社会与情感能力是人生成功和幸福的奠基石。2021年SSES(Study on Social and Emotion-al Skills)全球首测结果发布,为开展青少年社会与情感能力的国际比较研究提供了坚实的数据基础。本文运用DEA(Data Envelope Analysis)方法,将班级规...社会与情感能力是人生成功和幸福的奠基石。2021年SSES(Study on Social and Emotion-al Skills)全球首测结果发布,为开展青少年社会与情感能力的国际比较研究提供了坚实的数据基础。本文运用DEA(Data Envelope Analysis)方法,将班级规模、教师学历、SSES培训、SSES措施、校园活动作为投入变量,将五大能力作为产出变量,对参加本次国际测评的10座城市的1171所中小学进行培养成效评估,结果发现:(1)各城市中小学的社会与情感能力培养成效普遍较高,小学阶段的均值在0.8以上,中学阶段的均值在0.9以上;(2)在小学阶段,苏州学校的培养成效较为突出,不仅均值最高,而且整体属于高水平均衡型;在中学阶段,培养成效较为突出的城市则是伊斯坦布尔,属于高水平均衡型;(3)各城市共有82所高绩效小学和87所高绩效中学,其中伊斯坦布尔和波哥大的占比较大;(4)学校归属感对各城市中小学的社会与情感能力培养成效提升具有重要促进作用。根据以上研究结果,本文建议应该加强社会与情感能力的国际合作与实证研究,在总结苏州成功经验的同时寻找差距补齐短板,将优质均衡作为我国中小学社会与情感能力培养工作的重要目标。展开更多
Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transportation of red blood cells (RBCs) in blood vessels, leading to various clinical complications. Sickle cell disease is a widesprea...Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transportation of red blood cells (RBCs) in blood vessels, leading to various clinical complications. Sickle cell disease is a widespread genetic disease in Black Africa. The objective of this study was to evaluate the sickling inhibition activity of Griffonia simplicifolia. Quantitative and qualitative tests were used to determine the major groups of secondary metabolites present in the Griffonia simplicifolia leaves extracts and the modified Emmel test was used to perform the study of sickling inhibition activity. The OECD 423 toxicity study showed that at a single dose of 2000 mg/kg bw, Griffonia simplicifolia leaves extracts are not toxic. All tested substances inhibit erythrocyte falciformation in a dose-dependent manner. The percentages of inhibition were 50.35%, 73% and 94.23% for aqueous extract, hydromethanolic extract and phenylalanine respectively at the concentration of 15 mg/mL. The methanolic extract (70%) had higher activity compared to the aqueous extract. These results suggest that the Griffonia simplicifolia extracts have some potential to be used as alternative antisickling therapy in SCD management.展开更多
文摘社会与情感能力是人生成功和幸福的奠基石。2021年SSES(Study on Social and Emotion-al Skills)全球首测结果发布,为开展青少年社会与情感能力的国际比较研究提供了坚实的数据基础。本文运用DEA(Data Envelope Analysis)方法,将班级规模、教师学历、SSES培训、SSES措施、校园活动作为投入变量,将五大能力作为产出变量,对参加本次国际测评的10座城市的1171所中小学进行培养成效评估,结果发现:(1)各城市中小学的社会与情感能力培养成效普遍较高,小学阶段的均值在0.8以上,中学阶段的均值在0.9以上;(2)在小学阶段,苏州学校的培养成效较为突出,不仅均值最高,而且整体属于高水平均衡型;在中学阶段,培养成效较为突出的城市则是伊斯坦布尔,属于高水平均衡型;(3)各城市共有82所高绩效小学和87所高绩效中学,其中伊斯坦布尔和波哥大的占比较大;(4)学校归属感对各城市中小学的社会与情感能力培养成效提升具有重要促进作用。根据以上研究结果,本文建议应该加强社会与情感能力的国际合作与实证研究,在总结苏州成功经验的同时寻找差距补齐短板,将优质均衡作为我国中小学社会与情感能力培养工作的重要目标。
文摘Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and transportation of red blood cells (RBCs) in blood vessels, leading to various clinical complications. Sickle cell disease is a widespread genetic disease in Black Africa. The objective of this study was to evaluate the sickling inhibition activity of Griffonia simplicifolia. Quantitative and qualitative tests were used to determine the major groups of secondary metabolites present in the Griffonia simplicifolia leaves extracts and the modified Emmel test was used to perform the study of sickling inhibition activity. The OECD 423 toxicity study showed that at a single dose of 2000 mg/kg bw, Griffonia simplicifolia leaves extracts are not toxic. All tested substances inhibit erythrocyte falciformation in a dose-dependent manner. The percentages of inhibition were 50.35%, 73% and 94.23% for aqueous extract, hydromethanolic extract and phenylalanine respectively at the concentration of 15 mg/mL. The methanolic extract (70%) had higher activity compared to the aqueous extract. These results suggest that the Griffonia simplicifolia extracts have some potential to be used as alternative antisickling therapy in SCD management.
