Background: Posttraumatic Stress Disorder (PTSD) is a psychiatric disorder found in individuals afflicted by a traumatic event including the natural disaster. “Tsunami” occurred in Andaman coast of Thailand on Decem...Background: Posttraumatic Stress Disorder (PTSD) is a psychiatric disorder found in individuals afflicted by a traumatic event including the natural disaster. “Tsunami” occurred in Andaman coast of Thailand on December 26, 2004, in which 33.6% of survivors were diagnosed as PTSD. This study aimed to explore the single nucleotide polymorphism (SNP). rs267943 genotype is located on chromosome 5 in the intron of the death-associated protein 1 (DAP1) gene and psychosocial factors for PTSD. Methods: Participants (N = 1970) were recruited from volunteers who have complete data both of DAP1 gene and psychosocial factor. Results: Using a binary logistic regression model, significant gene-environment interactions were found for the single nucleotide polymorphism (SNP) rs267943 and psychosocial factors including depression (adj. OR = 6.0, 95% CI = 4.29 - 8.39), neurotic personality (adj. OR = 2.73, 95% CI = 2.18 - 3.42), planning (adj. OR = 1.52, 95% CI = 1.20 - 1.93), use of emotional support (adj. OR = 1.32, 95% CI = 1.21 - 1.94) with statistical significant p Conclusion: This study demonstrated that GxE studies can be utilized to shed light on the origins of PTSD.展开更多
Potato is one of the important crops grown in mid and high altitude areas of Ethiopia. Several potato genotypes have been introduced in different parts of this region. However, the stability and performance of these g...Potato is one of the important crops grown in mid and high altitude areas of Ethiopia. Several potato genotypes have been introduced in different parts of this region. However, the stability and performance of these genotypes are not yet assessed. Therefore, the objective of this study was to determine the effect of genotype, environment and their interaction for tuber yield and identify stable potato genotypes. The study was conducted using eight potato genotypes in rainfed production season of years 2010 and 2011 at five potato growing locations in the region. Randomized complete block design with three replications was used for the experiment. Among the testing locations, the superior mean tuber yield (25.43 t/ha) was obtained at Adet while the inferior (13.89 t/ha) was at Injibara. Similarly, among the genotypes, CIP-396004.337 gave the highest mean tuber yield (25.66 t/ha), while CIP-395011.2 gave the lowest (17.78 t/ha). Combined ANOVA indicated that the main effects due to environments, genotypes and genotype by environment interaction were highly significant. The contribution of E, G and GEI to the total variation in tuber yield was about 47.11%, 8.83% and 44.07%, respectively. The GEI was further partitioned using GGE biplot model. The first two principal components obtained by singular value decomposition of the centered data of tuber yield explained 71.26% of the total variability caused by (G + GE). Out of these variations, PC1 and PC2 accounted 51.24% and 20.02% variability, respectively. GGE biplot view of this study identified Serinka as ideal testing location and CIP-396004.337 as ideal genotype for Amhara region in Ethiopia.展开更多
In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate ...In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate genotypexenvironmental interactions for adaptability and stability at the age of 30 months in three geographical locations in the state of Punjab, India. Clone 124 had maximum adaptability and stability （bi = 1.04） to perform exceedingly well over the locations. Clones 36 and 1 were stable with mean regression coefficient of 0.84 and 1.22, respectively. Nonetheless, clone 4 1 performed exceedingly well for all the characters to attain maximum population mean, and the perform- ance varied substantially across the locations. Therefore, clone 41 was considered as productive but non-adaptive clone. Though some of the clones were sensitive to sites, 14 clones for height, 16 for collar diameter, 12 for DBH and 7 for volume were relatively un-sensitive with higher regression coefficient. Nonetheless, clone 124 was the most Stable with average bi value of 1.04 and productive, which could play an important role in future breeding and commercial deployment of stable and produc- tive planting stock of Dalbergia sissoo.展开更多
Twenty nine cowpea genotypes, including four Ugandan genotypes, were evaluated for grain yield, protein stability and adaptability under diverse environments in a randomized complete block design with three replicatio...Twenty nine cowpea genotypes, including four Ugandan genotypes, were evaluated for grain yield, protein stability and adaptability under diverse environments in a randomized complete block design with three replications. The analysis showed that cowpea grain yield and protein content were significantly (P < 0.01) affected by genotypes (G), environments (E), and interaction (G x E). Genotypes C2T and C2I had the highest grain yield and protein content respectively, but both were only adapted to specific environments. Genotypes C1J, C1V, C2A, C2O, and C2R were adapted to three environments with high yield which was stable. Similarly, genotypes BRS Pujante, C1J, C2Q and CIT also expressed high protein levels with high stability and wide adaptability. The study further revealed that Namulonge 2014B, Serere 2014A, Serere 2014B and Serere were the most favorable environments for obtaining high yield and protein respectively, because at these four environments, mean yield and protein were higher than the overall mean. All Brazilian genotypes had high protein levels compared to Ugandan genotypes indicating the potential of Brazilian genotypes in improving cowpea seed protein content in Uganda.展开更多
Genotype-by-environment interactions (G′E) are commonly observedfor quantitative traits. In the present study, a doubled haploid (DH) population and its genetic linkage map were used to comparatively study QTLs in sa...Genotype-by-environment interactions (G′E) are commonly observedfor quantitative traits. In the present study, a doubled haploid (DH) population and its genetic linkage map were used to comparatively study QTLs in salt stress and nonstress environments. A total of 24 QTLs were detected for five agronomic traits, which were distributed on all the chromosomes except 9 and 11. Under the salt stress, nine (37.5%) QTLs were detected, including one for 1 000-grain weight (GW), two for heading date (HD), one for plant height (PH), two for grains per panicle (GPP), and three for effective tillers (ET), while in the nonstress environment, 17 QTLs (70.8%) were detected, including five for GW, six for HD, three for PH, two for GPP, and one for ET. Two QTLs (8.3%) were consistently detected in both environments. One was identified on chromosome 4 for HD and the other on Chr.6 for GPP. Furthermore, three regions carrying multiple QTLs were identified on chromosomes 1, 4 and 8 respectively. For example, on chromosome 8, three QTLs for HD, GW and PH, respectively were identified between RG885-GA408 in nonstress environment, but not in the stress environment. The comparative study of QTLs detected in extremely different (salt stress and nonstress) environments revealed that there existed several QTLs for important agronomic traits on chromosome 8 which were affected significantly by salt stress.展开更多
Improved adaptation of winter wheat （Triticum aestivum L.） to drought and heat may be influenced by days to heading, plant height, biomass, canopy temperature （CT） at grain fil ing, and rate of senescence. This st...Improved adaptation of winter wheat （Triticum aestivum L.） to drought and heat may be influenced by days to heading, plant height, biomass, canopy temperature （CT） at grain fil ing, and rate of senescence. This study shows that, under supplemental irrigation or rainfed conditions, days to heading and plant height together explain up to 68%of grain yield （GY） variation, and these associations were further confirmed in several locations across West and Central Asia. Days to heading can be slightly reduced below that of check line Karahan to further improve GY while avoiding the effect of late frosts. Plant height has been decreased in recent germplasm, but further reductions below that of check line Karahan could stil improve GY in a wide range of environ-ments. However, in Iranian sites, tal er genotypes showed better adaptation with higher biomass and increased reserves＆amp;nbsp;for grain fil ing. Canopy temperature and rate senescence were not associated with GY. A normalized difference vegetation index, used to estimate biomass （Feekes stages 4-5）, had intermediate heritability across environments and correlated positively with GY under low plant density and should be explored further as a tool for early selection.展开更多
文摘Background: Posttraumatic Stress Disorder (PTSD) is a psychiatric disorder found in individuals afflicted by a traumatic event including the natural disaster. “Tsunami” occurred in Andaman coast of Thailand on December 26, 2004, in which 33.6% of survivors were diagnosed as PTSD. This study aimed to explore the single nucleotide polymorphism (SNP). rs267943 genotype is located on chromosome 5 in the intron of the death-associated protein 1 (DAP1) gene and psychosocial factors for PTSD. Methods: Participants (N = 1970) were recruited from volunteers who have complete data both of DAP1 gene and psychosocial factor. Results: Using a binary logistic regression model, significant gene-environment interactions were found for the single nucleotide polymorphism (SNP) rs267943 and psychosocial factors including depression (adj. OR = 6.0, 95% CI = 4.29 - 8.39), neurotic personality (adj. OR = 2.73, 95% CI = 2.18 - 3.42), planning (adj. OR = 1.52, 95% CI = 1.20 - 1.93), use of emotional support (adj. OR = 1.32, 95% CI = 1.21 - 1.94) with statistical significant p Conclusion: This study demonstrated that GxE studies can be utilized to shed light on the origins of PTSD.
基金following grants:HD042608, NICHD, NIDA, and the Office of the Director, U.S. PHS (PI Years 1–5: David Reiss, MD PI Years 6–10: Leslie Leve, PhD)DA020585, NIDA, NIMH, and the Office of the Director, U.S. PHS (PI:Jenae Neiderhiser, PhD)
文摘Potato is one of the important crops grown in mid and high altitude areas of Ethiopia. Several potato genotypes have been introduced in different parts of this region. However, the stability and performance of these genotypes are not yet assessed. Therefore, the objective of this study was to determine the effect of genotype, environment and their interaction for tuber yield and identify stable potato genotypes. The study was conducted using eight potato genotypes in rainfed production season of years 2010 and 2011 at five potato growing locations in the region. Randomized complete block design with three replications was used for the experiment. Among the testing locations, the superior mean tuber yield (25.43 t/ha) was obtained at Adet while the inferior (13.89 t/ha) was at Injibara. Similarly, among the genotypes, CIP-396004.337 gave the highest mean tuber yield (25.66 t/ha), while CIP-395011.2 gave the lowest (17.78 t/ha). Combined ANOVA indicated that the main effects due to environments, genotypes and genotype by environment interaction were highly significant. The contribution of E, G and GEI to the total variation in tuber yield was about 47.11%, 8.83% and 44.07%, respectively. The GEI was further partitioned using GGE biplot model. The first two principal components obtained by singular value decomposition of the centered data of tuber yield explained 71.26% of the total variability caused by (G + GE). Out of these variations, PC1 and PC2 accounted 51.24% and 20.02% variability, respectively. GGE biplot view of this study identified Serinka as ideal testing location and CIP-396004.337 as ideal genotype for Amhara region in Ethiopia.
文摘In total 36 superior clones of Dalbergia sissoo Roxb., screened from 300 selections conducted in natural and growing range of India and Nepal, were multiplied using single nodal cuttings and estab- lished to evaluate genotypexenvironmental interactions for adaptability and stability at the age of 30 months in three geographical locations in the state of Punjab, India. Clone 124 had maximum adaptability and stability （bi = 1.04） to perform exceedingly well over the locations. Clones 36 and 1 were stable with mean regression coefficient of 0.84 and 1.22, respectively. Nonetheless, clone 4 1 performed exceedingly well for all the characters to attain maximum population mean, and the perform- ance varied substantially across the locations. Therefore, clone 41 was considered as productive but non-adaptive clone. Though some of the clones were sensitive to sites, 14 clones for height, 16 for collar diameter, 12 for DBH and 7 for volume were relatively un-sensitive with higher regression coefficient. Nonetheless, clone 124 was the most Stable with average bi value of 1.04 and productive, which could play an important role in future breeding and commercial deployment of stable and produc- tive planting stock of Dalbergia sissoo.
文摘Twenty nine cowpea genotypes, including four Ugandan genotypes, were evaluated for grain yield, protein stability and adaptability under diverse environments in a randomized complete block design with three replications. The analysis showed that cowpea grain yield and protein content were significantly (P < 0.01) affected by genotypes (G), environments (E), and interaction (G x E). Genotypes C2T and C2I had the highest grain yield and protein content respectively, but both were only adapted to specific environments. Genotypes C1J, C1V, C2A, C2O, and C2R were adapted to three environments with high yield which was stable. Similarly, genotypes BRS Pujante, C1J, C2Q and CIT also expressed high protein levels with high stability and wide adaptability. The study further revealed that Namulonge 2014B, Serere 2014A, Serere 2014B and Serere were the most favorable environments for obtaining high yield and protein respectively, because at these four environments, mean yield and protein were higher than the overall mean. All Brazilian genotypes had high protein levels compared to Ugandan genotypes indicating the potential of Brazilian genotypes in improving cowpea seed protein content in Uganda.
基金the Chinese National Rice Genome Program and the National High-Tech Research Program of China.
文摘Genotype-by-environment interactions (G′E) are commonly observedfor quantitative traits. In the present study, a doubled haploid (DH) population and its genetic linkage map were used to comparatively study QTLs in salt stress and nonstress environments. A total of 24 QTLs were detected for five agronomic traits, which were distributed on all the chromosomes except 9 and 11. Under the salt stress, nine (37.5%) QTLs were detected, including one for 1 000-grain weight (GW), two for heading date (HD), one for plant height (PH), two for grains per panicle (GPP), and three for effective tillers (ET), while in the nonstress environment, 17 QTLs (70.8%) were detected, including five for GW, six for HD, three for PH, two for GPP, and one for ET. Two QTLs (8.3%) were consistently detected in both environments. One was identified on chromosome 4 for HD and the other on Chr.6 for GPP. Furthermore, three regions carrying multiple QTLs were identified on chromosomes 1, 4 and 8 respectively. For example, on chromosome 8, three QTLs for HD, GW and PH, respectively were identified between RG885-GA408 in nonstress environment, but not in the stress environment. The comparative study of QTLs detected in extremely different (salt stress and nonstress) environments revealed that there existed several QTLs for important agronomic traits on chromosome 8 which were affected significantly by salt stress.
基金The Mexican Ministry of Agriculture,Livestock,Rural Development,Fisheries and Food(SAGARPA) via MasAgro Seeds of Discovery is acknowledged for financial support
文摘Improved adaptation of winter wheat （Triticum aestivum L.） to drought and heat may be influenced by days to heading, plant height, biomass, canopy temperature （CT） at grain fil ing, and rate of senescence. This study shows that, under supplemental irrigation or rainfed conditions, days to heading and plant height together explain up to 68%of grain yield （GY） variation, and these associations were further confirmed in several locations across West and Central Asia. Days to heading can be slightly reduced below that of check line Karahan to further improve GY while avoiding the effect of late frosts. Plant height has been decreased in recent germplasm, but further reductions below that of check line Karahan could stil improve GY in a wide range of environ-ments. However, in Iranian sites, tal er genotypes showed better adaptation with higher biomass and increased reserves＆amp;nbsp;for grain fil ing. Canopy temperature and rate senescence were not associated with GY. A normalized difference vegetation index, used to estimate biomass （Feekes stages 4-5）, had intermediate heritability across environments and correlated positively with GY under low plant density and should be explored further as a tool for early selection.
