A Novel Lignan Glucoside from Forsythia suspensa Vahl

从连翘果实中分离得到了五个单体化合物，根据理化性质和光谱分析鉴定为：对－羟基苯乙酸［ｐ－ｈｙｄｒｏｘｙｐｈｅｎｙｌａｃｅｔｉｃａｃｉｄ］（１），（＋）松脂素－β－Ｄ－葡萄糖甙［（＋）ｐｉｎｏｒｅｓｉｎｏｌ－β－Ｄ－ｇｌｕｃｏｓｉｄｅ］（２），（＋）表松脂素－４－β－Ｄ－葡萄糖甙［（＋）ｅｐｉｐｉｎｏｒｅｓｉｎｏｌ－４－β－Ｄ－ｇｌｕｃｏｓｉｄｅ］（３），（＋）松脂素单甲基醚－β－Ｄ－葡萄糖甙［（＋）ｐｉｎｏｒｅｓｉｎｏｌｍｏｎｏｍｅｔｈｙｌｅｔｈｅｒ－β－Ｄ－ｇｌｕｃｏｓｉｄｅ］（４），连翘甙［ｐｈｉｌｙｒｉｎ］（５）。其中３未见文献报道。

A New Lignan from Boschniakia himalaica

From the ethanol extract of the whole plant of Boschniakia himalaica Hook. f. et. Thoms, a new and two known lignans have been isolated and identified as 7-methoxypinoresino 1, pinoresinol 2, and pinoresinol-O--D-glucopyranoside 3 respectively. Their structures have been established by spectroscopic methods.

HPLC法同时检测16种五加属植物中14种苯丙素类成分

目的建立以HPLC法同时检测16种33批五加属植物中紫丁香苷、绿原酸、咖啡酸、对香豆酸、阿魏酸、ethylsyringin、ethylconiferin、(+)-梣皮树脂醇、(±)-松脂素、(±)-丁香脂素、taiwanin C、savinin、helioxanthin、(-)-sesamin 14种苯丙素类成分的含量。方法采用Promosil C18柱(250 mm×4.6 mm,5μm);流动相为乙腈-0.1%磷酸水溶液,梯度洗脱,体积流量1mL/min;柱温30℃;检测波长280 nm。结果在优化的色谱条件下,14种成分在测定的质量浓度范围内线性关系良好,r均大于0.999 1,方法的精密度、稳定性、重复性以及回收率良好。结论建立的HPLC法可用于同时检测五加属植物中14种苯丙素类化学成分的含量,该方法快速、准确,有较好的重现性和稳定性,可为该属植物的进一步研究提供参考。

Lignanoids from Solanum lyratum

In the present study,we aimed to investigate the chemical constituents from Solanum lyratum.The constituents were separated by column chromatography on silica gel,Sephadex LH-20 and preparative HPLC.Their structures were elucidated by spectroscopic means.A total of 13 compounds were isolated from S.lyraturn and identified as syringin(1),(+)-isolariciresinol(2),(+)-syringaresinol(3),leptolepisol D(4),(-)-secoisolariciresinol(5),(-)-epi-syringaresinol(6),aviculin(7),zhebeiresinol(8),ciwujiatone(9),(-)-(7′S,8S,8′R)-4,4′-dihydroxy-3,3′,5,5′-tetramethoxy-7′,9-epoxylignan-9′-ol-7-one(10),(+)-lariciresinol(11),(+)-pinoresinol(12)and(+)-medioresinol(13).All the compounds were isolated from S.lyratum for the first time.