The surface-enhanced Raman scattering(SERS) optical fiber probes were successfully prepared by self-assembling on polyelectrolyte multilayers. Gold nanorods(Au NRs) were used as SERS enhancement material to give excel...The surface-enhanced Raman scattering(SERS) optical fiber probes were successfully prepared by self-assembling on polyelectrolyte multilayers. Gold nanorods(Au NRs) were used as SERS enhancement material to give excellent biological affinity and stability to the SERS optical fiber probes. Au NRs were synthesized by seed growth method. The synergistic effect between AgNO_(3) and surfactant was investigated, and the highest yield was found when AgNO_(3) was 500 uL. Meanwhile, different SERS optical fiber probes were obtained by selecting silane coupling agent, polyelectrolyte multilayer and graphene oxide(GO) to treat quartz fiber. It was found that the SERS optical fiber probes obtained by the self-assembled on polyelectrolyte multilayers method performed better than those by other methods. In addition, Mapping was combined with finite element simulation to analyze the electromagnetic field distribution at the fiber end face.The electromagnetic field distribution of Au NRs was investigated, the difference of electromagnetic field intensity around the Au NRs with different arrangements was compared, the strongest signal was obtained when the Au NRs were head-to-head. Finally, sensitivity of the optimized SERS optical fiber probes could reach 10^(-9)mol/L, with excellent stability and repeatability.展开更多
We demonstrated a chemical process in the fabrication of a SERS fiber probe with an ultrahigh sensitivity.The synthesis was carried out by preparing Au@Ag core-shell nanorods (Au@Ag-NRs) selfassembled on polyelectroly...We demonstrated a chemical process in the fabrication of a SERS fiber probe with an ultrahigh sensitivity.The synthesis was carried out by preparing Au@Ag core-shell nanorods (Au@Ag-NRs) selfassembled on polyelectrolyte (PE) multilayers,for which Au@Ag-NRs were controlled by adjusting the silver layer thickness.The effect of silver layer thickness of Au@Ag-NRs on the SERS performance of the fiber probe was investigated.The SERS fiber probe shows the best performance when the silver layer thickness is controlled at 8.57 nm.Under the condition of optimizing silver layer thickness,the fiber probe exhibits ultra-high sensitivity (i e,10^(-10) M crystalline violet,CV),good reproducibility (i e,RSD of 3.5%) and stability.Besides,electromagnetic field distribution of the SERS fiber probe was also investigated.The strongest enhancement is found within the core of fiber,whereas a weakened electromagnetic field exists in the fiber cladding layer.The SERS fiber probe can be a good candidate in ultra-trace detection for biomedical and environmental areas.展开更多
Surface-enhanced Raman scattering(SERS)substrates based on chemical mechanism(CM)have received widespread attentions for the stable and repeatable signal output due to their excellent chemical stability,uniform molecu...Surface-enhanced Raman scattering(SERS)substrates based on chemical mechanism(CM)have received widespread attentions for the stable and repeatable signal output due to their excellent chemical stability,uniform molecular adsorption and controllable molecular orientation.However,it remains huge challenges to achieve the optimal SERS signal for diverse molecules with different band structures on the same substrate.Herein,we demonstrate a graphene oxide(GO)energy band regulation strategy through ferroelectric polarization to facilitate the charge transfer process for improving SERS activity.The Fermi level(Ef)of GO can be flexibly manipulated by adjusting the ferroelectric polarization direction or the temperature of the ferroelectric substrate.Experimentally,kelvin probe force microscopy(KPFM)is employed to quantitatively analyze the Ef of GO.Theoretically,the density functional theory calculations are also performed to verify the proposed modulation mechanism.Consequently,the SERS response of probe molecules with different band structures(R6G,CV,MB,PNTP)can be improved through polarization direction or temperature changes without the necessity to redesign the SERS substrate.This work provides a novel insight into the SERS substrate design based on CM and is expected to be applied to other two-dimensional materials.展开更多
基金Funded by National Natural Science Foundation of China (Nos.51372179, 51772224)the Open Projects Foundation of Yangtze Optical Fiber and Cable Joint Stock Limited Company (YOFC)(No.SKLD1705)。
文摘The surface-enhanced Raman scattering(SERS) optical fiber probes were successfully prepared by self-assembling on polyelectrolyte multilayers. Gold nanorods(Au NRs) were used as SERS enhancement material to give excellent biological affinity and stability to the SERS optical fiber probes. Au NRs were synthesized by seed growth method. The synergistic effect between AgNO_(3) and surfactant was investigated, and the highest yield was found when AgNO_(3) was 500 uL. Meanwhile, different SERS optical fiber probes were obtained by selecting silane coupling agent, polyelectrolyte multilayer and graphene oxide(GO) to treat quartz fiber. It was found that the SERS optical fiber probes obtained by the self-assembled on polyelectrolyte multilayers method performed better than those by other methods. In addition, Mapping was combined with finite element simulation to analyze the electromagnetic field distribution at the fiber end face.The electromagnetic field distribution of Au NRs was investigated, the difference of electromagnetic field intensity around the Au NRs with different arrangements was compared, the strongest signal was obtained when the Au NRs were head-to-head. Finally, sensitivity of the optimized SERS optical fiber probes could reach 10^(-9)mol/L, with excellent stability and repeatability.
基金Funded by National Natural Science Foundation of China (Nos.51372179, 51772224)the Open Projects Foundation of Yangtze Optical Fiber and Cable Joint Stock Limited Company (YOFC)(No.SKLD1705)。
文摘We demonstrated a chemical process in the fabrication of a SERS fiber probe with an ultrahigh sensitivity.The synthesis was carried out by preparing Au@Ag core-shell nanorods (Au@Ag-NRs) selfassembled on polyelectrolyte (PE) multilayers,for which Au@Ag-NRs were controlled by adjusting the silver layer thickness.The effect of silver layer thickness of Au@Ag-NRs on the SERS performance of the fiber probe was investigated.The SERS fiber probe shows the best performance when the silver layer thickness is controlled at 8.57 nm.Under the condition of optimizing silver layer thickness,the fiber probe exhibits ultra-high sensitivity (i e,10^(-10) M crystalline violet,CV),good reproducibility (i e,RSD of 3.5%) and stability.Besides,electromagnetic field distribution of the SERS fiber probe was also investigated.The strongest enhancement is found within the core of fiber,whereas a weakened electromagnetic field exists in the fiber cladding layer.The SERS fiber probe can be a good candidate in ultra-trace detection for biomedical and environmental areas.
基金financial supports from the National Natural Science Foundation of China (11974222,12004226,12174229,11904214)Natural Science Foundation of Shandong Province (ZR2022YQ02,ZR2020QA075)+2 种基金Qingchuang Science and Technology Plan of Shandong Province (2021KJ006,2019KJJ014,2019KJJ017)Taishan Scholars Program of Shandong Province (tsqn202306152)China Postdoctoral Science Foundation(2019M662423),Shandong Post-Doctoral Innovation Project (202002021).
文摘Surface-enhanced Raman scattering(SERS)substrates based on chemical mechanism(CM)have received widespread attentions for the stable and repeatable signal output due to their excellent chemical stability,uniform molecular adsorption and controllable molecular orientation.However,it remains huge challenges to achieve the optimal SERS signal for diverse molecules with different band structures on the same substrate.Herein,we demonstrate a graphene oxide(GO)energy band regulation strategy through ferroelectric polarization to facilitate the charge transfer process for improving SERS activity.The Fermi level(Ef)of GO can be flexibly manipulated by adjusting the ferroelectric polarization direction or the temperature of the ferroelectric substrate.Experimentally,kelvin probe force microscopy(KPFM)is employed to quantitatively analyze the Ef of GO.Theoretically,the density functional theory calculations are also performed to verify the proposed modulation mechanism.Consequently,the SERS response of probe molecules with different band structures(R6G,CV,MB,PNTP)can be improved through polarization direction or temperature changes without the necessity to redesign the SERS substrate.This work provides a novel insight into the SERS substrate design based on CM and is expected to be applied to other two-dimensional materials.
基金Jiangsu Specially Appointed Professor program,introduction of Talent Research Start fund of Nanjing Medical University(NMUR2019007)Shanghai Key Lab of Forensic Science,Ministry of Justice,China(Academy of Forensic Science Open Subject)(KF202006)Chunhui Project Foundation of the Education Department of China(HZKY20220178)。
