By ECH under a steady By field, a closed field equilibrium of a low aspect ratio as low as R/a = 1.4 is spontaneously formed in the LATE device. After the spontaneous formation, the plasma current has increased furthe...By ECH under a steady By field, a closed field equilibrium of a low aspect ratio as low as R/a = 1.4 is spontaneously formed in the LATE device. After the spontaneous formation, the plasma current has increased further up to Ip = 7.2 kA by 2.45 GHz, 30 kW and Ip = 11 kA by 5 GHz, 120 kW, by increasing the microwave power with a slow ramp of By for the equilibrium of the plasma loop at larger currents. Both amount to 12% of the total toroidai coil current. ECH/ECCD at 2nd harmonic resonance of EBW supports the plasma. An outline of the theoretical considerations for the formation process is presented.展开更多
Electron orbits under the external vertical field （Bv） and the self poloidal field of the toroidal plasma current in a toroidal geometry are investigated by using analytic model fields in order to search for the con...Electron orbits under the external vertical field （Bv） and the self poloidal field of the toroidal plasma current in a toroidal geometry are investigated by using analytic model fields in order to search for the conditions of occurence of appropriate confinement asymmetry of fast electrons along the field lines. This asymmetry efficiently and quickly generates a toroidal current, which may close the field lines in ECH-started plasmas. It is analytically shown that the characteristics of confinement asymmetry depend on the product of the major radius and the strength of the external vertical field. The results suggest that in large devices By should be lowered and also some artificial means to speed up the pitch angle scattering for the fast electrons at a higher energy range are beneficial to generate the toroidal current in order to close the filed展开更多
Possibility of the measurement of radiated waves derived from the thermally emitted electron Bernstein wave （EBW） is numerically investigated based on the assumption of the super dense core （SDC） plasma generated ...Possibility of the measurement of radiated waves derived from the thermally emitted electron Bernstein wave （EBW） is numerically investigated based on the assumption of the super dense core （SDC） plasma generated in LHD. EBW that is thermally emitted in the electron cyclotron resonance （ECR） layer may couple with the electromagnetic wave and be emitted to the vacuum via the EBW-extraordinary-ordinary （B-X-O） mode conversion process. We consider the use of one of the transmission lines for electron cyclotron heating （ECH） in LHD as a receiving system of the emission. It is derived that the waves in the fundamental cyclotron frequency range are emitted as the EBW near their upper hybrid resonance （UHR） layer outside the last close flux surface （LCFS）. On the other hand, waves in the second harmonics cyclotron frequency range are emitted in the core region. It means that successful measurement of waves of the second harmonic frequency range emitted from extremely high dense core plasma with setting an aim angle for receiving indicates a possibility of the second harmonic ECH by EBW in the core region with setting the same aim angle and the same polarization for launching.展开更多
目的探讨胃衡汤调控核因子E2相关因子2(Nrf2)-Kelch样环氧氯丙烷相关蛋白(Keap)信号通路抑制老年胃癌前病变(Precancerous lesions of gastric cancer,PLGC)患者氧化应激反应的作用。方法选取2022年3月-2023年3月期间于南京中医药大学...目的探讨胃衡汤调控核因子E2相关因子2(Nrf2)-Kelch样环氧氯丙烷相关蛋白(Keap)信号通路抑制老年胃癌前病变(Precancerous lesions of gastric cancer,PLGC)患者氧化应激反应的作用。方法选取2022年3月-2023年3月期间于南京中医药大学第二附属医院消化腔镜中心和脾胃病科就诊的PLGC老年患者60例,按随机数字表法分为基础治疗组与胃衡汤治疗组,每组各30例。另选择同期常规胃镜体检的慢性浅表性胃炎患者30例为对照组。对照组仅入组接受研究相关指标检测,不予治疗。基础治疗组患者给予雷贝拉唑钠肠溶胶囊,胃衡汤组在基础治疗组上加用胃衡汤治疗,均治疗6个月。观察比较两组PLGC患者临床疗效、安全性,治疗前后中医证候评分、胃镜病理分级及Nrf2-Keap通路相关蛋白检测。结果治疗后胃衡汤治疗组中医证候疗效总有效率93.33%(28/30)明显高于基础治疗组76.67%(23/30),差异有统计学意义(P<0.05)。治疗后胃衡汤治疗组病理组织学疗效总有效率83.33%(25/30)明显高于基础治疗组63.33%(19/30),差异有统计学意义(P<0.05)。治疗后两组患者中医证候各项积分及总积分均较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组中医证候各项积分及总积分均明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗后两组患者胃黏膜组织学各项积分及总分均较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组胃黏膜组织学各项积分及总分均明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗后两组患者Nrf2和SOD表达高于治疗前,Keap1和MDA表达较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组Nrf2和SOD表达明显高于基础治疗组,Keap1和MDA表达明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗期间,两组患者治疗前后肝肾功能、三大常规及心电图检查均未发现异常。结论胃衡汤治疗老年PLGC能够改善临床症状,抑制甚至逆转病理学改变,提高治疗效果,其机制与调节Nrf2-Keap信号通路而抑制氧化应激反应有关。展开更多
基金supported in part by the JSPS-CAS Core University Program in the field of Plasma and Nuclear Fusion
文摘By ECH under a steady By field, a closed field equilibrium of a low aspect ratio as low as R/a = 1.4 is spontaneously formed in the LATE device. After the spontaneous formation, the plasma current has increased further up to Ip = 7.2 kA by 2.45 GHz, 30 kW and Ip = 11 kA by 5 GHz, 120 kW, by increasing the microwave power with a slow ramp of By for the equilibrium of the plasma loop at larger currents. Both amount to 12% of the total toroidai coil current. ECH/ECCD at 2nd harmonic resonance of EBW supports the plasma. An outline of the theoretical considerations for the formation process is presented.
文摘Electron orbits under the external vertical field （Bv） and the self poloidal field of the toroidal plasma current in a toroidal geometry are investigated by using analytic model fields in order to search for the conditions of occurence of appropriate confinement asymmetry of fast electrons along the field lines. This asymmetry efficiently and quickly generates a toroidal current, which may close the field lines in ECH-started plasmas. It is analytically shown that the characteristics of confinement asymmetry depend on the product of the major radius and the strength of the external vertical field. The results suggest that in large devices By should be lowered and also some artificial means to speed up the pitch angle scattering for the fast electrons at a higher energy range are beneficial to generate the toroidal current in order to close the filed
基金supported in part by the JSPS-CAS Core-University program in the field of 'Plasma and Nuclear Fusion'
文摘Possibility of the measurement of radiated waves derived from the thermally emitted electron Bernstein wave （EBW） is numerically investigated based on the assumption of the super dense core （SDC） plasma generated in LHD. EBW that is thermally emitted in the electron cyclotron resonance （ECR） layer may couple with the electromagnetic wave and be emitted to the vacuum via the EBW-extraordinary-ordinary （B-X-O） mode conversion process. We consider the use of one of the transmission lines for electron cyclotron heating （ECH） in LHD as a receiving system of the emission. It is derived that the waves in the fundamental cyclotron frequency range are emitted as the EBW near their upper hybrid resonance （UHR） layer outside the last close flux surface （LCFS）. On the other hand, waves in the second harmonics cyclotron frequency range are emitted in the core region. It means that successful measurement of waves of the second harmonic frequency range emitted from extremely high dense core plasma with setting an aim angle for receiving indicates a possibility of the second harmonic ECH by EBW in the core region with setting the same aim angle and the same polarization for launching.
文摘目的探讨胃衡汤调控核因子E2相关因子2(Nrf2)-Kelch样环氧氯丙烷相关蛋白(Keap)信号通路抑制老年胃癌前病变(Precancerous lesions of gastric cancer,PLGC)患者氧化应激反应的作用。方法选取2022年3月-2023年3月期间于南京中医药大学第二附属医院消化腔镜中心和脾胃病科就诊的PLGC老年患者60例,按随机数字表法分为基础治疗组与胃衡汤治疗组,每组各30例。另选择同期常规胃镜体检的慢性浅表性胃炎患者30例为对照组。对照组仅入组接受研究相关指标检测,不予治疗。基础治疗组患者给予雷贝拉唑钠肠溶胶囊,胃衡汤组在基础治疗组上加用胃衡汤治疗,均治疗6个月。观察比较两组PLGC患者临床疗效、安全性,治疗前后中医证候评分、胃镜病理分级及Nrf2-Keap通路相关蛋白检测。结果治疗后胃衡汤治疗组中医证候疗效总有效率93.33%(28/30)明显高于基础治疗组76.67%(23/30),差异有统计学意义(P<0.05)。治疗后胃衡汤治疗组病理组织学疗效总有效率83.33%(25/30)明显高于基础治疗组63.33%(19/30),差异有统计学意义(P<0.05)。治疗后两组患者中医证候各项积分及总积分均较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组中医证候各项积分及总积分均明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗后两组患者胃黏膜组织学各项积分及总分均较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组胃黏膜组织学各项积分及总分均明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗后两组患者Nrf2和SOD表达高于治疗前,Keap1和MDA表达较治疗前降低,差异有统计学意义(P<0.05);且胃衡汤治疗组Nrf2和SOD表达明显高于基础治疗组,Keap1和MDA表达明显低于基础治疗组,差异有统计学意义(P<0.05)。治疗期间,两组患者治疗前后肝肾功能、三大常规及心电图检查均未发现异常。结论胃衡汤治疗老年PLGC能够改善临床症状,抑制甚至逆转病理学改变,提高治疗效果,其机制与调节Nrf2-Keap信号通路而抑制氧化应激反应有关。
