Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics releva...Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics relevant to the users in an ever-shifting environment, the Banco de Portugal decided to explore the largely unused statistical potential of the available micro-databases and to integrate the existing administrative and survey data, thus enhancing the basic information infrastructure while protecting confidentiality. This presentation will address the benefits and problems to be dealt with when two or more data-sources are to be integrated.展开更多
To address the controversial issue of the toxicity of dental alloys and silver nanoparticles in medical ap- plications, an in vivo-like LO2 3-D model was constructed within polyvinylidene fluoride hollow fiber materia...To address the controversial issue of the toxicity of dental alloys and silver nanoparticles in medical ap- plications, an in vivo-like LO2 3-D model was constructed within polyvinylidene fluoride hollow fiber materials to mimic the microenvironment of liver tissue. The use of microscopy methods and the measurement of liver-specific functions optimized the model for best cell performances and also proved the superiority of the 3-D LO2 model when compared with the traditional monolayer model. Toxicity tests were conducted using the newly constructed model, finding that four dental castings coated with silver nanoparticles were toxic to human hepatocytes after cell viability assays. In general, the toxicity of both the castings and the coated silver nanoparticles aggravated as time increased, yet the nanoparticles attenuated the general toxicity by preventing metal ion release, especially at high concentrations.展开更多
文摘Data are critically important to good decision-making. In an increasingly complex economy, conventional data collecting schemes are no longer sufficient. To deal with the challenge of maintaining its statistics relevant to the users in an ever-shifting environment, the Banco de Portugal decided to explore the largely unused statistical potential of the available micro-databases and to integrate the existing administrative and survey data, thus enhancing the basic information infrastructure while protecting confidentiality. This presentation will address the benefits and problems to be dealt with when two or more data-sources are to be integrated.
基金Project supported by the Zhejiang Provincial Natural Science Foundation of China(No.LZ14C200001)the Public Welfare Project of Science Technology Department of Zhejiang Province(No.2013c33139),China
文摘To address the controversial issue of the toxicity of dental alloys and silver nanoparticles in medical ap- plications, an in vivo-like LO2 3-D model was constructed within polyvinylidene fluoride hollow fiber materials to mimic the microenvironment of liver tissue. The use of microscopy methods and the measurement of liver-specific functions optimized the model for best cell performances and also proved the superiority of the 3-D LO2 model when compared with the traditional monolayer model. Toxicity tests were conducted using the newly constructed model, finding that four dental castings coated with silver nanoparticles were toxic to human hepatocytes after cell viability assays. In general, the toxicity of both the castings and the coated silver nanoparticles aggravated as time increased, yet the nanoparticles attenuated the general toxicity by preventing metal ion release, especially at high concentrations.
