The inference of genome ancestry and the estimation of molecular relatedness are of great importance for breeding efficiency and association studies. Seventy SSR loci, evenly distributed in 10 chromosomes, were assaye...The inference of genome ancestry and the estimation of molecular relatedness are of great importance for breeding efficiency and association studies. Seventy SSR loci, evenly distributed in 10 chromosomes, were assayed for polymorphism among 187 commonly used maize (Zea mays L.) inbreds which represent the genetic diversity in China. The identified 290 alleles served as raw data for estimating population structure using the coalescent linked loci, based on the ADMIXTURE model. Population number, K, has been inferred to be between five and seven. Specifying five subpopulations (K = 5) led to a distinct decrease and specifying K to be greater than six resulted in only minimal increases in the likelihood value. Therefore, population number, K, has been inferred into six subpopulations, which are PA, BSSS (includes Reid), PB, Lan (Lancaster Sure Crop), LRC (Luda Reb Cob, a Chinese landrace, and its derivatives), and SPT (Si-ping-tou, a Chinese landrace and its derivatives). The Kullback-Leibler distance of pairwise subpopulation was also inferred as n × p (187 ×6) Q matrices, which gave a detailed percentage of genetic composition of six subpopulations and molecular relatedness of each line. The genome-wide linkage disequilibrium (LD) indicated that the asso- ciation studies in QTLs and/or candidate genes might avoid nonfunctional and spurious associations, as most of the LD blocks were broken among diverse germplasm. The defined population structure has given us a clear genetic structure of these lines for breeding practice and established a good basis for association analysis.展开更多
In the discipline of geotechnical engineering, fiber optic sensor based distributed monitoring has played an increasingly important role over the past few decades. Compared with conventional sensors, fiber optic senso...In the discipline of geotechnical engineering, fiber optic sensor based distributed monitoring has played an increasingly important role over the past few decades. Compared with conventional sensors, fiber optic sensors have a variety of exclusive advantages, such as smaller size, higher precision, and better corrosion resistance. These innovative monitoring technologies have been successfully applied for performance monitoring of geo-structures and early warning of potential geo- hazards around the world. In order to investigate their ability to monitor slope stability problems, a medium-sized model of soil nailed slope has been constructed in laboratory. The fully distributed Brillouin optical time-domain analysis (BOTDA) sensing technology was employed to measure the horizontal strain distributions inside the model slope. During model construction, a specially designed strain sensing fiber was buried in the soil mass. Afterward, the surcharge loading was applied on the slope crest in stages using hydraulic jacks and a reaction frame. During testing, an NBX-6o5o BOTDA sensing interrogator was used to collect the fiber optic sensing data. The test results have been analyzed in detail, which shows that the fiber optic sensors can capture the progressive deformation and failure pattern of the model slope. The limit equilibrium analyses were also conducted to obtain the factors ofsafety of the slope under different surface loadings. It is found that the characteristic maximum strains can reflect the stability of the model slope and an empirical relationship was obtained, This study verified the effectiveness of the distributed BOTDA sensing technology in performance monitoring of slope.展开更多
Hoek–Brown(HB)strength criterion can reflect rock’s inherent failure nature,so it is more suitable for analyzing the stability of rock slopes.However,the traditional limit equilibrium methods are at present only sui...Hoek–Brown(HB)strength criterion can reflect rock’s inherent failure nature,so it is more suitable for analyzing the stability of rock slopes.However,the traditional limit equilibrium methods are at present only suitable for analyzing the rock slope stability using the linear equivalent Mohr–Coulomb(EMC)strength parameters instead of the nonlinear HB strength criterion.Therefore,a new method derived to analyze directly the rock slope stability using the nonlinear HB strength criterion for arbitrary curve slip surface was described in the limit equilibrium framework.The current method was established based on certain assumptions concerning the stresses on the slip surface through amending the initial normal stressσ0 obtained without considering the effect of inter-slice forces,and it can satisfy all static equilibrium conditions of the sliding body,so the current method can obtain the reasonable and strict factor of safety(FOS)solutions.Compared with the results of other methods in some examples,the feasibility of the current method was verified.Meanwhile,the parametric analysis shows that the slope angleβhas an important influence on the difference of the results obtained using the nonlinear HB strength criterion and its linear EMC strength parameters.Forβ≤45°,both of the results are similar,showing the traditional limit equilibrium methods using the linear EMC strength parameters and the current method are all suitable to analyze rock slope stability,but forβ>60°,the differences of both the results are obvious,showing the actual slope stability state can not be reflected in the traditional limit equilibrium methods,and then the current method should be used.展开更多
In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values w...In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large numberof samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data,we developed a robust and user-friendly software platform with a series of tools for analysis in association study withhigh efficiency. The platform has been well evaluated by several sets of real data.展开更多
Using a combination of close-range photogrammetry and three-dimensional(3-D) limit equilibrium theory, a determination method for the shear strength parameters of rock-soil mixture is presented. A close-range photogra...Using a combination of close-range photogrammetry and three-dimensional(3-D) limit equilibrium theory, a determination method for the shear strength parameters of rock-soil mixture is presented. A close-range photogrammetry method is used for measurement of the 3-D terrain of the experimental target. Auto CAD Lisp and EXCEL VBA are used to perform 3-D limit equilibrium analysis of the stability of sliding mass and perform backanalysis of shear strength parameters. The presented method was used to determine the shear strength parameters of rock-soil mixtures at the Liyuan Hydropower Station. The 3-D terrain of sliding surface could be measured notably well using of closerange photogrammetry. The computed results reveal that the cohesion and friction angle of rock-soil mixtures were 3.15 k Pa and 29.88o for test A, respectively, and 4.43 k Pa and 28.30o for test B, respectively, within the range of shear strength parameters, as determined by field and laboratory tests. The computation of shear strength parameters is influenced by the mesh grid number, especially the cohesion of the rock-soil mixture. The application of close-range photogrammetry can reduce the siteworks and improve the computational efficiency and accuracy.展开更多
Backfill is increasingly used in underground mines to reduce the surface impact from the wastes produced by the mining operations. But the main objectives of backfilling are to improve ground stability and reduce ore ...Backfill is increasingly used in underground mines to reduce the surface impact from the wastes produced by the mining operations. But the main objectives of backfilling are to improve ground stability and reduce ore dilution. To this end, the backfill in a stope must possess a minimum strength to remain self-standing during mining of an adjacent stope. This required strength is often estimated using a solution proposed by Mitchell and co-workers, which was based on a limit equilibrium analysis of a wedge exposed by the open face. In this paper, three dimensional numerical simulations have been performed to assess the behavior of the wedge model. A new limit equilibrium solution is proposed, based on the backfill displacements obtained from the simulations. Comparisons are made between the proposed solution and experimental and numerical modeling results. Compared with the previous solution, a better agreement is obtained between the new solution and experimental results for the required cohesion and factor of safety. For large scale(field) conditions, the results also show that the required strength obtained from the proposed solution corresponds quite well to the simulated backfill response.展开更多
Traditional rigid body limit equilibrium method (RBLEM) was adopted for the stability evaluation and analysis of rock slope under earthquake scenario. It is not able to provide the real stress distribution of the st...Traditional rigid body limit equilibrium method (RBLEM) was adopted for the stability evaluation and analysis of rock slope under earthquake scenario. It is not able to provide the real stress distribution of the structure, while the strength reduction method relies on the arbitrary decision on the failure criteria. The dynamic limit equilibrium solution was proposed for the stability analysis of sliding block based on 3-D multi-grid method, by incorporating implicit stepping integration FEM. There are two independent meshes created in the analysis: One original 3-D FEM mesh is for the simulation of target structure and provides the stress time-history, while the other surface grid is for the simulation of sliding surface and could be selected and designed freely. As long as the stress time-history of the geotechnical structure under earthquake scenario is obtained based on 3-D nonlinear dynamic FEM analysis, the time-history of the force on sliding surface could be derived by projecting the stress time-history from 3-D FEM mesh to surface grid. After that, the safety factor time-history of the sliding block will be determined through applying limit equilibrium method. With those information in place, the structure's aseismatic stability ean be further studied. The above theory and method were also applied to the aseismatic stability analysis of Dagangshan arch dam's right bank high slope and compared with the the result generated by Quasi-static method. The comparative analysis reveals that the method not only raises the FEM's capability in accurate simulation of complicated geologic structure, but also increases the flexibility and comprehensiveness of limit equilibrium method. This method is reliable and recommended for further application in other real geotechnical engineering.展开更多
Masu salmon,Oncorhynchus masou masou,is one of the most valuable fishery species that has been introduced to China,though to date no studies on the genetic diversity and genetic relationship among hatchery populations...Masu salmon,Oncorhynchus masou masou,is one of the most valuable fishery species that has been introduced to China,though to date no studies on the genetic diversity and genetic relationship among hatchery populations has been performed with molecular markers.We undertook such a study and sampled 120 individuals from three hatchery stocks and analyzed 20 microsatellite loci.All loci were polymorphic and a total of 91 alleles were detected.A relatively low level of genetic diversity was revealed with effective number of allele of 3.1094,3.3299 and 3.1894 and expected heterozygosity of 0.6600,0.6648 and 0.6638 in the three stocks,respectively.Deviations from Hardy-Weinberg equilibrium were found due to heterozygote deficit.Accordingly,evidence of genetic bottlenecks were found in the three stocks.An individual assignment test demonstrated that 85% of individuals were correctly assigned into their original stocks.Pairwise Fst revealed that significant differentiation occurred between these three stocks.The results of the study indicated that disequilibrium of genetic structure and differentiation has occurred in all three stocks.This information collectively provides a basis for measures to avoid of loss of genetic diversity and introgression in Chinese aquaculture.展开更多
Based on the principle of energy conservation,the applicable technique for drained cell retrofitted from conventional one was analyzed with 2D finite element model. The model employed a 1D heat transfer scheme to comp...Based on the principle of energy conservation,the applicable technique for drained cell retrofitted from conventional one was analyzed with 2D finite element model. The model employed a 1D heat transfer scheme to compute iteratively the freeze profile until the thickness variable reached the terminating requirement. The calculated 2D heat dissipation from the cell surfaces was converted into the overall 3D heat loss. The potential drop of the system, freeze profile and heat balance were analyzed to evaluate their variation with technical parameters when designing the 150 kA conventional cell based drained cell. The simulation results show that the retrofitted drained cell is able to keep thermal balance under the conditions that the current is 190 kA, the anodic current density is 0.96 A/cm2, the anode-cathode distance is 2.5 cm, the alumina cover is 16 cm thick with a thermal conductivity of 0.20 W/(m·℃ ) and the electrolysis temperature is 946 ℃ .展开更多
A slope will slide if the unbalanced force does not tend to zero when the stability of the slope is analyzed with the help of FLAC. Thus the ultimate reason of slope sliding is the unbalanced force determined by FLAC....A slope will slide if the unbalanced force does not tend to zero when the stability of the slope is analyzed with the help of FLAC. Thus the ultimate reason of slope sliding is the unbalanced force determined by FLAC. The slope will remain stable if the unbalanced force is counterbalanced by a reinforcement force which is produced by a suitable reinforcement method. In this paper, the stability of the slope was analyzed by using FLAC, and the unbalanced force of the slope was obtained through the FISH function in FLAC. According to the equilibrium conditions, the relationship between the reinforcement force and unbalanced force was derived and accordingly the reinforcement force was determined. The reinforcement design was adopted by using pre-stressed anchor bars on the basis of the reinforcement force. An example is used to show that the effect of slope reinforcement based on the reinforcement force is safe and economical. The method doesn't need to suppose a sliding surface to obtain the reinforcement force, and it is also clear in physical meaning. So this method realized the organic unification of the stability analysis and the slope reinforcement.展开更多
The article analyses the temporal spatial changes of profiles by EOF (Empirical Orthogonal Function) analysis and DTM analysis of GIS. These profiles, which are not affected by engineering, are chosen from the coast w...The article analyses the temporal spatial changes of profiles by EOF (Empirical Orthogonal Function) analysis and DTM analysis of GIS. These profiles, which are not affected by engineering, are chosen from the coast with successive field monitoring data from 1990 to 1999. Temporal and spatial EOF indicates the obvious stability of coast profile parameters in Fengxian tidal flat. In spatial scale, high tidal flats and deep water terraces are in a balance state while upper clino with steep slopes are sensitive and the stability is easy to be destroyed. In temporal scale, the erosion and deposition in this area are kept in balance in a whole. There are almost no change below 8- 9.5m. At the same time, it is the lower limit of tidal affection and the erosion and deposition process from it to high tidal flat keep in balance for many years. So the closure depth is appointed to from 8m to 9.5 m (Wusong datum mark).展开更多
Solubility of benzoic acid, terephthalic acid and 2,6-naphthalene dicarboxylic acid in water, acetic acid, N.N-dimethylformamide, N.N-dimethylacetamide, dimethyl sulphoxide and Ar-methyl-2-ketopyrrolidine were measure...Solubility of benzoic acid, terephthalic acid and 2,6-naphthalene dicarboxylic acid in water, acetic acid, N.N-dimethylformamide, N.N-dimethylacetamide, dimethyl sulphoxide and Ar-methyl-2-ketopyrrolidine were measured by dynamic method. The solubilities were calculated by UNIFAC group contribution method, in which new groups, BCCOOH and NCCOOH, were introduced to express the activity coefficients of aromatic acids and new interaction parameters of the new groups were expressed as the function of temperature, which were determined from the experimental data. The new interaction parameters provided good calculated result. The experimental data were also correlated with Wilson and y-h models, and results were compared with present UNIFAC model.展开更多
To investigate the seismic passive earth thrust with two-dimensional steady seepage, a general pseudo-dynamic solution was established based on the limit equilibrium analysis. This solution was purposefully applied to...To investigate the seismic passive earth thrust with two-dimensional steady seepage, a general pseudo-dynamic solution was established based on the limit equilibrium analysis. This solution was purposefully applied to a waterfront gravity wall, which retains a submerged backfill with a drainage system along the backfill-structure interface. The wall was assumed to move towards the backfill to the passive failure state. And the theoretical derivation considered the pore pressures induced by the seepage, the excess pore pressures generated by the earthquake and the seismic inertial forces. Thereinto, the hydrostatic and hydrodynamic pressures were calculated by the analytical formulas, while the seismic forces were obtained by the pseudo-dynamic method. In the parametric study, the results indicate that the velocity of shear wave has a more prominent impact on the seismic passive earth thrust than that of primary wave. Both the horizontal and vertical seismic actions decrease the passive earth pressure, but the horizontal one affects the amplitude of the earth pressure coefficient more significantly. Moreover, the soil friction and the wall friction distinctly increase the seismic passive earth pressure just like the static situation. The comparison shows that the results are consistent with the previous work, which verifies its validity.展开更多
To reduce the complexity of the configuration and control strategy for shoulder rehabilitation exoskeleton,a 2R1R1P2R serial of shoulder exoskeleton based on gravity balance is proposed.Based on three basic rotatory s...To reduce the complexity of the configuration and control strategy for shoulder rehabilitation exoskeleton,a 2R1R1P2R serial of shoulder exoskeleton based on gravity balance is proposed.Based on three basic rotatory shoulder joints,an exact kinematic constraint system can be formed between the exoskeleton and the upper arm by introducing a passive sliding pair and a center of glenohumeral(CGH)unpowered compensation mechanism,which realizes the human-machine kinematic compatibility.Gravity balance is used in the CGH compensation mechanism to provide shoulder joint support.Meanwhile,the motion of the compensation mechanism is pulled by doing reverse leading through the arm to realize the kinematic self-adaptive,which decreases control complexity.Besides,a simple and intuitive spring adjustment strategy is proposed to ensure the gravity balance of any prescribed quality.Furthermore,according to the influencing factors analysis of the scapulohumeral rhythm,the kinematic analysis of CGH mechanism is performed,which shows that the mechanism can fit the trajectory of CGH under various conditions.Finally,the dynamic simulation of the mechanism is carried out.Results indicate that the compensation torques are reduced to below 0.22 N·m,and the feasibility of the mechanism is also verified.展开更多
This paper describes a precise method combining numerical analysis and limit equilibrium theory to determine potential slip surfaces in soil slopes. In this method, the direction of the critical slip surface at any po...This paper describes a precise method combining numerical analysis and limit equilibrium theory to determine potential slip surfaces in soil slopes. In this method, the direction of the critical slip surface at any point in a slope is determined using the Coulomb’s strength principle and the extremum principle based on the ratio of the shear strength to the shear stress at that point. The ratio, which is considered as an analysis index, can be computed once the stress field of the soil slope is obtained. The critical slip direction at any point in the slope must be the tangential direction of a potential slip surface passing through the point. Therefore, starting from a point on the top of the slope surface or on the horizontal segment outside the slope toe, the increment with a small distance into the slope is used to choose another point and the corresponding slip direction at the point is computed. Connecting all the points used in the computation forms a potential slip surface exiting at the starting point. Then the factor of safety for any potential slip surface can be computed using limit equilibrium method like Spencer method. After factors of safety for all the potential slip surfaces are obtained, the minimum one is the factor of safety for the slope and the corresponding potential slip surface is the critical slip surface of the slope. The proposed method does not need to pre-assume the shape of potential slip surfaces. Thus it is suitable for any shape of slip surfaces. Moreover the method is very simple to be applied. Examples are presented in this paper to illustrate the feasibility of the proposed method programmed in ANSYS software by macro commands.展开更多
In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamb...In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamber was conducted. Based on mathematical description of optimal arrangement for pressure measurement points,fuzzy clustering analysis and discriminant analysis were used to divide pressure regions of nodes on bulkhead. Finally,the selection method of optimal measurement points was proposed,and by selecting d6.28 m EPBS as study object,the case study was conducted. By contrast,based on optimal arrangement scheme of pressure measurement points,through adopting weighted algorithm,the absolute error mean of equivalent pressure of working chamber is the smallest. In addition,pressure curve of optimal arrangement points presents parabola,and it can show the state of pressure distribution on bulkhead truly. It is concluded that the optimal arrangement method of pressure measurement points in working chamber is effective and feasible,and the method can provide basis for realizing high precision pressure control of EPBS.展开更多
Two calculation modes for the effect of external load on slope stability, i.e., mode I in which the external load is thought to act on slope surface, and mode II in which the external load is thought to act on slip su...Two calculation modes for the effect of external load on slope stability, i.e., mode I in which the external load is thought to act on slope surface, and mode II in which the external load is thought to act on slip surface along the force action line, were considered. Meanwhile, four basic distribution patterns of external load were used, of which complex external loads could be composed. In analysis process, several limit equilibrium methods, such as Swedish method, simplified Bishop method, simplified Janbu method, Spencer method, Morgenstern-Price(M-P) method, Sarma method, and unbalanced thrust method, were also adopted to contrast their differences in slope stability under the external load. According to parametric analysis, some conclusions can be obtained as follows:(1) The external load, with the large magnitude, small inclination angle, and acting position close to the slope toe,has more positive effect on slope stability;(2) The results calculated using modes I and II of external load are similar, indicating that the calculation mode of external load has little influence on slope stability;(3) If different patterns of external loads are equivalent to each other, their slope stability under these external loads are the same, and if not, the external load leads to the better slope stability,as action position of the resultant force for external load is closer to the lower sliding point of slip surface.展开更多
The selective precipitation of zinc from zinc-nickel sulfate solution with the Zn/Ni molar ratio of20:1was studied.Dropwise addition of0.5mol/L NaOH solution into the zinc-nickel sulfate solution containing0,0.01,0.02...The selective precipitation of zinc from zinc-nickel sulfate solution with the Zn/Ni molar ratio of20:1was studied.Dropwise addition of0.5mol/L NaOH solution into the zinc-nickel sulfate solution containing0,0.01,0.02,0.03and0.04mol/L ethylene diamine tetraacetate(EDTA)as a chelating agent was done.The equilibrium analysis of precipitation pathway was performed using Visual MINTEQ program.The equilibrium analysis showed that the presence of small amounts of EDTA can prevent nickel precipitation in alkaline conditions without any negative effect on zinc precipitation.On this basis,more than90%of zinc could be precipitated as a product with about50%Zn and only0.11%Ni at pH=9.0merely as a result of the presence of0.03mol/L EDTA in the solution.The stirring time of120min after precipitation was found to be essential for more complete separation.The X-ray diffraction studies on the precipitate revealed that the precipitated phase was Zn4(OH)6SO4.4H2O.展开更多
Toluene-2,4-bisurea (TBU) is an important intermediate for urea route to dimethyl toluene-2,4-dicarbamate and the study on TBU synthesis via the reaction of 2,4-toluene diamine (TDA) and urea is of great significance....Toluene-2,4-bisurea (TBU) is an important intermediate for urea route to dimethyl toluene-2,4-dicarbamate and the study on TBU synthesis via the reaction of 2,4-toluene diamine (TDA) and urea is of great significance. Firstly, thermodynamic analysis shows that the reaction is exothermic and a high equilibrium conversion of TDA is expected due to its large reaction equilibrium constant. Secondly, under the suitable reaction conditions, 130 °C, 7 h, and molar ratio of TDA/zinc acetate/urea/sulfolane 1/0.05/3.5/10, TDA conversion is 54.3%, and TBU yield and selectivity are 39.8% and 73.3% respectively. Lastly, the synthesis of TBU is a 1st order reaction with respect to TDA and the reaction kinetics model is established. This work will provide useful information for commercializing the urea route to toluene-2,4-dicarbamate (TDC).展开更多
文摘The inference of genome ancestry and the estimation of molecular relatedness are of great importance for breeding efficiency and association studies. Seventy SSR loci, evenly distributed in 10 chromosomes, were assayed for polymorphism among 187 commonly used maize (Zea mays L.) inbreds which represent the genetic diversity in China. The identified 290 alleles served as raw data for estimating population structure using the coalescent linked loci, based on the ADMIXTURE model. Population number, K, has been inferred to be between five and seven. Specifying five subpopulations (K = 5) led to a distinct decrease and specifying K to be greater than six resulted in only minimal increases in the likelihood value. Therefore, population number, K, has been inferred into six subpopulations, which are PA, BSSS (includes Reid), PB, Lan (Lancaster Sure Crop), LRC (Luda Reb Cob, a Chinese landrace, and its derivatives), and SPT (Si-ping-tou, a Chinese landrace and its derivatives). The Kullback-Leibler distance of pairwise subpopulation was also inferred as n × p (187 ×6) Q matrices, which gave a detailed percentage of genetic composition of six subpopulations and molecular relatedness of each line. The genome-wide linkage disequilibrium (LD) indicated that the asso- ciation studies in QTLs and/or candidate genes might avoid nonfunctional and spurious associations, as most of the LD blocks were broken among diverse germplasm. The defined population structure has given us a clear genetic structure of these lines for breeding practice and established a good basis for association analysis.
基金the financial support provided by the National Basic Research Program of China (973 Program) (Grant No. 2011CB710605)the National Natural Science Foundation of China (Grant Nos. 41102174, 41302217)supported by the National Key Technology R&D Program of China (Grant No. 2012BAK10B05)
文摘In the discipline of geotechnical engineering, fiber optic sensor based distributed monitoring has played an increasingly important role over the past few decades. Compared with conventional sensors, fiber optic sensors have a variety of exclusive advantages, such as smaller size, higher precision, and better corrosion resistance. These innovative monitoring technologies have been successfully applied for performance monitoring of geo-structures and early warning of potential geo- hazards around the world. In order to investigate their ability to monitor slope stability problems, a medium-sized model of soil nailed slope has been constructed in laboratory. The fully distributed Brillouin optical time-domain analysis (BOTDA) sensing technology was employed to measure the horizontal strain distributions inside the model slope. During model construction, a specially designed strain sensing fiber was buried in the soil mass. Afterward, the surcharge loading was applied on the slope crest in stages using hydraulic jacks and a reaction frame. During testing, an NBX-6o5o BOTDA sensing interrogator was used to collect the fiber optic sensing data. The test results have been analyzed in detail, which shows that the fiber optic sensors can capture the progressive deformation and failure pattern of the model slope. The limit equilibrium analyses were also conducted to obtain the factors ofsafety of the slope under different surface loadings. It is found that the characteristic maximum strains can reflect the stability of the model slope and an empirical relationship was obtained, This study verified the effectiveness of the distributed BOTDA sensing technology in performance monitoring of slope.
基金Project(2015M580702)supported by China Postdoctoral Science FoundationProject(51608541)supported by the National Natural Science Foundation of ChinaProject(2014122066)supported by the Guizhou Provincial Department of Transportation Foundation,China
文摘Hoek–Brown(HB)strength criterion can reflect rock’s inherent failure nature,so it is more suitable for analyzing the stability of rock slopes.However,the traditional limit equilibrium methods are at present only suitable for analyzing the rock slope stability using the linear equivalent Mohr–Coulomb(EMC)strength parameters instead of the nonlinear HB strength criterion.Therefore,a new method derived to analyze directly the rock slope stability using the nonlinear HB strength criterion for arbitrary curve slip surface was described in the limit equilibrium framework.The current method was established based on certain assumptions concerning the stresses on the slip surface through amending the initial normal stressσ0 obtained without considering the effect of inter-slice forces,and it can satisfy all static equilibrium conditions of the sliding body,so the current method can obtain the reasonable and strict factor of safety(FOS)solutions.Compared with the results of other methods in some examples,the feasibility of the current method was verified.Meanwhile,the parametric analysis shows that the slope angleβhas an important influence on the difference of the results obtained using the nonlinear HB strength criterion and its linear EMC strength parameters.Forβ≤45°,both of the results are similar,showing the traditional limit equilibrium methods using the linear EMC strength parameters and the current method are all suitable to analyze rock slope stability,but forβ>60°,the differences of both the results are obvious,showing the actual slope stability state can not be reflected in the traditional limit equilibrium methods,and then the current method should be used.
基金This work was supported by the Major State Basic Research Development program of Chinathe National High Technology Research and Development Program of China.
文摘In multiloci-based genetic association studies of complex diseases, a powerful and high efficient tool for analyses oflinkage disequilibrium (LD) between markers, haplotype distributions and many chi-square/p values with a large numberof samples has been sought for long. In order to achieve the goal of obtaining meaningful results directly from raw data,we developed a robust and user-friendly software platform with a series of tools for analysis in association study withhigh efficiency. The platform has been well evaluated by several sets of real data.
基金the support of the National Natural Science Foundation of China (Grant Nos. 41472272, 41102194)the Key Deployment Project of the Chinese Academy of Sciences (KZZD-EW-05-01)the Science Foundation for Excellent Youth Scholars of Sichuan University (2013SCU04A07)
文摘Using a combination of close-range photogrammetry and three-dimensional(3-D) limit equilibrium theory, a determination method for the shear strength parameters of rock-soil mixture is presented. A close-range photogrammetry method is used for measurement of the 3-D terrain of the experimental target. Auto CAD Lisp and EXCEL VBA are used to perform 3-D limit equilibrium analysis of the stability of sliding mass and perform backanalysis of shear strength parameters. The presented method was used to determine the shear strength parameters of rock-soil mixtures at the Liyuan Hydropower Station. The 3-D terrain of sliding surface could be measured notably well using of closerange photogrammetry. The computed results reveal that the cohesion and friction angle of rock-soil mixtures were 3.15 k Pa and 29.88o for test A, respectively, and 4.43 k Pa and 28.30o for test B, respectively, within the range of shear strength parameters, as determined by field and laboratory tests. The computation of shear strength parameters is influenced by the mesh grid number, especially the cohesion of the rock-soil mixture. The application of close-range photogrammetry can reduce the siteworks and improve the computational efficiency and accuracy.
基金financial support of the Natural Sciences and Engineering Research Council (NSERC) of Canada and the partners of Research Institute on Mines and the Environment (RIME UQAT-Polytechnique http://rime-irme.ca)
文摘Backfill is increasingly used in underground mines to reduce the surface impact from the wastes produced by the mining operations. But the main objectives of backfilling are to improve ground stability and reduce ore dilution. To this end, the backfill in a stope must possess a minimum strength to remain self-standing during mining of an adjacent stope. This required strength is often estimated using a solution proposed by Mitchell and co-workers, which was based on a limit equilibrium analysis of a wedge exposed by the open face. In this paper, three dimensional numerical simulations have been performed to assess the behavior of the wedge model. A new limit equilibrium solution is proposed, based on the backfill displacements obtained from the simulations. Comparisons are made between the proposed solution and experimental and numerical modeling results. Compared with the previous solution, a better agreement is obtained between the new solution and experimental results for the required cohesion and factor of safety. For large scale(field) conditions, the results also show that the required strength obtained from the proposed solution corresponds quite well to the simulated backfill response.
基金Project(2013-KY-2) supported by the State Key Laboratory of Hydroscience and Engineering of Hydroscience, ChinaProject(50925931)supported by the National Funds for Distinguished Young Scientists, China
文摘Traditional rigid body limit equilibrium method (RBLEM) was adopted for the stability evaluation and analysis of rock slope under earthquake scenario. It is not able to provide the real stress distribution of the structure, while the strength reduction method relies on the arbitrary decision on the failure criteria. The dynamic limit equilibrium solution was proposed for the stability analysis of sliding block based on 3-D multi-grid method, by incorporating implicit stepping integration FEM. There are two independent meshes created in the analysis: One original 3-D FEM mesh is for the simulation of target structure and provides the stress time-history, while the other surface grid is for the simulation of sliding surface and could be selected and designed freely. As long as the stress time-history of the geotechnical structure under earthquake scenario is obtained based on 3-D nonlinear dynamic FEM analysis, the time-history of the force on sliding surface could be derived by projecting the stress time-history from 3-D FEM mesh to surface grid. After that, the safety factor time-history of the sliding block will be determined through applying limit equilibrium method. With those information in place, the structure's aseismatic stability ean be further studied. The above theory and method were also applied to the aseismatic stability analysis of Dagangshan arch dam's right bank high slope and compared with the the result generated by Quasi-static method. The comparative analysis reveals that the method not only raises the FEM's capability in accurate simulation of complicated geologic structure, but also increases the flexibility and comprehensiveness of limit equilibrium method. This method is reliable and recommended for further application in other real geotechnical engineering.
基金HRFRI Basic Science Research Special Funds(2009HSYZX-YY-10)Heilongjiang Natural Science Fund (C201044)Heilongjiang Postdoctoral Sustentation Fund (LRB10-081)
文摘Masu salmon,Oncorhynchus masou masou,is one of the most valuable fishery species that has been introduced to China,though to date no studies on the genetic diversity and genetic relationship among hatchery populations has been performed with molecular markers.We undertook such a study and sampled 120 individuals from three hatchery stocks and analyzed 20 microsatellite loci.All loci were polymorphic and a total of 91 alleles were detected.A relatively low level of genetic diversity was revealed with effective number of allele of 3.1094,3.3299 and 3.1894 and expected heterozygosity of 0.6600,0.6648 and 0.6638 in the three stocks,respectively.Deviations from Hardy-Weinberg equilibrium were found due to heterozygote deficit.Accordingly,evidence of genetic bottlenecks were found in the three stocks.An individual assignment test demonstrated that 85% of individuals were correctly assigned into their original stocks.Pairwise Fst revealed that significant differentiation occurred between these three stocks.The results of the study indicated that disequilibrium of genetic structure and differentiation has occurred in all three stocks.This information collectively provides a basis for measures to avoid of loss of genetic diversity and introgression in Chinese aquaculture.
基金Projects(50374081 60634020) supported by the National Natural Science Foundation of China
文摘Based on the principle of energy conservation,the applicable technique for drained cell retrofitted from conventional one was analyzed with 2D finite element model. The model employed a 1D heat transfer scheme to compute iteratively the freeze profile until the thickness variable reached the terminating requirement. The calculated 2D heat dissipation from the cell surfaces was converted into the overall 3D heat loss. The potential drop of the system, freeze profile and heat balance were analyzed to evaluate their variation with technical parameters when designing the 150 kA conventional cell based drained cell. The simulation results show that the retrofitted drained cell is able to keep thermal balance under the conditions that the current is 190 kA, the anodic current density is 0.96 A/cm2, the anode-cathode distance is 2.5 cm, the alumina cover is 16 cm thick with a thermal conductivity of 0.20 W/(m·℃ ) and the electrolysis temperature is 946 ℃ .
基金Project 50492073 supported by National Natural Science Foundation of China
文摘A slope will slide if the unbalanced force does not tend to zero when the stability of the slope is analyzed with the help of FLAC. Thus the ultimate reason of slope sliding is the unbalanced force determined by FLAC. The slope will remain stable if the unbalanced force is counterbalanced by a reinforcement force which is produced by a suitable reinforcement method. In this paper, the stability of the slope was analyzed by using FLAC, and the unbalanced force of the slope was obtained through the FISH function in FLAC. According to the equilibrium conditions, the relationship between the reinforcement force and unbalanced force was derived and accordingly the reinforcement force was determined. The reinforcement design was adopted by using pre-stressed anchor bars on the basis of the reinforcement force. An example is used to show that the effect of slope reinforcement based on the reinforcement force is safe and economical. The method doesn't need to suppose a sliding surface to obtain the reinforcement force, and it is also clear in physical meaning. So this method realized the organic unification of the stability analysis and the slope reinforcement.
文摘The article analyses the temporal spatial changes of profiles by EOF (Empirical Orthogonal Function) analysis and DTM analysis of GIS. These profiles, which are not affected by engineering, are chosen from the coast with successive field monitoring data from 1990 to 1999. Temporal and spatial EOF indicates the obvious stability of coast profile parameters in Fengxian tidal flat. In spatial scale, high tidal flats and deep water terraces are in a balance state while upper clino with steep slopes are sensitive and the stability is easy to be destroyed. In temporal scale, the erosion and deposition in this area are kept in balance in a whole. There are almost no change below 8- 9.5m. At the same time, it is the lower limit of tidal affection and the erosion and deposition process from it to high tidal flat keep in balance for many years. So the closure depth is appointed to from 8m to 9.5 m (Wusong datum mark).
文摘Solubility of benzoic acid, terephthalic acid and 2,6-naphthalene dicarboxylic acid in water, acetic acid, N.N-dimethylformamide, N.N-dimethylacetamide, dimethyl sulphoxide and Ar-methyl-2-ketopyrrolidine were measured by dynamic method. The solubilities were calculated by UNIFAC group contribution method, in which new groups, BCCOOH and NCCOOH, were introduced to express the activity coefficients of aromatic acids and new interaction parameters of the new groups were expressed as the function of temperature, which were determined from the experimental data. The new interaction parameters provided good calculated result. The experimental data were also correlated with Wilson and y-h models, and results were compared with present UNIFAC model.
基金Projects(U1234204,51378463) supported by the National Natural Science Foundation of China
文摘To investigate the seismic passive earth thrust with two-dimensional steady seepage, a general pseudo-dynamic solution was established based on the limit equilibrium analysis. This solution was purposefully applied to a waterfront gravity wall, which retains a submerged backfill with a drainage system along the backfill-structure interface. The wall was assumed to move towards the backfill to the passive failure state. And the theoretical derivation considered the pore pressures induced by the seepage, the excess pore pressures generated by the earthquake and the seismic inertial forces. Thereinto, the hydrostatic and hydrodynamic pressures were calculated by the analytical formulas, while the seismic forces were obtained by the pseudo-dynamic method. In the parametric study, the results indicate that the velocity of shear wave has a more prominent impact on the seismic passive earth thrust than that of primary wave. Both the horizontal and vertical seismic actions decrease the passive earth pressure, but the horizontal one affects the amplitude of the earth pressure coefficient more significantly. Moreover, the soil friction and the wall friction distinctly increase the seismic passive earth pressure just like the static situation. The comparison shows that the results are consistent with the previous work, which verifies its validity.
基金The National Natural Science Foundation of China(No.51675098)。
文摘To reduce the complexity of the configuration and control strategy for shoulder rehabilitation exoskeleton,a 2R1R1P2R serial of shoulder exoskeleton based on gravity balance is proposed.Based on three basic rotatory shoulder joints,an exact kinematic constraint system can be formed between the exoskeleton and the upper arm by introducing a passive sliding pair and a center of glenohumeral(CGH)unpowered compensation mechanism,which realizes the human-machine kinematic compatibility.Gravity balance is used in the CGH compensation mechanism to provide shoulder joint support.Meanwhile,the motion of the compensation mechanism is pulled by doing reverse leading through the arm to realize the kinematic self-adaptive,which decreases control complexity.Besides,a simple and intuitive spring adjustment strategy is proposed to ensure the gravity balance of any prescribed quality.Furthermore,according to the influencing factors analysis of the scapulohumeral rhythm,the kinematic analysis of CGH mechanism is performed,which shows that the mechanism can fit the trajectory of CGH under various conditions.Finally,the dynamic simulation of the mechanism is carried out.Results indicate that the compensation torques are reduced to below 0.22 N·m,and the feasibility of the mechanism is also verified.
文摘This paper describes a precise method combining numerical analysis and limit equilibrium theory to determine potential slip surfaces in soil slopes. In this method, the direction of the critical slip surface at any point in a slope is determined using the Coulomb’s strength principle and the extremum principle based on the ratio of the shear strength to the shear stress at that point. The ratio, which is considered as an analysis index, can be computed once the stress field of the soil slope is obtained. The critical slip direction at any point in the slope must be the tangential direction of a potential slip surface passing through the point. Therefore, starting from a point on the top of the slope surface or on the horizontal segment outside the slope toe, the increment with a small distance into the slope is used to choose another point and the corresponding slip direction at the point is computed. Connecting all the points used in the computation forms a potential slip surface exiting at the starting point. Then the factor of safety for any potential slip surface can be computed using limit equilibrium method like Spencer method. After factors of safety for all the potential slip surfaces are obtained, the minimum one is the factor of safety for the slope and the corresponding potential slip surface is the critical slip surface of the slope. The proposed method does not need to pre-assume the shape of potential slip surfaces. Thus it is suitable for any shape of slip surfaces. Moreover the method is very simple to be applied. Examples are presented in this paper to illustrate the feasibility of the proposed method programmed in ANSYS software by macro commands.
基金Project(2007CB714006) supported by the National Basic Research Program of China
文摘In order to exactly provide scientific basis for pressure dynamic balance control of working chamber of earth pressure balance shield (EPBS),study on optimal arrangement of pressure measurement points in working chamber was conducted. Based on mathematical description of optimal arrangement for pressure measurement points,fuzzy clustering analysis and discriminant analysis were used to divide pressure regions of nodes on bulkhead. Finally,the selection method of optimal measurement points was proposed,and by selecting d6.28 m EPBS as study object,the case study was conducted. By contrast,based on optimal arrangement scheme of pressure measurement points,through adopting weighted algorithm,the absolute error mean of equivalent pressure of working chamber is the smallest. In addition,pressure curve of optimal arrangement points presents parabola,and it can show the state of pressure distribution on bulkhead truly. It is concluded that the optimal arrangement method of pressure measurement points in working chamber is effective and feasible,and the method can provide basis for realizing high precision pressure control of EPBS.
基金Project(2015M580702)supported by the China Postdoctoral Science FoundationProject(51608541)supported by the National Natural Science Foundation of ChinaProject(2014122006)supported by the Guizhou Provincial Department of Transportation Foundation,China
文摘Two calculation modes for the effect of external load on slope stability, i.e., mode I in which the external load is thought to act on slope surface, and mode II in which the external load is thought to act on slip surface along the force action line, were considered. Meanwhile, four basic distribution patterns of external load were used, of which complex external loads could be composed. In analysis process, several limit equilibrium methods, such as Swedish method, simplified Bishop method, simplified Janbu method, Spencer method, Morgenstern-Price(M-P) method, Sarma method, and unbalanced thrust method, were also adopted to contrast their differences in slope stability under the external load. According to parametric analysis, some conclusions can be obtained as follows:(1) The external load, with the large magnitude, small inclination angle, and acting position close to the slope toe,has more positive effect on slope stability;(2) The results calculated using modes I and II of external load are similar, indicating that the calculation mode of external load has little influence on slope stability;(3) If different patterns of external loads are equivalent to each other, their slope stability under these external loads are the same, and if not, the external load leads to the better slope stability,as action position of the resultant force for external load is closer to the lower sliding point of slip surface.
文摘The selective precipitation of zinc from zinc-nickel sulfate solution with the Zn/Ni molar ratio of20:1was studied.Dropwise addition of0.5mol/L NaOH solution into the zinc-nickel sulfate solution containing0,0.01,0.02,0.03and0.04mol/L ethylene diamine tetraacetate(EDTA)as a chelating agent was done.The equilibrium analysis of precipitation pathway was performed using Visual MINTEQ program.The equilibrium analysis showed that the presence of small amounts of EDTA can prevent nickel precipitation in alkaline conditions without any negative effect on zinc precipitation.On this basis,more than90%of zinc could be precipitated as a product with about50%Zn and only0.11%Ni at pH=9.0merely as a result of the presence of0.03mol/L EDTA in the solution.The stirring time of120min after precipitation was found to be essential for more complete separation.The X-ray diffraction studies on the precipitate revealed that the precipitated phase was Zn4(OH)6SO4.4H2O.
基金Supported by the National Natural Science Foundation of China (20976035, 21076059) the Natural Science Foundation of Hebei Province (B2010000019)
文摘Toluene-2,4-bisurea (TBU) is an important intermediate for urea route to dimethyl toluene-2,4-dicarbamate and the study on TBU synthesis via the reaction of 2,4-toluene diamine (TDA) and urea is of great significance. Firstly, thermodynamic analysis shows that the reaction is exothermic and a high equilibrium conversion of TDA is expected due to its large reaction equilibrium constant. Secondly, under the suitable reaction conditions, 130 °C, 7 h, and molar ratio of TDA/zinc acetate/urea/sulfolane 1/0.05/3.5/10, TDA conversion is 54.3%, and TBU yield and selectivity are 39.8% and 73.3% respectively. Lastly, the synthesis of TBU is a 1st order reaction with respect to TDA and the reaction kinetics model is established. This work will provide useful information for commercializing the urea route to toluene-2,4-dicarbamate (TDC).