A microwave-induced thermoacoustic imaging(MITAT)system is a non-destructive physical medical imaging method that combines the advantages of the high contrast of microwave imaging and the high resolution of ultrasound...A microwave-induced thermoacoustic imaging(MITAT)system is a non-destructive physical medical imaging method that combines the advantages of the high contrast of microwave imaging and the high resolution of ultrasound imaging.It uses the microwave as the excitation source and ultrasound as the information carrier.When different kinds of biological tissue absorb electromagnetic energy,it results in localized temperature rises.The thermal expansion will induce ultrasonic signals(i.e.,thermoacoustic signals),known as the thermoacoustic effect.The microwave absorption image of the sample can be reconstructed by algorithm processing.The MITAT contrast depends on different dielectric parameters of different kinds of tissue.We introduce the developed system and its application.In addition,the challenges and prospects of MITAT for further development are discussed.展开更多
Microwave-induced thermo-acoustic tomography (MITAT) is a promising technique with great potential in biomedical imaging. It has both the high contrast of the microwave imaging and the high resolution of the ultrasoun...Microwave-induced thermo-acoustic tomography (MITAT) is a promising technique with great potential in biomedical imaging. It has both the high contrast of the microwave imaging and the high resolution of the ultrasound imaging. In this paper, the proportional relationship between the absorbed microwave energy distribution and the induced ultrasound source distribution is derived. Further, the time reversal mirror (TRM) technique based on the pseudo-spectral time domain (PSTD) method is applied to MITAT system. The simulation results show that high contrast and resolution can be achieved by the TRM technique based on PSTD method even for the received signals with very low signal-to-noise ratio (SNR) and the model parameter with random fluctuation.展开更多
Due to its advantages in both contrast and resolution compared with conventional microwave or ultrasound imaging system, microwave-induced thermo-acoustic tomography (MITAT) has received more and more concerns in biol...Due to its advantages in both contrast and resolution compared with conventional microwave or ultrasound imaging system, microwave-induced thermo-acoustic tomography (MITAT) has received more and more concerns in biologic tissue image field. In this paper, an integrated prototype of MITAT system is presented. Using this system, some basic experiments for biologic tissue objects with high water-content imbedded in fatty material have been done. In the MITAT experiments, the signals generated by two porcine muscle tissue strips with millimeter order scale in cross-section were collected. Images with both good contrast and resolution were obtained. In order to demonstrate the advantages of MITAT, some ultrasonic experiments were studied using a commercial ultrasonic linear array system. The comparisons of the results of both systems show the good performance of the MITAT prototype system for the detection of high water content targets, which is generally the same as the tumor in biologic tissue.展开更多
基金the National Natural Science Foundation of China under Grant No.12304533Start-up Foundation for Ph.D.of Southwest University of Science and Technology under Grant No.20zx7120.
文摘A microwave-induced thermoacoustic imaging(MITAT)system is a non-destructive physical medical imaging method that combines the advantages of the high contrast of microwave imaging and the high resolution of ultrasound imaging.It uses the microwave as the excitation source and ultrasound as the information carrier.When different kinds of biological tissue absorb electromagnetic energy,it results in localized temperature rises.The thermal expansion will induce ultrasonic signals(i.e.,thermoacoustic signals),known as the thermoacoustic effect.The microwave absorption image of the sample can be reconstructed by algorithm processing.The MITAT contrast depends on different dielectric parameters of different kinds of tissue.We introduce the developed system and its application.In addition,the challenges and prospects of MITAT for further development are discussed.
基金Supported by the National Natural Science Foundation of China(Grant No.60771042)the National Hi-Tech Research and Development Program("863"Project)(Grant No.2007AA12Z159)+2 种基金111Project(Grant No.B07046)SiChuan Excellent Youth Foun-dation(Grant No.08ZQ026-039)Program for New Century Excellent Talents in University of China and Program for Changjiang Scholars
文摘Microwave-induced thermo-acoustic tomography (MITAT) is a promising technique with great potential in biomedical imaging. It has both the high contrast of the microwave imaging and the high resolution of the ultrasound imaging. In this paper, the proportional relationship between the absorbed microwave energy distribution and the induced ultrasound source distribution is derived. Further, the time reversal mirror (TRM) technique based on the pseudo-spectral time domain (PSTD) method is applied to MITAT system. The simulation results show that high contrast and resolution can be achieved by the TRM technique based on PSTD method even for the received signals with very low signal-to-noise ratio (SNR) and the model parameter with random fluctuation.
基金Supported by the National Natural Science Foundation of China (Grant No. 60771042)National High Technology Research and Development Program (Grant No. 2007AA12Z159)+2 种基金111 Project (Grant No. B07046)Sichuan Excellent Youth Foundation (Grant No. 08ZQ026-039)Program for New Century Excellent Talents in University of China and Program for Changjiang Scholars
文摘Due to its advantages in both contrast and resolution compared with conventional microwave or ultrasound imaging system, microwave-induced thermo-acoustic tomography (MITAT) has received more and more concerns in biologic tissue image field. In this paper, an integrated prototype of MITAT system is presented. Using this system, some basic experiments for biologic tissue objects with high water-content imbedded in fatty material have been done. In the MITAT experiments, the signals generated by two porcine muscle tissue strips with millimeter order scale in cross-section were collected. Images with both good contrast and resolution were obtained. In order to demonstrate the advantages of MITAT, some ultrasonic experiments were studied using a commercial ultrasonic linear array system. The comparisons of the results of both systems show the good performance of the MITAT prototype system for the detection of high water content targets, which is generally the same as the tumor in biologic tissue.
