Background: The world of cancer care is an emotional place, given the severity of the disease being treated, the heavy workload, the suffering of patients, and the high number of deaths. The nursing staff who work the...Background: The world of cancer care is an emotional place, given the severity of the disease being treated, the heavy workload, the suffering of patients, and the high number of deaths. The nursing staff who work there may be exposed to constant stress from these factors. This study aimed to explore the psychological experience of the nursing staff of the Medical Oncology Department of the Yaoundé General Hospital. Methods: We carried out a cross-sectional study, in June 2017, involving the nursing staff of the Medical Oncology Department of the Yaoundé General Hospital. Results: Sixteen out of 18 nurses were interviewed. All had worked in at least one other department prior to Oncology. The number of years of experience in Oncology ranged from less than one year to 13 years. The choice of the Oncology department was involuntary for 100% of the staff;of these, 62% had intentions of changing departments. Twenty-five percent had applied for a change of department, which was unsuccessful. Stress was expressed by 94% of the staff;93% thought that there was a solution to the stress experienced on a daily basis in the Oncology department. The main solutions proposed to manage this stress were: support for the staff, provision of work materials, and staff training. Conclusion: The nursing staff of the Medical Oncology Department of the Yaoundé General Hospital experiences a high level of stress and are in need of solutions.展开更多
目的:本研究建立了一种一步净化法结合液相色谱串联质谱(LC-MS/MS)同时检测雅鱼(Schizothorax prenanti)中13类54种兽药残留的快速检测方法。方法:向2.0 g样品中加入8 mL 0.2%甲酸-乙腈:水溶液(90:10,V/V)提取,冰水浴超声提取,LPAS一步...目的:本研究建立了一种一步净化法结合液相色谱串联质谱(LC-MS/MS)同时检测雅鱼(Schizothorax prenanti)中13类54种兽药残留的快速检测方法。方法:向2.0 g样品中加入8 mL 0.2%甲酸-乙腈:水溶液(90:10,V/V)提取,冰水浴超声提取,LPAS一步净化。采用C18柱,甲醇-0.1%甲酸/5 mmol/L乙酸铵溶液梯度洗脱,动态多反应监测(dMRM),正/负离子模式,内标法定量,LC-MS/MS测定。以添加54种兽药的方式,对提取方式、提取体积、盐的加入、液相和质谱条件进行了优化,对方法性能(基质效应、方法检出限、方法定量限、准确度、精密度)等进行了验证。结果:54种兽药在0.1~50μg/L范围内线性关系良好,决定系数(R^(2))≥0.992,方法检出限(LOD)为0.03~2.5μg/kg之间,方法定量限(LOQ)为0.1~8.3μg/kg之间,在低(添加量5~10μg/kg)、中(添加量10~20μg/kg)、高(添加量50μg/kg)三个水平下54种药物的平均回收率为70.45%~118.1%,RSD为0.01%~9.9%。对50份养殖雅鱼样本应用该方法进行检测,7份样品有药物检出,恩诺沙星和达氟沙星各检出2次,磺胺甲噁唑检出4次,均低于定量限的定性检出。结论:该方法操作简单,一步净化,且方法检出限低、灵敏度高,准确度和精密度均较好,方法性能验证其符合多种兽药残留要求,可为大批量检测雅鱼中多种类兽药残留提供有力支持。展开更多
文摘Background: The world of cancer care is an emotional place, given the severity of the disease being treated, the heavy workload, the suffering of patients, and the high number of deaths. The nursing staff who work there may be exposed to constant stress from these factors. This study aimed to explore the psychological experience of the nursing staff of the Medical Oncology Department of the Yaoundé General Hospital. Methods: We carried out a cross-sectional study, in June 2017, involving the nursing staff of the Medical Oncology Department of the Yaoundé General Hospital. Results: Sixteen out of 18 nurses were interviewed. All had worked in at least one other department prior to Oncology. The number of years of experience in Oncology ranged from less than one year to 13 years. The choice of the Oncology department was involuntary for 100% of the staff;of these, 62% had intentions of changing departments. Twenty-five percent had applied for a change of department, which was unsuccessful. Stress was expressed by 94% of the staff;93% thought that there was a solution to the stress experienced on a daily basis in the Oncology department. The main solutions proposed to manage this stress were: support for the staff, provision of work materials, and staff training. Conclusion: The nursing staff of the Medical Oncology Department of the Yaoundé General Hospital experiences a high level of stress and are in need of solutions.
