of those working in the field of human resources management (HRM) which has become a distinguished field of management worldwide and plays an important role especially in the developing countries. This study discussed personnel management to HRM and how HRM functions.展开更多
A weather station is proposed especially designed for developing countries, and to meet the standards of the international scientific community making research on the earth system. The station would measure in situ se...A weather station is proposed especially designed for developing countries, and to meet the standards of the international scientific community making research on the earth system. The station would measure in situ several ECV (essential climate variables). These data may enable an agricultural breakthrough in countries lacking meteorological infrastructure, help in climate change monitoring, and facilitate diffusion of wind energy. A pre-feasibility analysis is presented. It appears interesting that the station is supplied by a social enterprise. A research to establish the best shelter design using computational fluid dynamics is also reported. The criterion is the accuracy with which the surface air temperature is reproduced inside the shelter. A design following recommendations by the WMO (World Meteorological Organization), a smaller design with identical geometry, and two alternative small designs are analyzed. All four designs are simulated in PVC, natural rubber and wood, with and without white paint coating. The smaller shelters perform better. The influence of the material, dimensions and design is smaller than that of the white paint. Shelters made of PVC or rubber, and/or in alternative designs, may be more interesting if other criteria are considered, like whether logistics, manufacturing, etc. are more sustainable, easier and/or cheaper.展开更多
The study reflects on previous World Bank and FAO reports that made the general recommendation to set both research and extension investment targets in developing countries at 1% of agricultural gross domestic product...The study reflects on previous World Bank and FAO reports that made the general recommendation to set both research and extension investment targets in developing countries at 1% of agricultural gross domestic product (AgGDP). In order to define proxies for country-specific extension investment targets, authors developed an extension investment model (EIM) based on socio-economic macro-indicators (poverty, undernourishment, access to information and population density) and a method to define estimates for cost increases related to climate change. These parameters helped estimating the demand for agricultural extension and investments required for it. Results showed that about half of the 94 developing and emerging countries should spend more than 1% of their respective share of GDP derived from agriculture and about a quarter of the countries, mostly in Africa and South East Asia, need to spend more than 2% of their AgGDP. The paper reveals significant differences in average investment requirements in different regions and shows the additional extension costs related to climate change and other areas that currently lack investment.展开更多
The article surveys the development of the environmental movement in Israel from the establishment of the state through the present day. Based on trends and transformations in the institutional planning system, it app...The article surveys the development of the environmental movement in Israel from the establishment of the state through the present day. Based on trends and transformations in the institutional planning system, it appears that activism by environmental movement organizations in Israel can be divided into three sub-periods: the establishment period, marked by the Sharon Plan, the founding of the Society for the Protection of Nature in Israel and MALRAZ--Council for the Prevention of Noise and Air Pollution in Israel, and the enactment of the Kanovitch Law and the National Parks and Nature Reserves Law (1963). The next phase of institutionalization is characterized by the establishment of designated institutional bodies--the Nature Reserves Authority, the National Parks Authority and the Environmental Protection Service, and their integration into the national planning system. The institutionalization period concludes with the establishment of the Ministry of the Environment (1989) and the transition to the third period, sustainability. Prominent during this period is a trend toward multidimensional proactive environmental planning and policymaking, reaching across many areas and including extensive regulation As far as environmental organizations are concerned, these three periods comprised a framework of cultural action in which they developed, acted and shaped environmental discourse and practice in Israel. Based on other studies, the article offers a model that illustrates the development of the environmental movement while emphasizing the interaction between individual actors, local organizing and national organizations. Finally, some characteristics and insights regarding activism by environmental organizations in Israel are suggested.展开更多
Different positions of the member states of the World Trade Organization (WTO), especially the developed and developing countries and also the United States of America (USA), the European Union (EU), and Japan r...Different positions of the member states of the World Trade Organization (WTO), especially the developed and developing countries and also the United States of America (USA), the European Union (EU), and Japan representatives, were observed during the Doha Round of trade negotiations under the WTO. The problems of agriculture protection in the developed countries, for example in the EU and USA and also in the developing countries, were becoming serious obstacles during the negotiations. Despite the undeniable benefits of the multilateral WTO forum for trade liberalization, the rapid increase of North-South bilateral and multilateral free trade areas (FTAs) begs a systematic explanation for why some forums are prioritized relative to others. The main aim of the article is the presentation of some new aspects of the international business theory in the context of international economy. The article presents the mercantilist tendencies in the international trade policy, the theory of public choice in the foreign trade policy, protectionist pressures in different political systems, the level of protectionist pressures, food producers' pressure, and conflicts between the tendencies to sustainable international trade liberalization and environmental protection.展开更多
The issue of the future of Europe is becoming increasingly important what with the depth of the economic crisis that started in 2008. In addition to a continuous growth in the number of the unemployed, the crisis part...The issue of the future of Europe is becoming increasingly important what with the depth of the economic crisis that started in 2008. In addition to a continuous growth in the number of the unemployed, the crisis particularly emphasizes the chronic level of energy dependence. The energy saving measures ~energy efficiency), diversification of sources (stability of supply), and the creation of substitutes in renewable energy (energy transition), intertwine with administrative measures and form the response of European countries to the growing energy dependence. At the same time, although facing the threatening warming (or cooling) of the Earth, Europe, as a big advocate of reducing CO2 remains passively dependent on NATO (North Atlantic Treaty Organization) policy in the field of defense in the context of energy dependence. However, for the first time after many decades, Europe and America do not have the same energy, and consequently geo-strategic objective: The US has become energy independent while Europe is chronically energy dependent.展开更多
In 2018,the Chinese government identified four municipalities and seven sub-provincial cities for the implementation of the National Drug Pooled Procurement(NDPP)pilot program(the“4+7”policy).In the present study,we...In 2018,the Chinese government identified four municipalities and seven sub-provincial cities for the implementation of the National Drug Pooled Procurement(NDPP)pilot program(the“4+7”policy).In the present study,we analyzed the effects of the“4+7”policy with data of 25 pilot drugs from the National Healthcare Security Administration(NHSA)from the aspects of drug price,volume,and expenditure.After the implementation of the policy,the average price of total and winning drugs was decreased by 54.47%and 73.82%,respectively,while the DDDc of non-winning drugs was decreased by only 1.54%,and the DDDc of uncertificated generic drugs was increased 83.18%.The DDDs indicating the volume of total and winning drugs was increased by 21.18%and 353.98%,respectively,and the DDDs of non-winning drugs was decreased by 61.35%.The costs of total and non-winning drugs were decreased by 44.83%and 61.94%,respectively,and the cost of winning drugs was increased by 18.87%.The“4+7”policy reduced the price and cost of pilot drugs and improved the affordability and accessibility of drugs.However,there were also problems with unexpected excessive price increases of uncertificated generic drugs and relatively high prices of non-winning products.Therefore,we highly suggested promoting the normalization and institutionalization of pooled drug procurement,enhancing the administrative capacity of local procurement platforms,and strengthening monitoring the price of non-winning,especially for the uncertificated generic drugs.展开更多
OBJECTIVE: To supply literature for developing an international standard of auricular acupuncture points. METHODS: Electronic database searches were con- ducted in the Chinese National Knowledge Infra- structure and...OBJECTIVE: To supply literature for developing an international standard of auricular acupuncture points. METHODS: Electronic database searches were con- ducted in the Chinese National Knowledge Infra- structure and VlP, and the Western databases, Pubmed, the National Science and Technology Li- brary, and the German Journal of Acupuncture, from 1990 to April, 2012. We also searched the doc- uments of international symposiums for auricular acupuncture points (AAPs). Keywords were "auricu- lar points", "auricular acupuncture points", "ear points", or "auriculotherapy" RESULTS: Basic and clinical research on AAPs was performed in China, the United States, France, andGermany. Clinical AAP research was done in Italy, Austria, Switzerland, Spain, the UK, Holland, Japan, Russia, and Africa. However, AAP research was not communicated internationally. The World Federa- tion of Acupuncture-Moxibustion Societies recom- mended international standard of auricular acu- puncture points (ISAAPs). Standardized nomencla- ture and locations of AAPs would provide a solid basis to draft an international standard organiza- tion. CONCLUSION: Experts need to find common points from different countries or regions, provide evidence of different ideas, and list the proposal as a recommendation for an international standard.展开更多
文摘This paper looks back to the development of plant tissue culture in China in the last century. Since 1934, tissue culture studies in China has kept up with the international development in the fields. Progress has been made by Chinese in nearly every branches of tissue culture, including in vitro organogenesis, shoot tip culture, anther culture, ovary culture, endosperm culture, protoplast culture as well as mass cell culture. On the basis of reviewing the articles written by Chinese on plant tissue culture, the internationally recognized contributions are specially mentioned. The applications of plant tissue culture to agriculture and industry in China are also introduced.
基金supported by the Key Laboratory Program for Mountain Hazards and Earth Surface Process, CAS (Grant No. KLMHESP17-06)International Science Program-Silk Road Disaster Risk Reduction (Grant No. 131551KYSB20160002)+2 种基金Major International (Regional) Joint Research Project (Grant No.41520104002) Key Research Program of Frontier Sciences,CAS (Grant No. QYZDY-SSWDQC006) 135 Strategic Program of the Institute of Mountain Hazards and Environment, CAS, NO. SDS-135-1701
文摘Jiuzhaigou National Park, located in northwest plateau of Sichuan Province, is a UNESCO World Heritage Site, and one of the most popular scenic areas in China. On August 8, 2017, a Mw 6.5 earthquake occurred 5 km to the west of a major scenic area, causing 25 deaths and injuring 525, and the Park was seriously affected. The objective of this study was to explore the controls of seismogenic fault and topographic factors on the spatial patterns of these landslides. Immediately after the main shock, field survey, remote-sensing investigations, and statistical and spatial analysis were undertaken. At least 2212 earthquake-triggered landslides were identified, covering a total area of 11.8 km^2. Thesewere mainly shallow landslides and rock falls. Results demonstrated that landslides exhibited a close spatial correlation with seismogenic faults. More than 85% of the landslides occurred at 2200 to 3700 m elevations. The largest quantity of landslides was recorded in places with local topographic reliefs ranging from 200 to 500 m. Slopes in the range of ~20°-50° are the most susceptible to failure. Landslides occurred mostly on slopes facing east-northeast(ENE), east(E), east-southeast(ESE), and southeast(SE), which were nearly vertical to the orientation of the seismogenic fault slip. The back-slope direction and thin ridge amplification effects were documented. These results provide insights on the control of the spatial pattern of earthquake-triggered landslides modified by the synergetic effect of seismogenic faults and topography.
基金financially supported by the National Natural Science Foundation of China (Grant No.41520104002)Key Research Program of Frontier Sciences,CAS (Grant No.QYZDY-SSWDQC006)+1 种基金International partnership program of Chinese Academy of Sciences (Grant No.131551KYSB20160002)financial support from the Opening Fund of State Key Laboratory of Hydraulics and Mountain River Engineering (SKHL1609)
文摘On August 8^(th), 2017, an Ms 7.0 magnitude earthquake occurred in Jiuzhaigou County, northern Sichuan Province, China. The Jiuzhaigou Valley World National Park was the most affected area due to the epicentre being located in the scenic area of the park. Understanding the distribution characteristics of landslides triggered by earthquakes to help protect the natural heritage sites in Jiuzhaigou Valley remains a scientific challenge. In this study, a relatively complete inventory of the coseismic landslides triggered by the earthquake was compiled through the interpretation of high-resolution images combined with a field investigation. The results indicate thatcoseismic landslides not only are concentrated in Rize Gulley, Danzu Gully and Zezhawa Gully in the study area but also occur in the front part of Shuzheng Gully along the road network(from the entrance of Jiuzhaigou Valley to Heye Village). The landslides predominantly occur on the east-and southeastfacing slopes in the study area, which is a result of the integrated action of the valley direction and fault movement direction. The back-slope effect and the slope structure caused the difference in coseismic landslide distribution within the three gullies(Danzu Gully, Rize Gully, and Zezhawa Gully) near the inferred fault. In addition, the topographic position index was used to analyse the impact of microlandforms on earthquake-triggered landslides by considering the effect of the slope angle. The study results reveal a higher concentration of landslides in the slope position class of the middle slope(30°-50°) in Jiuzhaigou Valley. These findings can provide scientific guidance for the protection of natural heritage sites and post-disaster reconstruction in Jiuzhaigou Valley.
文摘Background:Most of previous studies aimed to estimate the effect of nurse staffing on quality of acute hospital care have used stochastic methods and their results are mixed.Objective:To measure the magnitude of effect of nurse-staffing level on increasing quality of acute care services in long-run.Data:The number of practicing nurses'density per 1000 population as the proxy of nurse-staffing level and three Health Care Quality Indicators(HCQI)included 30-day mortality per 100 patients based on acute myocardial infarction(MORTAMIO),hemorrhagic stroke(MORTHSTO)and ischemic stroke(MORTISTO)were collected as a part of ongoing project by OECD.org in panels of 26 OECD countries over 2005-2015 period.Method:Panel data analysis.Results:There were committed relationships from nurse-staffing level to the enhancement of HCQI i.e.1%increase in nurse-staffing level would reduce the rates of patient mortality based on MORTAMIO,MORTHSTO and MORTISTO by 0.65%,0.60%and 0.80%,respectively.Furthermore,the role of nursestaffing level in increasing overall HCQI were simulated at the highest level in Sweden(-3.53),Denmark(-3.31),Canada(-2.59),Netherlands(-2.33),Finland(-2.09),Switzerland(-1.72),Australia(-1.64)and United States(-1.53).Conclusion:A higher proportion of nurses-staffing level is associated with higher quality of acute care services in OECD countries.Also,the nursing characteristics of Sweden,Denmark,Canada,Netherlands,Finland,Switzerland,Australia and United States would be good patterns for other countries to maximize nursing outcomes in the care of patients with acute and life-threatening conditions by reducing the risk of complication,mortality and adverse clinical outcomes.
文摘AIM To investigate the impact of IL28 B and OAS gene polymorphisms on interferon treatment responses in children with chronic hepatitis B.METHODS We enrolled 52 children(between the ages of 4 and 18) with hepatitis B e antigen-negative chronic hepatitis B(CHB), who were treated with pegylated interferon alfa for 48 wk. Single nucleotide polymorphisms in the OAS1(rs1131476), OAS2(rs1293747),OAS3(rs2072136), OASL(rs10849829) and IL28B(rs12979860, rs12980275 and rs8099917) genes were studied to examine their associations with responses to IFN treatment in paediatric patients. We adopted two criteria for the therapeutic response, achieving an hepatitis B virus(HBV) DNA level < 2000 IU/m L and normalization of ALT activity(< 40 IU/L). To perform the analyses, we compared the patients in terms of achieving a partial response(PR) and a complete response(CR) upon measurement at the 24-wk posttreatment follow-up. RESULTS The PR and CR rates were 80.8% and 42.3%, respectively. Factors such as age, gender and liver histology had no impact on the type of response(partial or complete). A statistically significant relationship between higher baseline HBV DNA and ALT activity levels and lower rates of PR and CR was shown(P < 0.05). The allele association analysis revealed that only the IL-28 B rs12979860(C vs T) and IL28 B rs12980275(A vs G) markers significantly affected the achievement of PR(P = 0.021, OR = 3.3, 95%CI: 1.2-9.2 and P = 0.014, OR = 3.7, 95%CI: 1.3-10.1, respectively). However, in the genotype analysis, only IL-28 B rs12980275 was significantly associated with PR(AA vs AG-GG, P = 0.014, OR = 10.9, 95%CI: 1.3-93.9). The association analysis for CR showed that the TT genotype of IL28 B rs12979860 was present only in the no-CR group(P = 0.033) and the AA genotype of OASL rs10849829 was significantly more frequent in the noCR group(P = 0.044, OR = 0.26, 95%CI: 0.07-0.88). The haplotype analysis revealed significant associations between PR and CR and OAS haplotype(P = 0.0002 and P = 0.001, respectively), but no association with IL28 B haplotype was observed.CONCLUSION IL28 B and OAS polymorphisms are associated with different clinical outcomes in CHB children treated with interferon.
文摘In October 2015, an ISIS member speaking fluent Hebrew warned that soon there would be no Jews left in Jerusalem or in the rest of the land called "Israel". The Islamic State in Iraq and Syria (ISIS) will fulfill this mission according this Salafi-Jihadism group. ISIS ideology holds that it is first necessary to fight against the near enemy (the Arab states) but the last apocalyptic battle will be with the Jews (the far enemy). The purpose of this article is to reveal and present the development of Jew-hatred fi'om al-Qa'ida and up to the present doctrine oflSIS.
文摘This article presents a case study of the Siam Commercial Bank (SCB) by investigating why and how SCB implemented organizational restructuring during the uncertain economic environment, and gives an overview of the Thai commercial bank industry. This article presents and discusses SCB's strategy implementation in its organization during 1997-2010. This case study is aimed to provide some guidelines for other companies in developing and in choosing strategies for their business sustainability in the global change, and in choosing the implementation of their organization structure for competitive markets.
文摘Until the late 1980s, gastroenterology (GE) was considered a subspecialty of Internal Medicine. Today, GE also incorporates Hepatology. However, Digestive Oncology training is poorly defined in the Hepatogastroenterology (HGE)-curriculum. Therefore, a Digestive Oncology curriculum should be developed and this document might be a starting point for such a curriculum. HGE-specialists are increasingly resisting the paradigm in which they play only a diagnostic and technical role in the management of digestive tumors. We suggest minimum endpoints in the standard HGE-curriculum for oncology, and recommend a focus year in the Netherlands for Digestive Oncology in the HGE-curriculum. To produce welltrained digestive oncologists, an advanced Digestive Oncology training program with specific qualifications in Digestive Oncology (2 years) has been developed. The schedule in Belgium includes a period of at least 6 mo to be spent in a medical oncology department. The goal ofthese programs remains the production of well-trained digestive oncologists. HGE specialists are part of the multidisciplinary oncological teams, and some have been administering chemotherapy in their countries for years. In this article, we provide a road map for the organization of a proper training in Digestive Oncology. We hope that the World Gastroenterology Organisation and other (inter)national societies will support the necessary certifications for this specific training in the HGE-curriculum.
文摘On November 1973, about one month after the cease-fire at the end of the Yom Kippur War, the Arab League decided that the Palestine Liberation Organization (PLO) was the sole representative of the Palestinian people. This article examines the contribution of the PLO to the war effort of the Arab countries during the Yom Kippur War, the influence of the war upon the Palestinian problem, the Palestinian military contribution to the Arab war effort, Jordan's non-participation in the Yom Kippur War and the Egyptian attempt to include the PLO as the representative of the Palestinian people in future negotiations with Israel and the U.S. which enabled the PLO recognition as the Palestinians sole representative for 30 years.
文摘Sustainable construction, together with sustainability, is a growing concern in developed countries in order to influence construction organizations to make "achieving sustainability" in their projects a stringent prior objective. North Cyprus is a rapidly developing country with an annual economic growth of 7%. Construction became the leading sector within the economy after the boom in demand for holiday and retirement houses especially from English and German holidaymakers. Due to lack of government policy on sustainability, developers usually use traditional ways of construction, and the lack of an established link with international construction, which would help local developers be aware of the latest technology and sustainable building techniques, is the main challenges for North Cyprus construction sector to develop sustainable construction practices.
文摘Any enterprise now is a significant part of the world economy both in terms of trade and employment. The performance of a business organisation is in part dependent on the capability of its human resource (HR). The knowledge and experience of employees is a source of competitive advantage, however, whether this is realised or not may depend on having the right HR policies. Managers therefore seek to implement best practice, and in multinationals there is the potential for intra-organizational learning across national boundaries. The human being is the most important element in the development process and its ultimate goal. Attention to the management of human affairs and the effort to make man an effective contributing member in the development plans within organizations, is the responsibility of those working in the field of human resources management (HRM) which has become a distinguished field of management worldwide and plays an important role especially in the developing countries. This study discussed personnel management to HRM and how HRM functions.
文摘A weather station is proposed especially designed for developing countries, and to meet the standards of the international scientific community making research on the earth system. The station would measure in situ several ECV (essential climate variables). These data may enable an agricultural breakthrough in countries lacking meteorological infrastructure, help in climate change monitoring, and facilitate diffusion of wind energy. A pre-feasibility analysis is presented. It appears interesting that the station is supplied by a social enterprise. A research to establish the best shelter design using computational fluid dynamics is also reported. The criterion is the accuracy with which the surface air temperature is reproduced inside the shelter. A design following recommendations by the WMO (World Meteorological Organization), a smaller design with identical geometry, and two alternative small designs are analyzed. All four designs are simulated in PVC, natural rubber and wood, with and without white paint coating. The smaller shelters perform better. The influence of the material, dimensions and design is smaller than that of the white paint. Shelters made of PVC or rubber, and/or in alternative designs, may be more interesting if other criteria are considered, like whether logistics, manufacturing, etc. are more sustainable, easier and/or cheaper.
文摘The study reflects on previous World Bank and FAO reports that made the general recommendation to set both research and extension investment targets in developing countries at 1% of agricultural gross domestic product (AgGDP). In order to define proxies for country-specific extension investment targets, authors developed an extension investment model (EIM) based on socio-economic macro-indicators (poverty, undernourishment, access to information and population density) and a method to define estimates for cost increases related to climate change. These parameters helped estimating the demand for agricultural extension and investments required for it. Results showed that about half of the 94 developing and emerging countries should spend more than 1% of their respective share of GDP derived from agriculture and about a quarter of the countries, mostly in Africa and South East Asia, need to spend more than 2% of their AgGDP. The paper reveals significant differences in average investment requirements in different regions and shows the additional extension costs related to climate change and other areas that currently lack investment.
文摘The article surveys the development of the environmental movement in Israel from the establishment of the state through the present day. Based on trends and transformations in the institutional planning system, it appears that activism by environmental movement organizations in Israel can be divided into three sub-periods: the establishment period, marked by the Sharon Plan, the founding of the Society for the Protection of Nature in Israel and MALRAZ--Council for the Prevention of Noise and Air Pollution in Israel, and the enactment of the Kanovitch Law and the National Parks and Nature Reserves Law (1963). The next phase of institutionalization is characterized by the establishment of designated institutional bodies--the Nature Reserves Authority, the National Parks Authority and the Environmental Protection Service, and their integration into the national planning system. The institutionalization period concludes with the establishment of the Ministry of the Environment (1989) and the transition to the third period, sustainability. Prominent during this period is a trend toward multidimensional proactive environmental planning and policymaking, reaching across many areas and including extensive regulation As far as environmental organizations are concerned, these three periods comprised a framework of cultural action in which they developed, acted and shaped environmental discourse and practice in Israel. Based on other studies, the article offers a model that illustrates the development of the environmental movement while emphasizing the interaction between individual actors, local organizing and national organizations. Finally, some characteristics and insights regarding activism by environmental organizations in Israel are suggested.
文摘Different positions of the member states of the World Trade Organization (WTO), especially the developed and developing countries and also the United States of America (USA), the European Union (EU), and Japan representatives, were observed during the Doha Round of trade negotiations under the WTO. The problems of agriculture protection in the developed countries, for example in the EU and USA and also in the developing countries, were becoming serious obstacles during the negotiations. Despite the undeniable benefits of the multilateral WTO forum for trade liberalization, the rapid increase of North-South bilateral and multilateral free trade areas (FTAs) begs a systematic explanation for why some forums are prioritized relative to others. The main aim of the article is the presentation of some new aspects of the international business theory in the context of international economy. The article presents the mercantilist tendencies in the international trade policy, the theory of public choice in the foreign trade policy, protectionist pressures in different political systems, the level of protectionist pressures, food producers' pressure, and conflicts between the tendencies to sustainable international trade liberalization and environmental protection.
文摘The issue of the future of Europe is becoming increasingly important what with the depth of the economic crisis that started in 2008. In addition to a continuous growth in the number of the unemployed, the crisis particularly emphasizes the chronic level of energy dependence. The energy saving measures ~energy efficiency), diversification of sources (stability of supply), and the creation of substitutes in renewable energy (energy transition), intertwine with administrative measures and form the response of European countries to the growing energy dependence. At the same time, although facing the threatening warming (or cooling) of the Earth, Europe, as a big advocate of reducing CO2 remains passively dependent on NATO (North Atlantic Treaty Organization) policy in the field of defense in the context of energy dependence. However, for the first time after many decades, Europe and America do not have the same energy, and consequently geo-strategic objective: The US has become energy independent while Europe is chronically energy dependent.
文摘In 2018,the Chinese government identified four municipalities and seven sub-provincial cities for the implementation of the National Drug Pooled Procurement(NDPP)pilot program(the“4+7”policy).In the present study,we analyzed the effects of the“4+7”policy with data of 25 pilot drugs from the National Healthcare Security Administration(NHSA)from the aspects of drug price,volume,and expenditure.After the implementation of the policy,the average price of total and winning drugs was decreased by 54.47%and 73.82%,respectively,while the DDDc of non-winning drugs was decreased by only 1.54%,and the DDDc of uncertificated generic drugs was increased 83.18%.The DDDs indicating the volume of total and winning drugs was increased by 21.18%and 353.98%,respectively,and the DDDs of non-winning drugs was decreased by 61.35%.The costs of total and non-winning drugs were decreased by 44.83%and 61.94%,respectively,and the cost of winning drugs was increased by 18.87%.The“4+7”policy reduced the price and cost of pilot drugs and improved the affordability and accessibility of drugs.However,there were also problems with unexpected excessive price increases of uncertificated generic drugs and relatively high prices of non-winning products.Therefore,we highly suggested promoting the normalization and institutionalization of pooled drug procurement,enhancing the administrative capacity of local procurement platforms,and strengthening monitoring the price of non-winning,especially for the uncertificated generic drugs.
基金Supported by a Grant of Key Technology Standard Promotion Project(No.2006BAK04A20)from the Ministry of Science and Technology of Chinaa Grant(No.2009B26)from the World Federation of Acupuncture and Moxibustion Societies
文摘OBJECTIVE: To supply literature for developing an international standard of auricular acupuncture points. METHODS: Electronic database searches were con- ducted in the Chinese National Knowledge Infra- structure and VlP, and the Western databases, Pubmed, the National Science and Technology Li- brary, and the German Journal of Acupuncture, from 1990 to April, 2012. We also searched the doc- uments of international symposiums for auricular acupuncture points (AAPs). Keywords were "auricu- lar points", "auricular acupuncture points", "ear points", or "auriculotherapy" RESULTS: Basic and clinical research on AAPs was performed in China, the United States, France, andGermany. Clinical AAP research was done in Italy, Austria, Switzerland, Spain, the UK, Holland, Japan, Russia, and Africa. However, AAP research was not communicated internationally. The World Federa- tion of Acupuncture-Moxibustion Societies recom- mended international standard of auricular acu- puncture points (ISAAPs). Standardized nomencla- ture and locations of AAPs would provide a solid basis to draft an international standard organiza- tion. CONCLUSION: Experts need to find common points from different countries or regions, provide evidence of different ideas, and list the proposal as a recommendation for an international standard.