目的探讨老年综合评估在老年高血压患者氨氯地平治疗前后中的应用价值。方法整群选取2014年6月—2015年12月该院老年康复科门诊及病房住院的老年高血压患者457例作为研究对象。应用老年综合评估量化表对所有患者进行初次评估,患者应用...目的探讨老年综合评估在老年高血压患者氨氯地平治疗前后中的应用价值。方法整群选取2014年6月—2015年12月该院老年康复科门诊及病房住院的老年高血压患者457例作为研究对象。应用老年综合评估量化表对所有患者进行初次评估,患者应用氨氯地平治疗6个月后再次应用老年综合评估量化表进行评估,观察患者治疗前后各项评估指标的变化情况,分析老年高血压患者中不同症状的表现情况以及氨氯地平对老年综合症的影响。结果不同高血压分级患者在体位性低血压(19.70% vs 14.61% vs 24.06%)、GDS-15≥6分(6.06% vs 10.11% vs 21.23%)、听力功能障碍患病率(40.91% vs 57.87% vs 45.28%)比较差异有统计学意义(P<0.05);并且氨氯地平治疗后血压达标患者体位性低血压发生率与治疗后未达标患者比较差异有统计学意义(17.67%vs24.50%P<0.05),但其他症状比较差异无统计学意义(P>0.05)。结论老年高血压患者易发生各种老年综合症,并且随着病程的延长极易导致多种共病、体位性低血压、脉压差大等症状,采用氨氯地平规范治疗可有效缓解患者临床症状与指标,对维持患者功能状况与生活质量具有重要意义。展开更多
Protoplast fusion was induced between sainfoin and alfalfa by an improved polyethyleneglycol (PEG) method. The intergeneric somatic calluses were selected based on complementation of hydroxyproline-resistance of sainf...Protoplast fusion was induced between sainfoin and alfalfa by an improved polyethyleneglycol (PEG) method. The intergeneric somatic calluses were selected based on complementation of hydroxyproline-resistance of sainfoin and hormone autonomy growth of alfalfa transformation cell line. 17 somatic hybrid plantlets were regenerat-ed. PEG could induce the tight agglutination of protoplasts. During diluting and washing process, cyclization of the linked membrane and formation of vesicle-like structures were observed, resulting in protoplast fusion. 5%-10% glycerol supplemented in the fusion inducing solution markedly increased the frequency of heterogeneous fusion. Better fusion results were obtained when mixed protoplast suspension was dripped in petri dishes in which PEG solution was previously placed. Chromosome number of regenerated hybrid buds varied from 30 to 60. The genome of hybrids in-cluded the small chromosome from sainfoin and two chromosomes with two clear constrictions from alfalfa. The hybrid-ity of obtained hybrid calluses was confirmed by their isozyme banding patterns and their nopaline synthetase activity.展开更多
文摘目的探讨老年综合评估在老年高血压患者氨氯地平治疗前后中的应用价值。方法整群选取2014年6月—2015年12月该院老年康复科门诊及病房住院的老年高血压患者457例作为研究对象。应用老年综合评估量化表对所有患者进行初次评估,患者应用氨氯地平治疗6个月后再次应用老年综合评估量化表进行评估,观察患者治疗前后各项评估指标的变化情况,分析老年高血压患者中不同症状的表现情况以及氨氯地平对老年综合症的影响。结果不同高血压分级患者在体位性低血压(19.70% vs 14.61% vs 24.06%)、GDS-15≥6分(6.06% vs 10.11% vs 21.23%)、听力功能障碍患病率(40.91% vs 57.87% vs 45.28%)比较差异有统计学意义(P<0.05);并且氨氯地平治疗后血压达标患者体位性低血压发生率与治疗后未达标患者比较差异有统计学意义(17.67%vs24.50%P<0.05),但其他症状比较差异无统计学意义(P>0.05)。结论老年高血压患者易发生各种老年综合症,并且随着病程的延长极易导致多种共病、体位性低血压、脉压差大等症状,采用氨氯地平规范治疗可有效缓解患者临床症状与指标,对维持患者功能状况与生活质量具有重要意义。
基金Project supported by the National Natural Science Foundation of China.
文摘Protoplast fusion was induced between sainfoin and alfalfa by an improved polyethyleneglycol (PEG) method. The intergeneric somatic calluses were selected based on complementation of hydroxyproline-resistance of sainfoin and hormone autonomy growth of alfalfa transformation cell line. 17 somatic hybrid plantlets were regenerat-ed. PEG could induce the tight agglutination of protoplasts. During diluting and washing process, cyclization of the linked membrane and formation of vesicle-like structures were observed, resulting in protoplast fusion. 5%-10% glycerol supplemented in the fusion inducing solution markedly increased the frequency of heterogeneous fusion. Better fusion results were obtained when mixed protoplast suspension was dripped in petri dishes in which PEG solution was previously placed. Chromosome number of regenerated hybrid buds varied from 30 to 60. The genome of hybrids in-cluded the small chromosome from sainfoin and two chromosomes with two clear constrictions from alfalfa. The hybrid-ity of obtained hybrid calluses was confirmed by their isozyme banding patterns and their nopaline synthetase activity.
